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GENETICS accepted
GENETICS accepted

... A necessary early step in crossing over is the SPO11-dependent formation of double-strand breaks (DSBs) (KEENEY et al. 1997). In S. cerevisiae, at least nine other proteins interact with SPO11 to regulate the recruitment and activation of SPO11 (KEENEY and NEALE 2006). These proteins that regulate t ...
Running title Variation in Barley Brassinosteroid
Running title Variation in Barley Brassinosteroid

... required to enhance the genetic toolbox in order to facilitate efficient marker-assisted breeding. The mutations and the corresponding genes that enabled the Green Revolution in wheat and rice have been identified (Hedden, 2003). They all relate to gibberellin metabolism and signal transduction. It ...
Assessing the Probative Value of DNA Evidence
Assessing the Probative Value of DNA Evidence

... We recognise, nonetheless, that certain parts of the following discussion may be of greater interest and practical utility to some criminal justice professionals than to others. Our hope is that judges, lawyers and forensic scientists will be able to extrapolate from the common core and adapt our ge ...
LAZY1 controls rice shoot gravitropism through
LAZY1 controls rice shoot gravitropism through

... LA1-GFP, CaMV35S::LA1ΔN100-GFP, CaMV35S::LA1ΔNLSGFP and CaMV35S::GFP were constructed. LA1ΔN100 is the truncated LA1 with a deletion of amino-acid residues1-100 that contain a predicted transmembrane domain. LA1ΔNLS refers to the LA1 truncated from amino-acid residues 286 to 312, a segment containin ...
Application to Modify an Approved Exempt or Notifiable Low Risk
Application to Modify an Approved Exempt or Notifiable Low Risk

... I am aware of my responsibilities in relation to ensuring that any personnel conducting this work are appropriately trained and are aware of and also follow the relevant guidelines and regulations. I have considered the potential risks that the conduct of this dealing could pose to people and/or the ...
PDF
PDF

... activity causes developmental defects from embryogenesis onwards in white light. Cotyledon development and number are altered in hat3 athb4 embryos, and these defects correlate with changes in auxin distribution and response. athb2 gain-of-function mutation and ATHB2 expression driven by its promote ...
Sample pages 2 PDF
Sample pages 2 PDF

... into exon 2. In fact, the elimination of exon 1b, as seen in Mitfmi–rw mice, in which the upstream exon A is spliced directly into exon 2, creates mRNAs with premature stop codons (32,33). Based on the observed gene structure, the single Mitf gene of mammals could theoretically give rise to at least ...
Technical Targets
Technical Targets

... substrates. WT: wild type. Fold changes are based on control cultures grown in argon gas. ...
video slide - Dublin City Schools Home
video slide - Dublin City Schools Home

... A Closer Look: Obtaining the Gene of Interest • How can a researcher obtain DNA that encodes a particular gene of interest? • The “shotgun” approach is one way to synthesize a gene of interest. – Millions of recombinant plasmids containing different segments of foreign DNA are produced. – This coll ...
Essential Bioinformatics and Biocomputing (LSM2104
Essential Bioinformatics and Biocomputing (LSM2104

... genes/proteins? (literature search, data mining) • How to design a new drug to control it? – If 3D structure is known or can be derived, structure-based drug design can be conducted (molecular modeling, docking) – If 3D structure not known, are there any molecules known to interact with this protein ...
Linkage, Recombination, and the Mapping of Genes on Chromosomes
Linkage, Recombination, and the Mapping of Genes on Chromosomes

... • Mitotic recombination: Rarely, recombination occurs during mitosis. In multicellular organisms, mitotic recombination can produce genetic mosaicism in which different cells have different genotypes. ...
Recombinant DNA technology - The Centre for Plant Sciences
Recombinant DNA technology - The Centre for Plant Sciences

... is taken up in parallel to such transport processes. This is very inefficient, but approximately 1 in 100.000 (105) plasmids makes it into an E.coli. To get more than just one transformation event, you should use much more than 105 plasmids, more like 109 or 1010, and you have to use enough bacteria ...
Nanopore Unzipping of Individual DNA Hairpin Molecules
Nanopore Unzipping of Individual DNA Hairpin Molecules

... duplex region sequence, and that the intercept depends strongly on the duplex region energy. We also present the first nanopore dynamic force measurements (time varying force). Our results are in agreement with the ~log(V_ ) dependence at high V_ (where V_ is the loading rate) observed by other metho ...
Mutations at the Darkener of apricot Locus Modulate Transcript
Mutations at the Darkener of apricot Locus Modulate Transcript

... to T 4 and produces a truncated mRNA. T h e resultant protein retains activity, and this allele is classified as a hypermorph, which is due to an overaccumulation of T 4 mRNA (CAMPUZANO et al. ...
SALSA MLPA KIT ME003-A1 Tumor suppressor-3 - MRC
SALSA MLPA KIT ME003-A1 Tumor suppressor-3 - MRC

... islands upstream of genes for which an altered methylation status in one or more types of tumours has been reported in literature. In case interesting results are obtained by users, it is possible to develop methylation kits specific for a certain tumour in collaboration with MRC-Holland. Interpreta ...
New functions of the Drosophila rhomboid gene
New functions of the Drosophila rhomboid gene

... to appropriate cells at a variety of developmental stages. One difficulty in analyzing the role of ectopic rho expression during many developmental stages such as embryogenesis is that rho is often expressed in many different cell types simultaneously. This complicates interpretation of resulting he ...
The Effect of OmpA Expression on Hfr Conjugation Efficiency
The Effect of OmpA Expression on Hfr Conjugation Efficiency

... Hfr Conjugation. The conjugation procedure was previously described (8). Briefly, an overnight culture of donor strain HfrC was diluted 1:25 in LB broth and incubated at 37oC for 3 hours. Overnight cultures of recipient strains C149, C156, and C158 both with and without the pCCK06-1 plasmid were dil ...
PowerPoint Presentation - No Slide Title
PowerPoint Presentation - No Slide Title

The causal meaning of Fisher`s average effect
The causal meaning of Fisher`s average effect

The amelogenin gene
The amelogenin gene

... protein is now well characterized from the data of amino acid sequences which have been shown to be at a high degree of homology between all species investigated to date. The gene structure of this protein has been demonstrated and it is confirmed that there are two amelogenin genes, one on the X.ch ...
gene mapping, marker gene mapping, marker-assisted
gene mapping, marker gene mapping, marker-assisted

... The aquaculture genetics projects were developed based on long-term efforts of selective breeding programs. These projects are dependent upon one another so that the maximum benefits will be obtained by using the integrated genetic improvement approaches. For instance, gene mapping will produce more ...
Gene Mapping, Marker-Assisted Selection, Gene Cloning, Genetic
Gene Mapping, Marker-Assisted Selection, Gene Cloning, Genetic

... The aquaculture genetics projects were developed based on long-term efforts of selective breeding programs. These projects are dependent upon one another so that the maximum benefits will be obtained by using the integrated genetic improvement approaches. For instance, gene mapping will produce more ...
Query Results
Query Results

... The core of the server is a MySQL database of virtual genomic SAGE tags with confidence assignments The module I is linked to NCBI BLAST server and to the Saccharomyces Genome Database (SGD) and does not require any input from the user. The modules II and III requires experimental tag sequences and ...
Obesity — a genetic disease of adipose tissue?
Obesity — a genetic disease of adipose tissue?

... gene–environment interactions is given in Fig. 1. One of these genes may be a major one and the others could be minor obesity genes. The particular major and minor obesity genes may differ between families or ethnic groups. In the rest of this paper I discuss the relative importance of genes with a ...
HED - National Foundation for Ectodermal Dysplasias
HED - National Foundation for Ectodermal Dysplasias

... from our father. Despite the importance of DNA (it makes us what we are), it is delicate and may change as it passes from one generation to the next. Many of the changes in DNA, called mutations, are harmful; that is, they may lead to abnormal development or function. Second, short segments of DNA c ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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