• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Gene Section SRSF1 (serine/arginine rich splicing factor 1) -
Gene Section SRSF1 (serine/arginine rich splicing factor 1) -

... modular structure with two RNA recognition motifs (RRM) that provide RNA-binding specificity and one arginine/serine-rich domain (RS), involved in protein-protein interactions that facilitate recruitment of the spliceosome. The RS domain acts also as a nuclear localization signal, controlling the su ...
שקופית 1
שקופית 1

... aspects of hormone biosynthesis (the assembly of the heterodimer, formation of conformational-sensitive epitopes and the activation of the cognate receptor). However, this domain is missing the set of Olinked glycans and lacks the hallmark function of prolonging the circulatory survival and determin ...
Semantic WebMelbourn.. - Buffalo Ontology Site
Semantic WebMelbourn.. - Buffalo Ontology Site

... To check this information, we can list the checksums in a local file, and then set up some FOPL rules that say "if file 'a' contains the information Joe loves mary and has the checksum md5:0qrhf8q3hfh, then record SuccessA", "if file 'b' contains the information MJS is equivalent to Mary, and has th ...
North Kitsap High School PAL Program
North Kitsap High School PAL Program

... compare ideas of Hutton, Lyell, Lamarck, and Malthus, describe how natural variation is used in artificial selection, describe how natural selection is related to species’ fitness, identify evidence Darwin used to present his case for evolution by natural selection, and state his theory. (16) Explai ...
Unit F215 - Control, genomes and environment - Medium band
Unit F215 - Control, genomes and environment - Medium band

... and moves to the ribosome where it attaches. In the cytoplasm are tRNA molecules that are attached to amino acids. On the bottom of the tRNA molecule is a triplet and this will match up with the bases on the mRNA. As the tRNA molecules line up, the amino acids join with a glycosidic bond. This carri ...
channel 1 gene dosage
channel 1 gene dosage

... functional gene dosage 0) and the compound heterozygote (adr/mto) showed overt myotonia. Values averaged over the n/m are given ± S.E.M. values (bars). Values for heterozygous animals (functional gene dosage 1) are not significantly different from those of homozygous wild-type animals (functional ge ...
Internalization of the chicken growth hormone receptor complex and
Internalization of the chicken growth hormone receptor complex and

... levels are low, as is the case in adult chickens, binding and degradation of internalized receptors are reduced. In general, the presence of intracellular receptors ensures quick reversal of transient GH refractoriness as result of receptor internalization, since at least in mammals, GH receptors ca ...
Gene Section CPM (carboxypeptidase M) Atlas of Genetics and Cytogenetics
Gene Section CPM (carboxypeptidase M) Atlas of Genetics and Cytogenetics

... vitamin D3 responsive element and Sp1. The distal promoter (~ 30 kb upstream of the coding region) differs from the proximal promoter in that it mainly consists of repetitive elements and lacks common promoter elements. Inr sequences and a putative DPE were found together with putative Ets, C/EBP, O ...
Pom-Pom_Genetics
Pom-Pom_Genetics

... F: How many Blondes does it take to…?: OK, let’s try hair color. There may be as many as eleven genes that affect your hair color. Perhaps the most significant gene is MC1R on chromosome 16. Geneticists aren’t totally sure what the other genes are. We can approximate this polygenic inheritance if w ...
Congenital Adrenal Hyperplasia (CAH)
Congenital Adrenal Hyperplasia (CAH)

... What happens after the baby is born? If the diagnosis of CAH has definitely been excluded no further action is necessary. If a baby is known to be at a 1 in 2 (or 1 in 4) risk of CAH, further testing will depend on the available information on genetic changes. Gene tracking studies (known as linkage ...
Mendelian and Non-Mendelian Regulation of Gene Expression in
Mendelian and Non-Mendelian Regulation of Gene Expression in

... expression levels of 22,242 genes that were detected in both parents and at least 90% of the IBM RILs. The mean expression levels in the RILs were similar to the mid-parent values for most genes (Figure 1B). Transgressive segregation, defined here as at least 10% of RILs exhibiting expression levels ...
Genomic Analysis of Hox Clusters in the Sea Lamprey
Genomic Analysis of Hox Clusters in the Sea Lamprey

... The entire homeobox was sequenced from each clone, which had a unique restriction map. Nucleotide sequences are available in GenBank, accession numbers AF410908–AF410925. The deduced amino acid sequences are shown aligned to mouse and amphioxus sequences in Figure 2. To assign genes to Hox cognate g ...
Lecture 4
Lecture 4

... Ends in Rare restriction enzyme site ...
View PDF
View PDF

... TP-PCR8, 18, 19 which uses triplet primers to produce a mixture of PCR fragments of different sizes is much easier and faster. Although expansions in all size ranges can be detected by TP-PCR, no reliable information about the length of the expanded repeat could be obtained because of extinction of ...
Molecular Diagnostics in Clinical Microbiology
Molecular Diagnostics in Clinical Microbiology

... acid amplification techniques (NAATs) have taken an irreversible position in the diagnostic field of infectious diseases. Pathogens can be detected in qualitative and quantitative NAAT strategies by selection of species-specific nucleic acid targets. Moreover, NAATs allow a better understanding of m ...
Molecular Evolution, Functional Variation, and Proposed
Molecular Evolution, Functional Variation, and Proposed

... Taxonomic Sampling and Collection The representation of taxa in different analyses is summarized in table 2. Our goal was to capture the breadth of diversity within Sicariidae, guided by previous phylogenetic work (Binford et al. 2008, fig. 1). To do this, we include at least one representative of e ...
Report Number of Nuclear Divisions in the Drosophila Blastoderm
Report Number of Nuclear Divisions in the Drosophila Blastoderm

... expression of CyclinB. Although the altered levels of RNA polymerase II in X161 mutants probably affect expression of many genes during oogenesis, these changes seem not to matter in functional terms, given the overall normal morphology and specific mutant phenotype. It is conceivable that transcrip ...
Identification of Genes Needed for Regeneration, Stem Cell
Identification of Genes Needed for Regeneration, Stem Cell

... adult planarians and reside in the parenchyma. Following injury, a neoblast proliferative response is triggered, generating a regeneration blastema consisting of initially undifferentiated cells covered by epidermal cells. Moreover, essentially all tissues in adult planarians turn over and are repla ...
Equilibrium Statistics of Channel-confined DNA
Equilibrium Statistics of Channel-confined DNA

... questions and for helping me answer mine. I have also very much enjoyed sharing an office with Camilla, Joachim, Katarina, Marina and Jonas (not all at the same time). I’m sorry for ruining your workflow with questions, drumming and ice cream. Alexander Björling, Jonas Einarsson and Marina Rafajlovi ...
Alu - Environmental
Alu - Environmental

... • The LINE (Long INterspersed Element) L1 supplies the reverse transcriptase needed for Alu to jump • L1 is a defective retrovirus • It nicks the DNA close to the sequence AATTTT • The AAAA of Alu transcript binds to the TTTT of the nicked DNA – the acts as a primer for the L1 to bind to ...
Vegetative incompatibility in filamentous fungi: Podospora and
Vegetative incompatibility in filamentous fungi: Podospora and

... Minor mutational events can generate incompatible geneto-gene interactions. For instance, several different single amino-acid replacements in the P. anserina het-S gene product give rise to a protein of the antagonistic [Het-s] specificity [19,20•]. Similarly, single amino-acid substitutions in the ...
Increased transcription rates correlate with increased reversion rates
Increased transcription rates correlate with increased reversion rates

... transcription in derepressed genes were correlated with increased reversion rates. Rates of leuB and argH mRNA synthesis were determined using half-lives and concentrations, during exponential growth and at several time points during 30 min of amino acid starvation. Changes in mRNA concentration wer ...
Genome Projector: zoomable genome map with multiple views
Genome Projector: zoomable genome map with multiple views

... stripes depending on the strand), GC content (brown lines), GC skew (yellow lines). Replication origin and terminus predicted from the cumulative GC skew shift points at single base pair resolution are also labelled, with a yellow line cutting through the genome, segregating the two replichores. Thi ...
Hereditary Hemochromatosis Since Discovery of the HFE Gene
Hereditary Hemochromatosis Since Discovery of the HFE Gene

... higher than expected if H63D or a genetically linked modifier did not contribute to the phenotype (5, 15 ). The C282Y/H63D compound heterozygous genotype is postulated to have a reduced penetrance [estimated to be 0.44 –1.5% (5, 9, 10 )]. Combined allele and genotype frequencies for C282Y and H63D a ...
Genes Involved in Sister Chromatid Separation and Segregation in
Genes Involved in Sister Chromatid Separation and Segregation in

... added back to prevent cells from entering the next cell cycle. All experiments were repeated at least twice with similar results and at least 100 cells were counted at each time point. Stock solutions of inhibitors were stored at ⫺20⬚: 30 mg/ml benomyl (DuPont, Wilmington, DE) in DMSO, 10 mg/ml noco ...
< 1 ... 44 45 46 47 48 49 50 51 52 ... 1045 >

Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report