New Perspectives on Rickettsial Evolution from New
... among these species or to other bacteria. This contrasts with the strong chromosome synteny and high gene homology of most well-identified functional proteins as described below; consequently, the reliability of ORF identification appears to decrease with increased genome size and many of these pred ...
... among these species or to other bacteria. This contrasts with the strong chromosome synteny and high gene homology of most well-identified functional proteins as described below; consequently, the reliability of ORF identification appears to decrease with increased genome size and many of these pred ...
early RNs, crossing over initiates, then synapsis begins Chiasmata
... • Large nested retrotransposon blocks (~50% of maize genome) is recombinationally inactive – even when in homozygous state. Also highly methylated. • Perhaps 2 levels of control – chromatin state (exposed chromosome regions more easily accessed by enzymes) plus sequence similarity. ...
... • Large nested retrotransposon blocks (~50% of maize genome) is recombinationally inactive – even when in homozygous state. Also highly methylated. • Perhaps 2 levels of control – chromatin state (exposed chromosome regions more easily accessed by enzymes) plus sequence similarity. ...
FEMS Microbiology Ecology
... when data were analyzed at the strain level by detrended correspondence analysis. Further, a profile clustering network revealed strain-specific abundance shifts among Acidobacteria and other bacteria. Study of stability and change in host-associated bacterial communities requires a fine-grained ana ...
... when data were analyzed at the strain level by detrended correspondence analysis. Further, a profile clustering network revealed strain-specific abundance shifts among Acidobacteria and other bacteria. Study of stability and change in host-associated bacterial communities requires a fine-grained ana ...
Document
... $ tophat –p 4 –o ctrl chr22 thrombin_control.txt # Run TopHAT using chr22 as reference and sequences in the control. # -p indicates the number of cpus (4). # -o indicates the output directory (ctrl). ...
... $ tophat –p 4 –o ctrl chr22 thrombin_control.txt # Run TopHAT using chr22 as reference and sequences in the control. # -p indicates the number of cpus (4). # -o indicates the output directory (ctrl). ...
Mutator Transposon in Maize and MULEs in the Plant Genome
... mutations, germinally transmitted revertants are extremely rare in Mutator lines, which suggest that excisions are prevented by some kind of mechanism in cells that give rise to gametes[21]. In minimal Mutator lines with just one copy of Mu1 initially inserted into the a1-mum2 allele and one copy of ...
... mutations, germinally transmitted revertants are extremely rare in Mutator lines, which suggest that excisions are prevented by some kind of mechanism in cells that give rise to gametes[21]. In minimal Mutator lines with just one copy of Mu1 initially inserted into the a1-mum2 allele and one copy of ...
Cloning of genes from genomic DNA: Part 3
... Why does each oligonucleotide primer (each end of the PCR product) have a different restriction enzyme site? To keep it simple, we could have just put an XbaI site on each primer. Then, we would cut both the PCR product and the plasmid with only XbaI. However, by this method, the PCR product can be ...
... Why does each oligonucleotide primer (each end of the PCR product) have a different restriction enzyme site? To keep it simple, we could have just put an XbaI site on each primer. Then, we would cut both the PCR product and the plasmid with only XbaI. However, by this method, the PCR product can be ...
Daisy quorum drives for the genetic restoration of wild
... depriving subsequent elements of their inheritance advantage9. In daisyfield drive systems, many daisy elements all target the same allele and cause it to drive; their number decreases by half with every generation of mating with wild-type organisms until none are left and drive ceases10. By enablin ...
... depriving subsequent elements of their inheritance advantage9. In daisyfield drive systems, many daisy elements all target the same allele and cause it to drive; their number decreases by half with every generation of mating with wild-type organisms until none are left and drive ceases10. By enablin ...
Chromosomal rearrangements maintain a
... Michael A. Quail9, Helen Beasley9, Rebecca Glithero9, Christine Lloyd9, Sarah Sims9, Matthew C. Jones9, Jane Rogers9, Chris D. Jiggins7 & Richard H. ffrench-Constant4 ...
... Michael A. Quail9, Helen Beasley9, Rebecca Glithero9, Christine Lloyd9, Sarah Sims9, Matthew C. Jones9, Jane Rogers9, Chris D. Jiggins7 & Richard H. ffrench-Constant4 ...
... by Cm-PL-3 and Cm-PL-10 was detected 48 h post inoculation, for Cg-14 and L-2.5 only after 120 h (Fig. 4B). Inoculation of watermelon seedlings with Cm-PL-10 and Cm-PL-3 caused damping off and leaf necrosis, whereas no symptoms developed with the two wild-type isolates Cg-14 and L-2.5, 6 days post i ...
ZFIN-Mar2006 - Gene Ontology Consortium
... project management / development activities and literature curation for all data types, including GO. As a result, only a fraction of each curator’s time is spent on GO curation. To promote correct GO annotation we have frequent discussions and we all read the GO Annotation email list. I (Doug) have ...
... project management / development activities and literature curation for all data types, including GO. As a result, only a fraction of each curator’s time is spent on GO curation. To promote correct GO annotation we have frequent discussions and we all read the GO Annotation email list. I (Doug) have ...
Protecting Against Rod Degeneration In A Model Of Retinitis
... Retinitis Pigmentosa (RP) is a heritable disease that affects the retina, the photosensitive neural tissue lining the back of the eye. RP results in the gradual degeneration of rod photoreceptor cells, but secondarily cone cells degenerate and all visual input is lost. Mutations in nearly 100 genes ...
... Retinitis Pigmentosa (RP) is a heritable disease that affects the retina, the photosensitive neural tissue lining the back of the eye. RP results in the gradual degeneration of rod photoreceptor cells, but secondarily cone cells degenerate and all visual input is lost. Mutations in nearly 100 genes ...
Signal Transduction and the Chemically Addressed Nervous System
... unique brain chemicals. In this book, however, only a half dozen or so particular neurotransmitters are emphasized, because psychotropic drugs utilized in clinical practice act largely on serotonin, norepinephrine, and dopamine as well as acetylcholine, glutamate, and GABA (gamma-aminobutyric acid). ...
... unique brain chemicals. In this book, however, only a half dozen or so particular neurotransmitters are emphasized, because psychotropic drugs utilized in clinical practice act largely on serotonin, norepinephrine, and dopamine as well as acetylcholine, glutamate, and GABA (gamma-aminobutyric acid). ...
Mouse genetics provides insight into folliculogenesis, fertilization
... These germ-line syncytia undergo a developmentally programmed breakdown associated with invasion of pre-granulosa cells just prior to primordial follicle formation (Pepling and Spradling, 2001). In the neonatal ovary, each surviving dictyate oocyte is enclosed in a layer of ¯attened pre-granulosa ce ...
... These germ-line syncytia undergo a developmentally programmed breakdown associated with invasion of pre-granulosa cells just prior to primordial follicle formation (Pepling and Spradling, 2001). In the neonatal ovary, each surviving dictyate oocyte is enclosed in a layer of ¯attened pre-granulosa ce ...
Yeast whole-genome analysis of conserved regulatory motifs
... • Enhancer networks: Regulator enhancer target gene • Ex1: Oct4 predicted activator of embryonic stem (ES) cells • Ex2: Gfi1 repressor of K562/GM cells ...
... • Enhancer networks: Regulator enhancer target gene • Ex1: Oct4 predicted activator of embryonic stem (ES) cells • Ex2: Gfi1 repressor of K562/GM cells ...
CHAPTER 1 Introduction
... We analyzed hox gene expression in embryos without organisers or without non organizer mesoderm and in heterochronic organiser transplant experiments into ventralised embryos, containing only non organizer mesoderm, These experiments showed that the A-P pattern is generated in the non-organiser meso ...
... We analyzed hox gene expression in embryos without organisers or without non organizer mesoderm and in heterochronic organiser transplant experiments into ventralised embryos, containing only non organizer mesoderm, These experiments showed that the A-P pattern is generated in the non-organiser meso ...
Selection for TnlO Tet Repressor Binding to tet Operator
... Tet repressor protein with a total length of 207 amino acid residues is represented by a linear bar with both the N- and C-terminal ends indicated. The solid portion defines the potential a-helix-turn-ahelix motif, which is thought to be involved in DNA binding (amino acid residues 26 to 47; ISACKSO ...
... Tet repressor protein with a total length of 207 amino acid residues is represented by a linear bar with both the N- and C-terminal ends indicated. The solid portion defines the potential a-helix-turn-ahelix motif, which is thought to be involved in DNA binding (amino acid residues 26 to 47; ISACKSO ...
Soybean proteins GmTic110 and GmPsbP are crucial for chloroplast
... plants showed significant reduction of chlorophyll a and b. Photochemical energy conversion efficiency and photochemical reflectance index were reduced in the viable-yellow plants relative to the wildtype, whereas the lethal-yellow plants showed no electron transport activity. The viable-yellow plants ...
... plants showed significant reduction of chlorophyll a and b. Photochemical energy conversion efficiency and photochemical reflectance index were reduced in the viable-yellow plants relative to the wildtype, whereas the lethal-yellow plants showed no electron transport activity. The viable-yellow plants ...
BAP1 Presentation
... Reversed effects of increased histone 2A ubiquitylation in BAP1-deficient uveal melanoma tumor cells; also reduced growth of UM xenografts (Landreville et al. 2012) In a Phase I trial, four (30%) of 13 patients with malignant pleural mesothelioma that received vorinostat had a stabilization of their ...
... Reversed effects of increased histone 2A ubiquitylation in BAP1-deficient uveal melanoma tumor cells; also reduced growth of UM xenografts (Landreville et al. 2012) In a Phase I trial, four (30%) of 13 patients with malignant pleural mesothelioma that received vorinostat had a stabilization of their ...
Archives of Microbiology
... of the VnfDG products are altered by this gene fusion, nor whether the unique addition of 21 nucleotides in the vnfDG fusion area of Anabaena sp. CH1 is of functional signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to thos ...
... of the VnfDG products are altered by this gene fusion, nor whether the unique addition of 21 nucleotides in the vnfDG fusion area of Anabaena sp. CH1 is of functional signiWcance. In a neighbor-joining analysis of all available deduced VnfDG sequences, those from cyanobacteria clustered next to thos ...
About the origin and development of hereditary
... by the translocation breakpoints. In order to investigate the genetic origin and features of the CRCC tumors that occurred in this family, we have extended the pedigree up to four generations, and analyzed peripheral blood samples from 36 members, CRCC tumors, normal renal tissues, and a gastric tum ...
... by the translocation breakpoints. In order to investigate the genetic origin and features of the CRCC tumors that occurred in this family, we have extended the pedigree up to four generations, and analyzed peripheral blood samples from 36 members, CRCC tumors, normal renal tissues, and a gastric tum ...
A familial inverted duplication/deletion of 2p25.1–25.3
... re-defined by real-time PCR and breakpoint cloning, demonstrating the presence of a 2680 bp single-copy sequence between deleted and duplicated regions and the involvement of a simple repeat with the potential for forming a non-B DNA structure. The rearrangement was not mediated by segmental duplica ...
... re-defined by real-time PCR and breakpoint cloning, demonstrating the presence of a 2680 bp single-copy sequence between deleted and duplicated regions and the involvement of a simple repeat with the potential for forming a non-B DNA structure. The rearrangement was not mediated by segmental duplica ...
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract
... access to text, natural language processing, and information integration. Developers of text mining applications often look for appropriate ontologies that can be integrated into their systems, rather than develop new ontologies from scratch. The choice of ontology may, however, have a major impact ...
... access to text, natural language processing, and information integration. Developers of text mining applications often look for appropriate ontologies that can be integrated into their systems, rather than develop new ontologies from scratch. The choice of ontology may, however, have a major impact ...
Considerations for Analyzing Targeted NGS Data – HLA
... Lots of similar genes and lots of very similar pseudegenes. Duplicated segments can be more similar to each other within an individual than they are similar to the corresponding segments of the reference genome. ...
... Lots of similar genes and lots of very similar pseudegenes. Duplicated segments can be more similar to each other within an individual than they are similar to the corresponding segments of the reference genome. ...
Neuroendocrine Gene Regulation in Hypothalamic Cell Lines
... more DNA sequences that transcription factors can bind to, resulting in an increase or decrease in transcriptional activity [22]. Enhancer and silencer regions are short DNA sequences that can be found thousands of base pairs upstream, downstream or even within the gene they control. These DNA motif ...
... more DNA sequences that transcription factors can bind to, resulting in an increase or decrease in transcriptional activity [22]. Enhancer and silencer regions are short DNA sequences that can be found thousands of base pairs upstream, downstream or even within the gene they control. These DNA motif ...
DNA -‐ Compsci 201
... The code in the class DNABenchMark can be used to benchmark the cutAndSplice method. The code given to you will pop-‐up a file-‐dialog box — when run you can use this to nav ...
... The code in the class DNABenchMark can be used to benchmark the cutAndSplice method. The code given to you will pop-‐up a file-‐dialog box — when run you can use this to nav ...