Evolutionary Origin of Recombination during Meiosis
... exogenous DNA from the surrounding medium followed by integration—was probably the ancestral function. In the next section, we present evidence that RecA orthologs have a central role in meiotic recombination. Recombinational repair is not limited to transformation in bacteria or meiosis in eukaryot ...
... exogenous DNA from the surrounding medium followed by integration—was probably the ancestral function. In the next section, we present evidence that RecA orthologs have a central role in meiotic recombination. Recombinational repair is not limited to transformation in bacteria or meiosis in eukaryot ...
REPORT C-Terminal Deletions in the ALAS2 Gene Lead to Gain of
... iron-dependent post-transcriptional regulation of synthesis of ALAS2.2 This system fails in XLDPP because the mutations that we have described greatly increase ALAS2 activity. A possible mechanism might be stabilization against degradation or an intrinsic increase in specific activity. This C-termina ...
... iron-dependent post-transcriptional regulation of synthesis of ALAS2.2 This system fails in XLDPP because the mutations that we have described greatly increase ALAS2 activity. A possible mechanism might be stabilization against degradation or an intrinsic increase in specific activity. This C-termina ...
A global view of pleiotropy and phenotypically derived gene function
... retardation and blood coagulation abnormalities of Type 1b congenital disorders of glycosylation, and DNA damage repair protein NBS1 mutations that lead to microcephaly, immunodeficiency, and cancer predisposition in Nijmegen breakage syndrome (http://www.ncbi.nlm.nih.gov/omim/). A major challenge in ...
... retardation and blood coagulation abnormalities of Type 1b congenital disorders of glycosylation, and DNA damage repair protein NBS1 mutations that lead to microcephaly, immunodeficiency, and cancer predisposition in Nijmegen breakage syndrome (http://www.ncbi.nlm.nih.gov/omim/). A major challenge in ...
II. Purpose of Meiosis #1
... This outline is the same as is found in your Lecture Guide. In order to obtain an overview of the material in the Lecture Guide and to be able to see the ‘big’ picture while you study, fill in the missing components of the following outline from the Lecture Guide. ...
... This outline is the same as is found in your Lecture Guide. In order to obtain an overview of the material in the Lecture Guide and to be able to see the ‘big’ picture while you study, fill in the missing components of the following outline from the Lecture Guide. ...
Applied and Environmental Microbiology
... Archaeoglobus fulgidus (16). Form IV is designated a RubisCOlike protein, as its sequence is most closely related to RubisCO but it is not involved in the Calvin cycle. The large subunit of form I RubisCO is encoded by the cbbL gene (18). The cbbL gene is 1,400 bp long and thus is large enough for u ...
... Archaeoglobus fulgidus (16). Form IV is designated a RubisCOlike protein, as its sequence is most closely related to RubisCO but it is not involved in the Calvin cycle. The large subunit of form I RubisCO is encoded by the cbbL gene (18). The cbbL gene is 1,400 bp long and thus is large enough for u ...
Prioritizing curation of mouse genes by paucity of annotations and
... experimental data by mid 2015. Based on our early results, we were able to annotate some genes that were not associated in the Mouse Genome Database (MGD) with literature tagged to be curated for Gene Ontology. In some cases, this was due to publication of new papers after acquisition of the initial ...
... experimental data by mid 2015. Based on our early results, we were able to annotate some genes that were not associated in the Mouse Genome Database (MGD) with literature tagged to be curated for Gene Ontology. In some cases, this was due to publication of new papers after acquisition of the initial ...
Introduction and Preliminaries - Department of Computer and
... Consists of a DNA molecule associated with proteins that fold and pack the DNA thread into a more compact structure and proteins required for the process of gene expression, DNA replication and DNA repair. Human genome is distributed over 24 chromosomes ...
... Consists of a DNA molecule associated with proteins that fold and pack the DNA thread into a more compact structure and proteins required for the process of gene expression, DNA replication and DNA repair. Human genome is distributed over 24 chromosomes ...
functional analysis of chromatin assembly genes in tetrahymena
... Fillingham for providing me with an exceptional opportunity to grow and gain knowledge in the field of molecular biology under his supportive guidance. I am also extremely thankful to Dr.Jyoti Garg who provided me with exceptional insights and assistance throughout the depth of my thesis. I would li ...
... Fillingham for providing me with an exceptional opportunity to grow and gain knowledge in the field of molecular biology under his supportive guidance. I am also extremely thankful to Dr.Jyoti Garg who provided me with exceptional insights and assistance throughout the depth of my thesis. I would li ...
ppt - Chair of Computational Biology
... The random results were obtained as follows. The predictions of the network were scrambled and assigned randomly to the residues in the test set. Then the filtering stage was applied to these `predictions', to reveal any size effect that might result from the distributions of the contacts and the pr ...
... The random results were obtained as follows. The predictions of the network were scrambled and assigned randomly to the residues in the test set. Then the filtering stage was applied to these `predictions', to reveal any size effect that might result from the distributions of the contacts and the pr ...
Supplementary Materials and Methods (doc 45K)
... of pure ethanol per day. This amount, in the same range as those reported in previous studies in single housed C57BL/6J mice having free access to ethanol under the very same conditions as those used in our own study (see3,4), is sufficient to yield blood ethanol levels near 50-70 mg/100 mL during t ...
... of pure ethanol per day. This amount, in the same range as those reported in previous studies in single housed C57BL/6J mice having free access to ethanol under the very same conditions as those used in our own study (see3,4), is sufficient to yield blood ethanol levels near 50-70 mg/100 mL during t ...
Pearson science 10 Teaching Program 3–4 weeks Chapter 1 DNA
... In this chapter, students will learn about DNA and be able to describe its role in controlling the characteristics of organisms. They will use models and diagrams to represent relationships between DNA, genes and chromosomes. They will be able to explain the role of meiosis and fertilisation in the ...
... In this chapter, students will learn about DNA and be able to describe its role in controlling the characteristics of organisms. They will use models and diagrams to represent relationships between DNA, genes and chromosomes. They will be able to explain the role of meiosis and fertilisation in the ...
The epigenetic basis of gender in flowering plants and mammals
... biallelic expression of imprinted growth promoters, or deletion of imprinted genes involved in growth inhibition or apoptosis, occur in many cancers, both hereditary and sporadic (reviewed in Refs 20,21). Overexpression of Igf2 occurs in a wide variety of cancers, suggesting a correlation of paterna ...
... biallelic expression of imprinted growth promoters, or deletion of imprinted genes involved in growth inhibition or apoptosis, occur in many cancers, both hereditary and sporadic (reviewed in Refs 20,21). Overexpression of Igf2 occurs in a wide variety of cancers, suggesting a correlation of paterna ...
Inheritance of Nuclear DNA Markers in Gynogenetic Haploid Pink
... amplification product) since recessive alleles are not obscured by their dominant alternatives ( Lie et al. 1994). Haploid embryos are not viable; however, they do develop until just prior to hatching (Stanley 1983), providing an embryo from which a sufficient quantity of DNA can be isolated to comp ...
... amplification product) since recessive alleles are not obscured by their dominant alternatives ( Lie et al. 1994). Haploid embryos are not viable; however, they do develop until just prior to hatching (Stanley 1983), providing an embryo from which a sufficient quantity of DNA can be isolated to comp ...
22 August 2002
... the chimpanzee and orang-utan do not differ at any polymorphic position compared with humans, we assumed no back mutations when estimating the P value for H. The likelihood ratio tests for non-silent and silent substitutions were performed using the PAML package12 as described25 (see Supplementary I ...
... the chimpanzee and orang-utan do not differ at any polymorphic position compared with humans, we assumed no back mutations when estimating the P value for H. The likelihood ratio tests for non-silent and silent substitutions were performed using the PAML package12 as described25 (see Supplementary I ...
A novel mutation of the Keratin 12 gene responsible for a severe
... either helix-initiation or helix-termination motif [8-17]. The motifs were highly conserved among keratin proteins, and the domains are important in intermediate filament assembly and are likely involved in mediating end-to-end interactions between keratin heterodimers. Interestingly, there were mor ...
... either helix-initiation or helix-termination motif [8-17]. The motifs were highly conserved among keratin proteins, and the domains are important in intermediate filament assembly and are likely involved in mediating end-to-end interactions between keratin heterodimers. Interestingly, there were mor ...
comparing quantitative trait loci and gene expression data
... adopted the embedded conversion tool in Expressionview (Fischer et al, 2003) to estimate physical distances from cM. The “smoothing window” technique used in Expressionview essentially applies the idea of piecewise regression. However at the edge of chromosomes and some middle places where possibly ...
... adopted the embedded conversion tool in Expressionview (Fischer et al, 2003) to estimate physical distances from cM. The “smoothing window” technique used in Expressionview essentially applies the idea of piecewise regression. However at the edge of chromosomes and some middle places where possibly ...
The R2R3 MYB Transcription Factor GhMYB109 Is
... induces a single trichome from the epidermis of Arabidopsis seeds (Wang et al. 2004b). GhMYB25, a homolog of AmmIXTA/AmmYBML1 that controls petal conical cell and trichome differentiation in Antirrhinum majus, is predominately expressed in ovules and fiber cell initials (Wu et al. 2006). A recent wo ...
... induces a single trichome from the epidermis of Arabidopsis seeds (Wang et al. 2004b). GhMYB25, a homolog of AmmIXTA/AmmYBML1 that controls petal conical cell and trichome differentiation in Antirrhinum majus, is predominately expressed in ovules and fiber cell initials (Wu et al. 2006). A recent wo ...
Morphogenesis of Flowers—Our Evolving View
... about plant sexual reproduction. The closest they got was to realize that there are two forms of date palm and that fruit set could be promoted if dust of a flowering shoot of a sterile tree was shaken over the flowering shoots of potentially fertile trees. The first historical records of attempts t ...
... about plant sexual reproduction. The closest they got was to realize that there are two forms of date palm and that fruit set could be promoted if dust of a flowering shoot of a sterile tree was shaken over the flowering shoots of potentially fertile trees. The first historical records of attempts t ...
SNP Analysis of the PTC Gene Using PCR
... Four nucleotide letters specify the genetic code: A (Adenine), C (Cytosine), T (Thymine), and G (Guanine). A point mutation occurs when one nucleotide is replaced by another nucleotide. For example when an A is replaced by a C, T or G (Figure 1). When such a mutation is present in at least 1% of the ...
... Four nucleotide letters specify the genetic code: A (Adenine), C (Cytosine), T (Thymine), and G (Guanine). A point mutation occurs when one nucleotide is replaced by another nucleotide. For example when an A is replaced by a C, T or G (Figure 1). When such a mutation is present in at least 1% of the ...
Descriptors for genetic markers technologies
... Carmen de Vicente, Dr Thomas Metz and Ms Adriana Alercia in an effort attempt to define community standards for documenting information about genetic markers. This document is targeted to researchers using genetic marker technologies to generate and exchange genetic marker data that are standardized ...
... Carmen de Vicente, Dr Thomas Metz and Ms Adriana Alercia in an effort attempt to define community standards for documenting information about genetic markers. This document is targeted to researchers using genetic marker technologies to generate and exchange genetic marker data that are standardized ...
Multiple Domains Exist within the Upstream Activator
... UAS. The activity of the pSau133 fragment is equivalent to that of the larger element (pENl), whereas the activity of the pAlulO6 fragment is greater (Figure 3). One possible interpretation of these data is that inhibitory sequences are located between the Alul and Sau3a sites. Interestingly, pAIRa4 ...
... UAS. The activity of the pSau133 fragment is equivalent to that of the larger element (pENl), whereas the activity of the pAlulO6 fragment is greater (Figure 3). One possible interpretation of these data is that inhibitory sequences are located between the Alul and Sau3a sites. Interestingly, pAIRa4 ...
Molecualr Biology and Evolution
... lished procedures (Sambrook et al. 1989). Total DNA ( 1) that the crucial branches on the nifH tree are not from Frankia strain HFPCcI3 was isolated as described defined unambiguously; (2) that if the Clostridium n$H previously (Reddy et al. 1992). The DNA was digested is paralogous to the other n&H ...
... lished procedures (Sambrook et al. 1989). Total DNA ( 1) that the crucial branches on the nifH tree are not from Frankia strain HFPCcI3 was isolated as described defined unambiguously; (2) that if the Clostridium n$H previously (Reddy et al. 1992). The DNA was digested is paralogous to the other n&H ...
Quantitative genetics of gene expression during fruit fly - EMBL-EBI
... of individuals. More recently, the GWAS approach has also been applied to highthroughput RNA sequencing (RNA-seq) data in order to find loci associated with different levels of gene expression, called expression quantitative trait loci (eQTL). Because of the large amount of data that is required for ...
... of individuals. More recently, the GWAS approach has also been applied to highthroughput RNA sequencing (RNA-seq) data in order to find loci associated with different levels of gene expression, called expression quantitative trait loci (eQTL). Because of the large amount of data that is required for ...
First Pass Comments from Eric Stavney 10/29/03
... [Andy 10/29: Add the title “Lac Operon” to the 1st exercise. This is the one with the clickable chromosome. Also in this exercise, the first popup is missing a period in the last sentence OR the rest of the sentence is missing. Please correct.] 7. In 16.1.8.3 the feedback text that comes up to the r ...
... [Andy 10/29: Add the title “Lac Operon” to the 1st exercise. This is the one with the clickable chromosome. Also in this exercise, the first popup is missing a period in the last sentence OR the rest of the sentence is missing. Please correct.] 7. In 16.1.8.3 the feedback text that comes up to the r ...
Evolutionary Origin and Adaptive Function of Meiosis
... A DNA damage is an alteration in the molecular structure of DNA, such as a break in one or both DNA strands, a missing base, or an oxidized base (e.g. 8-OHdG). Damage to DNA often results from natural processes. As noted by Haynes (1988), DNA is comprised of rather ordinary molecular subunits that a ...
... A DNA damage is an alteration in the molecular structure of DNA, such as a break in one or both DNA strands, a missing base, or an oxidized base (e.g. 8-OHdG). Damage to DNA often results from natural processes. As noted by Haynes (1988), DNA is comprised of rather ordinary molecular subunits that a ...