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Genes can be switched on and off by the protein CTCF
Genes can be switched on and off by the protein CTCF

... Genes can be switched on and off by the protein CTCF Kristina Jonas The complex development of mammals requires that the majority of all genes can be switched off at any given time. Cell and tissue-specific inactivation is a characteristic feature of many developmentally regulated genes. Inactivatio ...
A common mechanism for ATP hydrolysis in ABC transporter and
A common mechanism for ATP hydrolysis in ABC transporter and

... Cα atoms of 3.4 Å and 2.6 Å, respectively (Table 1). Interestingly, the next two structural neighbours identified by the search were the RecA protein and the helicase domain of the bacteriophage T7 helicase–primase with Z scores of 7.4 and 8.3, and rmsd values of 3.3 Å and 3.6 Å, respectively. The s ...
Loss And Gain Of Function Experiments Implicate TMEM18
Loss And Gain Of Function Experiments Implicate TMEM18

... intake at 2 weeks (Fig 4I) and DEXA scanning at 6-weeks post-surgery showed a significant difference in both total and fat mass between the two groups of mice (Fig 4J). TMEM18 contains four, not three, transmembrane domains TMEM18 has been described to be a three transmembrane protein that localizes ...
49 fv protein synth.p65
49 fv protein synth.p65

... one for each amino acid. One end contains a triplet of exposed nucleotides called the anticodon, which is complementary to one of the codons found on the mRNA (Fig 1). The other end of the tRNA molecule has a site for the attachment of a specific amino acid. The amino acid which becomes attached mus ...
2007-10_GO-resources_jblake
2007-10_GO-resources_jblake

... The first column is the gene or gene product symbol and name; clicking on the name will take you to the AmiGO gene product detail page, which shows the information held in the GO database about that gene product, including all its GO annotations and the peptide sequence (if available). By clicking ...
E I in cortical neuron balance
E I in cortical neuron balance

... Block of GABAARs stimulates the formation of inhibitory synapses in situ After 2.5 h in ACSF+BMI 50 µM After 2.5 hr in ACSF P1 superior colliculus slices ...
Your World - URMC - University of Rochester
Your World - URMC - University of Rochester

... The activities may be done as part of a “cancer unit” or divided into class or homework activities scattered through the school year. Note: * Indicates an activity that may be done as homework. Part 1: A Life Threatening Disease Students are introduced to Anna, a young woman with cancer. Students de ...
Chapter 13 - Microbial Genetics
Chapter 13 - Microbial Genetics

... A) The lac operon will be always induced B) The lac operon will never be induced C) The lac operon will be induced whenever glucose is absent, regardless of the presence or absence of lactose D) The lac operon will be induced only when both glucose and lactose are present E) The lac operon will be i ...
Presentation - University of Warwick
Presentation - University of Warwick

... Project Supervisors: ...
1 - DORAS
1 - DORAS

... dihydroxamates, namely, aerobactin, arthrobactin and schizokinen. However, it primarily differs in that it contains an additional fatty acid residue. This may account for its amphiphilic properties. The genes encoding the biosynthesis and regulation of this siderophore in S. meliloti 2011 have been ...
Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene
Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene

... Figure 1.—(A) Hypothesized components of a mitochondrial UPR. Physiological and developmental cues impose an unfolded protein load on the mitochondria. The resultant physiological stress activates the afferent limb of the UPRmt, increasing expression of genes encoding mitochondrial chaperones. The l ...
Cotranscriptional coupling of splicing factor recruitment and
Cotranscriptional coupling of splicing factor recruitment and

... of topoisomerase I activity are distributed throughout the FOS gene treatment did not impair splicing of MYC pre-mRNA (data not and have been mapped with camptothecin19, raising the possibility shown) and that all of the factors under study remain nuclear after that camptothecin may create physical ...
Regulation of Na/K-ATPase β1 -subunit gene
Regulation of Na/K-ATPase β1 -subunit gene

... including that of Na/K-ATPase α3 subunit, in cultured neonatal rat cardiac myocytes. The aim of this work was to determine whether ouabain and other hypertrophic stimuli affect Na/K-ATPase β1 subunit gene expression. When myocytes were exposed to non-toxic concentrations of ouabain, ouabain increase ...
Overexpression of Rice OSH Genes Induces Ectopic
Overexpression of Rice OSH Genes Induces Ectopic

... class 1 homeobox genes from rice: OSH1, OSH3, OSH6, OSH10, OSH15, OSH43, and OSH71 (Sentoku et al., 1999). When the homeobox gene OSH1 was overexpressed in transgenic rice plants under the control of the 35S promoter, unique phenotypic alterations in leaf structure, ligule displacement, and loss of ...
Document
Document

... genes identical on homologous chromosomes? Not necessarily, notice in the picture the darker and lighter version of the genes. Are genes always at the same location (locus) on the ...
Exercise 11 - Genetics - Lake
Exercise 11 - Genetics - Lake

... allele is recessive (“a”). Use Punnett Squares to calculate genotypic and phenotypic proportions for the parental generation crosses indicated and denote which F1 genotypes (if any) will be ...
Two enhancer regions in the mouse En-2 locus
Two enhancer regions in the mouse En-2 locus

... et al., 1991). In the adult, En-2 is strongly expressed in cells of the internal granular layer of the cerebellum. No expression is detected in the neighbouring Purkinje cells, whereas weak expression is detectable in cells of the molecular layer (Davis et al., 1988; Davis and Joyner, 1988; K. Mille ...
PDF
PDF

... for the transduction of numerous signaling pathways. Most notably, cilia have been identified as the location for post-translational processing of GLI proteins (Goetz and Anderson, 2010). GLI proteins are transcription factors that regulate a number of cellular processes (e.g. proliferation, specifi ...
An introduction to the haemoglobinopathies
An introduction to the haemoglobinopathies

Transposons ※ Transposons are DNA elements that can hop, or
Transposons ※ Transposons are DNA elements that can hop, or

... place in DNA to another. They are also called “jumping genes”. They carry the enzyme, transposase responsible for transposition, the movement by a transposon. ※ They are discovered by Barbara McClintock in the early 1950s. ※ The transposons now exist in all organisms on the earth, including human. ※ ...
ppt
ppt

... So, as something gets larger, the volume increases more than the surface area… and the demand for nutrients (to meet peak productivity) grows faster than the rate at which the more slowly increasing SA can supply them. So, supply fails to meet demand, and the cell cannot meet peak productivity… it b ...
HiPer® Bacterial Conjugation Teaching Kit
HiPer® Bacterial Conjugation Teaching Kit

... as F+) donate their DNA and other “female types” (designated as F-) receive the DNA as shown in Figure 1. Fcells become F+ when they acquire a small amount of DNA. Hence the F factor is called as the Fertility factor. In contemporary microbiology, the donor’s F factors are known to be plasmids which ...
C2005/F2401 `07 -- Lecture 19 -- Last Edited
C2005/F2401 `07 -- Lecture 19 -- Last Edited

... homologous DNA. They carry the same genes, in the same order, in corresponding places (loci), but they do not necessarily carry the same version (allele) of each gene. For example, the gene for eye color is in the same place on both homologs, but the "eye color gene" on a particular chromosome could ...
A novel gene encoding a 54 kDa polypeptide is
A novel gene encoding a 54 kDa polypeptide is

... could grow on propane or butane. This fragment could therefore be used as a probe for detection of such bacteria. A 23 kb fragment having an ORF encoding a polypeptide of 54 kDa was identified by screening a genomic library of Pseudomonas sp. IMT37 with this 49 kb EcoRI fragment. The sequence of t ...
Driscoll Katee Driscoll Dr. Ely Genetics October 20, 2013 Effects of
Driscoll Katee Driscoll Dr. Ely Genetics October 20, 2013 Effects of

... optimal prediction model, which relied on the method of splitting the data (using some of the data as a training set to predict the HTT CAG repeat lengths for the remaining samples that comprised the other set) (Lee et al. 2013). When the model was run, it was found to predict CAG repeat lengths wit ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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