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Illustrating Python via Bioinformatics Examples
Illustrating Python via Bioinformatics Examples

... in all files can be fully automated. Every time you to a change in some file you can with minimum effort rerun all tests. The entire suite of functions presented above, including the timings and tests, can be found in the file count.py9 . ...
08.seg_dup_els - NYU Computer Science
08.seg_dup_els - NYU Computer Science

... full generality. For instance, the rates of gene duplication and deletion in different genomes had been quantified and found to be at a similar scale to the substitution rate [Lynch & Conery (2000)]. For instance, these studies had resulted in some understanding of the fate of the duplicated genes: ...
Hooked on fat: the role of lipid synthesis in cancer metabolism and
Hooked on fat: the role of lipid synthesis in cancer metabolism and

... different saturation levels. (d) Essential FAs (ω3 and ω6 FAs) cannot be synthesised by human cells and need to be provided from dietary sources. (e,f) Saturated and unsaturated FAs are combined with glycerol-3-phosphate (glycerol-3-P) to generate (e) phosphoglycerides and (f) phosphoinositides. (g) ...
Bovine Angiotensin Converting Enzyme cDNA Cloning and
Bovine Angiotensin Converting Enzyme cDNA Cloning and

... angiotensin II, a powerful vasoconstrictor and smooth muscle growth factor. ACE activity has been shown to be dynamically regulated by hormones, ACE inhibitors, and endothelial cell growth state. To study how ACE expression is regulated, we isolated and sequenced the bovine ACE gene using both ACE-s ...
Transfer of genetic material between the
Transfer of genetic material between the

... the nuclear genome of the two organelle genomes follows different paths. It is impossible to derive the origin and the specific sequence of events that resulted in the capture and control of all these chloroplast-localized functional proteins. However, the continual transfer of chloroplast sequences ...
Chromatin Signature Identifies Monoallelic Gene Expression Across
Chromatin Signature Identifies Monoallelic Gene Expression Across

... requiring a reference dataset. Consequently, the newly trained classifier can be readily applied to other datasets with gene2body signal expressed as quantile-rank, even when absolute values are on different scales due to experimental or data processing differences, as illustrated on Figure S1. As pa ...
Viral meningitis is an infection of the subarachnoid space caused by
Viral meningitis is an infection of the subarachnoid space caused by

... or without a prodrome, but can also be a slowly progressive disease as in progressive multifocal leukoencephalopathy (PML) caused by JC virus, subacute sclerosing panencephalitis (SSPE) occurring after measles, and HIV encephalopathy. E. Diagnosis of Viral Encephalitis Diagnosis begins with a thorou ...
Role for CCG-trinucleotide repeats in the pathogenesis of chronic
Role for CCG-trinucleotide repeats in the pathogenesis of chronic

... proliferation of mature B-lymphocytes increasing in incidence logarithmically with age in adults.1 Sporadic CLL may have a hereditary component because several studies report an elevated risk for hematologic malignancy2,3 and other cancers in first-degree relatives. Familial clustering of CLL does o ...
Leukaemia Section t(7;12)(q34;p13), t(12;14)(p13;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(7;12)(q34;p13), t(12;14)(p13;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... Genome Rearrangements and Cancer Group, Hematology Laboratory and U728 INSERM, Hopital SaintLouis and Paris 7 University, Paris, France Published in Atlas Database: June 2006 Online updated version: http://AtlasGeneticsOncology.org/Anomalies/t0712q34p13ID1434.html ...
Renal Cell Carcinoma: Recent Advances in Genetics and Imaging
Renal Cell Carcinoma: Recent Advances in Genetics and Imaging

... Figure 13 Osseous metastases from clear cell RCC. Axial CECT image in the pelvis from the same patient shows a lytic metastasis in the right iliac bone with enhancing soft tissue (arrow). ...
Chapter 1 - Online Open Genetics
Chapter 1 - Online Open Genetics

... and is designed for you to be able to look at a single gene symbol and determine its inheritance automatically. We will call it the Sumnospauci combibo convention (Sóo-me-no spów-see, a hypothetical organism used for genetics practice questions). We’ll build up to this by working through extensions ...
Cotranscriptional coupling of splicing factor recruitment and
Cotranscriptional coupling of splicing factor recruitment and

... To begin to investigate cotranscriptional accumulation of RNAbinding proteins, antibodies specific for the CBP80 subunit of the capbinding complex (CBC) were used for ChIP. We anticipated that the CBC should bind the 5¢ end of every capped Pol II transcript (Fig. 1). Capping occurs after only 20–30 ...
Examples of Red Algae
Examples of Red Algae

No Evidence of Neandertal mtDNA Contribution to Early Modern
No Evidence of Neandertal mtDNA Contribution to Early Modern

... sequences similar to contemporaneous humans, such sequences may be erroneously regarded as modern contaminations when retrieved from fossils. Here we address these issues by the analysis of 24 Neandertal and 40 early modern human remains. The biomolecular preservation of four Neandertals and of five ...
Missouri State Standards (Biology I End of Course Exam) Biology
Missouri State Standards (Biology I End of Course Exam) Biology

... 9. Describe the chemical and structural properties of DNA (e.g., DNA is a large polymer formed from linked subunits of four kinds of nitrogen bases; genetic information is encoded in genes based on the sequence of subunits; each DNA molecule in a cell forms a single chromosome) (Assess the concepts ...
Touring Ensembl: A practical guide to genome browsing Open Access
Touring Ensembl: A practical guide to genome browsing Open Access

... start site, binding sites for proteins such as NF-κB, AP-1, and NFAT (nuclear factor of activated T-cells), DNase I hypersensitive sites and a TATA box can all be found. These regions have been shown to be involved in the control of T-cell mediated immune response[15,16]. The ENCODE pilot study [17] ...
Chapter 6
Chapter 6

... pathological alterations that are seen during viral hepatitis are mediated mainly by cytotoxic T cells, which recognize and kill virally-infected hepatic cells.  HBV-infected liver cells express on their surfaces MHC-I molecules that are loaded with peptide antigens derived from HBV proteins, mainl ...
"PCR-based Species Identification and Gene Tagging"
"PCR-based Species Identification and Gene Tagging"

... Detection of infected progeny from a systemically infected maize plant via dot-blot hybridization using genomic P. sorghi gDNA ...
Glycolytic enzymes localize to ribonucleoprotein
Glycolytic enzymes localize to ribonucleoprotein

... cells are highly specialized and differentiate into eggs or sperm. However, the union of egg and sperm gives rise to a zygote, which is capable of producing all cell lineages in the organism of the next generation [6,7]. Germ cells in many organisms have distinct cytoplasmic structures referred to a ...
Estimating lethal allele frequencies in complex pedigrees via gene
Estimating lethal allele frequencies in complex pedigrees via gene

... expected lethal allele frequency from known individual genotypes (carriers) among a set of relevant ancestors. Here we used a Fortran program written by LIDAUER and ESSL (1994) based on a concept developed by ALLAIRE et al. (1982). With this program, only six generations of each reference animal are ...
Point mutations in BCL6 DNA-binding domain reveal distinct
Point mutations in BCL6 DNA-binding domain reveal distinct

... We show here by point mutation analysis that the six ZFs of BCL6 are not equivalent in DNA-binding activity. Similar findings were reported for the POK proteins ZF5 and Kaiso [12 and 13]. The described experiments differed from our work though, as the ZF region of these two proteins was not examined ...
File
File

... With reference to Table 4.2, and the information in (iii), state the cause or causes of reduced fertility in these mutant worms at each temperature. ...
Erp, an extracellular protein family specific to
Erp, an extracellular protein family specific to

... factor in Mycobacterium tuberculosis and was thought to be present only in Mycobacterium leprae and members of the TB complex. Here it is shown that Erp is a ubiquitous extracellular protein found in all of the mycobacterial species tested. Erp proteins have a modular organization and contain three ...
Molecular markers in Brassica Rapa
Molecular markers in Brassica Rapa

... All of the inner leafy tissues of OC and YE cultivars except for the external leaves (two or three layers) with chlorophyll were ground using an electric blender, freeze-dried, and then stored at −70 °C until use. The method to extract the carotenoids was based on the procedure established by Bohoyo ...
Supplementary Notes S1 (doc 64K)
Supplementary Notes S1 (doc 64K)

... 2. Import the target region list. Ensured that the chromosome name and coordinates specified for every region were valid. Also tested that there were no overlaps between regions in the input list. Overlaps and duplicates in the initial lists were resolved and resulted in a final list of 11,000 targe ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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