Redesign of the monomer–monomer interface of Cre recombinase
... or TAL effector domains, Cre recombinase interacts with DNA through large interfaces that defy a modular decomposition. Nevertheless, altered RT specificities have been elicited in mutant Cre recombinases using directed evolution (12–14). The quaternary structure of the Cre complex creates a second ...
... or TAL effector domains, Cre recombinase interacts with DNA through large interfaces that defy a modular decomposition. Nevertheless, altered RT specificities have been elicited in mutant Cre recombinases using directed evolution (12–14). The quaternary structure of the Cre complex creates a second ...
here in word document
... Since the high uric acid defect is fixed, worldwide, in our breed, there is no other solution. We cannot breed to unaffected Dals because they do not exist. In addition, all breeds are a mixture of several other breeds, and breeders have been improving breeds for 100’s of years by cross-breeding to ...
... Since the high uric acid defect is fixed, worldwide, in our breed, there is no other solution. We cannot breed to unaffected Dals because they do not exist. In addition, all breeds are a mixture of several other breeds, and breeders have been improving breeds for 100’s of years by cross-breeding to ...
Programmed Ribosomal Frameshifting Generates a Copper
... (Baranov et al., 2002). This term refers to a variety of scenarios in which interpretation of the genetic information deviates from the straightforward single-frame codon-by-codon translation of mRNA by the ribosomes. Among other options, recoding may involve programmed ribosomal frameshifting (PRF) ...
... (Baranov et al., 2002). This term refers to a variety of scenarios in which interpretation of the genetic information deviates from the straightforward single-frame codon-by-codon translation of mRNA by the ribosomes. Among other options, recoding may involve programmed ribosomal frameshifting (PRF) ...
mic.sgmjournals.org
... produce glutamic acid under biotin-limiting conditions. In an effort to understand C. glutamicum metabolism under biotin limitation, growth of the type strain ATCC 13032 was investigated in batch cultures and a time-course analysis was performed. A transient excretion of organic acids was observed a ...
... produce glutamic acid under biotin-limiting conditions. In an effort to understand C. glutamicum metabolism under biotin limitation, growth of the type strain ATCC 13032 was investigated in batch cultures and a time-course analysis was performed. A transient excretion of organic acids was observed a ...
Specificity of Insertion by the Translocatable Tetracycline Resistance Element Tn10.
... 1975; BOTSTEINand KLECKNER1977). TnlO is 9300 basepairs in length, with 1400-basepair inverted repetitions at its ends. These repetitions may be intact IS-like sequences (CHAN 1974; SHARP,COHENand DAVIDSON 1973; ROSS, SWAN and KLECKNERin preparation). The specificity of TnlO insertion for sites on a ...
... 1975; BOTSTEINand KLECKNER1977). TnlO is 9300 basepairs in length, with 1400-basepair inverted repetitions at its ends. These repetitions may be intact IS-like sequences (CHAN 1974; SHARP,COHENand DAVIDSON 1973; ROSS, SWAN and KLECKNERin preparation). The specificity of TnlO insertion for sites on a ...
Molecular mechanics of the interactions of spermine with DNA: DNA
... implies stabilization of double-stranded over single-stranded forms. It was found recently that polyamines also stabilize both the left-handed Z conformation (10,11) and the right-handed A conformation (12) of nucleic acids. Stabilization of specific DNA ...
... implies stabilization of double-stranded over single-stranded forms. It was found recently that polyamines also stabilize both the left-handed Z conformation (10,11) and the right-handed A conformation (12) of nucleic acids. Stabilization of specific DNA ...
24 Recombination Hotspots in Nonallelic Homologous Recombination
... rates can be several orders of magnitude more than in surrounding “cold” regions. In parallel to these developments, sufficient numbers of breakpoints of selected NAHR rearrangements have been characterized at the DNA sequence level to resolve the distribution of crossovers in these cases. This has ...
... rates can be several orders of magnitude more than in surrounding “cold” regions. In parallel to these developments, sufficient numbers of breakpoints of selected NAHR rearrangements have been characterized at the DNA sequence level to resolve the distribution of crossovers in these cases. This has ...
Phytopathology
... fragments and may be applicable for rapid identification and detection of plant pathogens associated with plants (20,21,26). An array of species-specific oligonucleotide probes representing the various pathogens of potato, built on a solid support such as a nylon membrane or microscope slide, could ...
... fragments and may be applicable for rapid identification and detection of plant pathogens associated with plants (20,21,26). An array of species-specific oligonucleotide probes representing the various pathogens of potato, built on a solid support such as a nylon membrane or microscope slide, could ...
Current Topics LNA (Locked Nucleic Acid): High
... LNA oligonucleotides have a high potential for diagnostic and therapeutic uses. This implies contact with various media containing nucleases, for example, in serum samples or directly in cells. In general, it is advantageous that modified oligonucleotides are unnatural to such an extent that nucleas ...
... LNA oligonucleotides have a high potential for diagnostic and therapeutic uses. This implies contact with various media containing nucleases, for example, in serum samples or directly in cells. In general, it is advantageous that modified oligonucleotides are unnatural to such an extent that nucleas ...
Dark matter, Quantum Gravity and Prebiotic Evolution Contents
... to developments in the model of EEG as communication tool between biological and magnetic body and led to the interpretation of bio-photons as decay products of dark EEG photons. Also bio-superconductivity is now reasonably well-understood and the model for cell membrane as Josephson junction is gen ...
... to developments in the model of EEG as communication tool between biological and magnetic body and led to the interpretation of bio-photons as decay products of dark EEG photons. Also bio-superconductivity is now reasonably well-understood and the model for cell membrane as Josephson junction is gen ...
Ribotyping of Clostridium perfringens from industrially produced
... Among 111 Cl. perfringens isolates from ground meat 107 distinctly different ribotype patterns were detected. In only four cases two Cl. perfringens isolates showed an identical ribopattern. Figure 1 shows an example of the variability of the ribotype patterns. The number of DIG labelled bands of Cl ...
... Among 111 Cl. perfringens isolates from ground meat 107 distinctly different ribotype patterns were detected. In only four cases two Cl. perfringens isolates showed an identical ribopattern. Figure 1 shows an example of the variability of the ribotype patterns. The number of DIG labelled bands of Cl ...
Real time PCR and it`s role in diagnosis
... Improving our understanding of the biology of the Plasmodium falciparum parasite is of extreme importance if we are to combat human malaria.This parasite uses the process of antigenic variation to expose the human immune system to continually changing antigens on the surface of infected red blood ce ...
... Improving our understanding of the biology of the Plasmodium falciparum parasite is of extreme importance if we are to combat human malaria.This parasite uses the process of antigenic variation to expose the human immune system to continually changing antigens on the surface of infected red blood ce ...
MOLECULAR RECOGNITION AND RESPONSE IN POLLEN AND
... of two fungal RNases, RNase T2 and RNase Rh. It is this similarity that led to the discovery that S-proteins are RNases (McClure et al 1989). The finding that RNases are employed by the pistil to reject self pollen raised the possibility that the RNase activity is responsible for growth inhibition o ...
... of two fungal RNases, RNase T2 and RNase Rh. It is this similarity that led to the discovery that S-proteins are RNases (McClure et al 1989). The finding that RNases are employed by the pistil to reject self pollen raised the possibility that the RNase activity is responsible for growth inhibition o ...
Angelique Nicole Besold - UMB Digital Archive
... absolutely no clue what I was doing. That summer changed my outlook on research and my future. I would not be writing these acknowledgements today were it not for that experience. Graciously, she took me under her wing as a laboratory technician after college and has been with me ever since. With he ...
... absolutely no clue what I was doing. That summer changed my outlook on research and my future. I would not be writing these acknowledgements today were it not for that experience. Graciously, she took me under her wing as a laboratory technician after college and has been with me ever since. With he ...
Evolutionary dynamics of nematode operons
... genes reside in over 1100 operons in the model organism Caenorhabditis elegans. It is unclear how operons have become abundant in nematode genomes. The “one-way street” hypothesis asserts that once formed by chance, operons are very difficult to break, because the breakage would leave downstream gen ...
... genes reside in over 1100 operons in the model organism Caenorhabditis elegans. It is unclear how operons have become abundant in nematode genomes. The “one-way street” hypothesis asserts that once formed by chance, operons are very difficult to break, because the breakage would leave downstream gen ...
Getting Started With Gel Electrophoresis
... that the DNA molecules stay in their deprotonated form which includes a negative charge on each phosphate group. Without that negative charge, DNA molecules would not be moved by an electric field and electrophoresis would not work. The electrolyte solution must be fairly dilute in order to minimise ...
... that the DNA molecules stay in their deprotonated form which includes a negative charge on each phosphate group. Without that negative charge, DNA molecules would not be moved by an electric field and electrophoresis would not work. The electrolyte solution must be fairly dilute in order to minimise ...
Pristionchus pacificus
... with permission from Hong and Sommer (2006), Bioessays © copyright 2006 Wiley Periodicals, Inc. Number of Ppa SNP ...
... with permission from Hong and Sommer (2006), Bioessays © copyright 2006 Wiley Periodicals, Inc. Number of Ppa SNP ...
Epigenetic Interactions among Three dTph1 Transposons in Two
... 1087, 1081 HV, Amsterdam, The Netherlands ...
... 1087, 1081 HV, Amsterdam, The Netherlands ...
Non-homologous end-joining partners in a helical dance: structural
... for example, PNKP interacts with XRCC4, both through a site phosphorylated by protein kinase CK2, as well as with the unphosphorylated protein [28,29]. XLF does not bind to LigIV, but the folded-back loop sequence between XLF α4 and α5 is evolutionarily conserved [13]. Site-directed mutagenesis stud ...
... for example, PNKP interacts with XRCC4, both through a site phosphorylated by protein kinase CK2, as well as with the unphosphorylated protein [28,29]. XLF does not bind to LigIV, but the folded-back loop sequence between XLF α4 and α5 is evolutionarily conserved [13]. Site-directed mutagenesis stud ...
![arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007](http://s1.studyres.com/store/data/014946021_1-c477dba1add7a260e278ca181f537c79-300x300.png)
arXiv:0708.2724v1 [cond-mat.other] 20 Aug 2007
... compare a plethora of individual human genomes, enabling us to locate sequences which cause hereditary diseases and to discover mutated sequences. Individual medical consumers can then be tested for these known genetic defects. Thus, medicine and treatments can be tailored to their specific conditio ...
... compare a plethora of individual human genomes, enabling us to locate sequences which cause hereditary diseases and to discover mutated sequences. Individual medical consumers can then be tested for these known genetic defects. Thus, medicine and treatments can be tailored to their specific conditio ...
chicken.db - Bioconductor
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
