Julio`s MCB - Digital Access to Scholarship at Harvard
... Mitoferrin 1 (Mfrn1; Slc25a37) and mitoferrin 2 (Mfrn2; Slc25a28) function as essential mitochondrial iron importers for heme and Fe/S cluster biogenesis. A genetic deficiency of Mfrn1 results in a profound hypochromic anemia in vertebrate species. To map the cis-regulatory modules (CRMs) that contr ...
... Mitoferrin 1 (Mfrn1; Slc25a37) and mitoferrin 2 (Mfrn2; Slc25a28) function as essential mitochondrial iron importers for heme and Fe/S cluster biogenesis. A genetic deficiency of Mfrn1 results in a profound hypochromic anemia in vertebrate species. To map the cis-regulatory modules (CRMs) that contr ...
Extrapolation to the whole human genome
... Main non-processed pseudogene populations We examined the non-processed pseudogene populations for chromosomes 21 and 22 for their prevalent functional classes and compared them to the classes for genes predicted using GenomeScan (Yeh et al., 2001). The total number of InterPro motif assignments and ...
... Main non-processed pseudogene populations We examined the non-processed pseudogene populations for chromosomes 21 and 22 for their prevalent functional classes and compared them to the classes for genes predicted using GenomeScan (Yeh et al., 2001). The total number of InterPro motif assignments and ...
Cloning and expression analysis of follicle
... (GPHRs) (Fredriksson et al. 2003; Gether 2000). The members of this family are characterized by a large extracellular (EC) domain with nine leucine-rich receptor motifs and associated cysteine-rich sequences. This is followed by seven transmembrane (7TM) helices and a carboxy-terminal intracellular ...
... (GPHRs) (Fredriksson et al. 2003; Gether 2000). The members of this family are characterized by a large extracellular (EC) domain with nine leucine-rich receptor motifs and associated cysteine-rich sequences. This is followed by seven transmembrane (7TM) helices and a carboxy-terminal intracellular ...
Evolution of Immunoglobulin Kappa Chain Variable Region
... a sequence similarity of 95%–100%, and this duplication has not been found in the chimpanzee, gorilla, or orangutan (Ermert et al. 1995). From information on the overall sequence divergence between the two sets of duplicate genes (;1%), Schäble and Zachau (1993) suggested that the duplication occur ...
... a sequence similarity of 95%–100%, and this duplication has not been found in the chimpanzee, gorilla, or orangutan (Ermert et al. 1995). From information on the overall sequence divergence between the two sets of duplicate genes (;1%), Schäble and Zachau (1993) suggested that the duplication occur ...
Albinism - Harlem Children Society
... Chediak-Higashi Syndrome- not common form of albinism characterized by an abnormality in certain types of white blood cells. This type of albinism gives a lower chance for the immune system to fight off pathogens. Griscelli Syndrome- an extremely rare type of albinism. There are only 60 known case ...
... Chediak-Higashi Syndrome- not common form of albinism characterized by an abnormality in certain types of white blood cells. This type of albinism gives a lower chance for the immune system to fight off pathogens. Griscelli Syndrome- an extremely rare type of albinism. There are only 60 known case ...
Expression Differentiation Is Constrained to Low
... ABSTRACT Protein expression level is one of the strongest predictors of protein sequence evolutionary rate, with high-expression protein sequences evolving at slower rates than low-expression protein sequences largely because of constraints on protein folding and function. Expression evolutionary ra ...
... ABSTRACT Protein expression level is one of the strongest predictors of protein sequence evolutionary rate, with high-expression protein sequences evolving at slower rates than low-expression protein sequences largely because of constraints on protein folding and function. Expression evolutionary ra ...
NanoString™: User Guide | nCounter® Expression Data Analysis
... In order to count accurately, the Digital Analyzer only counts the codes that are unambiguously distinguishable. If codes overlap with each other in an image, the Digital Analyzer does not interpolate what those codes are; rather, it simply does not count them. This provides increased confidence tha ...
... In order to count accurately, the Digital Analyzer only counts the codes that are unambiguously distinguishable. If codes overlap with each other in an image, the Digital Analyzer does not interpolate what those codes are; rather, it simply does not count them. This provides increased confidence tha ...
Androgenic control of nucleic acid and protein synthesis in male
... An ever-increasing amount of experi- comprehensive molecular theories of sex mental effort has been expended over the hormone action. last 5 years toward examining various in( 1 ) It is well established that common termediate reactions involved in ribonu- pathways exist for the biosynthesis of cleic ...
... An ever-increasing amount of experi- comprehensive molecular theories of sex mental effort has been expended over the hormone action. last 5 years toward examining various in( 1 ) It is well established that common termediate reactions involved in ribonu- pathways exist for the biosynthesis of cleic ...
View the BIO 105 Study Guide
... *identify characteristics of living things and understand the difference between something that is living and something that is nonliving 2. Chemistry and how it relates to living things—atomic structure/bonding/pH/properties of water *define atom and energy *identify properties of atoms (protons, n ...
... *identify characteristics of living things and understand the difference between something that is living and something that is nonliving 2. Chemistry and how it relates to living things—atomic structure/bonding/pH/properties of water *define atom and energy *identify properties of atoms (protons, n ...
Gene Section VAV1 (vav 1 oncogene) Atlas of Genetics and Cytogenetics
... Vav1 encodes a highly unique protein that contains numerous modular motifs known to play a role in tyrosine-mediated signal transduction cascades, such as a dbl homology (DH) region, which exhibits a guanine nucleotide exchange factor (GEF) activity towards the Rho family GTPases; a pleckstrin homol ...
... Vav1 encodes a highly unique protein that contains numerous modular motifs known to play a role in tyrosine-mediated signal transduction cascades, such as a dbl homology (DH) region, which exhibits a guanine nucleotide exchange factor (GEF) activity towards the Rho family GTPases; a pleckstrin homol ...
Chapt. 14 Eukaryotic mRNA processing I: splicing 14.1 Genes are in
... • Most ‘higher eukaryotic’ genes coding for mRNA and tRNA (some rRNA) are interrupted by introns • Exons surround introns: contain sequences that finally appear in the mature RNA product – Genes for mRNAs have 0 to 362 exons (titin) – tRNA genes have either 0 or 1 exon Introns present in genes, not ...
... • Most ‘higher eukaryotic’ genes coding for mRNA and tRNA (some rRNA) are interrupted by introns • Exons surround introns: contain sequences that finally appear in the mature RNA product – Genes for mRNAs have 0 to 362 exons (titin) – tRNA genes have either 0 or 1 exon Introns present in genes, not ...
The Large Loop Repair and Mismatch Repair Pathways
... in the RAD1-dependent LLR pathway springs from the known enzymatic roles of those proteins during mitotic DNA repair and the observed effects on meiotic recombination and DNA repair upon deletion of the LLR genes (Kirkpatrick and Petes 1997). Given the characterized activities of Rad1/10p and Msh2/3 ...
... in the RAD1-dependent LLR pathway springs from the known enzymatic roles of those proteins during mitotic DNA repair and the observed effects on meiotic recombination and DNA repair upon deletion of the LLR genes (Kirkpatrick and Petes 1997). Given the characterized activities of Rad1/10p and Msh2/3 ...
array CGH - Unique The Rare Chromosome Disorder Support Group
... (imbalances) in your child’s DNA can be identified. From this, the gene content of any such imbalance can be established. ...
... (imbalances) in your child’s DNA can be identified. From this, the gene content of any such imbalance can be established. ...
Does Mendel`s work suggest that this is the only gene in the pea
... identified gene homologs in Pisum sativum (pea), Arabidopsis thaliana, and Festuca pratensis (meadow fescue), mutations of which partially disable plant senescence. The biochemical properties and map location of this gene in pea indicate that it is the same locus that determines yellow (I) and green ...
... identified gene homologs in Pisum sativum (pea), Arabidopsis thaliana, and Festuca pratensis (meadow fescue), mutations of which partially disable plant senescence. The biochemical properties and map location of this gene in pea indicate that it is the same locus that determines yellow (I) and green ...
Does Mendel`s work suggest that this is the only gene in the pea
... identified gene homologs in Pisum sativum (pea), Arabidopsis thaliana, and Festuca pratensis (meadow fescue), mutations of which partially disable plant senescence. The biochemical properties and map location of this gene in pea indicate that it is the same locus that determines yellow (I) and green ...
... identified gene homologs in Pisum sativum (pea), Arabidopsis thaliana, and Festuca pratensis (meadow fescue), mutations of which partially disable plant senescence. The biochemical properties and map location of this gene in pea indicate that it is the same locus that determines yellow (I) and green ...
MetaXcan: Summary Statistics Based Gene-Level
... showed that 80% of phenotype variability (in 12 diseases) can be attributed to DNAase I hypersensitivity sites, further highlighting the importance of transcript regulation in determining phenotypes [3]. Many transcriptome studies have been conducted where genotype and expression levels are assayed ...
... showed that 80% of phenotype variability (in 12 diseases) can be attributed to DNAase I hypersensitivity sites, further highlighting the importance of transcript regulation in determining phenotypes [3]. Many transcriptome studies have been conducted where genotype and expression levels are assayed ...
Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant
... pathway. As a note of caution, one should keep in mind that the phenotypic effect of genetic modifications of genetically altered animals in a nonhomogeneous genetic background are prone to epigenetic effects. However, we tried to minimize this risk by using double heterozygous animals throughout th ...
... pathway. As a note of caution, one should keep in mind that the phenotypic effect of genetic modifications of genetically altered animals in a nonhomogeneous genetic background are prone to epigenetic effects. However, we tried to minimize this risk by using double heterozygous animals throughout th ...
Enlis Genome Research - Release Notes
... - Main Application: Added Homozygous Regions Detector tool. Find regions of the genome with "runs" of consecutive homozygous variants. For rare disease analysis, these regions may indicate a consanguineous union, and provide a starting point for finding recessive disease. In tumor samples, these reg ...
... - Main Application: Added Homozygous Regions Detector tool. Find regions of the genome with "runs" of consecutive homozygous variants. For rare disease analysis, these regions may indicate a consanguineous union, and provide a starting point for finding recessive disease. In tumor samples, these reg ...
Speciation genes in plants - Oxford Academic
... we considered this to be self-evident, although we recognize that incompatibility alleles at some of these genes might be too rare to have a significant effect on gene flow between populations. For pre-pollination barriers, we considered that floral changes associated with observed shifts in the pol ...
... we considered this to be self-evident, although we recognize that incompatibility alleles at some of these genes might be too rare to have a significant effect on gene flow between populations. For pre-pollination barriers, we considered that floral changes associated with observed shifts in the pol ...
SCAPE-IntroductionToTaverna-myExper
... Taverna Features - Overview • Access to remote, distributed or local services and resources • Enables service interoperability and integration • Automates data flow between services • Implicit iteration over data sets, list handling and control links to determine order of service invocation • Extens ...
... Taverna Features - Overview • Access to remote, distributed or local services and resources • Enables service interoperability and integration • Automates data flow between services • Implicit iteration over data sets, list handling and control links to determine order of service invocation • Extens ...
Chapter 10
... – messenger RNA (mRNA) determines the amino acid sequence of the protein during translation – ribosomal RNA (rRNA) is one of the components of the ribosome involved in translation – transfer RNA (tRNA) is a small RNA that can bind an amino acid at one end, and mRNA at the other end. It acts as an ad ...
... – messenger RNA (mRNA) determines the amino acid sequence of the protein during translation – ribosomal RNA (rRNA) is one of the components of the ribosome involved in translation – transfer RNA (tRNA) is a small RNA that can bind an amino acid at one end, and mRNA at the other end. It acts as an ad ...
Major City Chiefs Position Paper on Sworn vs
... operational aspects of the organization. If this is not possible, a supporting deputy position should be considered. II. National standards, where they do not exist, should be developed for individual forensic disciplines. These national standards, once adopted, should be incorporated into the appro ...
... operational aspects of the organization. If this is not possible, a supporting deputy position should be considered. II. National standards, where they do not exist, should be developed for individual forensic disciplines. These national standards, once adopted, should be incorporated into the appro ...
Distortion of quantitative genomic and expression
... QPCR and data analysis were performed using the Chromo4 QPCR system (BioRad Laboratories, Hercules, CA). Primers and amplified intervals were verified for unique genomic representation using BLAT (17) and WU-BLAST (Table 2). Each 50 ml reaction contained 0.5 mM of each primer, 50 ng Cot-1 template o ...
... QPCR and data analysis were performed using the Chromo4 QPCR system (BioRad Laboratories, Hercules, CA). Primers and amplified intervals were verified for unique genomic representation using BLAT (17) and WU-BLAST (Table 2). Each 50 ml reaction contained 0.5 mM of each primer, 50 ng Cot-1 template o ...
Induction of XIST expression from the human active
... reduce levels of DNA methylation, causes reactivation of genes on the inactive X chromosome, particularly in somatic cell hybrids (reviewed in 7). The XIST gene is the only gene known to be expressed exclusively from the inactive X chromosome (8) and is localised to the smallest interval of the X ch ...
... reduce levels of DNA methylation, causes reactivation of genes on the inactive X chromosome, particularly in somatic cell hybrids (reviewed in 7). The XIST gene is the only gene known to be expressed exclusively from the inactive X chromosome (8) and is localised to the smallest interval of the X ch ...
Genome-wide histone modification patterns in
... more phylogenetically restricted. Most notably, two major repressive marks are not found in the budding yeast S. cerevisiae. The polycomb-associated modification H3K27me3 is widespread in multicellular organisms, where it plays a key role in control of cell state inheritance (SCHUETTENGRUBER et al. ...
... more phylogenetically restricted. Most notably, two major repressive marks are not found in the budding yeast S. cerevisiae. The polycomb-associated modification H3K27me3 is widespread in multicellular organisms, where it plays a key role in control of cell state inheritance (SCHUETTENGRUBER et al. ...