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Correlation of ABCA4 polymorphisms with age
Correlation of ABCA4 polymorphisms with age

... Abstract: Aims: This research aimed to explore the correlation of ATP-binding cassette, sub-family A, member 4 (ABCA4) gene polymorphisms (rs560426 and 6389T>A) with the occurrence of age-related macular degeneration (AMD). Methods: Polymerase chain reaction-restriction fragment length polymorphism ...
Lab 1 Scientific Experimentation: Standard Curve Analysis
Lab 1 Scientific Experimentation: Standard Curve Analysis

... that humans can find things out directly from experience without having to depend on other humans (or books, etc.) for knowledge, and that the rules that are deduced can be used to make predictions about the outcome of future events so we can plan effective actions. Scientists write down the conclus ...
Understanding Our Environment
Understanding Our Environment

... Tumors From Viral Infection ...
Genetic Diversity of Rhizobium leguminosarum as Revealed
Genetic Diversity of Rhizobium leguminosarum as Revealed

... isolates from lower delta locations (Cairo, Quesna and Al-Dakahlia) formed one group in addition to isolate from Beni Suef which is about 224 kilometer (Km) from Al-Dakahlia. On the other hand, the grouping pattern of the remaining isolates was rather puzzling. Isolates from Zefta and South Sinai fo ...
Leukaemia Section t(9;22)(q34;q11) in CML Atlas of Genetics and Cytogenetics
Leukaemia Section t(9;22)(q34;q11) in CML Atlas of Genetics and Cytogenetics

... be associated with progression into blast crisis. B- Correlations between molecular pathways and leukemic phenotype observed in primary CML cells or in BCR-ABL-transduced cells are currently limited. ...
Lophotrochozoan relationships and parasites. A snap-shot
Lophotrochozoan relationships and parasites. A snap-shot

... through morphological characters – has often been not recovered for these taxa (e.g. Bleidorn et al., 2003). Some researchers consider molluscs closely related to annelids (e.g. Nielsen, 2001) – a hypothesis which is congruent with recent phylogenomic analyses (Baurain et al., 2007, Philippe et al., ...
Quantitative and Single-Gene Perspectives on the Study of Behavior
Quantitative and Single-Gene Perspectives on the Study of Behavior

... mutagenesis was later applied to more complex multicellular phenotypes such as embryonic pattern formation (Nusslein-Volhard & Wieschaus 1980). [Recent, genome-level analysis suggests that saturation mutagenesis is actually quite difficult to achieve in practice (cf. Giaever et al. 2002).] As first ...
Epistemic goal as aspect of meaning
Epistemic goal as aspect of meaning

... cases where an epistemic goal can be tied to a single central concept, in that the rationale for the introduction and continued use of this theoretical term is to pursue the epistemic goal in question. A biological term may be used to arrive at certain types of explanations (e.g. the explanation of ...
Identification and characterisation of Bacillus subtilis as cellulase
Identification and characterisation of Bacillus subtilis as cellulase

... would imply multiple cellulase activities including exoglucanase activities because these enzymes work in crystalline regions (Dashtban et al. 2010). ...
In Vitro Cell. Dev. Biol. In Press
In Vitro Cell. Dev. Biol. In Press

... regenerated shoots after transfer to regeneration medium. On 2 mg l21 PPT or kanamycin (100 mg l21) and 300 mg l21 cefotaxime small shoots began to develop. In PPT-containing medium, shoots died after 10 d of culture due to their sensitivity. However, continued culture in the same medium resulted in ...
Analysis of genetic structure in Slovak Pinzgau cattle using five
Analysis of genetic structure in Slovak Pinzgau cattle using five

... ARORA et al., 2010). Analysis of milk proteins polymorphism provides useful information to both the breeders and processors of milk. Many research reports have indicated that certain milk protein variants may be associated with milk production, milk composition (ROBITAILLE et al., 2002) and cheese p ...
Supplemental Table 1 and Figure Legends
Supplemental Table 1 and Figure Legends

... Eulero-Venn diagrams highlighting the numbers of common and exclusive genes detected in samples derived from 200 MCF7 cells spiked into healthy donor blood (HDB); from HDB not treated with AdnaWash buffer and HDB samples treated with AdnaWash buffer. Gene Ontologies for exclusive genes in each set a ...
Calcitonin
Calcitonin

... contain
a
large
N
Terminal
Extracellular
Domain
(ECD),
3
extracellular
loops
(ECL
1,2,3),
7
 transmembrane
domains,
3
intracellular
loops
(ICl
1,2,3)
and
an
intracellular
C
terminus
(Barwell
et.
all
 3).

“The
concept
that
most
simply
encapsulates
the
mode
of
ligand
binding
and
activation
of
family
 ...
S010
S010

... microRNAs. Here, one transcript may be processed to produce multiple functional microRNA sequences. In addition, each microRNA precursor hairpin has the potential to produce two different mature microRNAs. We have investigated the evolutionary and functional relationships between the multiple produc ...
T-box-mediated control of the anabolic proline biosynthetic genes of
T-box-mediated control of the anabolic proline biosynthetic genes of

... (Gotsche & Dahl, 1995). TreA enzyme activity is expressed as U (mg protein)21 according to the definition used for the quantification of b-galactosidase (Miller, 1992). Protein concentrations of the samples were estimated from the optical density of the cell culture. In each of the proB–treA fusion ...
Ernest Just - CPO Science
Ernest Just - CPO Science

... monasteries were centers of learning. The monastery suited Mendel well. It was here that he conducted his famous pea experiments. Mendel’s approach to explaining his results was unique. He used math to defend what occurred naturally. This was a novel approach in the field of biology. He started his ...
Insights into three whole-genome duplications gleaned
Insights into three whole-genome duplications gleaned

... With the discovery of at least three successive whole-genome duplications (WGDs) in the history of the P. tetraurelia lineage (AURY et al. 2006), there is renewed interest in the evolution and genetics of Paramecium. WGDs can be found in the ancestry of many model organisms, including zebrafish (POS ...
Question paper - Unit F215 - Control, genomes and
Question paper - Unit F215 - Control, genomes and

... (c) One effect of thyroid hormones is to increase the activity of mitochondria within cells. Suggest how the metabolism of a person with the condition congenital hypothyroidism might differ from that of a person who does not have this condition. ...
Ribosomal frameshifting in decoding antizyme mRNAs from yeast
Ribosomal frameshifting in decoding antizyme mRNAs from yeast

... antizyme, antizyme 2 (60,69,70). Like antizyme 1, it is widely distributed in different tissues, but is expressed at lower levels. However, it is under tighter evolutionary pressure than antizyme 1, at least in mammals, as evidenced by the 99.5% amino acid identity between the human and mouse antizym ...
CRS questions
CRS questions

... A. Young mice which are +/qk produce more mRNAs which contain exon 12 than do young mice which are qk/qk. Genotype does not appear to influence the pattern of splicing in adult mice. B. Adult mice which are qk/qk produce more mRNAs which contain exon 12 than do adult mice which are +/qk. Genotype do ...
Determination of primary structure
Determination of primary structure

... We just went through the CHEMICAL and PHYSICAL. The BIOINFORMATICAL method requires information from chemical or physical, but only a limited amount of sequence. Example: a sequence of 6 AA is only possible as one of 206 possible hexa-peptide sequences (1 of 64 x 106). There are no more than 50,000 ...
DNA methylation controls histone H3 lysine 9 methylation
DNA methylation controls histone H3 lysine 9 methylation

... histone modi®cations and chromatin structure have mainly been studied at the molecular level for speci®c DNA sequences. Integrated genetic, molecular and cytological approaches can provide new insights into chromatin remodeling. For example, genome-wide H4 acetylation appeared to be tightly linked t ...
5 The Genetics of Bacteria and Their Viruses
5 The Genetics of Bacteria and Their Viruses

... during which the transfer occurred. Therefore, a population containing several different Hfr strains will appear to have an almost random transfer of host genes. This is similar to generalized transduction, in which the viral protein coat forms around a specific amount of DNA rather than specific ge ...
ARE THERE VOICES IN THE GENE:SCHIZOPHRENIA
ARE THERE VOICES IN THE GENE:SCHIZOPHRENIA

... predict inheritance. Scientists trace phenotypes to certain chromosomes and then more specifically to genes on that chromosome. 2. Beginning-level students can complete the first part of the activity; while more advanced students will be challenged by the additional questions. Warn students that eve ...
New Perspectives on Rickettsial Evolution from New
New Perspectives on Rickettsial Evolution from New

... among these species or to other bacteria. This contrasts with the strong chromosome synteny and high gene homology of most well-identified functional proteins as described below; consequently, the reliability of ORF identification appears to decrease with increased genome size and many of these pred ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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