Gene 760 – Problem Set 2 The purpose of this problem set is to
... ANS: Using bedtools, determine and report the following in your answers: The number of MACS H3K27ac and polII peaks called for each cell type at promoters (defined as 1 kb upstream of an annotated transcription start site), exons, and intergenic/intronic regions (potential enhancers). Note: Calli ...
... ANS: Using bedtools, determine and report the following in your answers: The number of MACS H3K27ac and polII peaks called for each cell type at promoters (defined as 1 kb upstream of an annotated transcription start site), exons, and intergenic/intronic regions (potential enhancers). Note: Calli ...
Performance Comparison of Two Gene Set Analysis Methods for
... second-best one [4]. We compared the distribution of gene scores that were calculated based on the best and the second-best p-values using a high-volume scatter plot that represented the local density of points by a false color representation (Fig. 1). One may notice the densely populated points alo ...
... second-best one [4]. We compared the distribution of gene scores that were calculated based on the best and the second-best p-values using a high-volume scatter plot that represented the local density of points by a false color representation (Fig. 1). One may notice the densely populated points alo ...
Investigation of the premelanosome protein
... Re-sequencing of parts of the rabbit PMEL gene and identification of intronic polymorphisms To identify polymorphisms that could be useful to evaluate their possible co-segregation with the black-blue spotted phenotype in the F1 families, fragments of the rabbit PMEL gene including 4 out of 11 exons ...
... Re-sequencing of parts of the rabbit PMEL gene and identification of intronic polymorphisms To identify polymorphisms that could be useful to evaluate their possible co-segregation with the black-blue spotted phenotype in the F1 families, fragments of the rabbit PMEL gene including 4 out of 11 exons ...
PDF bestand - 573. kilobytes
... indication that these recurrences were derived from local MRC. When comparing the genetic profiles of the recurrent and the primary tumors, however, no or only minor differences were observed. All five pairs share an identical TP53 mutation, two share a common MSI pattern, and in all combinations, t ...
... indication that these recurrences were derived from local MRC. When comparing the genetic profiles of the recurrent and the primary tumors, however, no or only minor differences were observed. All five pairs share an identical TP53 mutation, two share a common MSI pattern, and in all combinations, t ...
Preparation of recombinant proteins in milk to improve human and
... recombinant proteins which are also not postranscriptionally modified in an appropriate manner. Interestingly, recent studies established recombinant yeast lines capable of glycosylating proteins in a manner similar to animal cells [30]. Pluricellular organisms, plants and animals are the best candi ...
... recombinant proteins which are also not postranscriptionally modified in an appropriate manner. Interestingly, recent studies established recombinant yeast lines capable of glycosylating proteins in a manner similar to animal cells [30]. Pluricellular organisms, plants and animals are the best candi ...
File
... will have one copy from your mother and one copy from your father. It is possible that one of these copies is associated with high cholesterol levels, while the other is associated with low cholesterol levels. For convenience, scientists have assigned a number to each pair of homologous chromosomes, ...
... will have one copy from your mother and one copy from your father. It is possible that one of these copies is associated with high cholesterol levels, while the other is associated with low cholesterol levels. For convenience, scientists have assigned a number to each pair of homologous chromosomes, ...
Using gene expression to investigate the genetic basis of complex
... Without the burden of chasing a reactive effect, another common approach has been to use this data for determining whether disease variants from GWAS are also responsible for natural variation in human transcript levels. The underlying principle is the following: if one allele is more frequent in ca ...
... Without the burden of chasing a reactive effect, another common approach has been to use this data for determining whether disease variants from GWAS are also responsible for natural variation in human transcript levels. The underlying principle is the following: if one allele is more frequent in ca ...
Friedman N, Linial M, Nachman I, Pe'er D. (2000). Using Bayesian networks to analyze expression data. J Comput Biol. 7, 601-20.
... reactions to external and internal signals. All the cells in an organism carry the same genomic data, yet their protein makeup can be drastically different both temporally and spatially, due to regulation. Protein synthesis is regulated by many mechanisms at its different stages. These include mecha ...
... reactions to external and internal signals. All the cells in an organism carry the same genomic data, yet their protein makeup can be drastically different both temporally and spatially, due to regulation. Protein synthesis is regulated by many mechanisms at its different stages. These include mecha ...
No Origin, No Problem for Yeast DNA Replication
... during each cell cycle. In budding yeast, DNA replication initiates from well-defined origins called autonomously replicating sequences (ARSs), while in multicellular organisms replication it is thought to initiate from broader, less well-defined zones. Interestingly, some recent work has suggested ...
... during each cell cycle. In budding yeast, DNA replication initiates from well-defined origins called autonomously replicating sequences (ARSs), while in multicellular organisms replication it is thought to initiate from broader, less well-defined zones. Interestingly, some recent work has suggested ...
Using Bayesian Networks to Analyze Expression Data
... reactions to external and internal signals. All the cells in an organism carry the same genomic data, yet their protein makeup can be drastically different both temporally and spatially, due to regulation. Protein synthesis is regulated by many mechanisms at its different stages. These include mecha ...
... reactions to external and internal signals. All the cells in an organism carry the same genomic data, yet their protein makeup can be drastically different both temporally and spatially, due to regulation. Protein synthesis is regulated by many mechanisms at its different stages. These include mecha ...
Prophase 1
... Homologous chromosomes pair up Crossing over occurs – pieces of homologous chromosomes switch places Nuclear envelope disappears ...
... Homologous chromosomes pair up Crossing over occurs – pieces of homologous chromosomes switch places Nuclear envelope disappears ...
Mice homozygous for a targeted disruption of Hoxd-3
... the second cervical vertebra, the axis, is also affected. The dens and the superior facets are deleted, and the axis shows ‘atlas-like’ characteristics. An unexpected observation is that different parts of the same vertebra are differentially affected by the loss of Hoxd-3 function. Some parts are d ...
... the second cervical vertebra, the axis, is also affected. The dens and the superior facets are deleted, and the axis shows ‘atlas-like’ characteristics. An unexpected observation is that different parts of the same vertebra are differentially affected by the loss of Hoxd-3 function. Some parts are d ...
Textbook Chapter 2 Answer
... 6. Letters used to represent alleles may vary, but the patterns should be similar to the following sample answers. ...
... 6. Letters used to represent alleles may vary, but the patterns should be similar to the following sample answers. ...
The EGF-CFC Protein One-Eyed Pinhead Is Essential for
... to double mutants for sqt and cyc, two zebrafish nodalrelated genes (Figure 1F). Mutant embryos display severe defects not seen in Zoep mutants, including lack of the notochord, pronephros, and blood. A variable number of somites that form in the tail region are the only nonectodermal structures det ...
... to double mutants for sqt and cyc, two zebrafish nodalrelated genes (Figure 1F). Mutant embryos display severe defects not seen in Zoep mutants, including lack of the notochord, pronephros, and blood. A variable number of somites that form in the tail region are the only nonectodermal structures det ...
Introduction - people.bath.ac.uk
... This phenotype is attributed to a defect specifically in PtdIns(3,5)P2 synthesis from PtdIns(3)P as a point mutant defective in PtdIns5P synthesis shows normal vacuole morphology (Ikonomov et al., 2002). PtdIns(3)P is heavily concentrated on the early and late endosomes consistent with an enlarged ...
... This phenotype is attributed to a defect specifically in PtdIns(3,5)P2 synthesis from PtdIns(3)P as a point mutant defective in PtdIns5P synthesis shows normal vacuole morphology (Ikonomov et al., 2002). PtdIns(3)P is heavily concentrated on the early and late endosomes consistent with an enlarged ...
Male Health Issues - Fred Hutchinson Cancer Research Center
... and the possibility of testosterone deficiency also exists. Radiation therapy can affect testicular function in two ways: Radiation aimed directly at or near the testicles. The sperm-producing cells (germ cells) are very sensitive to the effects of radiation therapy. Most males who receive radiati ...
... and the possibility of testosterone deficiency also exists. Radiation therapy can affect testicular function in two ways: Radiation aimed directly at or near the testicles. The sperm-producing cells (germ cells) are very sensitive to the effects of radiation therapy. Most males who receive radiati ...
Adherin - Semantic Scholar
... in fungi: the rad9-1 adherin mutant of the mushroom Coprinus cinereus is defective in meiotic DNA repair, chromatid cohesin and homolog pairing [1]; mis4 adherin mutants of the fission yeast Schizosaccharomyces pombe display DNA repair and mitotic sister chromatid cohesion defects [2]; and scc2 adhe ...
... in fungi: the rad9-1 adherin mutant of the mushroom Coprinus cinereus is defective in meiotic DNA repair, chromatid cohesin and homolog pairing [1]; mis4 adherin mutants of the fission yeast Schizosaccharomyces pombe display DNA repair and mitotic sister chromatid cohesion defects [2]; and scc2 adhe ...
Developmental, transcriptome, and genetic alterations associated
... absence of regular post-meiotic germline development in CB. RNA-sequencing was also used for genetic variant calling and 14 single-nucleotide polymorphisms distinguishing the CB and PX variant lines were detected. Among these, CB-specific polymorphisms were considered as candidate parthenocarpy-resp ...
... absence of regular post-meiotic germline development in CB. RNA-sequencing was also used for genetic variant calling and 14 single-nucleotide polymorphisms distinguishing the CB and PX variant lines were detected. Among these, CB-specific polymorphisms were considered as candidate parthenocarpy-resp ...
Chapter 21 Extranuclear genes
... mRNA is translated outside the mitochondria on cytosolic ribosomes Synthesized proteins are transported into the mitochondria Complete system is assemble in mitochondrial inner membrane ...
... mRNA is translated outside the mitochondria on cytosolic ribosomes Synthesized proteins are transported into the mitochondria Complete system is assemble in mitochondrial inner membrane ...
S1 Document.
... QuikChange site-directed mutagenesis kit (Agilent Technologies). Primers used for mutagenesis are listed in Table S1. ...
... QuikChange site-directed mutagenesis kit (Agilent Technologies). Primers used for mutagenesis are listed in Table S1. ...
A forkhead-domain gene is mutated in a severe speech and
... sequence of a hypothetical 2.5-kilobase (kb) transcript comprising 17 exons and containing a complete ORF of about 2.1 kb (Fig. 2). We verified the predicted transcript sequence experimentally (see Methods), confirming the exon–intron structure of the gene and identifying alternative splicing of two ...
... sequence of a hypothetical 2.5-kilobase (kb) transcript comprising 17 exons and containing a complete ORF of about 2.1 kb (Fig. 2). We verified the predicted transcript sequence experimentally (see Methods), confirming the exon–intron structure of the gene and identifying alternative splicing of two ...
Cook, Robert. 1937. A chronology of genetics. Yearbook of
... were recognized. Certain of the types depicted on those ancient monuments bear a remarkable resemblance to modern breeds. Excellent types of beef cattle and of merinolike sheep are to be seen in some of these ancient relics, which mark the beginnings of recorded history. Jacob’s famous agreement wit ...
... were recognized. Certain of the types depicted on those ancient monuments bear a remarkable resemblance to modern breeds. Excellent types of beef cattle and of merinolike sheep are to be seen in some of these ancient relics, which mark the beginnings of recorded history. Jacob’s famous agreement wit ...
A Genetical Genomics Project
... • Set of genes G is classified into two groups eg by sex • A given GO annotation term classifies the genes into two groups (present, absent) • The data are a 2x2 contingency table classified by sex and GO, and the test of GO/sex association can be done either by a chi-squared test or by Fisher’s Exa ...
... • Set of genes G is classified into two groups eg by sex • A given GO annotation term classifies the genes into two groups (present, absent) • The data are a 2x2 contingency table classified by sex and GO, and the test of GO/sex association can be done either by a chi-squared test or by Fisher’s Exa ...
All these mutants are being deposited at FGSC (Table... information will be made available to anyone interested in analyzing...
... results from repeats of the same cross, carried out in different laboratories, show very On the other hand, the results summarized in Table 2 are based on large differences. original data from many different crosses which were relatively uniform (hence the small SEM). Furthermore, when crosses are g ...
... results from repeats of the same cross, carried out in different laboratories, show very On the other hand, the results summarized in Table 2 are based on large differences. original data from many different crosses which were relatively uniform (hence the small SEM). Furthermore, when crosses are g ...