Unearthing the Roles of Imprinted Genes in the Placenta
... imprinted status is reported to be conserved also in other species, i.e., cattle [31–34]. As summarized in Table 1, imprinted gene expression can be found in the placenta, the fetus, or both, independently of the parental origin of the expressed allele, and may be widespread or specific to certain ce ...
... imprinted status is reported to be conserved also in other species, i.e., cattle [31–34]. As summarized in Table 1, imprinted gene expression can be found in the placenta, the fetus, or both, independently of the parental origin of the expressed allele, and may be widespread or specific to certain ce ...
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... Prediction of GV interaction effects A microarray experiment is a multi-step process and each step may introduce a potential source of variation. The variation of the measured gene expression data can be generally classified into three generic categories: biological variation, technical variation, a ...
... Prediction of GV interaction effects A microarray experiment is a multi-step process and each step may introduce a potential source of variation. The variation of the measured gene expression data can be generally classified into three generic categories: biological variation, technical variation, a ...
Computational Diagnosis
... When considering all possible linear planes for separating the patient groups, we always find one that perfectly fits, without a biological reason for this. When considering only planes that depend on maximally 20 genes it is not guaranteed that we find a well fitting signature. If in spite of this ...
... When considering all possible linear planes for separating the patient groups, we always find one that perfectly fits, without a biological reason for this. When considering only planes that depend on maximally 20 genes it is not guaranteed that we find a well fitting signature. If in spite of this ...
The Role of TP53 in Cervical Carcinogenesis
... that in the presence of these HPV types the p53 mutations represent a more important event for the development of an invasive cancer. This association can be explained by the fact that E6 proteins from intermediate-risk HPV types may have a reduced activity in targeting p53 in comparison to the high ...
... that in the presence of these HPV types the p53 mutations represent a more important event for the development of an invasive cancer. This association can be explained by the fact that E6 proteins from intermediate-risk HPV types may have a reduced activity in targeting p53 in comparison to the high ...
What is a gene, post-ENCODE? History and updated
... It was the solution of the three-dimensional structure of DNA by Watson and Crick in 1953 (Watson and Crick 1953) that explained how DNA could function as the molecule of heredity. Base pairing explained how genetic information could be copied, and the existence of two strands explained how occasion ...
... It was the solution of the three-dimensional structure of DNA by Watson and Crick in 1953 (Watson and Crick 1953) that explained how DNA could function as the molecule of heredity. Base pairing explained how genetic information could be copied, and the existence of two strands explained how occasion ...
What traits are carried on mobile
... generally decreases under selection (Bouma and Lenski, 1988; Turner et al., 1998); plasmids that exert less of a cost on their hosts have a higher representation in daughter cells. However, as an increase in vertical transfer generally comes at a cost to HGT, there will be an optimum in which gene t ...
... generally decreases under selection (Bouma and Lenski, 1988; Turner et al., 1998); plasmids that exert less of a cost on their hosts have a higher representation in daughter cells. However, as an increase in vertical transfer generally comes at a cost to HGT, there will be an optimum in which gene t ...
Preimplantation genetic diagnosis today
... Analysis of spare human embryos or those rejected for transfer following FISH analysis of the sex chromosomes has confirmed the relatively high incidence of aneuploidy (-25%) at conception (Munne et al., 1993). There also appears to be an unexpectedly marked increase with maternal age. In some studi ...
... Analysis of spare human embryos or those rejected for transfer following FISH analysis of the sex chromosomes has confirmed the relatively high incidence of aneuploidy (-25%) at conception (Munne et al., 1993). There also appears to be an unexpectedly marked increase with maternal age. In some studi ...
U2Word
... TRANSLATION: Protein Synthesis in Cells I. Chapter 5 Gene Expression A. Transcription produces a mRNA that has the “same” base sequence as the corresponding gene(s). Fig 5-22 B. Translation is the process in which the base sequence of the mRNA is used by the ribosome to synthesize a protein (polypep ...
... TRANSLATION: Protein Synthesis in Cells I. Chapter 5 Gene Expression A. Transcription produces a mRNA that has the “same” base sequence as the corresponding gene(s). Fig 5-22 B. Translation is the process in which the base sequence of the mRNA is used by the ribosome to synthesize a protein (polypep ...
Paper - Ran Blekhman
... Furthermore, although sites such as TFBSs can be computationally predicted using evolutionary conservation as a criterion, estimates of the true level of selective constraint (defined as the fraction of strongly deleterious mutations occurring at a locus) in regulatory regions will, by definition, b ...
... Furthermore, although sites such as TFBSs can be computationally predicted using evolutionary conservation as a criterion, estimates of the true level of selective constraint (defined as the fraction of strongly deleterious mutations occurring at a locus) in regulatory regions will, by definition, b ...
The CpG island methylator phenotype (CIMP) in
... (cytosine preceding guanine) islands are regions within the genome that are common in promoter sites rich in CpG dinucleotides. More than 50% of human genes have been found to be regulated in this way, by promoters including CpG islands. Several CpG dinucleotides, which are methylated in normal cell ...
... (cytosine preceding guanine) islands are regions within the genome that are common in promoter sites rich in CpG dinucleotides. More than 50% of human genes have been found to be regulated in this way, by promoters including CpG islands. Several CpG dinucleotides, which are methylated in normal cell ...
Auditory midbrain neurons that count
... interval of just 30 ms completely reset the integration process; after this long interval, eight additional optimal intervals were needed to elicit responses (Fig. 3a, bottom). This 30-ms interval was similar to that seen in the ‘encounter’ calls of this species (Fig. 1a). We defined the reset time ...
... interval of just 30 ms completely reset the integration process; after this long interval, eight additional optimal intervals were needed to elicit responses (Fig. 3a, bottom). This 30-ms interval was similar to that seen in the ‘encounter’ calls of this species (Fig. 1a). We defined the reset time ...
Living Synaptic Vesicle Marker: Synaptotagmin-GFP
... to Leu and Ser 65 to Thr and fluoresces 35-fold more intensely than wild-type GFP when excited at 488 nm, based on spectral analysis of equal amounts of soluble protein (Cormack et al., 1996). Four syt-eGFP transgenic lines were generated; one with insertion on the X chromosome, two on the second ch ...
... to Leu and Ser 65 to Thr and fluoresces 35-fold more intensely than wild-type GFP when excited at 488 nm, based on spectral analysis of equal amounts of soluble protein (Cormack et al., 1996). Four syt-eGFP transgenic lines were generated; one with insertion on the X chromosome, two on the second ch ...
Atopic Dermatitis Foundation Bibliographic news on atopic
... been known that the losses of function mutations are not the only genetic factor of atopic dermatitis. Variation in the number of intragenic copies also involved. Indeed, each exon 3 contains 10, 11, 12 similar repetitive sequences and the shortest genotype (10.10), which increases the risk of AD i ...
... been known that the losses of function mutations are not the only genetic factor of atopic dermatitis. Variation in the number of intragenic copies also involved. Indeed, each exon 3 contains 10, 11, 12 similar repetitive sequences and the shortest genotype (10.10), which increases the risk of AD i ...
Answers questions chapter 14
... mRNA splicing. Specifically, an A residue at the branch point uses its 2′-OH to attack the phosphoryl group of a G at the 5′ splice site. This links the branch site A to the 5′ splice site G, cleaving the phosphodiester linkage at the 5′ splice site and freeing the 3′ end of the (5′) exon. This free ...
... mRNA splicing. Specifically, an A residue at the branch point uses its 2′-OH to attack the phosphoryl group of a G at the 5′ splice site. This links the branch site A to the 5′ splice site G, cleaving the phosphodiester linkage at the 5′ splice site and freeing the 3′ end of the (5′) exon. This free ...
RNA Processing in Eukaryotes
... Other genes in the mitochondrial genome encode 40- to 80-nucleotide guide RNAs. One or more of these molecules interacts by complementary base pairing with some of the nucleotides in the pre-mRNA transcript. However, the guide RNA has more A nucleotides than the pre-mRNA has U nucleotides to bind wi ...
... Other genes in the mitochondrial genome encode 40- to 80-nucleotide guide RNAs. One or more of these molecules interacts by complementary base pairing with some of the nucleotides in the pre-mRNA transcript. However, the guide RNA has more A nucleotides than the pre-mRNA has U nucleotides to bind wi ...
HbF inducers
... been shown to induce HbF synthesis in vitro ● Some studies have been carried out using valproic acid, a compound related to short fatty acid derivatives, reported increased HbF levels ...
... been shown to induce HbF synthesis in vitro ● Some studies have been carried out using valproic acid, a compound related to short fatty acid derivatives, reported increased HbF levels ...
Finding the wheat homologues of genes from model organisms
... be associated with the gene tree. Note that the list presented in the orthologue view is extracted from the gene tree data. Follow the steps below to find to use the orthologue feature of Ensembl. 1. Click on the “Orthologue” link under the Plant Compara tool of the gene-based display. This will pre ...
... be associated with the gene tree. Note that the list presented in the orthologue view is extracted from the gene tree data. Follow the steps below to find to use the orthologue feature of Ensembl. 1. Click on the “Orthologue” link under the Plant Compara tool of the gene-based display. This will pre ...
Measurement of DNA Copy Number at Microsatellite Loci Using
... chromosome 2E has been reported in tumors in F1 crosses of these mice (19, 20). We used QuMA to assess deletions at 27 loci along chromosome 2 using spleen DNA from eight irradiated SJL mice. Six of the eight spleens were comprised mostly of leukemic cells. Fig. 2B shows that these analyses define a ...
... chromosome 2E has been reported in tumors in F1 crosses of these mice (19, 20). We used QuMA to assess deletions at 27 loci along chromosome 2 using spleen DNA from eight irradiated SJL mice. Six of the eight spleens were comprised mostly of leukemic cells. Fig. 2B shows that these analyses define a ...
Meiosis - SP New Moodle
... meiosis 1 have chromosomes and alleles that are different from each other and from the diploid cell that entered meiosis I. ...
... meiosis 1 have chromosomes and alleles that are different from each other and from the diploid cell that entered meiosis I. ...
L`utilizzo di probiotici ed immunostimolanti in acquacoltura può
... gilthead sea bream larvae until day 75 post hatch. The control group was fed with a standard diet based on rotifers and Artemia nauplia, in the group 1 the Bacillus mixture was supplied via live prey, while in the group 2, probiotics were delivered through live prey and with addition to rearing wate ...
... gilthead sea bream larvae until day 75 post hatch. The control group was fed with a standard diet based on rotifers and Artemia nauplia, in the group 1 the Bacillus mixture was supplied via live prey, while in the group 2, probiotics were delivered through live prey and with addition to rearing wate ...
1030examII
... The products of fertilization would have the same number of chromosomes as their parents The products of fertilization would have more chromosomes than their parents The products of fertilization would have fewer chromosomes than their parents Fertilization could not occur None of the above are corr ...
... The products of fertilization would have the same number of chromosomes as their parents The products of fertilization would have more chromosomes than their parents The products of fertilization would have fewer chromosomes than their parents Fertilization could not occur None of the above are corr ...
Floral organ identity genes in the orchid
... DcOAP3B, DcOPI, DcOAG1, DcOAG2 and DcOSEP1 (GenBank accession numbers DQ119837, DQ119838, DQ119839, DQ119840, DQ119841, DQ119842 and DQ119843, respectively). DcOAP2 cDNA is 1711 bp long with a 1338-bp coding region (Figure S1). Similar to the known AP2-like genes, the predicted amino acid sequence o ...
... DcOAP3B, DcOPI, DcOAG1, DcOAG2 and DcOSEP1 (GenBank accession numbers DQ119837, DQ119838, DQ119839, DQ119840, DQ119841, DQ119842 and DQ119843, respectively). DcOAP2 cDNA is 1711 bp long with a 1338-bp coding region (Figure S1). Similar to the known AP2-like genes, the predicted amino acid sequence o ...
cancer phenotype in selected families are a feature of the inherited
... likelihood that these genes may be susceptible to inactivation by homologous recombination.6 The first rearrangement described in BRCA1 was a 1 kb deletion that included the loss of exon 17.7 Since that time, up to 30 different genomic rearrangements, both deletions and duplications, ranging in size ...
... likelihood that these genes may be susceptible to inactivation by homologous recombination.6 The first rearrangement described in BRCA1 was a 1 kb deletion that included the loss of exon 17.7 Since that time, up to 30 different genomic rearrangements, both deletions and duplications, ranging in size ...