• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Monooxygenases in the Butane and Cyclohexane Degradation
Monooxygenases in the Butane and Cyclohexane Degradation

... until now. Studies indicated that this enzyme could be related to the soluble butane monooxygenase. The cyclohexane pathway contains a second monooxygenase, type: Baeyer-Villiger monooxygenase (BVO). The sequences of many of these enzymes are published, their sequences are diverse. The enrichment of ...
Frequent and histological type-specific inactivation of 14-3
Frequent and histological type-specific inactivation of 14-3

... (Konishi et al., 2002), which might be attributable to a loss of 14-3-3s expression. The G2 checkpoint defect may lead to chromosomal aberrations, and increase the sensitivity to the DNA damaging events. In this context, it is of interest that SCLC is highly sensitive to irradiation and chemotherape ...
Host protein Snapin interacts with human cytomegalovirus pUL130
Host protein Snapin interacts with human cytomegalovirus pUL130

... pUL130 is a luminal glycoprotein that is inefficiently secreted from infected cells but is incorporated into the virion envelope in a Golgi-matured form (Patrone et al. 2005). The C terminus of pUL130 serves an important function for infection of endothelial cells by HCMV, and mutation of the C-term ...
ArrayExpress and Expression Atlas
ArrayExpress and Expression Atlas

... What is functional genomics (FG)? • The aim of FG is to understand the function of genes and other parts of the genome ...
iBiology Seminar videos with Molecular Biology of the Cell, Sixth
iBiology Seminar videos with Molecular Biology of the Cell, Sixth

... The conversion of DNA to RNA relies on transcription factors (TFs) to recognize the coding sequences and to transcribe the correct genes. Tjian explains how TFs play a massive role in regulating the unique genetic identity of different cell types. (From DNA to RNA) Length: 00:09:49 Transcriptional P ...
FISH
FISH

... Denature the probe Hybridization: The probe will hybridize or bind to its complementary sequences in the cellular DNA Fluorescence staining The bound probe can be visualized under a fluorescent microscope in the nucleus of the cell ...
Temperature-sensitive control of protein activity by conditionally
Temperature-sensitive control of protein activity by conditionally

... Inteins have been described as ‘protein introns’ and function posttranslationally to autonomously splice themselves from within a protein context while regenerating an intact host3–6. Temperaturesensitive splicing variants of the Gyr A and recA inteins have been identified7,8 and such conditional in ...
Full Text  - Genes | Genomes | Genetics
Full Text - Genes | Genomes | Genetics

... heterozygous upSET-deleted flies. Using nascent-RNA sequencing in the upSET-mutant S2 lines, we show that this result applies to heterochromatin genes generally. Our findings support a critical role for UpSET in maintaining heterochromatin, perhaps by delimiting the active chromatin environment. ...
Identification of Four Novel LDL Receptor Gene Mutations in the
Identification of Four Novel LDL Receptor Gene Mutations in the

... detected in the first time in Moroccan population by our group, although it had previously been reported in other populations and is considered not responsible for the disease. DISCUSSION More than 1,000 mutations have been described in the LDLR gene in different populations. 5,6 This gene is compos ...
Fast, simultaneous, and sensitive detection of staphylococci
Fast, simultaneous, and sensitive detection of staphylococci

... new method that is suited to the recovery of extremely small amounts of DNA from Gram positive bacteria. DNA from staphylococci is notoriously difficult to isolate because of the membrane structure of these organisms.4 We have shown that lysis in an SDS/β mercaptoethanol buffer and exposure to micro ...
The Discovery and Significance of Selected Blood Groups
The Discovery and Significance of Selected Blood Groups

... was made to expose the blood vessels before they could be connected―a difficult and messy affair. • His gravitator allowed blood to be transferred from donor to patient without the need for surgical exposure of the blood vessels so that the donor’s and patient’s blood vessels could be used repeatedl ...
Document
Document

... What if UAG was placed instead of CAG ...
The knockout of miR-143 and -145 alters smooth muscle cell
The knockout of miR-143 and -145 alters smooth muscle cell

... (transverse aortic constriction and in aortas of the ApoE KO mouse). In human aortic aneurysms, the expression of miR-143 and -145 was significantly decreased compared with control aortas. In addition, overexpression of miR-143 and -145 decreased neointimal formation in a rat model of acute vascular ...
Genetic polymorphisms of T-1131C APOA5 and ALOX5AP
Genetic polymorphisms of T-1131C APOA5 and ALOX5AP

... populations worldwide. The mechanism by which this polymorphism could induce IS is that, it can affect the function of transcription of the protein which secondarily causes a change in the synergistic APOA5 with lipoprotein lipase, the main enzyme involved in circulating triglycerides regulation (Pe ...
Characterization of the trans-spliced transcriptome and polycistronic
Characterization of the trans-spliced transcriptome and polycistronic

... Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK ...
Controlling morpholino experiments: don`t stop making antisense
Controlling morpholino experiments: don`t stop making antisense

... done successfully using RNAi in C. elegans embryos (Gonczy et al., 2000; Kamath et al., 2003; Sonnichsen et al., 2005) and in tissue culture cells in D. melanogaster (Agaisse et al., 2005; Boutros et al., 2004; Friedman and Perrimon, 2006). This study (Rana et al., 2006) also showed that fluorescent ...
Text S1.
Text S1.

... with this position now occupied by sponges (BS=80%), and Placozoa are now sistergroup to Bilateria (BS=61%). In other words, merely using a close outgroup is enough to make the analysis of the Schierwater et al. dataset congruent with the topology of Philippe et al. [4]. It is noteworthy that the se ...
Review of BASIC transmission genetics
Review of BASIC transmission genetics

... “Factors” are genes. The purpose of the two factor cross is usually to determine map distance between two genes. The cross used is a type of testcross. The mapping testcross is always a heterozygote crossed to a recessive homozygous tester. Example of a 2 factor cross: ...
Distinct Contributions of Replication and Transcription to Mutation
Distinct Contributions of Replication and Transcription to Mutation

... suggested to have a weaker effect on the global variation of mutation rate, we noticed, however, when examining HK genes, that transcription-associated mutation pressure mainly affected the highly-expressed genes. We noted that SNP density was actually positively correlated with expression level amo ...
biopatt - Carnegie Mellon School of Computer Science
biopatt - Carnegie Mellon School of Computer Science

... Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the World Wide Web in the UK,…, Sweden, …, France, …, US. The latest version (6.6) of Pfam contains 3071 families, which match 69% of proteins in SWISS-PROT 39 and TrEMBL 14. Str ...
Can you tell if any of these animals are transgenic?
Can you tell if any of these animals are transgenic?

... What’s in a Gene? The function of most genes is to produce or express a protein. Some proteins become part of a cell’s structure and others help regulate a cell’s processes. In making proteins, different parts of the gene perform different functions (see diagram). A coding section contains the instr ...
NARRATOR: Pembrey was stunned. Angelman syndrome and
NARRATOR: Pembrey was stunned. Angelman syndrome and

... light switch. Switch on the gene, the light is shining, the gene is active... makes the cell do a certain thing. Or the light switch is off, everything is dark. That gene is off. And as the cells divide, the memory of whether it's a liver cell or a brain cell, that's brought about by these switches. ...
CHAPTER 1
CHAPTER 1

... amino acid sequence per se, but rather is imparted from without during synthesis, then the refolding would be random and only a few percent of the refolded molecule would happen upon the correct solution to the cysteine pairing problem. In the first case, full enzyme activity is restored by refoldin ...
Answer Appendix B - McGraw Hill Higher Education
Answer Appendix B - McGraw Hill Higher Education

... E2. This would be used primarily by molecular geneticists. The sequence of DNA is a molecular characteristic of DNA. In addition, as we will learn throughout this textbook, the sequence of DNA is interesting to transmission and population geneticists as well. E4. A. Transmission geneticists. Dog bre ...
Meiotic markers of gonad development in zebrafish
Meiotic markers of gonad development in zebrafish

... atm is associated with sites along the synaptonemal complex which are thought to be involved in meiotic recombination. (Plug AW et al., 1997) ...
< 1 ... 241 242 243 244 245 246 247 248 249 ... 1045 >

Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report