Mutation and selection within the individual
... changes in B cells essential to acquired immunity to disease (French, Laskov & Scharff, 1989). Mosaicism is more difficult to see within the germline of animals, although it undoubtedly occurs. We can, however, infer its existence using a number of lines of evidence. Firstly, de novo mutations that ...
... changes in B cells essential to acquired immunity to disease (French, Laskov & Scharff, 1989). Mosaicism is more difficult to see within the germline of animals, although it undoubtedly occurs. We can, however, infer its existence using a number of lines of evidence. Firstly, de novo mutations that ...
The PEG13-DMR and brain-specific enhancers dictate imprinted
... conformation capture (3C) we show the reciprocal expression of the novel, paternally expressed, PEG13 non-coding RNA and maternally expressed KCNK9 genes in brain, and the biallelic expression of flanking transcripts in a range of tissues. We identify a tandem-repeat region overlapping the PEG13 tra ...
... conformation capture (3C) we show the reciprocal expression of the novel, paternally expressed, PEG13 non-coding RNA and maternally expressed KCNK9 genes in brain, and the biallelic expression of flanking transcripts in a range of tissues. We identify a tandem-repeat region overlapping the PEG13 tra ...
Phenotypic comparison between maternal and
... (B-C) The posterior group: A11 (B, maternal phenotype) or most (C, zygotic phenotype) abdominal segments are deleted. (B) Embryo derived from female mutant for nosLT . (C) Embryo homozygous mutant fot kniIIIE4s . (D,E) The terminal group: Embryos in D (maternal phenotype) and E (tygotic phenotype) l ...
... (B-C) The posterior group: A11 (B, maternal phenotype) or most (C, zygotic phenotype) abdominal segments are deleted. (B) Embryo derived from female mutant for nosLT . (C) Embryo homozygous mutant fot kniIIIE4s . (D,E) The terminal group: Embryos in D (maternal phenotype) and E (tygotic phenotype) l ...
ppt
... – Homologous chromosomes come together as pairs by synapsis – Each pair, with four chromatids, is called a tetrad – Nonsister chromatids exchange genetic material by crossing over ...
... – Homologous chromosomes come together as pairs by synapsis – Each pair, with four chromatids, is called a tetrad – Nonsister chromatids exchange genetic material by crossing over ...
This article appeared in a journal published by Elsevier. The
... by these DNA vaccines through intramuscular immunization. The IgG subclass (IgG1 and IgG2a) analysis indicates that divalent DNA vaccine induces both Th1 and Th2 immune responses. The protective efficacy was evaluated by the survival against lethal challenge with A. pleuropneumoniae serotype 1. The g ...
... by these DNA vaccines through intramuscular immunization. The IgG subclass (IgG1 and IgG2a) analysis indicates that divalent DNA vaccine induces both Th1 and Th2 immune responses. The protective efficacy was evaluated by the survival against lethal challenge with A. pleuropneumoniae serotype 1. The g ...
RELATIONSHIPS BETWEEN HEMATOLOGICAL PARAMETERS AND GLOBIN TYPES IN GENTILE DI PUGLIA OVINE BREED
... The effect of genotypes at globin systems on hematological data was evaluated on 289 Gentile di Puglia animals. A significant effect was detected for β-globin locus on hematocrit (HCT) and mean corpuscolar volume (MCV), with decreasing HCT and MCV for decreasing number of βA alleles in the genotype. ...
... The effect of genotypes at globin systems on hematological data was evaluated on 289 Gentile di Puglia animals. A significant effect was detected for β-globin locus on hematocrit (HCT) and mean corpuscolar volume (MCV), with decreasing HCT and MCV for decreasing number of βA alleles in the genotype. ...
Precision Medicine Initiative and Cancer Research
... NCI Immunology and Immunotherapy Research: As NCI identifies the potential of tumors to alter their genetic code and generate potent antigens, immunotherapy is becoming an integral part of precision medicine. NCI continues to support many extramural grantees and intramural investigators who are work ...
... NCI Immunology and Immunotherapy Research: As NCI identifies the potential of tumors to alter their genetic code and generate potent antigens, immunotherapy is becoming an integral part of precision medicine. NCI continues to support many extramural grantees and intramural investigators who are work ...
A Tree of Life Based on Protein Domain Organizations
... et al. 1999; Lin and Gerstein 2000; Caetano-Anolles G and Caetano-Anolles D 2003; Winstanley et al. 2005; Yang et al. 2005), we supposed that the Pfam domains were more suitable to the present study for the following 2 reasons. First, the Pfam domains are defined by sequence conservation and have cl ...
... et al. 1999; Lin and Gerstein 2000; Caetano-Anolles G and Caetano-Anolles D 2003; Winstanley et al. 2005; Yang et al. 2005), we supposed that the Pfam domains were more suitable to the present study for the following 2 reasons. First, the Pfam domains are defined by sequence conservation and have cl ...
Ehlers-Danlos syndrome type VIIA and VIIB result from splice
... To identify the mutations in these seven cell strains, we reverse transcribed RNA. Then, by using the polymerase chain reaction, we amplified the regions surrounding exon 6 of either the COL1A2 or the COL1A1 cDNA. In cells from the index case in family A, amplification around exon 6 in the proa2(I) ...
... To identify the mutations in these seven cell strains, we reverse transcribed RNA. Then, by using the polymerase chain reaction, we amplified the regions surrounding exon 6 of either the COL1A2 or the COL1A1 cDNA. In cells from the index case in family A, amplification around exon 6 in the proa2(I) ...
Text S1: Genome-Wide High-Resolution Mapping of UV
... text, crossovers occurring between the homologs in the CEN12-HYG, HYG-TRP1, and TRP1URA3 intervals could be identified unambiguously by their patterns of marker segregation within the sectors. In addition to crossovers (Figure 7), we also found UV-induced BIR events (Figure S3) and intrachromatid r ...
... text, crossovers occurring between the homologs in the CEN12-HYG, HYG-TRP1, and TRP1URA3 intervals could be identified unambiguously by their patterns of marker segregation within the sectors. In addition to crossovers (Figure 7), we also found UV-induced BIR events (Figure S3) and intrachromatid r ...
Origin of New Genes: Evidence from Experimental
... jingwei acquire start codons and an appropriate regulatory system? Molecular analyses showed that the retroposed Adh sequences recruited three nearby exons containing an in-frame start codon (Figure 1), yielding a chimerical protein. The regulatory sequence associated with the acquired exon was also ...
... jingwei acquire start codons and an appropriate regulatory system? Molecular analyses showed that the retroposed Adh sequences recruited three nearby exons containing an in-frame start codon (Figure 1), yielding a chimerical protein. The regulatory sequence associated with the acquired exon was also ...
3. Chromosome Defects
... caused by misrepair of broken chromosomes, improper recombination, or improper segregation of chromosomes during mitosis or meiosis Chromosome abnormalities can affect Germ cell (constitutional) Somatic cell 1. Variation in chromosome number polyploidy: extra sets of chromosomes 1-3% of huma ...
... caused by misrepair of broken chromosomes, improper recombination, or improper segregation of chromosomes during mitosis or meiosis Chromosome abnormalities can affect Germ cell (constitutional) Somatic cell 1. Variation in chromosome number polyploidy: extra sets of chromosomes 1-3% of huma ...
3. Chromosome Defects
... caused by misrepair of broken chromosomes, improper recombination, or improper segregation of chromosomes during mitosis or meiosis Chromosome abnormalities can affect Germ cell (constitutional) Somatic cell 1. Variation in chromosome number polyploidy: extra sets of chromosomes 1-3% of huma ...
... caused by misrepair of broken chromosomes, improper recombination, or improper segregation of chromosomes during mitosis or meiosis Chromosome abnormalities can affect Germ cell (constitutional) Somatic cell 1. Variation in chromosome number polyploidy: extra sets of chromosomes 1-3% of huma ...
A Novel Chimeric Low-Molecular-Weight Glutenin
... glutamine-rich region as shown in Figure 2. Furthermore, large fragment deletions and substitutions presented in the AkjLMW-i gene were similar to LMW-mtype genes in III, IV, and V domains. Therefore, the cloned AkjLMW-i gene was a novel chimeric gene, which possessed characteristics of both LMW-i ( ...
... glutamine-rich region as shown in Figure 2. Furthermore, large fragment deletions and substitutions presented in the AkjLMW-i gene were similar to LMW-mtype genes in III, IV, and V domains. Therefore, the cloned AkjLMW-i gene was a novel chimeric gene, which possessed characteristics of both LMW-i ( ...
A Customized Gene Expression Microarray
... compared with their parental lines Ohichi and Shiroseto. A custom-designed microarray, based on long oligonucleotide technology and including genes involved in cell wall metabolism, revealed that transcript levels of very few genes were altered in the elongation zone of stem internodes, but these in ...
... compared with their parental lines Ohichi and Shiroseto. A custom-designed microarray, based on long oligonucleotide technology and including genes involved in cell wall metabolism, revealed that transcript levels of very few genes were altered in the elongation zone of stem internodes, but these in ...
Cryptochrome 1 controls tomato development
... All seedlings show a signal at approximately the same apparent molecular mass as Arabidopsis CRY1. The less intense signal observed in tomato could be due to the lower absolute levels of cryptochrome, or to the fact that we used an antibody made to the Arabidopsis protein which does not cross-react ...
... All seedlings show a signal at approximately the same apparent molecular mass as Arabidopsis CRY1. The less intense signal observed in tomato could be due to the lower absolute levels of cryptochrome, or to the fact that we used an antibody made to the Arabidopsis protein which does not cross-react ...
HighFour Biology Round 8 Category D: Grades 11 – 12 Friday, April
... High-density lipoprotein or HDL is a particle in the blood that is made up of several cholesterol molecules and other lipids bound to a protein. HDL scavenges excess cholesterol and returns it to the liver. Individuals with high ratio of LDL to HDL are more at risk for heart disease. ...
... High-density lipoprotein or HDL is a particle in the blood that is made up of several cholesterol molecules and other lipids bound to a protein. HDL scavenges excess cholesterol and returns it to the liver. Individuals with high ratio of LDL to HDL are more at risk for heart disease. ...
10 book ppt adapted 2011
... • How this potential is achieved depends partly on the interaction of the gene with other genes. But it also depends partly on the environment. • For example, a person may have a genetic tendency toward being overweight. But the person's actual weight will depend on such environmental factors as how ...
... • How this potential is achieved depends partly on the interaction of the gene with other genes. But it also depends partly on the environment. • For example, a person may have a genetic tendency toward being overweight. But the person's actual weight will depend on such environmental factors as how ...
PDF - Molecular Vision
... phenotypes are demonstrated in Figure 1 and Figure 2. IVCM in all patients demonstrated abnormal endothelial appearances (Figure 2 and Figure 3). Vesicular PPCD lesions appeared as focal circular or elliptical regions with hyporeflective centers and scalloped borders. These lesions were often surrou ...
... phenotypes are demonstrated in Figure 1 and Figure 2. IVCM in all patients demonstrated abnormal endothelial appearances (Figure 2 and Figure 3). Vesicular PPCD lesions appeared as focal circular or elliptical regions with hyporeflective centers and scalloped borders. These lesions were often surrou ...
Physical Mapping of Important Trait Loci in the Pig
... genetics of traits, such as growth, reproduction, disease resistance and production. This study has been focused on physical mapping of important trait loci in the pig. The different physical mapping techniques are powerful to construct restriction maps, reveal syntenic groups of genes and to determ ...
... genetics of traits, such as growth, reproduction, disease resistance and production. This study has been focused on physical mapping of important trait loci in the pig. The different physical mapping techniques are powerful to construct restriction maps, reveal syntenic groups of genes and to determ ...
Instructional Unit: Biology Q1
... A Science Odyssey: DNA workshop- You Try It www.pbs.org/wgbh/aso/tryit/dna/index-nojs.html McGraw Hill: Biological Concepts & Connections; Interactivity that includes a review of protein synthesis through matching and a 2nd section that allows students to build a protein: www.mhhe.com/socscience/ant ...
... A Science Odyssey: DNA workshop- You Try It www.pbs.org/wgbh/aso/tryit/dna/index-nojs.html McGraw Hill: Biological Concepts & Connections; Interactivity that includes a review of protein synthesis through matching and a 2nd section that allows students to build a protein: www.mhhe.com/socscience/ant ...
Mutations in the MicroRNA Complementarity Site
... ICU4 gene, which we previously mapped to chromosome 1 between the T27K12-Sp6 and nga128 microsatellite markers (Serrano-Cartagena et al., 2000). The genotyping of 130 icu4-1 homozygotes selected from an F2 mapping population derived from a Columbia-0 (Col-0) 3 icu4-1/icu4-1 cross allowed us to narro ...
... ICU4 gene, which we previously mapped to chromosome 1 between the T27K12-Sp6 and nga128 microsatellite markers (Serrano-Cartagena et al., 2000). The genotyping of 130 icu4-1 homozygotes selected from an F2 mapping population derived from a Columbia-0 (Col-0) 3 icu4-1/icu4-1 cross allowed us to narro ...
4.11 Repro Biol 053 Reik NEW
... tissues throughout development. This means that the alleles retain a memory of their parental origin. In molecular terms, imprinted genes acquire different marks in the sperm and egg, and these marks must be heritable through subsequent cell divisions2,3. Part of the marking is DNA methylation — the ...
... tissues throughout development. This means that the alleles retain a memory of their parental origin. In molecular terms, imprinted genes acquire different marks in the sperm and egg, and these marks must be heritable through subsequent cell divisions2,3. Part of the marking is DNA methylation — the ...