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The complete inventory of the yeast Saccharomyces cerevisiae P
The complete inventory of the yeast Saccharomyces cerevisiae P

... clustered in 6 different families, using the phylogenetic relations determined by the PHYLIP program (Fig. 1). The prediction of the transmembrane topology of these proteins given in Fig. 2 supports the grouping into the 6 families identified by the phylogenetic approach. On the basis of predicted t ...
Rice Bioinformatics. Analysis of Rice Sequence Data and
Rice Bioinformatics. Analysis of Rice Sequence Data and

... Rice (Oryza sativa) is a model species for monocotyledonous plants, especially for members in the grass family. Several attributes such as small genome size, diploid nature, transformability, and establishment of genetic and molecular resources make it a tractable organism for plant biologists. With ...
mthfr - SpectraCell Laboratories
mthfr - SpectraCell Laboratories

... • 5-Methyl-THF slows the rate of FAD release in both the wild-type and mutant enzymes. • Mutations in the MTHFR gene could be one of the factors leading to increased risk of developing chronic diseases and psychiatric problems. “Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymo ...
Bitter Taste Study in a Sardinian Genetic Isolate
Bitter Taste Study in a Sardinian Genetic Isolate

... 131 individuals clustering in a unique large multi-generation pedigree comprising a total of 239 individuals. These individuals were used in the linkage analysis. All individuals participating in the study signed informed consent forms and all samples were taken in accordance with the Declaration of ...
pdf
pdf

... If Pc group genes play related roles in the control of en and homeotic genes, we expect a parallel in their effect on expression of these genes. Using in situ hybridization to examine the expression of Abd-B, a homeotic gene that controls the developmental fate of the more posterior abdominal segmen ...
GCF (K-13): sc-133418 - Santa Cruz Biotechnology
GCF (K-13): sc-133418 - Santa Cruz Biotechnology

... GCF (GC-rich sequence DNA-binding factor), also known as C2orf3 (chromosome 2 open reading frame 3), transcription factor 9 (TCF-9) or DNABF, is a 781 amino acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds the GC-rich sequences of β-Actin, EGFR and calciumdependent pr ...
COMPLEMENT
COMPLEMENT

... Complement Deficiencies and Associated Disease Hereditary Angioneurotic Edema – C1 INH deficiency – failure to regulate C1 resulting in fluid accumulation, epiglottal swelling. Paroxysmal Nocturnal Hemoglobinurea – CD55 and CD59 failure to function – lack of complement regulation leads to RBC lysis. ...
Altered pathogenicity, immunity, tissue tropism and 3` genome
Altered pathogenicity, immunity, tissue tropism and 3` genome

... subunit occurred between P3 and P40 and all subpopulations in a virus passage showed the same substitutions. Other substitutions that occurred between P70 and P110, however, were found only in some subpopulations of the virus passages. A 109-bp deletion in the 3'-UTR was observed in most subpopulati ...
Identification and Microsatellite Markers of a Resistance Gene to
Identification and Microsatellite Markers of a Resistance Gene to

... is a complex locus, and composed of 4, 10, 2, and 5 alleles, respectively (Hsam et al., 1998; Zeller et al., 1998; Huang et al., 2003). In our study, we located the gene PmDR147 on the distal region of long arm of chromosome 2A. Powdery mildew resistance genes Pm4a and Pm4b are also located on chrom ...
Kelp Fly Virus - Journal of General Virology
Kelp Fly Virus - Journal of General Virology

... rows c and d particles in twofold orientation, giving rise to our belief that their structure is icosahedral. In addition frames b2, b3, b4, and b5 show the proiecting subunits not merely at the periphery but also in end view in the particle surface. The large frame at lower right ( x 2ooooo) shows ...
Ge´nie: literature-based gene prioritization at multi genomic scale
Ge´nie: literature-based gene prioritization at multi genomic scale

... to screen for genes associated with particular properties, which can then be further used to design new experiments or to prioritize analysis (1). Classically, the literature dealing with genes, as stored in the MEDLINE database of biomedical references (2), has been used to do this prioritization ( ...
The expression of a chromoplast-specific lycopene beta cyclase
The expression of a chromoplast-specific lycopene beta cyclase

... identification of consensus patterns in unaligned DNA sequences (Hertz and Stormo, 1995) and by FOOTPRINTER (Blanchette and Tompa, 2003). The FOOTPRINTER takes into account the evolutionary relationships and distances between the genes compared (based on a phylogenetic tree). In order to choose adeq ...
A GENETIC LINKAGE MAP OF Phycomyces blakesleeanus
A GENETIC LINKAGE MAP OF Phycomyces blakesleeanus

... immunosuppressive disorders, solid-organ or bone marrow transplantation) and can be acute as well as chronic. The genome sequence of R. oryzae was recently published (Ma et al. 2009). Certain genetic factors in this fungal genome are thought to influence its ability to cause disease in contrast to n ...
Alterations in gene expression in T1α null lung: a model of deficient
Alterations in gene expression in T1α null lung: a model of deficient

... birth due to respiratory failure. Collectively these observations suggest that formation of alveolar sacs of appropriate dimensions, surface area, and thickness is of fundamental importance in lung organogenesis and is critical for survival. We have previously shown that mice carrying a null mutatio ...
The coiled-coil of the human Rad50 DNA repair protein contains
The coiled-coil of the human Rad50 DNA repair protein contains

... globular ATPase domain made up from the N and C termini of the protein separated by an extensive central region predicted to form a coiled-coil (2). Accumulated recent evidence reveals that Rad50 and other SMC proteins are arranged as intramolecular coiled-coils bringing together the N and C termini ...
Mammals Differences between the Chicken and Antagonist in the
Mammals Differences between the Chicken and Antagonist in the

... COP9 signalosome, an important protein kinase involved in signal transduction. This causes inhibition of downstream proinflammatory cytokine production (12). Second, icIL-1RN1 may act within the nucleus to inhibit the effects of IL-1a. Briefly, either full-length IL-1a or its N-terminal propiece inc ...
Document
Document

... § AA ((severelyy affected)) > Aa ((slightly g y affected)) > aa ((normal)) ...
Differential mRNA expression levels and gene sequences of a
Differential mRNA expression levels and gene sequences of a

... Belmont, CA) with a PCR-amplified carboxylesteraselike cDNA probe labeled with α⫺32P-dCTP (Amersham, Arlington Heights, IL). Membranes were washed at 55°C for 1 h with three changes of 0.2×SSC (sodium chloride/sodium citrate)/0.1% SDS and then exposed to X-ray films. Positive clones from the first l ...
A statistical framework for genome
A statistical framework for genome

... This joint analysis can elicit a significant biological effect even if changes in any individual gene have a small effect or is not significant at all. Importantly, this setting has been considered as being dominant in many pathological processes 1; 2. Third, single-factor analyses can result in a h ...
Answer
Answer

... Genetics Lingo for 800 Question: A general rule in inheritance that individuals have two alleles for each gene, and that when gametes form by meiosis, the two alleles separate, and each resulting gamete ends up with only one allele of each gene. ...
What Are Chromosomes?
What Are Chromosomes?

... Normal Chromosomes  Normal human somatic cells have 46 chromosomes: 22 pairs, or homologs, of autosomes (chromosomes 1-22) and two sex chromosomes. This is called the diploid number. Females carry two X chromosomes (46,XX) while males have an X and a Y (46,XY).  Germ cells (egg and sperm) have 23 ...
"Genetic Redundancy".
"Genetic Redundancy".

... The a-actins are actin-binding proteins forming a major structural component of the Z-lines in myofilaments. Early studies implicated the loss of ACTN3 (a-actinin-3) in muscular dystrophy, and other dystrophic, myopathic and neurogenic pathologies. Subsequent testing revealed that normal individuals ...
Molecular evidence that epizootic Venezuelan equine encephalitis
Molecular evidence that epizootic Venezuelan equine encephalitis

... within or near this domain of the E2 proteins of both EVE and MENA viruses probably account for much of their differential antigenicity in polyvalent (Young & Johnson, 1969; France et al., 1979) and monoclonal (Roehrig et al., 1982; Roehrig & Mathews, 1985) antibody analyses. Other E1 and E2 amino a ...
Printable version
Printable version

... was successful where many before him had failed because: ¾ He simplified the problem by first examining just one trait at a time. ¾ He limited his study to traits that existed in 2 discrete forms. ¾ He kept quantitative data over several generations, and used large sample sizes. ...
PDF
PDF

... Terminal Coding Fragment (TCF)—presents some unique challenges. Many of these stem from the widely varying length of TCFs. Human TCFs range from only one or two bases up to several kilobases. Consider, then, the problem of identifying the correct stop codon given a terminal exon’s acceptor site. In ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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