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Histone modifications and exercise adaptations
Histone modifications and exercise adaptations

... promoter in C2C12 myocytes (29). Again, these effects were completely abolished in the presence of CaMK inhibitors. Reduced neuromuscular activity, as occurs with denervation, has been shown to increase the nuclear abundance of HDAC4 and alter the expression of genes encoding myogenic factors and th ...
Chapter 8: Chromosomes and Chromosomal Anomalies
Chapter 8: Chromosomes and Chromosomal Anomalies

... In the propagation of a sperm, nondisjunction may occur so that one gamete inherits two Y chromosomes while the other gamete inherits no sex chromosomes. If the gamete with no sex chromosomes fertilizes an egg, the resulting zygote will be inviable and will die in utero (i.e., within the mother’s wo ...
DNA - CS.Duke
DNA - CS.Duke

... The   code   in   the   class  DNABenchMark   can   be   used   to   benchmark   the  cutAndSplice  method.   The   code   given   to   you   will   pop-­‐up   a   file-­‐dialog   box   —   when   run   you   can   use   this   to   nav ...
univERsity oF copEnhAGEn
univERsity oF copEnhAGEn

... See Geographical race, Race, Sympatric. Allozyme (alloenzyme): An isozyme which differs from other variants of the enzyme as a result of allelic difference, i.e different enzymes coded by the same gene locus. See Allele, Enzyme, Fingerprint, Isozyme, Marker. Aneuploidy: A condition in which not all ...
Tree Improvement
Tree Improvement

... See Geographical race, Race, Sympatric. Allozyme (alloenzyme): An isozyme which differs from other variants of the enzyme as a result of allelic difference, i.e different enzymes coded by the same gene locus. See Allele, Enzyme, Fingerprint, Isozyme, Marker. Aneuploidy: A condition in which not all ...
Gene Section SRXN1 (sulfiredoxin 1) Atlas of Genetics and Cytogenetics
Gene Section SRXN1 (sulfiredoxin 1) Atlas of Genetics and Cytogenetics

... In adult, Srx protein was found in internal organs such as mouse liver and kidney. Expression pattern of Srx in embryonic development is not clear. Transcriptional regulation of Srx expression is mainly mediated through AP-1 and/or Nrf-2 activation (Jeong et al., 2012). In yeast, it may also be nega ...
Biotechnology Timeline
Biotechnology Timeline

... last reported cases occurred in 2004 and resulted from laboratory-acquired infections. ...
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... • Different combinations of antibiotics and inhibitors to detect MBL producers with different sensitivity and specificity – Imipenem-EDTA: P. aeruginosa and A. baumannii – Ceftazidime-CA/EDTA: K. pneumoniae – Cefepime-CA/EDTA: E. cloacae and C. freundii ...
In the beginning: the initiation of meiosis
In the beginning: the initiation of meiosis

... takes place after the animal reaches puberty. In contrast, in the testis, spermatocytes initiate meiosis throughout the life of the animal in synchronous waves starting at about a week after birth. Consequently, the signal for initiating meiosis must be regulated differently in males and females. Re ...
Trawling DNA Databases For Partial Matches: What Is The FBI
Trawling DNA Databases For Partial Matches: What Is The FBI

... DNA evidence is often presented as the “gold standard” for forensic science. But this was not always the case. For years, eminent scientists complained that the estimates of the tiny frequencies of DNA types were unfounded. It took scores of research papers, dozens of judicial opinions, and two comm ...
Ion AmpliSeq RNA Panels—quantitative targeted gene expression
Ion AmpliSeq RNA Panels—quantitative targeted gene expression

... representing 267 genes involved in the cellular apoptosis pathway, including genes associated with death receptor–, c–Myc, and p53-mediated apoptosis. Incorporating improvements in amplicon primer design, library preparation, and coverage analysis, Ion AmpliSeq™ RNA technology can provide relative a ...
Direct Sequence Analysis of the 14q+ and 18q
Direct Sequence Analysis of the 14q+ and 18q

... products. DNA from the reaction mixture was purified using a suggesting a deletion between D, and J, in t(14;18) transloSephedex G50 column followed by ethanol precipitation, freeze cation in lymphomas.’ The translocation results in a hybrid drying, and resuspension in distilled water. Sequencing wa ...
Gene Section NR1H4 (nuclear receptor subfamily 1, group H, member 4)
Gene Section NR1H4 (nuclear receptor subfamily 1, group H, member 4)

... activation by enhanced bile acid levels FXR mediates responses that partially protect the hepatocyte from the deleterious effect of accumulation of toxic bile acids. FXR inhibits bile acid synthesis in liver, through down-regulation of key enzymes in bile acid biosynthesis, such as CYP7A1 and CYP8B1 ...
Altered pathogenicity, immunogenicity, tissue tropism and 3`
Altered pathogenicity, immunogenicity, tissue tropism and 3`

... primarily in the spike (S) protein. Substitutions in the S1 subunit occurred between P3 and P40 and all subpopulations in a virus passage showed the same substitutions. Other substitutions that occurred between P70 and P110, however, were found only in some subpopulations of the virus passages. A 10 ...
Chapter Outline
Chapter Outline

... • Between humans and mice, 16 of 141 amino acid  sites in ‐globin differ, so the proportion of  different sites is 16/141 = 0.11. • Between humans and carp, the proportion of  different sites is 68/141 = 0.48. • Some sites could have mutated more than once,  so 0.48 probably underestimates the aver ...
Cambridge International Examinations Cambridge
Cambridge International Examinations Cambridge

... envelope during a mitotic cell cycle in the root tip of A. cepa. ...
NRT2 - Clark University
NRT2 - Clark University

... H.velutipes clade has, in fact, been demonstrated (Aanen, 2001). ∆ Problems with these hypotheses include the likelihood of these events being of some debate, and also the lack of additional corroborative molecular evidence such as additional ITS sequences in H. helodes. These are not necessarily fa ...
PDF - Molecular Vision
PDF - Molecular Vision

... three different chromosomal loci, with several genes in these loci being implicated. The role of both VSX1 and COL8A2 in PPCD remains controversial but recent work suggests that mutations in the transcription factor gene ZEB1/TCF8 account for disease in up to 30% of subjects, with a significant asso ...
Pre-made tetracycline regulator (TetR) expression lentiviral
Pre-made tetracycline regulator (TetR) expression lentiviral

... 5. Pick several resistant colonies and expand each clone into flask and assay for Tet repressor expression by ELISA or qRT-PCR (Note: TetR assay materials need to be obtained and is not provided with TetR particles). Alternatively, you may pool the heterogeneous population of resistant cells and as ...
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Get

... • Can divide and differentiate into any type of body cell (!!!!!) ...
Single Nucleotide Polymorphism (SNP) 分析與應用
Single Nucleotide Polymorphism (SNP) 分析與應用

ELMER: An R/Bioconductor Tool Inferring Regulatory Element
ELMER: An R/Bioconductor Tool Inferring Regulatory Element

... method, and probes were selected when they had adjusted p-value less than 0.01. For additional stringency, probes were only selected if the methylation difference: ∆ = µexperiment − µcontrol was greater than 0.3. The same method was used to identify hypermethylated probes, except we used upper exper ...
The ins and outs of sphingolipid synthesis
The ins and outs of sphingolipid synthesis

... though the biochemical pathway of sphingolipid synthesis and its compartmentalization between the endoplasmic reticulum and Golgi apparatus have been known for many years, the molecular identity of the enzymes in this pathway has only recently been elucidated. Here, we summarize progress in the iden ...
Nuclear–chloroplast
Nuclear–chloroplast

... yeast protein is required for association of the mRNA with membrane bound polysomes. Many proteins that bind to the 5′ UTRs of chloroplast transcripts, like psbA, psbC and psbD have been shown to be at least partially membrane associated, indicating a potential role in the proper localization of the ...
Affymetrix Chips
Affymetrix Chips

... ArrayExpress - A public repository for microarray based gene expression data maintained by European Bioinformatics Institute. ChipDB - A searchable database of gene expression Gene Expression Atlas - A database for gene expression profile from 91 normal human and mouse samples across a diverse array ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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