Respiratory Epithelial Gene Expression in Patients with Mild and
... Despite having identical cystic fibrosis transmembrane conductance regulator genotypes, individuals with ⌬F508 homozygous cystic fibrosis (CF) demonstrate significant variability in severity of pulmonary disease. This investigation used high-density oligonucleotide microarray analysis of nasal respi ...
... Despite having identical cystic fibrosis transmembrane conductance regulator genotypes, individuals with ⌬F508 homozygous cystic fibrosis (CF) demonstrate significant variability in severity of pulmonary disease. This investigation used high-density oligonucleotide microarray analysis of nasal respi ...
Genetic Polymorphism and Cancer Susceptibility: Fourteenth
... ST1B1>ST1C1>ST1A1. A genetic polymorphism has been described for a human ST but is only manifest as in vitro thermal stability of the platelet enzyme, although activity is found in the liver and intestine. T. Yokoi (Hokkaido University, Sapporo. Japan) discussed studies using caffeine to phenotype J ...
... ST1B1>ST1C1>ST1A1. A genetic polymorphism has been described for a human ST but is only manifest as in vitro thermal stability of the platelet enzyme, although activity is found in the liver and intestine. T. Yokoi (Hokkaido University, Sapporo. Japan) discussed studies using caffeine to phenotype J ...
letter Widespread aneuploidy revealed by DNA microarray expression profiling
... mutants profiled exhibited chromosome-wide expression biases, leading to spurious correlations among profiles. Competitive hybridization of genomic DNA from the mutant strains and their isogenic parental wild-type strains showed they were aneuploid for whole chromosomes or chromosomal segments. Expr ...
... mutants profiled exhibited chromosome-wide expression biases, leading to spurious correlations among profiles. Competitive hybridization of genomic DNA from the mutant strains and their isogenic parental wild-type strains showed they were aneuploid for whole chromosomes or chromosomal segments. Expr ...
found only in 2.25% of all muscle biopsies analyzed
... the nuclear lamina, a filamentous network underlying the inner face of the nuclear membrane. A-type lamins are encoded by the same gene: LMNA, as a result of alternative splicing. Up to date, at least nine pathologies, described as laminopathies, have been associated with mutations in LMNA. One of th ...
... the nuclear lamina, a filamentous network underlying the inner face of the nuclear membrane. A-type lamins are encoded by the same gene: LMNA, as a result of alternative splicing. Up to date, at least nine pathologies, described as laminopathies, have been associated with mutations in LMNA. One of th ...
Dynamic Signalling and Gene Expression Regulation
... repellents, but then adapt to a constant level of the signal. Our own sense of smell operates this way, so we refer to this type of response as a ‘sniffer.’ ...
... repellents, but then adapt to a constant level of the signal. Our own sense of smell operates this way, so we refer to this type of response as a ‘sniffer.’ ...
point mutations - Plant Developmental Biology
... male bees, wasps, and ants are examples of monoploids monoploids are sterile (no meiosis possible and propagation via mitotic gametes) ...
... male bees, wasps, and ants are examples of monoploids monoploids are sterile (no meiosis possible and propagation via mitotic gametes) ...
Multifractal analysis of DNA sequences using a novel chaos
... two of them on the 1=f spectrum of DNA sequences [3]. By mapping the sequence onto a (1D) walk, Peng and others have built a kind of interface, whose statistics were used to probe the range of correlation of the sequences [4,5]. Linguistic features were claimed to have been found in noncoding DNA s ...
... two of them on the 1=f spectrum of DNA sequences [3]. By mapping the sequence onto a (1D) walk, Peng and others have built a kind of interface, whose statistics were used to probe the range of correlation of the sequences [4,5]. Linguistic features were claimed to have been found in noncoding DNA s ...
Gene Expression Microarray Analysis of Archival FFPE Samples
... cancer patients.2 These studies utilized high quality RNA extracted from fresh frozen tumor tissue. Many laboratories are trying to develop methods to allow a similar degree of gene expression profiling using FFPE samples.3 FFPE samples represent the largest source of archival biological material av ...
... cancer patients.2 These studies utilized high quality RNA extracted from fresh frozen tumor tissue. Many laboratories are trying to develop methods to allow a similar degree of gene expression profiling using FFPE samples.3 FFPE samples represent the largest source of archival biological material av ...
why care
... thread of life that connects generations. Mitosis is used for all other cell divisions. ...
... thread of life that connects generations. Mitosis is used for all other cell divisions. ...
MI Unit 3 Study Guide
... Scientists have discovered that one of the differences between healthy cells and cancer cells is which genes are turned on in each. Scientists can compare the gene expression patterns between healthy and cancer cells through the use of DNA microarray technology. Every cell in the human body contains ...
... Scientists have discovered that one of the differences between healthy cells and cancer cells is which genes are turned on in each. Scientists can compare the gene expression patterns between healthy and cancer cells through the use of DNA microarray technology. Every cell in the human body contains ...
Proteomics tools and applications
... Proteins are the agents that, within the cell, “do what it is needed to do” One of the major findings, of the new postgenomic era, is that the old paradigm according to which a gene codes for a single protein is no longer valid In fact, due to alternative splicing and post translational modificati ...
... Proteins are the agents that, within the cell, “do what it is needed to do” One of the major findings, of the new postgenomic era, is that the old paradigm according to which a gene codes for a single protein is no longer valid In fact, due to alternative splicing and post translational modificati ...
mv-lect-06-virus-repl-stratigies
... found in uninfected host cells and must therefore be encoded in the viral genome and expressed during infection. In some families of RNA viruses, the corresponding polymerase and other associated enzymes with the viral genome are co-packaged during the viral assembly. ...
... found in uninfected host cells and must therefore be encoded in the viral genome and expressed during infection. In some families of RNA viruses, the corresponding polymerase and other associated enzymes with the viral genome are co-packaged during the viral assembly. ...
Sex determination in Bombyx mori
... The DM domain of BmDSX shows 80% of identity with that of Drosophila DSX. Other functional regions of DSX, such as the OD2 domain, are also well conserved CURRENT SCIENCE, VOL. 83, NO. 4, 25 AUGUST 2002 ...
... The DM domain of BmDSX shows 80% of identity with that of Drosophila DSX. Other functional regions of DSX, such as the OD2 domain, are also well conserved CURRENT SCIENCE, VOL. 83, NO. 4, 25 AUGUST 2002 ...
B.2 Specific Aims. The term `epigenetics` literally means `above the
... phenomena, and indicates the covalent transfer of a methyl group to the carbon at position 5 of cytosine residues,[2] usually within regions of DNA in which cytosine occurs next to a guanine nucleotide (CpG sites). DNA methylation is linked to the regulation of gene expression and transcriptional si ...
... phenomena, and indicates the covalent transfer of a methyl group to the carbon at position 5 of cytosine residues,[2] usually within regions of DNA in which cytosine occurs next to a guanine nucleotide (CpG sites). DNA methylation is linked to the regulation of gene expression and transcriptional si ...
Geometrical ordering of DNA in bacteria
... simulations of compacted DNA. (A and B) show the position of genes along the cell axis as function of their position on the chromosomal map for an average chromosome configuration as obtained from our theoretical model in which compacted DNA is represented by a chain of blobs. The position on the ch ...
... simulations of compacted DNA. (A and B) show the position of genes along the cell axis as function of their position on the chromosomal map for an average chromosome configuration as obtained from our theoretical model in which compacted DNA is represented by a chain of blobs. The position on the ch ...
Bt - Biology
... genes passed on this trait will be exhibited, but if a dominant gene is present then the recessive gene will not be exhibited. Attached earlobes are = f ...
... genes passed on this trait will be exhibited, but if a dominant gene is present then the recessive gene will not be exhibited. Attached earlobes are = f ...
The Case of the Cumbersome Chromosomes
... Homologous chromosomal regions are designated by the numbers 1-6. The effects of these aberrations depend on a variety of factors. First, the original break in the chromosomal material could have a dramatic effect on gene expression if it occurs in a regulatory region or in a coding region. In fact, ...
... Homologous chromosomal regions are designated by the numbers 1-6. The effects of these aberrations depend on a variety of factors. First, the original break in the chromosomal material could have a dramatic effect on gene expression if it occurs in a regulatory region or in a coding region. In fact, ...
Table S10
... (T6SS), and Type VII secretion system (T7SS) or the Chaperone-Usher pathway. The T2SS, in general, has been accredited with the export of proteins into target host cells as well as to the extracellular milieu, thereby promoting virulence and/or environmental fitness of the concerned organism [1]. Th ...
... (T6SS), and Type VII secretion system (T7SS) or the Chaperone-Usher pathway. The T2SS, in general, has been accredited with the export of proteins into target host cells as well as to the extracellular milieu, thereby promoting virulence and/or environmental fitness of the concerned organism [1]. Th ...
Effects of adenovirus delivered Flt
... While the main route of fatty acid metabolism is through beta-oxidation, some minor metabolic pathways such as omega oxidation also contribute to the metabolism of fatty acids and other molecules. Omega oxidation occurs in the endoplasmic reticulum rather than the mitochondria, the site of beta-ox ...
... While the main route of fatty acid metabolism is through beta-oxidation, some minor metabolic pathways such as omega oxidation also contribute to the metabolism of fatty acids and other molecules. Omega oxidation occurs in the endoplasmic reticulum rather than the mitochondria, the site of beta-ox ...
S4 Text.
... These are excerpts from the lab manual written by the instructor for use in our course (omitted pages/sections feature course-specific information not needed to carry out these experiments at a different institution). The two modules - 1) inverse PCR using genomic DNA extracted from adult flies for ...
... These are excerpts from the lab manual written by the instructor for use in our course (omitted pages/sections feature course-specific information not needed to carry out these experiments at a different institution). The two modules - 1) inverse PCR using genomic DNA extracted from adult flies for ...
Water at DNA surfaces: Ultrafast dynamics in minor groove recognition
... exponentials (ps and ns ranges) and to depend on its concentration. The enhancement of the ps component, characteristic of high pH decay (20) at high concentration, may suggest the presence of ground-state conformations whose equilibrium changes with concentrations and兾or aggregation; a subset of t ...
... exponentials (ps and ns ranges) and to depend on its concentration. The enhancement of the ps component, characteristic of high pH decay (20) at high concentration, may suggest the presence of ground-state conformations whose equilibrium changes with concentrations and兾or aggregation; a subset of t ...
Functional Analysis of A Novel Splicing Mutation in The Mutase
... most frequent nucleotide at position of -3 of the acceptor splice site is C. The second prioritized base is either A or T, and the least frequent is G (23). The Novel mutation reported here leads to retention of the intron 12, which adds 10 amino acids to the encoding protein after exon 12 but also ...
... most frequent nucleotide at position of -3 of the acceptor splice site is C. The second prioritized base is either A or T, and the least frequent is G (23). The Novel mutation reported here leads to retention of the intron 12, which adds 10 amino acids to the encoding protein after exon 12 but also ...
Regions of XY homology in the pig X pseudoautosomal region
... the Y noted that the long arm (Yq) contains a large C band, indicating that this arm contains a substantial proportion of constitutive heterochromatin [3,10]. Subsequent physical mapping of bacterial artificial chromosome (BAC) clones containing Y chromosome content by fluorescence in-situ hybridisa ...
... the Y noted that the long arm (Yq) contains a large C band, indicating that this arm contains a substantial proportion of constitutive heterochromatin [3,10]. Subsequent physical mapping of bacterial artificial chromosome (BAC) clones containing Y chromosome content by fluorescence in-situ hybridisa ...
3: The Technologies
... There are two broad classes of cells: prokaryotic and eukaryotic. The classes are basically defined by the manner in which the genetic material is housed. Prokaryotes, generally considered the simpler of the two classes, include bacteria. Their genetic material is not housed in a separate structure ...
... There are two broad classes of cells: prokaryotic and eukaryotic. The classes are basically defined by the manner in which the genetic material is housed. Prokaryotes, generally considered the simpler of the two classes, include bacteria. Their genetic material is not housed in a separate structure ...
Journal of Bacteriology
... host-specific nod gene products, resulting in effective nodules on a limited range of host plants (1, 16, 38, 48). Other nod genes identified in R. leguminosarum bv. viciae are nodlJ, nodMNT (6, 54, 55), and nodO (11, 15). Mutations in these genes have more or less severe effects on nodulation, depe ...
... host-specific nod gene products, resulting in effective nodules on a limited range of host plants (1, 16, 38, 48). Other nod genes identified in R. leguminosarum bv. viciae are nodlJ, nodMNT (6, 54, 55), and nodO (11, 15). Mutations in these genes have more or less severe effects on nodulation, depe ...