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Educator Materials
Educator Materials

... Constitutive pigmentation, or the pigmentation we are born with, is a polygenic trait, and many of the genes involved have been identified. These genes code for the enzymes that affect melanin synthesis and for the packaging, distribution, and degradation of melanosomes. Mutations in some of these g ...
Meiosis - Myersbiology
Meiosis - Myersbiology

... • Somatic cells = any cell other than gametes, most of the cells in the body. • Gametes produced by Generalized animal life cycle meiosis. Meiosis KM ...
A Bayesian Network Classification Methodology for Gene
A Bayesian Network Classification Methodology for Gene

... the laws of probability that once a conditional distribution is associated with each node, specifying the probability that the node assumes a given value conditioned on the values assumed by the node’s parents, a joint distribution for the entire set of random variables is uniquely determined. Algor ...
Basement membranes - Development
Basement membranes - Development

... molecular mechanisms of the supramolecular assembly of basement membranes, the contributions of individual proteins is not yet fully understood. Members of the collagen IV family (Kühn, 1995) are found in all basement membranes and are characterized by their ability to form complex, covalently linke ...
B/b
B/b

... Random chromatid assortment (Quadrivalents are formed):  Requirements for double reduction (requires that after crossing over between the centromere and gene marker in adjacent chromosomes, these chromosomes go to the same pole at anaphase I ): ...
Introduction
Introduction

... insertion in the middle of a gene would halt the production of the expressed protein. By knowing the phenotype the insertion line, a putative function for the gene can be ascertained. The group carried out enough insertions to ensure coverage of the entire genome (usually just one TDNA per plant), ...
Divinyl Chlorophyll(ide) a Can Be Converted to Monovinyl
Divinyl Chlorophyll(ide) a Can Be Converted to Monovinyl

... the green sulfur bacterium Chlorobium tepidum TLS. They also considered that BchJ, which had been reported to be a vinyl reductase (Suzuki and Bauer, 1995), is not the enzyme, but it may play an important role in substrate channeling and/or regulation of bacteriochlorophyll biosynthesis. Islam et al ...
Chromosomal breakpoint positions suggest a direct role for radiation
Chromosomal breakpoint positions suggest a direct role for radiation

... properties, but was not sucient for transformation (Santoro et al., 1993). However, malignant phenotype was obtained by cotransfection with H-RAS or K-RAS oncogenes. An alternative to the direct pathway is that radiation does not act directly to produce the RET/PTC3 fusion, but instead may cause pe ...
A Pseudomonas syringae pv. tomato DC3000 mutant
A Pseudomonas syringae pv. tomato DC3000 mutant

... derivative of pRK415 and PCR entry clones that contain an FRT cassette ligated between sequences flanking the deleted target gene. The cassette-marked region can be rapidly ...
biology-pre-test-questions
biology-pre-test-questions

... D) epair. 70) Which of the following is true of malignant tumors? A) They do not require treatment. B) They are easily removed through surgery. C) They can cause tumors in other parts of the body. D) They contain cells that stay clustered together. 71) One difference between a cancer cell and a norm ...
Journal of Bacteriology
Journal of Bacteriology

... Both exudate and bacteria appeared to be required to obtain active filtrates (Fig. 1A through D). Filtrates obtained after incubation of the Sym plasmidless strain RBL1387 in exudate induced neither the Tsr phenotype (Table 1) nor the Hai or Had phenotype (Fig. 1E). Similar results were observed whe ...
ExamView - Fall Semester Final Exam Practice Test.tst
ExamView - Fall Semester Final Exam Practice Test.tst

... D) epair. 70) Which of the following is true of malignant tumors? A) They do not require treatment. B) They are easily removed through surgery. C) They can cause tumors in other parts of the body. D) They contain cells that stay clustered together. 71) One difference between a cancer cell and a norm ...
Mutation in the melanocortin 1 receptor is
Mutation in the melanocortin 1 receptor is

... equivalent to Glu94 in the human and feline MC1-R, Fig. 3) was initially reported in mice to be a constitutive active mutation, which codes for a dominant black coat (Robbins et al. 1993), in contrast to the feline p.Asp84Asn substitution, which is associated with a yellow colour. Thus, the murine p ...
jing is required for wing development and to establish the
jing is required for wing development and to establish the

... genomic DNA adjacent to the P element insertion site as probe. We identified four independent partial clones that were grouped into two non-overlapping families. Our cDNAs, together with additional cDNAs identified by BDGP, suggest the existence of at least four different jing transcripts that are g ...
Leukaemia Section MLL amplification in leukemia  Atlas of Genetics and Cytogenetics
Leukaemia Section MLL amplification in leukemia Atlas of Genetics and Cytogenetics

... Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies. Blood. 2004 Jan ...
Mak5 and Ebp2 Act Together on Early Pre-60S Particles and
Mak5 and Ebp2 Act Together on Early Pre-60S Particles and

... Ribosomes are the molecular machines that translate mRNAs into proteins. The synthesis of ribosomes is therefore a fundamental cellular process and consists in the ordered assembly of 79 ribosomal proteins (r-proteins) and four ribosomal RNAs (rRNAs) into a small 40S and a large 60S ribosomal subuni ...
Chapter 10: DIPLOIDY
Chapter 10: DIPLOIDY

... provides an operator to shield those remembered alleles from harmful selection in current hostile environment. Dominance acts as a genetic operator that protects remembered alleles from fast destruction [Goldberg 1989]. This memory of diploidy stores the information regarding multiple solutions, but ...
Transgenic Tobacco Plant Expressing Environmental E. coli merA
Transgenic Tobacco Plant Expressing Environmental E. coli merA

... a potent neurotoxin and one of the most detrimental and toxic environmental pollutants. Even an extremely low level of exposure to mercury can cause permanent damage to the human central nervous system. However, mercury levels have risen owing to environmental contamination from human activities, su ...
Syntabulin, a motor protein linker, controls dorsal
Syntabulin, a motor protein linker, controls dorsal

... known to activate the canonical Wnt pathway, which leads to nuclear accumulation of b-catenin. Activation of the canonical Wnt pathway in Xenopus and zebrafish embryos results in ectopic formation or expansion of the dorsal organizer, whereas its inhibition impairs dorsal axis formation and reduces ...
POSITION-EFFECT VARIEGATION AT SEVERAL
POSITION-EFFECT VARIEGATION AT SEVERAL

Strains to Theiler`s Virus Persistent Infection the Difference of
Strains to Theiler`s Virus Persistent Infection the Difference of

... Theiler’s virus causes a persistent infection with demyelination that is studied as a model for multiple sclerosis. Inbred strains of mice differ in their susceptibility to viral persistence due to both H-2 and non-H-2 genes. A locus with a major effect on persistence has been mapped on chromosome 1 ...
study
study

... Here, by rigorous analysis of RNA-sequencing (RNAseq) data from the GTEx project [27, 28], we have comprehensively mapped, for the first time, human adults sex-differential gene expression over 45 tissues common to both sexes. We then identified highly and moderately sex-specific genes while conside ...
Gekko 4_1 July 29
Gekko 4_1 July 29

... the transport of tyrosine into the melanosomes (Rinchik et al., 1993). Oculocutaneous albinism 3 (OCA3) affects the gene for tyrosinase-relatedprotein 1 (TRP-1). TRP-1 stabilizes tyrosinase and other enzymes in the melanosome (Carden et al., 1998). Melanin is still produced by individuals with OCA3 ...
The genetic epidemiology of idiopathic scoliosis
The genetic epidemiology of idiopathic scoliosis

... Human lysyl oxidases are enzymes involved in the modeling of collagen and elastin. Despite prior experiments in animal models suggesting a link to scoliosis, no association was found for five genes (LOX, LOX1, LOX2, LOX3, LOX4) when common polymorphisms were verified in an American population (disco ...
Biochemical but not clinical vitamin A deficiency results from
Biochemical but not clinical vitamin A deficiency results from

... plasma protein, transthyretin (TTR). It has long been recognized that the nutritional status of retinol is one factor regulating RBP secretion from the liver. Studies in rats showed that retinol regulates the rate of RBP secretion without affecting RBP synthesis (4). In cases of vitamin A deficiency ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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