Presentation - Stamm`s Lab
... developed in HTR2c knockout mice have strengthened the connection between 2c receptor and weight control. HTR2c gene undergoes extensive post-transcriptional processing including RNA editing and alternative splicing. Among all the isoforms generated from processing, the unedited, 5' splice site B-in ...
... developed in HTR2c knockout mice have strengthened the connection between 2c receptor and weight control. HTR2c gene undergoes extensive post-transcriptional processing including RNA editing and alternative splicing. Among all the isoforms generated from processing, the unedited, 5' splice site B-in ...
医学分子生物学
... as well as a TATA box or other promoter element. Enhancers may be either upstream or downstream and as far away as 50 kb from the transcription start site. In some cases, promoter-proximal elements occur downstream from the start site as well. (b) Most yeast genes contain only one regulatory region, ...
... as well as a TATA box or other promoter element. Enhancers may be either upstream or downstream and as far away as 50 kb from the transcription start site. In some cases, promoter-proximal elements occur downstream from the start site as well. (b) Most yeast genes contain only one regulatory region, ...
Chapter 8
... DNA - Macromolecule - Small chromosomes-- Million nucleotide wide - Atcg; base pairs - Complementary; 2 strands, anti parallel - Double helix - Hydrogen bonds; at core - Dehydration synthesis - Starting point 3' prime to 5' prime - Run chemical opposite direct. - 5' phosphate - 3' hydroxyl - Deoxyri ...
... DNA - Macromolecule - Small chromosomes-- Million nucleotide wide - Atcg; base pairs - Complementary; 2 strands, anti parallel - Double helix - Hydrogen bonds; at core - Dehydration synthesis - Starting point 3' prime to 5' prime - Run chemical opposite direct. - 5' phosphate - 3' hydroxyl - Deoxyri ...
What is RNA? - Manhasset Schools
... DNA is too ________________ to leave the nucleus, so a smaller molecule called __________ is made to carry the _______________________ out of the _________________ so ____________________ can be made. * This is completed through the process of _________________________________ * ...
... DNA is too ________________ to leave the nucleus, so a smaller molecule called __________ is made to carry the _______________________ out of the _________________ so ____________________ can be made. * This is completed through the process of _________________________________ * ...
LecCh6Annotation
... Noncoding RNA (ncRNA) • ncRNA represent 98% of all transcripts in a mammalian cell • ncRNA have not been taken into account in gene counts • cDNA • ORF computational prediction • Comparative genomics looking at ORF ...
... Noncoding RNA (ncRNA) • ncRNA represent 98% of all transcripts in a mammalian cell • ncRNA have not been taken into account in gene counts • cDNA • ORF computational prediction • Comparative genomics looking at ORF ...
Bio 101 Study Guide Lecture Exam 3
... • Be familiar with the Hershey-Chase experiment. • Nucleic acids are polymers made of what? • What are the 3 parts of a nucleotide? • Who are Watson and Crick? • Understand the structure of DNA (double helix, sugar-phosphate backbone, base pairing) • Know the base pairing rules (A=T & G=C). • If giv ...
... • Be familiar with the Hershey-Chase experiment. • Nucleic acids are polymers made of what? • What are the 3 parts of a nucleotide? • Who are Watson and Crick? • Understand the structure of DNA (double helix, sugar-phosphate backbone, base pairing) • Know the base pairing rules (A=T & G=C). • If giv ...
RNA processing
... – tRNA modifications include splicing, cleavage of sequences at the 5’ and 3’ end, and base modification – Mature rRNAs are cut out of a preribosomal primary transcript that includes one copy each of 18, 5.8 and ...
... – tRNA modifications include splicing, cleavage of sequences at the 5’ and 3’ end, and base modification – Mature rRNAs are cut out of a preribosomal primary transcript that includes one copy each of 18, 5.8 and ...
Ch .15 - Crestwood Local Schools
... Has 100 potential splicing sites. Could produce 38,000 different polypeptides Many of these polypeptides have been found ...
... Has 100 potential splicing sites. Could produce 38,000 different polypeptides Many of these polypeptides have been found ...
3.12 Translation
... Weirdly, they asked me to get my Biology class to solve it! Make sure you make a sketch of the ...
... Weirdly, they asked me to get my Biology class to solve it! Make sure you make a sketch of the ...
with an intron
... iii. Ribosomal RNAs (rRNA). iv. Small nuclear RNAs (snRNA), found only in eukaryotes. ...
... iii. Ribosomal RNAs (rRNA). iv. Small nuclear RNAs (snRNA), found only in eukaryotes. ...
Chapter 16 Research Discovery of DNA`s Structure and Function
... The genome of an organism contains many genes, but not all of those genes are expressed in cells. Prokaryotic Gene Expression ❖ Bacterial cells are able to modify the activity of enzymes. They can also control the production levels of enzymes and regulate gene expression. ❖ Promoter - specific nucle ...
... The genome of an organism contains many genes, but not all of those genes are expressed in cells. Prokaryotic Gene Expression ❖ Bacterial cells are able to modify the activity of enzymes. They can also control the production levels of enzymes and regulate gene expression. ❖ Promoter - specific nucle ...
Control of Eukaryotic Gene Expression (Learning Objectives)
... 6. Compare and contrast pre and post transcriptional and translational controls of gene expression 7. Explain interference RNA and its role play in post-transcriptional and translational regulation of gene expression 8. Define ubiquitin and proteosome and explain their roles in intracellular protein ...
... 6. Compare and contrast pre and post transcriptional and translational controls of gene expression 7. Explain interference RNA and its role play in post-transcriptional and translational regulation of gene expression 8. Define ubiquitin and proteosome and explain their roles in intracellular protein ...
Presentation
... related to the nucleotide sequence Some individuals may express traits from their genes where others will not based on histone modifications One twin may express a trait or get a disease that the other does not, despite same genes Schizophrenia Some cancers Etc. ...
... related to the nucleotide sequence Some individuals may express traits from their genes where others will not based on histone modifications One twin may express a trait or get a disease that the other does not, despite same genes Schizophrenia Some cancers Etc. ...
MS Word file
... transcription Promoters: Basal transcription apparatus Transcriptional activator proteins RNA polymerase II – mRNA synthesis Core promoter TATA box TATAAAA, −25 to −30 bp, binded by transcription factors Transcription and Nucleosome Structure – Chromatin modification before transcription Promoters: ...
... transcription Promoters: Basal transcription apparatus Transcriptional activator proteins RNA polymerase II – mRNA synthesis Core promoter TATA box TATAAAA, −25 to −30 bp, binded by transcription factors Transcription and Nucleosome Structure – Chromatin modification before transcription Promoters: ...
Lecture 17 Functional Genetics III Basic Approaches
... Functional genomics: Identify the function of each and every gene in the genome. Since the characterization of the function of a protein domain in one organism generally provides hint to its function in another organism, the first goal of functional genomics is to identify as many genes as possible ...
... Functional genomics: Identify the function of each and every gene in the genome. Since the characterization of the function of a protein domain in one organism generally provides hint to its function in another organism, the first goal of functional genomics is to identify as many genes as possible ...
Lecture 16: Expression of genetic information
... To outline the flow of genetic information from DNA to protein synthesis. To identify the different types of RNA To compare, the structure of DNA & RNA. To outline the general characteristics of genetic code & transcription process. To explain the importance of tRNA, mRNA & rRNA. To diagram the proc ...
... To outline the flow of genetic information from DNA to protein synthesis. To identify the different types of RNA To compare, the structure of DNA & RNA. To outline the general characteristics of genetic code & transcription process. To explain the importance of tRNA, mRNA & rRNA. To diagram the proc ...
2054, Chap. 12, page 1 I. Genes: Expression and Regulation A
... a. operons usually associated with a single pathway or function b. e.g., heat-shock proteins, glycerol catabolism 4. modulon = operons controlled by their own regulators that are also under the control of a common global regulatory protein (e.g., catabolite repression) 5. stimulon = regulatory syste ...
... a. operons usually associated with a single pathway or function b. e.g., heat-shock proteins, glycerol catabolism 4. modulon = operons controlled by their own regulators that are also under the control of a common global regulatory protein (e.g., catabolite repression) 5. stimulon = regulatory syste ...
Chapter 15 - Dr. Jennifer Capers
... different mRNAs by the inclusion of different sets of exons • 15% of known human genetic disorders are due to altered splicing • 35 to 59% of human genes exhibit some form of alternative splicing • Explains how 25,000 genes of the human genome can encode the more than 80,000 different mRNAs ...
... different mRNAs by the inclusion of different sets of exons • 15% of known human genetic disorders are due to altered splicing • 35 to 59% of human genes exhibit some form of alternative splicing • Explains how 25,000 genes of the human genome can encode the more than 80,000 different mRNAs ...
BioSc 231 2001 Exam5
... _____Which of the following statements is true regarding tryptophan biosynthesis? A. It is controlled by attenuation and not repression B. Translation controls transcription C. A high tRNATrp concentration stalls translation at the ribosome D. Tryptophan synthesis is regulated differently in eukaryo ...
... _____Which of the following statements is true regarding tryptophan biosynthesis? A. It is controlled by attenuation and not repression B. Translation controls transcription C. A high tRNATrp concentration stalls translation at the ribosome D. Tryptophan synthesis is regulated differently in eukaryo ...
Transcription – Part II
... Transcriptional Regulation - Eukaryotes 8. Regulation of gene expression in eukaryotes is considered much more complex than in prokaryotes. Why do you think that is? 9. What is the role of enhancers and silencers in transcriptional regulation? 10. Describe the three different DNA binding motifs asso ...
... Transcriptional Regulation - Eukaryotes 8. Regulation of gene expression in eukaryotes is considered much more complex than in prokaryotes. Why do you think that is? 9. What is the role of enhancers and silencers in transcriptional regulation? 10. Describe the three different DNA binding motifs asso ...
Chapter 17 Nucleotides, Nucleic Acids, and Heredity
... The Molecules of Heredity • Each cell of our bodies contains thousands of different proteins. • How do cells know which proteins to synthesize out of the extremely large number of possible amino acid sequences? • From the end of the 19th century, biologists suspected that the transmission of heredi ...
... The Molecules of Heredity • Each cell of our bodies contains thousands of different proteins. • How do cells know which proteins to synthesize out of the extremely large number of possible amino acid sequences? • From the end of the 19th century, biologists suspected that the transmission of heredi ...
Decoding mRNA
... Three types of RNA are involved in the process of protein synthesis. Each molecule has specific responsibilities. Identify the 3 different types of RNA in Figure 1. Also indicate by circling the correct answer where in the cell that type of RNA can be found. ...
... Three types of RNA are involved in the process of protein synthesis. Each molecule has specific responsibilities. Identify the 3 different types of RNA in Figure 1. Also indicate by circling the correct answer where in the cell that type of RNA can be found. ...
DNA powerpoint
... • The tRNA attaches to mRNA and hooks up the amino acids in the right order. Then it goes back out to pick up some more (like a taxi cab picking up more people to bring to the location) • The amino acids get strung along into a “necklace” and when it is complete you have a protein ...
... • The tRNA attaches to mRNA and hooks up the amino acids in the right order. Then it goes back out to pick up some more (like a taxi cab picking up more people to bring to the location) • The amino acids get strung along into a “necklace” and when it is complete you have a protein ...
DNA Replication, Transcription and Translation assessment
... Topic 2.7: DNA Replication and Protein Synthesis Assessment Statements Topic 2.7 2.7.1 Explain the process of DNA replication in eukaryotes, including the role of enzymes (helicase, DNA polymerase, RNA primase and DNA ligase), Okazaki fragments and deoxynucleoside triphosphates. 2.7.2 Explain the si ...
... Topic 2.7: DNA Replication and Protein Synthesis Assessment Statements Topic 2.7 2.7.1 Explain the process of DNA replication in eukaryotes, including the role of enzymes (helicase, DNA polymerase, RNA primase and DNA ligase), Okazaki fragments and deoxynucleoside triphosphates. 2.7.2 Explain the si ...
lec07
... • Certain hereditary diseases in humans have been found to be caused by a defective enzyme. • These observations supported the onegene, one-polypeptide hypothesis. ...
... • Certain hereditary diseases in humans have been found to be caused by a defective enzyme. • These observations supported the onegene, one-polypeptide hypothesis. ...
Non-coding RNA
A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.