Understanding the pathological manifestations of aromatase excess
... example, the most proximal promoter (PII) is almost exclu- concept, aromatase is expressed in the placenta of only those sively expressed in the gonadal tissues, whereas exons 1f and higher primates that secrete adrenal androgens. I.4, which are located upstream of PII, are almost exclusively expres ...
... example, the most proximal promoter (PII) is almost exclu- concept, aromatase is expressed in the placenta of only those sively expressed in the gonadal tissues, whereas exons 1f and higher primates that secrete adrenal androgens. I.4, which are located upstream of PII, are almost exclusively expres ...
Green Juice from Sprouts - Wheatgrass and Sprouts, LLC
... - Juice 4 oz pea sprouts and 4 oz of sunflower sprouts - Cut the cucumber lengthwise (leave the skin on, if organic) and juice 8 oz cucumber juice on top of the sprouts juice - Add some celery & asparagus as water carriers and herbs, for final touch - This recipe gives you 16 oz of juice; you can do ...
... - Juice 4 oz pea sprouts and 4 oz of sunflower sprouts - Cut the cucumber lengthwise (leave the skin on, if organic) and juice 8 oz cucumber juice on top of the sprouts juice - Add some celery & asparagus as water carriers and herbs, for final touch - This recipe gives you 16 oz of juice; you can do ...
Environmentally Induced Plasticity of Root Hair Development in
... of underlying cortical cells, roots of ⫺Fe plants were characterized by a high percentage of extra hairs with two tips. Root hair patterning and hair length was differentially affected by the presence or absence of phosphate and Fe among the genotypes under investigation, pointing to separate cascad ...
... of underlying cortical cells, roots of ⫺Fe plants were characterized by a high percentage of extra hairs with two tips. Root hair patterning and hair length was differentially affected by the presence or absence of phosphate and Fe among the genotypes under investigation, pointing to separate cascad ...
An Introduction to RNA Interference (RNAi)
... numerous times to specifically silence genes with the expected biological outcome not only in cultured cells ex vivo, but also in animal models of human disease. In fact, RNAi is already being widely exploited by drug developers for drug target validation purposes. It is therefore not surprising tha ...
... numerous times to specifically silence genes with the expected biological outcome not only in cultured cells ex vivo, but also in animal models of human disease. In fact, RNAi is already being widely exploited by drug developers for drug target validation purposes. It is therefore not surprising tha ...
From the Department of Zoology, University of
... of these units per chromosome has not been determined yet, there is evidence that it may not be the same in all species (9, 10). For some time now the nature of the longitudinal differentiation of chromosomes into chromomeres, interchromomeric fibers, hetero-, and euchromatin has been debated. Some ...
... of these units per chromosome has not been determined yet, there is evidence that it may not be the same in all species (9, 10). For some time now the nature of the longitudinal differentiation of chromosomes into chromomeres, interchromomeric fibers, hetero-, and euchromatin has been debated. Some ...
Seed Germination of GA-Insensitive sleepy1
... GA biosynthetic genes are upregulated in seed tissues during seed germination and in the cold (Yamaguchi et al., 2001; Penfield et al., 2006). GA signaling is also required for efficient seed germination in Arabidopsis. Mutations in the SLEEPY1 (SLY1) GA signaling gene lead to increased seed dormanc ...
... GA biosynthetic genes are upregulated in seed tissues during seed germination and in the cold (Yamaguchi et al., 2001; Penfield et al., 2006). GA signaling is also required for efficient seed germination in Arabidopsis. Mutations in the SLEEPY1 (SLY1) GA signaling gene lead to increased seed dormanc ...
Geminivirus Replication Origins Have a Modular
... 1990), but AL3 is necessary for efficient accumulation of viral DNA in plants (Elmer et al., 1988) and in protoplasts (Sunter et al., 1990). There is strong amino acid sequence and functional conservation among the AL1 and AL3 proteins encoded by geminiviruses with bipartite genomes (Howarth and Van ...
... 1990), but AL3 is necessary for efficient accumulation of viral DNA in plants (Elmer et al., 1988) and in protoplasts (Sunter et al., 1990). There is strong amino acid sequence and functional conservation among the AL1 and AL3 proteins encoded by geminiviruses with bipartite genomes (Howarth and Van ...
In hemoglobin Tocucci there was a replacement of the amino acid
... A baby was born with scaphocephaly (a condition in which the skull is abnormally long and narrow), low-set, malformed ears, micrognathia, short digits and rocker-bottom feet, heart defects. Chromosome analysis has shown that the karyotype 47, XY, 18+. What disorder does this child have? A. Down synd ...
... A baby was born with scaphocephaly (a condition in which the skull is abnormally long and narrow), low-set, malformed ears, micrognathia, short digits and rocker-bottom feet, heart defects. Chromosome analysis has shown that the karyotype 47, XY, 18+. What disorder does this child have? A. Down synd ...
Mitochondrial DNA - Circle
... their genetic information to the nucleus. The hydrogenosome, a structure involved in carbohydrate metabolism found in some Archezoans (Muller, 1992), is now thought to represent a mitochondria that has lost its genetic information completely and along with that loss, the ability to do the Krebs cycl ...
... their genetic information to the nucleus. The hydrogenosome, a structure involved in carbohydrate metabolism found in some Archezoans (Muller, 1992), is now thought to represent a mitochondria that has lost its genetic information completely and along with that loss, the ability to do the Krebs cycl ...
no isthmus and pax2.1 in zebrafish tubulogenesis
... al., 1996; Dressler and Woolf, 1999). In vertebrates, the pax2, pax5 and pax8 genes have been grouped into a common subfamily based on their sequence similarity and expression pattern. pax2/pax5/pax8 members share in common the paired domain, an octapeptide motif, and a partial homeodomain. Mice hom ...
... al., 1996; Dressler and Woolf, 1999). In vertebrates, the pax2, pax5 and pax8 genes have been grouped into a common subfamily based on their sequence similarity and expression pattern. pax2/pax5/pax8 members share in common the paired domain, an octapeptide motif, and a partial homeodomain. Mice hom ...
Splicing regulation: a structural biology perspective
... Recognizing pyrimidine-tract by Sex-lethal, U2AF65 and PTB The 3’ splice-site pyrimidine-tract is a major cis-acting element for both constitutive and alternative splicing. Several trans-acting factors have been shown to bind the pyrimidinetract resulting in activating (U2AF65) or repressing (Sex-l ...
... Recognizing pyrimidine-tract by Sex-lethal, U2AF65 and PTB The 3’ splice-site pyrimidine-tract is a major cis-acting element for both constitutive and alternative splicing. Several trans-acting factors have been shown to bind the pyrimidinetract resulting in activating (U2AF65) or repressing (Sex-l ...
In hemoglobin Tocucci there was a replacement of the amino acid
... Geneticists calculate the ____ of a trait, or the degree to which it is inherited, as the percentage of pairs in which both twins express the trait. A. heritability B. coefficient of relationship. C. empiric risk. D. none of the above E. concordance. ANSWER E Which of the following cell types is use ...
... Geneticists calculate the ____ of a trait, or the degree to which it is inherited, as the percentage of pairs in which both twins express the trait. A. heritability B. coefficient of relationship. C. empiric risk. D. none of the above E. concordance. ANSWER E Which of the following cell types is use ...
Generation and analysis of mutated clonal scFv Jiya George
... Special thanks to my family and friends in India for their prayers, love and best wishes. Last but not the least, I would like to show my deepest gratitude to my parents for their understanding and support to pursue postgraduate studies. ...
... Special thanks to my family and friends in India for their prayers, love and best wishes. Last but not the least, I would like to show my deepest gratitude to my parents for their understanding and support to pursue postgraduate studies. ...
Gbx2 is required for the morphogenesis of the mouse inner ear
... Paint-fill analysis of Gbx2 mutant inner ears Next, we investigated the gross anatomy of Gbx2–/– inner ears at 15.5 dpc using the paint-fill technique (Fig. 2). A total of 19 homozygous mutant embryos were analyzed, and a repertoire of phenotypes was observed. We divided the specimens into four cate ...
... Paint-fill analysis of Gbx2 mutant inner ears Next, we investigated the gross anatomy of Gbx2–/– inner ears at 15.5 dpc using the paint-fill technique (Fig. 2). A total of 19 homozygous mutant embryos were analyzed, and a repertoire of phenotypes was observed. We divided the specimens into four cate ...
Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail
... increased expression in ventral cells but the mesectodermal expression was unchanged. (J) In the snail homozygous background, the mesectodermal expression of wntD disappeared, and the ventral staining became stronger. (K) In twist mutant embryos, the wntD pattern was narrower but overall was similar ...
... increased expression in ventral cells but the mesectodermal expression was unchanged. (J) In the snail homozygous background, the mesectodermal expression of wntD disappeared, and the ventral staining became stronger. (K) In twist mutant embryos, the wntD pattern was narrower but overall was similar ...
REPORT OF CONSENSUS MEETING ON THE MANAGEMENT OF
... He noted that breast cancer could be either genetic or sporadic. Familial cancer included both sporadic cases and cases in which there was a genetic predisposition. The cases of genetic breast cancer in which the family carried a gene such as BRCA1 or BRCA2 were small. Many familial cases did not. S ...
... He noted that breast cancer could be either genetic or sporadic. Familial cancer included both sporadic cases and cases in which there was a genetic predisposition. The cases of genetic breast cancer in which the family carried a gene such as BRCA1 or BRCA2 were small. Many familial cases did not. S ...
Structure, expression and chromosomal location of the Oct
... other members of the POU family. After digestion with PstI, a restriction fragment length polymorphism (RFLP) was identified in C57BL/6 (B6) versus AKR and A / J . This allowed use of the congenic chromosomes listed in Fig. 1A (Flaherty et al., 1990). Whereas, the B6.K1 and B6.K3 recombinants place ...
... other members of the POU family. After digestion with PstI, a restriction fragment length polymorphism (RFLP) was identified in C57BL/6 (B6) versus AKR and A / J . This allowed use of the congenic chromosomes listed in Fig. 1A (Flaherty et al., 1990). Whereas, the B6.K1 and B6.K3 recombinants place ...
Silent polymorphisms in the RYR1 gene do not modify the
... Both conditions have been associated to mutations in human RYR1 gene (Online Mendelian Inheritance of Man #180901), located on chromosome 19q13.1. It is a large gene organized in 106 exons [9] that encodes a calcium (Ca2+) release channel known as the ryanodine receptor (RYR1) situated on skeletal m ...
... Both conditions have been associated to mutations in human RYR1 gene (Online Mendelian Inheritance of Man #180901), located on chromosome 19q13.1. It is a large gene organized in 106 exons [9] that encodes a calcium (Ca2+) release channel known as the ryanodine receptor (RYR1) situated on skeletal m ...
2006 - Genetics, development and evolution of adaptive
... pigmentation have been cloned in mice, but almost an equal number have yet to be identified (Bennett and Lamoreux, 2003), and new loci are accumulating as a result of chemical mutagenesis programs (Mouse Genome Database). In addition, complementary vertebrate systems, such as zebrafish, are providin ...
... pigmentation have been cloned in mice, but almost an equal number have yet to be identified (Bennett and Lamoreux, 2003), and new loci are accumulating as a result of chemical mutagenesis programs (Mouse Genome Database). In addition, complementary vertebrate systems, such as zebrafish, are providin ...
Environmentally Induced Plasticity of Root Hair
... of underlying cortical cells, roots of ⫺Fe plants were characterized by a high percentage of extra hairs with two tips. Root hair patterning and hair length was differentially affected by the presence or absence of phosphate and Fe among the genotypes under investigation, pointing to separate cascad ...
... of underlying cortical cells, roots of ⫺Fe plants were characterized by a high percentage of extra hairs with two tips. Root hair patterning and hair length was differentially affected by the presence or absence of phosphate and Fe among the genotypes under investigation, pointing to separate cascad ...
Head induction in the chick - Max-Planck
... et al., 1996; Varlet et al., 1997; Dattani et al., 1998). However, since these genes are expressed both in the AVE and in the node/mesendoderm, the definitive cause of these defects remained unclear. Several other experiments have addressed the role of the visceral endoderm more directly. Chimeric m ...
... et al., 1996; Varlet et al., 1997; Dattani et al., 1998). However, since these genes are expressed both in the AVE and in the node/mesendoderm, the definitive cause of these defects remained unclear. Several other experiments have addressed the role of the visceral endoderm more directly. Chimeric m ...
Untitled - System Components
... assuming that a gene cannot have an effect outside of its principal module; however, effects of single genes on multiple phenotypes (pleiotropy) are very common [21]. Likewise, modules themselves can have pleiotropic effects [22]. It is the failure to distinguish between gene and modular pleiotropy ...
... assuming that a gene cannot have an effect outside of its principal module; however, effects of single genes on multiple phenotypes (pleiotropy) are very common [21]. Likewise, modules themselves can have pleiotropic effects [22]. It is the failure to distinguish between gene and modular pleiotropy ...
PowerPoint Presentation - Презентация PowerPoint
... Iron-sulfur (Fe-S) proteins are present in all living organisms and play important roles in electron transport and metalloenzyme catalysis [1]. Although Fe-S clusters can be assembled into proteins in vitro from Fe2+ and S2, it is clear that in vivo this process must be facilitated by protein factor ...
... Iron-sulfur (Fe-S) proteins are present in all living organisms and play important roles in electron transport and metalloenzyme catalysis [1]. Although Fe-S clusters can be assembled into proteins in vitro from Fe2+ and S2, it is clear that in vivo this process must be facilitated by protein factor ...
Brahman Genetics Negatively Impact Protein Degradation and
... cause of tougher steaks is commonly attributed to Brahman cattle having a greater calpastatin activity which inhibits calpains, the enzymes responsible for myofibrillar protein degradation during the postmortem aging process. Some researchers have reported calpastatin activity was poorly correlated ...
... cause of tougher steaks is commonly attributed to Brahman cattle having a greater calpastatin activity which inhibits calpains, the enzymes responsible for myofibrillar protein degradation during the postmortem aging process. Some researchers have reported calpastatin activity was poorly correlated ...
(NF1). - The Neuro Foundation
... When a parent has segmental NF1 the chance of passing on NF1 is much less: mostly those children will not have NF1. However if they do have NF1, their child will develop the more usual “generalised” form of NF1, with the NF1 genetic miscopy in every cell of their body. The reason this happens is be ...
... When a parent has segmental NF1 the chance of passing on NF1 is much less: mostly those children will not have NF1. However if they do have NF1, their child will develop the more usual “generalised” form of NF1, with the NF1 genetic miscopy in every cell of their body. The reason this happens is be ...