Supplementary Information (doc 63K)
... A training cohort of 30 CLL samples with known TP53/ATM molecular and functional characteristics was used to test the newly designed RT-MLPA. TP53 and ATM molecular status was determined using FISH and sequencing. Only samples with biallelic TP53 (TP53 mutation + 17p deletion) and biallelic ATM (ATM ...
... A training cohort of 30 CLL samples with known TP53/ATM molecular and functional characteristics was used to test the newly designed RT-MLPA. TP53 and ATM molecular status was determined using FISH and sequencing. Only samples with biallelic TP53 (TP53 mutation + 17p deletion) and biallelic ATM (ATM ...
Green Revolution Genes
... The wild-type (non-mutant) alleles of Rht-B1b and Rht-D1b (designated Rht-B1a and Rht-D1a, respectively) were isolated a few years ago (Peng et al., 1999) and shown to encode DELLA proteins, which are components of the GA signal transduction pathway. As explained in chapter 20, DELLA proteins act as ...
... The wild-type (non-mutant) alleles of Rht-B1b and Rht-D1b (designated Rht-B1a and Rht-D1a, respectively) were isolated a few years ago (Peng et al., 1999) and shown to encode DELLA proteins, which are components of the GA signal transduction pathway. As explained in chapter 20, DELLA proteins act as ...
Understanding Our Environment
... Stern - Introductory Plant Biology: 9th Ed. - All Rights Reserved - McGraw Hill Companies ...
... Stern - Introductory Plant Biology: 9th Ed. - All Rights Reserved - McGraw Hill Companies ...
Conservation of gene function in behaviour
... to be conserved is the structure of the clock molecular mechanism but not necessarily each particular gene or gene product. (See also a discussion of relationship of the cyanobacterial clock to eukaryote clocks [43]). While some genes play the same roles in insects and mammals (e.g. period), others ...
... to be conserved is the structure of the clock molecular mechanism but not necessarily each particular gene or gene product. (See also a discussion of relationship of the cyanobacterial clock to eukaryote clocks [43]). While some genes play the same roles in insects and mammals (e.g. period), others ...
Southern Blot Analysis of Plasmids pRIT4501 and - RIT
... support, and challenging it with a small, labeled, single-stranded DNA (probe) under conditions that promote hybridization. If the probe sequence is found within the target DNA, the probe will bind to its complementary sequence on the support. All that is left is to detect probe binding. Probe is us ...
... support, and challenging it with a small, labeled, single-stranded DNA (probe) under conditions that promote hybridization. If the probe sequence is found within the target DNA, the probe will bind to its complementary sequence on the support. All that is left is to detect probe binding. Probe is us ...
the south african dna project approval process
... The project developer then submits the project details to the DNA in the form of a Project Design Document (PDD). This must be accompanied by a completed application form. Note that the PDD should already have been validated by the Designated Operational Entity at this stage. See the UNFCCC website ...
... The project developer then submits the project details to the DNA in the form of a Project Design Document (PDD). This must be accompanied by a completed application form. Note that the PDD should already have been validated by the Designated Operational Entity at this stage. See the UNFCCC website ...
Section 2: Energy Flow in Ecosystems
... • One kind of DNA sequence that can be bound by an activator is called an enhancer. • Enhancers are often located thousands of bases away from the promoter. • A loop in the DNA forms as the factors interact at the promoter site. • Each factor may also affect other factors. ...
... • One kind of DNA sequence that can be bound by an activator is called an enhancer. • Enhancers are often located thousands of bases away from the promoter. • A loop in the DNA forms as the factors interact at the promoter site. • Each factor may also affect other factors. ...
Target selected insertional mutagenesis on chromosome IV of
... Bouchez and Höfte, 1998; Winkler et al., 1998). Although T-DNA insertions are in general single or low copy and stable, an advantage of using transposon- over T-DNA insertions is their ability ...
... Bouchez and Höfte, 1998; Winkler et al., 1998). Although T-DNA insertions are in general single or low copy and stable, an advantage of using transposon- over T-DNA insertions is their ability ...
PPT4 - Ycmou
... Genes located along the DNA are transcribed into RNA that, in the case of mRNA, is then translated into protein at the ribosomes. In other words, DNA determines what proteins and enzymes an organism can synthesize and, therefore, what chemical reactions it is able to carry out. © 2007, YCMOU. Al ...
... Genes located along the DNA are transcribed into RNA that, in the case of mRNA, is then translated into protein at the ribosomes. In other words, DNA determines what proteins and enzymes an organism can synthesize and, therefore, what chemical reactions it is able to carry out. © 2007, YCMOU. Al ...
BIOLOGY SUPPORT MATERIAL
... Internal fertilization –zygote formed inside the body eg. Human beings. Development of zygote depends on type of life cycle and environment. Some develop thick wall ( prevent damage and desiccation) & undergo period of rest eg. Algae, fungi. Haplontic life cycle- zygote (2n) divides by meiosis to fo ...
... Internal fertilization –zygote formed inside the body eg. Human beings. Development of zygote depends on type of life cycle and environment. Some develop thick wall ( prevent damage and desiccation) & undergo period of rest eg. Algae, fungi. Haplontic life cycle- zygote (2n) divides by meiosis to fo ...
Supplementary Legends
... context (i.e. AxA, AxC, AxG, AxT, CxA, CxC, CxG… TxT, where x is the mutated base), with the different colors indicating the mutation type (i.e. C>A, C>G, C>T, T>A, T>C and T>G). The height of colored bars represents the fraction of mutations attributed in each of the 96 sub-bins. (b) Genetic altera ...
... context (i.e. AxA, AxC, AxG, AxT, CxA, CxC, CxG… TxT, where x is the mutated base), with the different colors indicating the mutation type (i.e. C>A, C>G, C>T, T>A, T>C and T>G). The height of colored bars represents the fraction of mutations attributed in each of the 96 sub-bins. (b) Genetic altera ...
Leukaemia Section t(1;14)(p22;q32) in non Hodgkin's lymphoma (NHL) in Oncology and Haematology
... 322 amino acids; contains a caspase recruitment domain; role in the apoptosis. ...
... 322 amino acids; contains a caspase recruitment domain; role in the apoptosis. ...
Mathematical modeling reveals additional links between
... in the redox status triggered by the immune hormone salicylic acid (SA) leads to enhancement rather than perturbation of the TOC1 expression in an NPR1-dependent manner . The stability of the period and the phase to SA perturbation suggest that NPR1 activates other clock genes, in addition to the ev ...
... in the redox status triggered by the immune hormone salicylic acid (SA) leads to enhancement rather than perturbation of the TOC1 expression in an NPR1-dependent manner . The stability of the period and the phase to SA perturbation suggest that NPR1 activates other clock genes, in addition to the ev ...
LECTURE 5: LINKAGE AND GENETIC MAPPING Reading for this
... recombination. Using chromosomes that had cytologically visible abnormalities, Creighton and McClintock working with maize, and Stern, working with Drosophila, showed that recombination depends upon the physical exchange of equal parts between maternal and paternal chromosomes during meiosis. Both g ...
... recombination. Using chromosomes that had cytologically visible abnormalities, Creighton and McClintock working with maize, and Stern, working with Drosophila, showed that recombination depends upon the physical exchange of equal parts between maternal and paternal chromosomes during meiosis. Both g ...
Tissue- and Development-specific Expression of Multiple
... Recently, two alternatively spliced nNOS transcripts arising from two alternative promoters and differing in their 59-untranslated regions (59UTR) have been described in human and murine nNOS genes (17, 18). The use of multiple alternative promoters in conjunction with alternative splicing may repre ...
... Recently, two alternatively spliced nNOS transcripts arising from two alternative promoters and differing in their 59-untranslated regions (59UTR) have been described in human and murine nNOS genes (17, 18). The use of multiple alternative promoters in conjunction with alternative splicing may repre ...
Notch signaling
... •Proviral integration of the Moloney murine-leukaemia virus (MuLV) into the murine Notch1 locus causes T-ALL in mice. •Integration of the mouse mammary tumour virus (MMTV) in between the Notch/Lin12 repeats and the transmembrane domain of either the Notch1 (NI) or Notch4 (N4) gene causes mammary tum ...
... •Proviral integration of the Moloney murine-leukaemia virus (MuLV) into the murine Notch1 locus causes T-ALL in mice. •Integration of the mouse mammary tumour virus (MMTV) in between the Notch/Lin12 repeats and the transmembrane domain of either the Notch1 (NI) or Notch4 (N4) gene causes mammary tum ...
Consultation process for this DIR application
... The parent organisms are wheat (cultivars ‘Bobwhite’, ‘Drysdale’ and ‘Frame’) and barley (cultivars ‘Golden Promise’ and ‘W14330’), which are exotic to Australia. Commercial wheat and barley cultivation occurs in the wheat belt from south eastern Queensland through New South Wales, Victoria, souther ...
... The parent organisms are wheat (cultivars ‘Bobwhite’, ‘Drysdale’ and ‘Frame’) and barley (cultivars ‘Golden Promise’ and ‘W14330’), which are exotic to Australia. Commercial wheat and barley cultivation occurs in the wheat belt from south eastern Queensland through New South Wales, Victoria, souther ...
Hyper-eccentric structural genes in the mitochondrial genome of the
... Three types of RNA editing [i.e., uridine (U) insertion and Ato-I and C-to-U substitutions] are also involved in the mRNA maturation process before the end products of assembled RNA sequences are translated to the proper amino acid sequences (Marande and Burger 2007; Kiethega et al. 2013; Moreira et ...
... Three types of RNA editing [i.e., uridine (U) insertion and Ato-I and C-to-U substitutions] are also involved in the mRNA maturation process before the end products of assembled RNA sequences are translated to the proper amino acid sequences (Marande and Burger 2007; Kiethega et al. 2013; Moreira et ...
Patterns of gene action in plant development revealed by enhancer
... When the element inserts in the proximity of a chromosomal gene, the result is expression of the reporter gene under control of the neighboring chromosomal enhancers. If the insertion is w i t h i n the transcribed region of the gene, a m u t a n t phenotype m a y also be observed in homozygotes. Ge ...
... When the element inserts in the proximity of a chromosomal gene, the result is expression of the reporter gene under control of the neighboring chromosomal enhancers. If the insertion is w i t h i n the transcribed region of the gene, a m u t a n t phenotype m a y also be observed in homozygotes. Ge ...
4 points: Chemistry, Science, Cells
... • All cells come from other cells • Cells are the basic units of structure and function ...
... • All cells come from other cells • Cells are the basic units of structure and function ...
boomsma intro boulder 2008 - Institute for Behavioral Genetics
... unique differences within the monozygotic twin pairs. The number of CNVs identified depends mainly on the settings of the scoring algorithms; in the size range of 0.31.2 Mb we detect 1-2 per pair. CNVs are not present in 100% of the cells. This suggests somatic mosaicism, i.e. a post-meiotic emergen ...
... unique differences within the monozygotic twin pairs. The number of CNVs identified depends mainly on the settings of the scoring algorithms; in the size range of 0.31.2 Mb we detect 1-2 per pair. CNVs are not present in 100% of the cells. This suggests somatic mosaicism, i.e. a post-meiotic emergen ...
The Caenorhabditis elegans NK-2 class
... functions only very weakly (pOK6.22). This analysis suggests the myo-2 enhancer contains several functional components that cooperate to activate transcription. Based on the deletion analysis, we provisionally divided the myo-2 enhancer into three overlapping fragments, designated A, B and C (Fig. 1 ...
... functions only very weakly (pOK6.22). This analysis suggests the myo-2 enhancer contains several functional components that cooperate to activate transcription. Based on the deletion analysis, we provisionally divided the myo-2 enhancer into three overlapping fragments, designated A, B and C (Fig. 1 ...
Document
... Uses one strand of DNA as a template to construct mRNA – adds free-floating nucleotide ...
... Uses one strand of DNA as a template to construct mRNA – adds free-floating nucleotide ...
Appearances can be deceiving: phenotypes of
... written by William Sullivan and Douglas Kellogg on the relative merits of investigating processes using genetic versus biochemical approaches [1]. The analogy, not meant to be taken too seriously, concerns Bill, a retired geneticist, and Doug, a retired biochemist, and their attempts to ascertain ho ...
... written by William Sullivan and Douglas Kellogg on the relative merits of investigating processes using genetic versus biochemical approaches [1]. The analogy, not meant to be taken too seriously, concerns Bill, a retired geneticist, and Doug, a retired biochemist, and their attempts to ascertain ho ...