Distortion of quantitative genomic and expression
... QPCR and data analysis were performed using the Chromo4 QPCR system (BioRad Laboratories, Hercules, CA). Primers and amplified intervals were verified for unique genomic representation using BLAT (17) and WU-BLAST (Table 2). Each 50 ml reaction contained 0.5 mM of each primer, 50 ng Cot-1 template o ...
... QPCR and data analysis were performed using the Chromo4 QPCR system (BioRad Laboratories, Hercules, CA). Primers and amplified intervals were verified for unique genomic representation using BLAT (17) and WU-BLAST (Table 2). Each 50 ml reaction contained 0.5 mM of each primer, 50 ng Cot-1 template o ...
Genome-wide histone modification patterns in
... more phylogenetically restricted. Most notably, two major repressive marks are not found in the budding yeast S. cerevisiae. The polycomb-associated modification H3K27me3 is widespread in multicellular organisms, where it plays a key role in control of cell state inheritance (SCHUETTENGRUBER et al. ...
... more phylogenetically restricted. Most notably, two major repressive marks are not found in the budding yeast S. cerevisiae. The polycomb-associated modification H3K27me3 is widespread in multicellular organisms, where it plays a key role in control of cell state inheritance (SCHUETTENGRUBER et al. ...
Word file (68 KB )
... Drosophila cdk7ts1 mutants shows cell cycle but no transcription defects Cdk7 1. cdk7ts1 flies are fully viable at the permissive temperature (18C) and exhibit complete lethality at the restrictive temperature (27C). Between 25C and 26C a small proportion of the cdk7ts1 flies survive. Conditions ...
... Drosophila cdk7ts1 mutants shows cell cycle but no transcription defects Cdk7 1. cdk7ts1 flies are fully viable at the permissive temperature (18C) and exhibit complete lethality at the restrictive temperature (27C). Between 25C and 26C a small proportion of the cdk7ts1 flies survive. Conditions ...
Chronodisruption, cell cycle checkpoints and DNA repair
... (IARC) classified "shift work that involves circadian disruption" as possibly carcinogenic40. In the past few years, there have been numerous supportive meta-analyses and evidence showing that night work does play a role in breast cancer42,43. However, there are no clear indications for the exact pa ...
... (IARC) classified "shift work that involves circadian disruption" as possibly carcinogenic40. In the past few years, there have been numerous supportive meta-analyses and evidence showing that night work does play a role in breast cancer42,43. However, there are no clear indications for the exact pa ...
Genetic polymorphisms of vein wall remodeling in chronic venous
... in the maintenance of vessel wall integrity. Increased expression of VEGF-A or its receptor R2 leads to increased activation of nitric oxide synthase, which then leads to vessel wall damage mediated by oxygen free radicals as well as decreased vessel tone that predisposes to venous stasis.20 VEGF al ...
... in the maintenance of vessel wall integrity. Increased expression of VEGF-A or its receptor R2 leads to increased activation of nitric oxide synthase, which then leads to vessel wall damage mediated by oxygen free radicals as well as decreased vessel tone that predisposes to venous stasis.20 VEGF al ...
Hemoglobin - Wikispaces
... • Each subunit has stretches of a-helical structure & a heme binding pocket. ...
... • Each subunit has stretches of a-helical structure & a heme binding pocket. ...
PDF + SI - Biology Open - The Company of Biologists
... two adjacent markers in the same region was 1.00:0.23:1.00:0.23:1.07. The heterogeneity of genetic and physical distances of these markers revealed that there may be some large chromosome variations between parent materials used in this study and ‘Chiifu-401’ in this 0.46 cM region (Table 2). 4. Dis ...
... two adjacent markers in the same region was 1.00:0.23:1.00:0.23:1.07. The heterogeneity of genetic and physical distances of these markers revealed that there may be some large chromosome variations between parent materials used in this study and ‘Chiifu-401’ in this 0.46 cM region (Table 2). 4. Dis ...
Environmental Pollution
... The characterization of prokaryotic life in hypersaline environments has recently been a centre of interest in microbial ecology (Oren, 2002; Øvreås et al., 2003) and has revealed a high diversity of organisms from various taxonomic affiliations (see Section 4). It has, however, not yet been examin ...
... The characterization of prokaryotic life in hypersaline environments has recently been a centre of interest in microbial ecology (Oren, 2002; Øvreås et al., 2003) and has revealed a high diversity of organisms from various taxonomic affiliations (see Section 4). It has, however, not yet been examin ...
WGCNA: an R package for weighted correlation network analysis
... use functional enrichment and gene ontology information. Overview of functions included in the WGCNA package The WGCNA package contains a comprehensive set of functions for performing a correlation network analysis of large, high-dimensional data sets. Functions in the WGCNA package can be divided i ...
... use functional enrichment and gene ontology information. Overview of functions included in the WGCNA package The WGCNA package contains a comprehensive set of functions for performing a correlation network analysis of large, high-dimensional data sets. Functions in the WGCNA package can be divided i ...
j - Computer Science & Engineering
... – Mutations at the single character level are frequent. – Does anybody know what these are called? makes it difficult to determine evolutionary relationship at the DNA sequence level. – Large gaps occur less frequently. gap features can be used to recognize similarity over long periods of time. ...
... – Mutations at the single character level are frequent. – Does anybody know what these are called? makes it difficult to determine evolutionary relationship at the DNA sequence level. – Large gaps occur less frequently. gap features can be used to recognize similarity over long periods of time. ...
What is the Gene Trying to Do?
... It is therefore appropriate, in considering the validity of the FTNS as a theorem, to consider the assumptions upon which it is based. These are either explicit or implicit in the development below. Among other simplifications, the theorem ignores the existence of two sexes and assumes that the fitnes ...
... It is therefore appropriate, in considering the validity of the FTNS as a theorem, to consider the assumptions upon which it is based. These are either explicit or implicit in the development below. Among other simplifications, the theorem ignores the existence of two sexes and assumes that the fitnes ...
The Mutant of sll1961, Which Encodes a Putative
... Copyright © 2005 American Society of Plant Biologists. All rights reserved. ...
... Copyright © 2005 American Society of Plant Biologists. All rights reserved. ...
Read the Nobel Lecture
... First we needed an assay – a way to detect if telomere elongation was happening. The first assay we tried explored whether a piece of DNA that included a telomere would incorporate DNA precursors more readily than a piece of DNA containing non-telomeric sequences. The idea was that if there was an ...
... First we needed an assay – a way to detect if telomere elongation was happening. The first assay we tried explored whether a piece of DNA that included a telomere would incorporate DNA precursors more readily than a piece of DNA containing non-telomeric sequences. The idea was that if there was an ...
Physiological characterization of natural transformation in
... 1986). As more and more details of natural transformation in a number of these bacteria have been elucidated, it is becoming clear that distinct differences exist in this process between these organisms. Wellknown examples are the sequence specificity of DNA uptake in Haemophilus (Goodgal, 1982) and ...
... 1986). As more and more details of natural transformation in a number of these bacteria have been elucidated, it is becoming clear that distinct differences exist in this process between these organisms. Wellknown examples are the sequence specificity of DNA uptake in Haemophilus (Goodgal, 1982) and ...
Gene transfer in bacteria - McGraw Hill Higher Education
... Most are crucial to maintenance of earth's environment • Release oxygen to atmosphere • Recycle carbon, nitrogen, and other elements • Digest human and other animal waste • Neutralize pesticides and other pollutants • Produce vitamins and other materials essential to humans and other organisms Copyr ...
... Most are crucial to maintenance of earth's environment • Release oxygen to atmosphere • Recycle carbon, nitrogen, and other elements • Digest human and other animal waste • Neutralize pesticides and other pollutants • Produce vitamins and other materials essential to humans and other organisms Copyr ...
this PDF file - E-Journal Faculty of Medicine Universitas
... In the homozygous state there is a decrease in enzyme functions up to 60%. Meanwhile, in heterozygotes, the decrease is only about 30%. MTHFR C677T polymorphism gene may alter folate metabolism and low folate intake may result in increased levels of homocysteine. This may lead to a decrease in DNA m ...
... In the homozygous state there is a decrease in enzyme functions up to 60%. Meanwhile, in heterozygotes, the decrease is only about 30%. MTHFR C677T polymorphism gene may alter folate metabolism and low folate intake may result in increased levels of homocysteine. This may lead to a decrease in DNA m ...
Volume 11 - Número 6 - Novembro / Dezembro de 2001
... echocardiography and Doppler ultrasound examination and/or left heart catheterization(14). Clinical findings include supravalvar aortic stenosis, a congenital narrowing of the ascending aorta, either localized or diffuse, originating at the superior margin of the sinuses of Valsalva just above the l ...
... echocardiography and Doppler ultrasound examination and/or left heart catheterization(14). Clinical findings include supravalvar aortic stenosis, a congenital narrowing of the ascending aorta, either localized or diffuse, originating at the superior margin of the sinuses of Valsalva just above the l ...
Case Report Section
... t(9;11). Additionally, leukemia with MLL/11q23 translocations are frequently associated with over expression of FLT3, therefore, targeted therapy inhibitors of FLT3 (a tyrosine kinase) may be beneficial for those patients. Currently there are only three reported cases in the literature with t(11;22) ...
... t(9;11). Additionally, leukemia with MLL/11q23 translocations are frequently associated with over expression of FLT3, therefore, targeted therapy inhibitors of FLT3 (a tyrosine kinase) may be beneficial for those patients. Currently there are only three reported cases in the literature with t(11;22) ...
FLUORESCENT PROTEIN IN Escherichia coli
... paradigm to how infections were treated. Since then many other antiobiotics were developed, e.g. streptomycin against tuberculosis. This meant that the leading cause of death changed from being infections to being noninfectious diseases, i.e. cancer, stroke, etc. Meanwhile, extended use of antibioti ...
... paradigm to how infections were treated. Since then many other antiobiotics were developed, e.g. streptomycin against tuberculosis. This meant that the leading cause of death changed from being infections to being noninfectious diseases, i.e. cancer, stroke, etc. Meanwhile, extended use of antibioti ...
Selective Mutation of Codons 204 and 213 of the
... pounds or related carcinogens. mutations in codon 204 have not previously been reported in It has been suggested that the biological properties of mutant any human or animal neoplasm. Codon 213, on the other hand, p53 proteins depend on the site of point mutations. Base is a fairly frequent site for ...
... pounds or related carcinogens. mutations in codon 204 have not previously been reported in It has been suggested that the biological properties of mutant any human or animal neoplasm. Codon 213, on the other hand, p53 proteins depend on the site of point mutations. Base is a fairly frequent site for ...
Bladder Cancer: Allelic Deletions at and around the Retinoblastoma
... other than 9p (p16), 13q (RB), and 17p (p53), including chromosomes 3p, 4p, 8p, 9q, and 11p (6 –10). It has been argued that the observation of all these changes indicates that p16, p53, and RB constitute just a few of a plenitude genes that are important, but also— on the contrary—that many changes ...
... other than 9p (p16), 13q (RB), and 17p (p53), including chromosomes 3p, 4p, 8p, 9q, and 11p (6 –10). It has been argued that the observation of all these changes indicates that p16, p53, and RB constitute just a few of a plenitude genes that are important, but also— on the contrary—that many changes ...
T cell antigen receptor diversity Generation of
... factors from the AP-1 family such as Fos and Jun. • Increases in intracellular calcium via IP3 IP3, produced by PLC-, binds to calcium channels in the ER and releases intracellular stores of Ca++ into the cytosol. Increased intracellular [Ca++] activate a phospatase, calcineurin, which in turn acti ...
... factors from the AP-1 family such as Fos and Jun. • Increases in intracellular calcium via IP3 IP3, produced by PLC-, binds to calcium channels in the ER and releases intracellular stores of Ca++ into the cytosol. Increased intracellular [Ca++] activate a phospatase, calcineurin, which in turn acti ...
T1 transgenic tobacco plants
... cultivar was found to have the best resistance to weevils while LC1 and LVN99 cultivars have low resistant ability. 2. ZmDEF1 gene (DNA)isolated from studied maize cultivars has 345 bp, it is made of an intron with 102 bp between two exons; ZmDEF1 gene (cDNA) has 243 bp codifying 80 amino acids. 3. ...
... cultivar was found to have the best resistance to weevils while LC1 and LVN99 cultivars have low resistant ability. 2. ZmDEF1 gene (DNA)isolated from studied maize cultivars has 345 bp, it is made of an intron with 102 bp between two exons; ZmDEF1 gene (cDNA) has 243 bp codifying 80 amino acids. 3. ...
Estimates of DNA and Protein Sequence Divergence: An
... Templeton et al. 1981) that the effects of the initial conditions on estimates of divergence are usually ignored. These initial conditions include whether the original population is polymorphic and to what extent. Templeton et al. (1981) show that for several species sufficient polymorphism exists t ...
... Templeton et al. 1981) that the effects of the initial conditions on estimates of divergence are usually ignored. These initial conditions include whether the original population is polymorphic and to what extent. Templeton et al. (1981) show that for several species sufficient polymorphism exists t ...