Analysis of aptamer sequence activity relationshipsw
... as evidenced by NMR7 and crystallographic structural studies8 (see Fig. 1). This is not only of interest because it highlights the complex interplay between nucleic acid structure and binding affinity, but such structures offer biological significance, as the formation of G-quadruplexes within genomic D ...
... as evidenced by NMR7 and crystallographic structural studies8 (see Fig. 1). This is not only of interest because it highlights the complex interplay between nucleic acid structure and binding affinity, but such structures offer biological significance, as the formation of G-quadruplexes within genomic D ...
NItric Oxide and Prostaglandins: Mediators of Pathogenesis in
... • Thalassemias are defects in synthesis of either a- or bglobin chains of hemoglobin (hemoglobin adult = a2b2) ...
... • Thalassemias are defects in synthesis of either a- or bglobin chains of hemoglobin (hemoglobin adult = a2b2) ...
High Frequency of Recombination (Hfr)
... Hfr DNA that is not incorporated in the F- strand, and DNA that has crossed out of the F- strand is ...
... Hfr DNA that is not incorporated in the F- strand, and DNA that has crossed out of the F- strand is ...
Auxin signals — turning genes on and turning cells around
... Key to our present understanding of auxin-controlled gene expression are transcripts that are rapidly induced by auxin, which are collectively referred to as primary auxin-response genes [4]. In Arabidopsis, these include several families of well-characterized genes [5], including many of the 29 mem ...
... Key to our present understanding of auxin-controlled gene expression are transcripts that are rapidly induced by auxin, which are collectively referred to as primary auxin-response genes [4]. In Arabidopsis, these include several families of well-characterized genes [5], including many of the 29 mem ...
Construction and Characterization of a Highly Regulable Expression
... A number of different expression vectors have been developed to facilitate the regulated overproduction of proteins in Escherichia coli and related bacteria. Some of the more popular ones include pKK223-3, pKK233-2, pTrc99A, and the pET family of expression vectors. These vectors were designed to be ...
... A number of different expression vectors have been developed to facilitate the regulated overproduction of proteins in Escherichia coli and related bacteria. Some of the more popular ones include pKK223-3, pKK233-2, pTrc99A, and the pET family of expression vectors. These vectors were designed to be ...
Nucleotide Sequence Preservation of Human
... sequence comparisons of the D-loop region of unrelated normal humans (5, 21). Three additional between-individual differences outside the Dloop region of mtDNA were identified in this study. Substitution of cytidine for thymidine at L-strand positions 9698 and 9725 was found in all clones containing ...
... sequence comparisons of the D-loop region of unrelated normal humans (5, 21). Three additional between-individual differences outside the Dloop region of mtDNA were identified in this study. Substitution of cytidine for thymidine at L-strand positions 9698 and 9725 was found in all clones containing ...
Gametogenesis and Fertilization
... capacitation primes sperm for fertilization and includes removal of some components from sperm surface. • After capacitation, hyaluronidase on the sperm head is exposed and breaks down the hyaluronic acid cementing the follicle cells of corona radiata (which surround the egg) together allows spe ...
... capacitation primes sperm for fertilization and includes removal of some components from sperm surface. • After capacitation, hyaluronidase on the sperm head is exposed and breaks down the hyaluronic acid cementing the follicle cells of corona radiata (which surround the egg) together allows spe ...
The human autosomal gene DAZLA: testis
... proteins contain only one copy of the DAZ repeat (nt 725–796), in contrast to the DAZ proteins which contain seven or more DAZ repeats (8,11; unpublished data). In addition, both DAZLA and Dazla contain a 130 bp segment (nt 832–961) at the 3′ portion of the coding region that is absent in DAZ. The p ...
... proteins contain only one copy of the DAZ repeat (nt 725–796), in contrast to the DAZ proteins which contain seven or more DAZ repeats (8,11; unpublished data). In addition, both DAZLA and Dazla contain a 130 bp segment (nt 832–961) at the 3′ portion of the coding region that is absent in DAZ. The p ...
Large Sex Differences in Chicken Behavior and Differences in Promoter DNA-Methylation
... There was a large overlap of the significantly DE genes between the breeds (Figure 2C), but most autosomal genes were only DE in one of the two breeds (Figure 2A, B and D), leaving only one autosomal gene verified in the overlap: the zinc finger RNA binding protein (ZFR) on chromosome 1 (Figure 3D). ...
... There was a large overlap of the significantly DE genes between the breeds (Figure 2C), but most autosomal genes were only DE in one of the two breeds (Figure 2A, B and D), leaving only one autosomal gene verified in the overlap: the zinc finger RNA binding protein (ZFR) on chromosome 1 (Figure 3D). ...
Genetics 3 – Aneuploidies and Other Chromosome
... • Overall incidence at birth is approx 1 in 650 to 1 in 700 • Strong association between incidence and advancing maternal age:20 years, 1 in 1500; 30 years, 1 in 900 40 years, 1 in 100; 45 years, 1 in 30 There are 3 possible causes for Down’s syndrome: ...
... • Overall incidence at birth is approx 1 in 650 to 1 in 700 • Strong association between incidence and advancing maternal age:20 years, 1 in 1500; 30 years, 1 in 900 40 years, 1 in 100; 45 years, 1 in 30 There are 3 possible causes for Down’s syndrome: ...
Gene Conversion in Human Genetic Disease
... abolished, with attendant consequences for the genetic variability manifested by the sequences in question [6]. Figure 1. Mutational models of homologous recombination. In the models of gene conversion, NAHR (non-allelic homologous recombination) and BIR (break-induced replication), the invading str ...
... abolished, with attendant consequences for the genetic variability manifested by the sequences in question [6]. Figure 1. Mutational models of homologous recombination. In the models of gene conversion, NAHR (non-allelic homologous recombination) and BIR (break-induced replication), the invading str ...
Noise in transcription negative feedback loops
... come from plasmid variation and therefore that negative feedback loops play an important role in suppressing both external and internal noise. An important observation is that DG expression without negative feedback exhibits bimodality at intermediate TF repression values. This bimodal behaviour see ...
... come from plasmid variation and therefore that negative feedback loops play an important role in suppressing both external and internal noise. An important observation is that DG expression without negative feedback exhibits bimodality at intermediate TF repression values. This bimodal behaviour see ...
Section D - Prokaryotic and Eukaryotic Chromosome Structure
... • Some genes contain terminator sequences requiring an accessory factor, the rho protein (ρ) to mediated transcription termination. • Rho binds to specific sites in the singlestranded RNA. • Rho protein (hexameric protein) binds to certain RNA structure (72bp) • Rho hydrolyses ATP and moves along th ...
... • Some genes contain terminator sequences requiring an accessory factor, the rho protein (ρ) to mediated transcription termination. • Rho binds to specific sites in the singlestranded RNA. • Rho protein (hexameric protein) binds to certain RNA structure (72bp) • Rho hydrolyses ATP and moves along th ...
CHAPTER 2 - ESSENTIALS OF HUMAN DEVELOPMENT
... Environmental Influences and Contexts 2.64. Research suggests that a portion of intelligence is inherited. What percentage of an individual’s intelligence is generally believed to be due to genetics? a. 10% or less c. around 75% b. around 50% d. over 90% b, factual, medium, p. 62 2.65. Three-year-ol ...
... Environmental Influences and Contexts 2.64. Research suggests that a portion of intelligence is inherited. What percentage of an individual’s intelligence is generally believed to be due to genetics? a. 10% or less c. around 75% b. around 50% d. over 90% b, factual, medium, p. 62 2.65. Three-year-ol ...
Document
... process, changes in gene expression between conditions or over time can be observed. ...
... process, changes in gene expression between conditions or over time can be observed. ...
Clustering Time-Course Gene
... – 18 equally spaced time-points – Of 6300 genes nearly 800 were categorized as cellcycle regulated – A subset of 433 genes with no missing values is a commonly used data set in papers detailing new timecourse methods – Original and follow-up papers clustered genes using Kmeans and hierarchical clust ...
... – 18 equally spaced time-points – Of 6300 genes nearly 800 were categorized as cellcycle regulated – A subset of 433 genes with no missing values is a commonly used data set in papers detailing new timecourse methods – Original and follow-up papers clustered genes using Kmeans and hierarchical clust ...
Differential roles of TGIF family genes in mammalian reproduction Open Access
... conserved downstream and upstream genes in most of species. Human genomic sequence encompassing MYOM1 (partial sequence and not shown)-TGIF1-DLGAP1 (chr18: 3,395,327-3,507,935) compared to the mouse (chr17: 71,147,775-71,255,269), opossum (chr3: 269,037,689269,144,991), platypus (Contig3116: 1-55,20 ...
... conserved downstream and upstream genes in most of species. Human genomic sequence encompassing MYOM1 (partial sequence and not shown)-TGIF1-DLGAP1 (chr18: 3,395,327-3,507,935) compared to the mouse (chr17: 71,147,775-71,255,269), opossum (chr3: 269,037,689269,144,991), platypus (Contig3116: 1-55,20 ...
Ectopic induction and reorganization of Wnt-1
... 3380 L. Bally-Cuif and M. Wassef These studies on mutant mice (McMahon et al., 1992) have also identified En-1 as a gene whose early maintenance of expression in mesencephalon was dependent on Wnt-1; but later-occurring regulatory interactions in met-mesencephalon could not be studied since the who ...
... 3380 L. Bally-Cuif and M. Wassef These studies on mutant mice (McMahon et al., 1992) have also identified En-1 as a gene whose early maintenance of expression in mesencephalon was dependent on Wnt-1; but later-occurring regulatory interactions in met-mesencephalon could not be studied since the who ...
Genetic Insights Into Comparative Morphology
... al., 1995; Suemori et al., 1995). Consistent results have also been obtained by the retinoic acid-induced respecification of vertebrae, which is roughly associated with the shift of the Hox code in the provertebrae (Kessel and Gruss, 1991; Kessel, 1992). It has been shown recently that multiple disr ...
... al., 1995; Suemori et al., 1995). Consistent results have also been obtained by the retinoic acid-induced respecification of vertebrae, which is roughly associated with the shift of the Hox code in the provertebrae (Kessel and Gruss, 1991; Kessel, 1992). It has been shown recently that multiple disr ...
Cloning and characterisation of a cysteine proteinase gene
... In order to clone a complete copy of Llacys1 gene, a cDNA library from L. (L.) amazonensis amastigotes was constructed in lZipLox vector and screened with Llacys1 gene as a probe. Two clones were isolated and sequenced, one of 1.6 kb (2A1) and another of 2.4 kb (3A4). They showed an ORF encoding cys ...
... In order to clone a complete copy of Llacys1 gene, a cDNA library from L. (L.) amazonensis amastigotes was constructed in lZipLox vector and screened with Llacys1 gene as a probe. Two clones were isolated and sequenced, one of 1.6 kb (2A1) and another of 2.4 kb (3A4). They showed an ORF encoding cys ...
Expanding Yeast Knowledge Online.
... names and contact information to the list of colleagues at SGD, where this list can be browsed and searched. Community information such as yeast meetings are announced on the SGD page, and a ‘Virtual Yeast Library’ that contains hyperlinks to other useful yeast web pages is also provided. The genome ...
... names and contact information to the list of colleagues at SGD, where this list can be browsed and searched. Community information such as yeast meetings are announced on the SGD page, and a ‘Virtual Yeast Library’ that contains hyperlinks to other useful yeast web pages is also provided. The genome ...
An In Silico Investigation Into the Discovery of Novel Cis
... Several potential cis-regulatory motifs were identified in this investigation and one in particular that was common to both PAX7 and PAX3 and also to NF1, could have implications for the role of PAX7 in Alveolar Rhabdomyosarcoma and may be the cornerstone to more exciting, unique scientific investig ...
... Several potential cis-regulatory motifs were identified in this investigation and one in particular that was common to both PAX7 and PAX3 and also to NF1, could have implications for the role of PAX7 in Alveolar Rhabdomyosarcoma and may be the cornerstone to more exciting, unique scientific investig ...
