Competing Interests - Saudi Medical Journal
... Table 1 summarizes the different mutations found in the β-thalassaemia and sickle cell anemia affected families. Sickle cell mutation was found in two families while βthalassaemia mutations were identified in 5 families (1 compound heterozygous and 4 homozygous). For STR-analysis in the HLA locus, w ...
... Table 1 summarizes the different mutations found in the β-thalassaemia and sickle cell anemia affected families. Sickle cell mutation was found in two families while βthalassaemia mutations were identified in 5 families (1 compound heterozygous and 4 homozygous). For STR-analysis in the HLA locus, w ...
- Lab Fabiana Perocchi
... & 2009 EMBO and Macmillan Publishers Limited All rights reserved 1744-4292/09 ...
... & 2009 EMBO and Macmillan Publishers Limited All rights reserved 1744-4292/09 ...
Puffs and PCR: the in vivo dynamics of early gene
... ecdysone titres must fall dramatically for the progression of puffing, followed by a second increase in ecdysone titre which regulates the late prepupal ecdysone response from 8 to 14 hours after pupariation. Interestingly, although some of the early puffs of the late prepupal response are in common ...
... ecdysone titres must fall dramatically for the progression of puffing, followed by a second increase in ecdysone titre which regulates the late prepupal ecdysone response from 8 to 14 hours after pupariation. Interestingly, although some of the early puffs of the late prepupal response are in common ...
National Toxicology Program Technical Reports Peer Review Panel Meeting October 29, 2013
... drosophila sex-linked recessive lethals tests, and erythrocyte micronucleus tests. In the mouse lymphoma cell mutagenicity tests, VDC was positive in the presence of exogenous metabolic activation provided by induced male rat liver S9 mix and equivocal without S9. The draft report’s proposed conclus ...
... drosophila sex-linked recessive lethals tests, and erythrocyte micronucleus tests. In the mouse lymphoma cell mutagenicity tests, VDC was positive in the presence of exogenous metabolic activation provided by induced male rat liver S9 mix and equivocal without S9. The draft report’s proposed conclus ...
X chromosome inactivation- Review
... X-inactivation X-controlling element (Xce) mapped to a 6 kb region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always ina ...
... X-inactivation X-controlling element (Xce) mapped to a 6 kb region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always ina ...
Polyploidy Enhances F Pollen Sterility Loci
... interactions between pollen sterility loci during pollen mother cell (PMC) meiosis in intersubspecific autotetraploid rice hybrids. Microarray and RNA sequencing (RNA-Seq)-based transcriptome profiling are helpful tools for characterizing molecular aspects of male and female gametophyte development in ...
... interactions between pollen sterility loci during pollen mother cell (PMC) meiosis in intersubspecific autotetraploid rice hybrids. Microarray and RNA sequencing (RNA-Seq)-based transcriptome profiling are helpful tools for characterizing molecular aspects of male and female gametophyte development in ...
Molecular and Genetic Characterization of a
... extremely rare and are likely to encode important regulatory genes. The Nr gene, which has been cloned, encodes a protein with homology to the Arabidopsis ethylene receptor ETR1 (Wilkinson et al., 1995), and the normal alleles residing at rin and nor are the subject of a map-based cloning program in ...
... extremely rare and are likely to encode important regulatory genes. The Nr gene, which has been cloned, encodes a protein with homology to the Arabidopsis ethylene receptor ETR1 (Wilkinson et al., 1995), and the normal alleles residing at rin and nor are the subject of a map-based cloning program in ...
Group of Subsystems: Nitrogen oxides metabolism
... In the first step of this pathway nitrite is formed by one of the three different types of nitrate reductases: soluble assimilatory NAS, membrane-associated respiratory NAR, and periplasmic dissimilatory NAP [2, 3]. NAS is located in the cytoplasmic compartment and participates in nitrogen assimilat ...
... In the first step of this pathway nitrite is formed by one of the three different types of nitrate reductases: soluble assimilatory NAS, membrane-associated respiratory NAR, and periplasmic dissimilatory NAP [2, 3]. NAS is located in the cytoplasmic compartment and participates in nitrogen assimilat ...
Annotation Strategy Guide - GEP Community Server
... Selecting a better supported splice site: While extension of an open reading frame is important for conserving the length of the coding exon, it is also important to consider selecting the best-supported splice site. For example, let’s look at the first coding exon (1_2365_0) of Dyrk3 in D. mojave ...
... Selecting a better supported splice site: While extension of an open reading frame is important for conserving the length of the coding exon, it is also important to consider selecting the best-supported splice site. For example, let’s look at the first coding exon (1_2365_0) of Dyrk3 in D. mojave ...
Developmental and genetic disorders in
... The most common cause of male infertility is idiopathic. Fresh insights based on genetic and molecular analysis of the human genome permit classification of formerly unexplained disorders in spermatogenesis. In this article, we review new procedures that expand diagnostic and therapeutic approaches ...
... The most common cause of male infertility is idiopathic. Fresh insights based on genetic and molecular analysis of the human genome permit classification of formerly unexplained disorders in spermatogenesis. In this article, we review new procedures that expand diagnostic and therapeutic approaches ...
JunctionSeq Package User Manual
... broader array of isoform-regulation phenomena, as well as vastly improving the detection of differentials in unannotated isoforms. JunctionSeq is not designed to detect changes in overall gene expression. Gene-level differential expression is best detected with tools designed specifically for that p ...
... broader array of isoform-regulation phenomena, as well as vastly improving the detection of differentials in unannotated isoforms. JunctionSeq is not designed to detect changes in overall gene expression. Gene-level differential expression is best detected with tools designed specifically for that p ...
PowerPoint Presentation - Презентация PowerPoint
... In the first step of this pathway nitrite is formed by one of the three different types of nitrate reductases: soluble assimilatory NAS, membrane-associated respiratory NAR, and periplasmic dissimilatory NAP [2, 3]. NAS is located in the cytoplasmic compartment and participates in nitrogen assimilat ...
... In the first step of this pathway nitrite is formed by one of the three different types of nitrate reductases: soluble assimilatory NAS, membrane-associated respiratory NAR, and periplasmic dissimilatory NAP [2, 3]. NAS is located in the cytoplasmic compartment and participates in nitrogen assimilat ...
Leukaemia Section Classification of acute myeloid leukemias Atlas of Genetics and Cytogenetics
... Although the term "de novo" is not fully appropriate (see below "secondary AML"), this category of patients is usually referred as such in the literature since MDS or chemo/radiotherapy does not usually precede them either. The most commonly identified abnormalities are reciprocal translocations: t( ...
... Although the term "de novo" is not fully appropriate (see below "secondary AML"), this category of patients is usually referred as such in the literature since MDS or chemo/radiotherapy does not usually precede them either. The most commonly identified abnormalities are reciprocal translocations: t( ...
Giant viruses, giant chimeras: The multiple evolutionary histories of
... number of genomic signatures strongly support that Mimivirus belongs to the NCLDV (Nucleo-Cytoplasmic Large ds-DNA Virus) virus family. The mimiviral genome contains genes frequently found in viruses, as those involved in genome replication, but also, and for the first time in a virus, a number of g ...
... number of genomic signatures strongly support that Mimivirus belongs to the NCLDV (Nucleo-Cytoplasmic Large ds-DNA Virus) virus family. The mimiviral genome contains genes frequently found in viruses, as those involved in genome replication, but also, and for the first time in a virus, a number of g ...
DNA methylation profiling identifies epigenetic dysregulation in
... from the control samples when comparing complete methylation profiles. For this, an unsupervised hierarchical clustering was performed which placed the diabetic islet samples as one self-contained group distinct from the control samples in the resulting dendrogram (Supplementary Figure S2). This outc ...
... from the control samples when comparing complete methylation profiles. For this, an unsupervised hierarchical clustering was performed which placed the diabetic islet samples as one self-contained group distinct from the control samples in the resulting dendrogram (Supplementary Figure S2). This outc ...
Functional features of RUNX1 mutants in acute
... HOXA9, and mutations in tumor-suppressor genes such as p53, INK4A/ARF, and RB.5,6 Coexpression of RUNX1/MDS1/EVI1 or NUP98/HOXA9 with BCR-ABL can block myeloid differentiation and induce an acute myeloid leukemia (AML) in mice, suggesting that the induction of AML involves cooperation between mutati ...
... HOXA9, and mutations in tumor-suppressor genes such as p53, INK4A/ARF, and RB.5,6 Coexpression of RUNX1/MDS1/EVI1 or NUP98/HOXA9 with BCR-ABL can block myeloid differentiation and induce an acute myeloid leukemia (AML) in mice, suggesting that the induction of AML involves cooperation between mutati ...
In vivo evidence for the prokaryotic model of extended codon
... would not affect its aminoacylation. We used a RNA ®lter hybridization approach to address both questions, as shown in Figure 2. The ®rst strains constructed for this analysis were U-AUG+A (expressing an ectopic WT trnfM gene) and U-AUG+U (expressing a U37 mutant tRNA). Comparison of lanes 1 and 3 i ...
... would not affect its aminoacylation. We used a RNA ®lter hybridization approach to address both questions, as shown in Figure 2. The ®rst strains constructed for this analysis were U-AUG+A (expressing an ectopic WT trnfM gene) and U-AUG+U (expressing a U37 mutant tRNA). Comparison of lanes 1 and 3 i ...
Testing the ABC floral-organ identity model: expression of
... AP3 and PI are first expressed in stage three flowers in non-identical but overlapping domains. Only cells in the second and third whorl presumptive region (where both genes are expressed) continue to express AP3 and PI past stage 4. Neither AP3 nor PI are expressed past stage 4 in either Ap3 or Pi ...
... AP3 and PI are first expressed in stage three flowers in non-identical but overlapping domains. Only cells in the second and third whorl presumptive region (where both genes are expressed) continue to express AP3 and PI past stage 4. Neither AP3 nor PI are expressed past stage 4 in either Ap3 or Pi ...
Waleed Abdellatief Abd elhleem _paper manuscript
... importance of cytokine network genes. Tumour necrosis factor (TNF)-α, an important proinflammatory cytokine, exerts a variety of physiological and pathogenic effects, including the activation of a cascade of inflammatory events, which lead to tissue destruction in autoimmune diseases [4–6]. TNF-α st ...
... importance of cytokine network genes. Tumour necrosis factor (TNF)-α, an important proinflammatory cytokine, exerts a variety of physiological and pathogenic effects, including the activation of a cascade of inflammatory events, which lead to tissue destruction in autoimmune diseases [4–6]. TNF-α st ...
Unit F215 - Control, genomes and environment - Medium band
... Explain how the use of a different substrate is determined by the interaction between genes and the environment. ...
... Explain how the use of a different substrate is determined by the interaction between genes and the environment. ...
induction of instability at selected loci in maize
... What are “Jumping Genes”? Jumping genes, or transposable genetic elements: ...
... What are “Jumping Genes”? Jumping genes, or transposable genetic elements: ...
Restriction Fragment Length Polymorphism of hsp70
... Previous studies from our laboratory have demonstrated that the intermediate phenotype of thermosensitivity is present in hypertensive mice and rats. Increased expression of hsp70 caused by increased transcription rate was demonstrated in vivo, in organs, and in cultured cells from spontaneously hyp ...
... Previous studies from our laboratory have demonstrated that the intermediate phenotype of thermosensitivity is present in hypertensive mice and rats. Increased expression of hsp70 caused by increased transcription rate was demonstrated in vivo, in organs, and in cultured cells from spontaneously hyp ...