What is Cytogenetics?
... • Loss of a segment of chromosome • Invariably, but not always, results in the loss of important genetic material • In this example the area in the blue brackets is not present (deleted) in its pair designated by the red arrow= 46,XXdel(1)(q24q31) • Female with a deletion of chromosome 1 on the long ...
... • Loss of a segment of chromosome • Invariably, but not always, results in the loss of important genetic material • In this example the area in the blue brackets is not present (deleted) in its pair designated by the red arrow= 46,XXdel(1)(q24q31) • Female with a deletion of chromosome 1 on the long ...
glo-3, a novel Caenorhabditis elegans gene, is required for lysosome
... Gut granules are specialized lysosome-related organelles that act as sites of fat storage in Caenorhabditis elegans intestinal cells. We identified mutations in a gene, glo-3, that is functions in the formation of embryonic gut granules. Some glo-3(-) alleles displayed a complete loss of embryonic g ...
... Gut granules are specialized lysosome-related organelles that act as sites of fat storage in Caenorhabditis elegans intestinal cells. We identified mutations in a gene, glo-3, that is functions in the formation of embryonic gut granules. Some glo-3(-) alleles displayed a complete loss of embryonic g ...
by Vanessa Di Gioacchino A thesis submitted to the Department of Biology
... the fields of human health and medicine (Bellen et al., 2010). Functional orthologs of the majority of human genes can be found in the D. melanogaster genome, with greater than 80% similarity in catalytic and other important domains (Bernards and Hariharan, 2001; Rubin, 2000). However, more than hav ...
... the fields of human health and medicine (Bellen et al., 2010). Functional orthologs of the majority of human genes can be found in the D. melanogaster genome, with greater than 80% similarity in catalytic and other important domains (Bernards and Hariharan, 2001; Rubin, 2000). However, more than hav ...
PDF
... RA-Hox1 network appears to have played key roles in these evolutionary innovations crucial for acquiring the chordate body plan. Our study also suggests that Ci-Hox1 in the endoderm functions in ASP formation. In Ciona, the inductive signal for ASP formation is thought to be mediated by fibroblast g ...
... RA-Hox1 network appears to have played key roles in these evolutionary innovations crucial for acquiring the chordate body plan. Our study also suggests that Ci-Hox1 in the endoderm functions in ASP formation. In Ciona, the inductive signal for ASP formation is thought to be mediated by fibroblast g ...
x-linked mental retardation
... expenditure is spent on ‘mental handicaps’ as defined by the International Classification of Disease (ICD) (BOX 1), which by far exceeds the costs that are related to all other ICD categories2. Together with its high burden for society and families, this renders mental retardation one of the most im ...
... expenditure is spent on ‘mental handicaps’ as defined by the International Classification of Disease (ICD) (BOX 1), which by far exceeds the costs that are related to all other ICD categories2. Together with its high burden for society and families, this renders mental retardation one of the most im ...
Loss of heterozygosity at D8S262: an early genetic event of
... Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third most common cause of cancer-related deaths worldwide [1]. Up to 80 % of HCCs develop against a background of liver cirrhosis related to hepatitis B and C virus infections. Moreover, precancerous lesions of HCC, such as dysp ...
... Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third most common cause of cancer-related deaths worldwide [1]. Up to 80 % of HCCs develop against a background of liver cirrhosis related to hepatitis B and C virus infections. Moreover, precancerous lesions of HCC, such as dysp ...
Saccharomycopsis fibuligera and Yarrowia lipol`ica
... ages of amylopectin. For the colonies of A6 and A18, clear haloes were observed after growth on YPSS for 2 d. Colonies of the intergeneric hybrid between A6 and Y. lipobtica 21501-4B also showed a clear halo around the colony on YPSS. On this medium, colonies of Y. lipobtica 21501-4B did not show a ...
... ages of amylopectin. For the colonies of A6 and A18, clear haloes were observed after growth on YPSS for 2 d. Colonies of the intergeneric hybrid between A6 and Y. lipobtica 21501-4B also showed a clear halo around the colony on YPSS. On this medium, colonies of Y. lipobtica 21501-4B did not show a ...
Manuscript - Imperial Spiral
... widespread as type IV pili (Tfp). These filaments have been observed in numerous bacterial genera (Mattick, 2002) belonging primarily to Proteobacteria but also to other phyla as diverse as Cyanobacteria (Nostoc punctiforme, Microcystis aeruginosa, Synechocystis sp.), Deinococcus-Thermus (Deinococcu ...
... widespread as type IV pili (Tfp). These filaments have been observed in numerous bacterial genera (Mattick, 2002) belonging primarily to Proteobacteria but also to other phyla as diverse as Cyanobacteria (Nostoc punctiforme, Microcystis aeruginosa, Synechocystis sp.), Deinococcus-Thermus (Deinococcu ...
WHITE PANICLE1, a Val-tRNA Synthetase
... mutants, although mRNA levels of some genes were higher in wp1 than in wild type. We found that wp1 was impaired in chloroplast ribosome biogenesis. Taken together, our results show that OsValRS2 plays an essential role in chloroplast development and regulating chloroplast ribosome biogenesis. ...
... mutants, although mRNA levels of some genes were higher in wp1 than in wild type. We found that wp1 was impaired in chloroplast ribosome biogenesis. Taken together, our results show that OsValRS2 plays an essential role in chloroplast development and regulating chloroplast ribosome biogenesis. ...
understanding heredity
... At the outset, let us have a clear notion of one very important point. When heredity is mentioned, the nurseryman will think of his varieties of Rowers, the farmer will think of his seed and crops, the physician will think of his patients with "hereditary" or "constitutional" diseases. The layman, i ...
... At the outset, let us have a clear notion of one very important point. When heredity is mentioned, the nurseryman will think of his varieties of Rowers, the farmer will think of his seed and crops, the physician will think of his patients with "hereditary" or "constitutional" diseases. The layman, i ...
Chapter 13 - Meiosis and Sexual Life Cycles
... mother’s ovum (has This could also be in a an X). sperm, but the previous slide could not be in an ovum. Ans: MalesExplain. are XY. Therefore sperm can have an X or Y (they determine sex. Females are XX and therefore the ovum can only have an X. ...
... mother’s ovum (has This could also be in a an X). sperm, but the previous slide could not be in an ovum. Ans: MalesExplain. are XY. Therefore sperm can have an X or Y (they determine sex. Females are XX and therefore the ovum can only have an X. ...
Adrenal Carcinoma - LNMI - cleare
... excretion test. The recent recognition of the relatively high prevalence of subclinical Cushing syndrome in adrenal incidentalomas (some reports suggest a prevalence as high as 5-8%) that may otherwise appear hormonally silent informs the policy of some experts to perform more ...
... excretion test. The recent recognition of the relatively high prevalence of subclinical Cushing syndrome in adrenal incidentalomas (some reports suggest a prevalence as high as 5-8%) that may otherwise appear hormonally silent informs the policy of some experts to perform more ...
Differential Gene Expression in the Siphonophore
... * E-mail: [email protected] (SS); [email protected] (CWD) ...
... * E-mail: [email protected] (SS); [email protected] (CWD) ...
Semantic integration of physiology phenotypes with an application
... technologies (Berners-Lee et al., 2001). The Semantic Web provides a stack of protocols and languages to include explicit semantics in websites. In particular, the Web Ontology Language (OWL) (Grau et al., 2008) has been designed to express and share ontologies within the Semantic Web. OWL is a lang ...
... technologies (Berners-Lee et al., 2001). The Semantic Web provides a stack of protocols and languages to include explicit semantics in websites. In particular, the Web Ontology Language (OWL) (Grau et al., 2008) has been designed to express and share ontologies within the Semantic Web. OWL is a lang ...
Application to Modify an Approved Exempt or Notifiable Low Risk
... dealing with GMOs and then sign the application form. I have read, considered and understand my responsibilities under the Gene Technology Act 2000 and agree to undertake the GMO dealing outlined in this application in accordance with the relevant Office of the Gene Technology Regulator guidelines a ...
... dealing with GMOs and then sign the application form. I have read, considered and understand my responsibilities under the Gene Technology Act 2000 and agree to undertake the GMO dealing outlined in this application in accordance with the relevant Office of the Gene Technology Regulator guidelines a ...
Disintegrin, hemorrhagic, and proteolytic activities of Mohave
... They inhibit cell – cell, cell – matrix interactions and signal transduction (McLane et al., 2004). Due to their binding abilities, disintegrins have a great potential in biomedical applications such as inhibiting angiogenesis and tumor progression in vivo (Markland and Zhou, 2000). However, heretof ...
... They inhibit cell – cell, cell – matrix interactions and signal transduction (McLane et al., 2004). Due to their binding abilities, disintegrins have a great potential in biomedical applications such as inhibiting angiogenesis and tumor progression in vivo (Markland and Zhou, 2000). However, heretof ...
Chapter 11 - Genetics & Meiosis Review Questions (w/...
... 34. A pea plant heterozygous for height and seed color (TtYy) is crossed with a pea plant heterozygous for height but homozygous recessive for seed color (Ttyy). If 80 offspring are produced, how many are expected to be tall and have yellow seeds? 35. What might happen if the gametes of a species ha ...
... 34. A pea plant heterozygous for height and seed color (TtYy) is crossed with a pea plant heterozygous for height but homozygous recessive for seed color (Ttyy). If 80 offspring are produced, how many are expected to be tall and have yellow seeds? 35. What might happen if the gametes of a species ha ...
The Plastidic Phosphoglucomutase from
... The P. sativum PGM mutant, rug3, has a wrinkled seed phenotype with only 1% of the seed dry weight as starch, compared with 60% in the wild type (Harrison et al., 1998). The reduction on starch synthesis in rug3 is also accompanied by a significant increase in seed lipid content, and a decreased leg ...
... The P. sativum PGM mutant, rug3, has a wrinkled seed phenotype with only 1% of the seed dry weight as starch, compared with 60% in the wild type (Harrison et al., 1998). The reduction on starch synthesis in rug3 is also accompanied by a significant increase in seed lipid content, and a decreased leg ...
Sugar and hormone connections - Department of Molecular Biology
... expression. In petiole-fed leaves, abundant sugar signals promoted sufficient ABA synthesis in the isi4 mutant, which was not a null allele like gin1 [17]. This study provides a physiologically relevant example of sugar regulation of ABA biosynthesis that is not restricted to young seedlings. It wil ...
... expression. In petiole-fed leaves, abundant sugar signals promoted sufficient ABA synthesis in the isi4 mutant, which was not a null allele like gin1 [17]. This study provides a physiologically relevant example of sugar regulation of ABA biosynthesis that is not restricted to young seedlings. It wil ...
Cancer Prone Disease Section Retinoblastoma Atlas of Genetics and Cytogenetics
... Description: 928 aa nuclear phosphoprotein. Localisation: Nucleus. Function: Involved in cell cycle regulation. Mutations Note: Mutations predisposing to retinoblastoma are one allele mutations; in retinoblastoma, both copies of the RB1 gene are mutated (two-step inactivation mechanism typical of tu ...
... Description: 928 aa nuclear phosphoprotein. Localisation: Nucleus. Function: Involved in cell cycle regulation. Mutations Note: Mutations predisposing to retinoblastoma are one allele mutations; in retinoblastoma, both copies of the RB1 gene are mutated (two-step inactivation mechanism typical of tu ...
Protein A gene expression is regulated by DNA supercoiling which
... mutant (Fournier et al., 2000). The arlS mutant formed a biofilm on polystyrene surfaces, probably because of altered activity of secreted peptidoglycan hydrolases (Fournier & Hooper, 2000). The arl locus is also involved in the regulation of several virulence factors, mainly protein A, and some sec ...
... mutant (Fournier et al., 2000). The arlS mutant formed a biofilm on polystyrene surfaces, probably because of altered activity of secreted peptidoglycan hydrolases (Fournier & Hooper, 2000). The arl locus is also involved in the regulation of several virulence factors, mainly protein A, and some sec ...
The importance of having two X chromosomes - Neuroscience
... other than mosaicism: escape from X-inactivation, X imprinting and epigenetic sinks [11]. (i) Escape from X inactivation. X inactivation is not 100% complete, because some genes are insulated from the inactivation process and are thus expressed from both X chromosomes, making expression levels inher ...
... other than mosaicism: escape from X-inactivation, X imprinting and epigenetic sinks [11]. (i) Escape from X inactivation. X inactivation is not 100% complete, because some genes are insulated from the inactivation process and are thus expressed from both X chromosomes, making expression levels inher ...
Chapter 1
... complete set of developmental instructions for creating proteins that initiate the making of a human organism Each human has approximately 20,500 genes Human genome consists of many genes that collaborate both with each other and with non-genetic factors inside and outside the body Genetic exp ...
... complete set of developmental instructions for creating proteins that initiate the making of a human organism Each human has approximately 20,500 genes Human genome consists of many genes that collaborate both with each other and with non-genetic factors inside and outside the body Genetic exp ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
... To determine whether inhibition of Merc gene expression affected development of non-mutant embryos, a sense or antisense oligodeoxynucleotide that spanned the predicted Merc translational initiation site was injected into fertilized 1-cell embryos obtained from superovulated FVB/N or C57BL/6J mice. ...
... To determine whether inhibition of Merc gene expression affected development of non-mutant embryos, a sense or antisense oligodeoxynucleotide that spanned the predicted Merc translational initiation site was injected into fertilized 1-cell embryos obtained from superovulated FVB/N or C57BL/6J mice. ...