the Liver - Saudi Medical Journal
... associated with embryo loss (8). Anti inflammatory cytokines such as IL10 appear to protect against inflammation-induced miscarriage (9). Research efforts have focused on single nucleotide polymorphisms (SNP) in cytokine genes (1,5), and various SNPs have been reported to be associated with infectio ...
... associated with embryo loss (8). Anti inflammatory cytokines such as IL10 appear to protect against inflammation-induced miscarriage (9). Research efforts have focused on single nucleotide polymorphisms (SNP) in cytokine genes (1,5), and various SNPs have been reported to be associated with infectio ...
Harnessing gene expression to identify the genetic basis of drug
... credited. Creation of derivative works is permitted but the resulting work may be distributed only under the same or similar licence to this one. This licence does not permit commercial exploitation without specific permission. ...
... credited. Creation of derivative works is permitted but the resulting work may be distributed only under the same or similar licence to this one. This licence does not permit commercial exploitation without specific permission. ...
GO2PUB - GenOuest
... GO2PUB options proposes to build some derivated queries based on yours. Your main query will yield results the most close to those waited. However, it could be interesting to see if minor changes can bring you additionnal pertinent results. Indeed, 3 additionnal queries may be added. First, ignoring ...
... GO2PUB options proposes to build some derivated queries based on yours. Your main query will yield results the most close to those waited. However, it could be interesting to see if minor changes can bring you additionnal pertinent results. Indeed, 3 additionnal queries may be added. First, ignoring ...
Association between IGF1R / i16 / TaqI and IGF1 / SnaBI
... understandable. Comparing the sequences of primers designed by Moody et al. [1996] with NCBI reference sequence AC_000178.1 revealed that primers flanking the 625 bp fragment of bovine IGF1R gene are located in the exon 12 (forward primer) and 13 (reverse primer) and that polymorphism mentioned is l ...
... understandable. Comparing the sequences of primers designed by Moody et al. [1996] with NCBI reference sequence AC_000178.1 revealed that primers flanking the 625 bp fragment of bovine IGF1R gene are located in the exon 12 (forward primer) and 13 (reverse primer) and that polymorphism mentioned is l ...
Risks from GMOs due to Horizontal Gene Transfer
... et al., 2004), whereas the simplified conditions in laboratory studies probably lack many of the appropriate biotic and abiotic signals that facilitate HGT in nature (Mel and Mekalanos, 1996; Nielsen and van Elsas, 2001). For example, the presence of algae stimulates the release of bacterial plasmid ...
... et al., 2004), whereas the simplified conditions in laboratory studies probably lack many of the appropriate biotic and abiotic signals that facilitate HGT in nature (Mel and Mekalanos, 1996; Nielsen and van Elsas, 2001). For example, the presence of algae stimulates the release of bacterial plasmid ...
Genomic gains and losses influence expression levels of genes
... as compared to all other subtypes, were equally distributed over the genome in AML subgroups with trisomies. In contrast, 30 and 86% of the most differentially expressed genes characteristic for AML with 5q deletion and monosomy 7 are located on chromosomes 5 or 7. In conclusion, gain of whole chrom ...
... as compared to all other subtypes, were equally distributed over the genome in AML subgroups with trisomies. In contrast, 30 and 86% of the most differentially expressed genes characteristic for AML with 5q deletion and monosomy 7 are located on chromosomes 5 or 7. In conclusion, gain of whole chrom ...
Supplementary Figure Legends (doc 52K)
... Supplementary Figure S2. Distribution of the ‘heavy’ and ‘light’ DNA in separated SIP fractions. The top of each panel shows the DGGE profiles of bacterial PCR products from separated (a) [13C]-phenanthrene fractions aligned to equivalent [12C]-phenanthrene fractions, (b) [13C]naphthalene fractions ...
... Supplementary Figure S2. Distribution of the ‘heavy’ and ‘light’ DNA in separated SIP fractions. The top of each panel shows the DGGE profiles of bacterial PCR products from separated (a) [13C]-phenanthrene fractions aligned to equivalent [12C]-phenanthrene fractions, (b) [13C]naphthalene fractions ...
Tools for Comparing Bacterial Genomes
... around 1.2 Mbp, which is strongly curved and easily melted, and is slightly more AT rich than the rest of the genome. Here, the important carbon-monoxide dehydrogenase gene locus is present, as are multiple transposases, which could be an indication of horizontally acquired DNA. The genome is relati ...
... around 1.2 Mbp, which is strongly curved and easily melted, and is slightly more AT rich than the rest of the genome. Here, the important carbon-monoxide dehydrogenase gene locus is present, as are multiple transposases, which could be an indication of horizontally acquired DNA. The genome is relati ...
Genetics of ankylosing spondylitis
... rural west-Africans (15). Gene-mapping studies in AS The gene-mapping methods available to researchers to identify genes in any disease can be divided into linkage disequilibrium (‘association’) approaches and linkage studies, and in turn these can either be candidate gene or whole genome studies [r ...
... rural west-Africans (15). Gene-mapping studies in AS The gene-mapping methods available to researchers to identify genes in any disease can be divided into linkage disequilibrium (‘association’) approaches and linkage studies, and in turn these can either be candidate gene or whole genome studies [r ...
Possible consequences of the overlap between the CaMV 35S
... (Caulimoviridae) that infects members of the Brassicaceae family. CaMV was one of first plant DNA viruses to be studied, and its double-stranded circular DNA genome [~8 kg base (kb)] has been completely sequenced.1 The genome encodes seven genes and has a large (~700 bp) and a small (~150 bp) interg ...
... (Caulimoviridae) that infects members of the Brassicaceae family. CaMV was one of first plant DNA viruses to be studied, and its double-stranded circular DNA genome [~8 kg base (kb)] has been completely sequenced.1 The genome encodes seven genes and has a large (~700 bp) and a small (~150 bp) interg ...
PHS 416-1/416-9Continuation (Rev. 10/05), Continuation Format
... RD in several families, although a replication of this result has not yet been attempted. Overall, the identification of several linkage peaks and candidate genes for RD is consistent with a multifactorial etiology for the disorder, which likely involves several genes that increase susceptibility to ...
... RD in several families, although a replication of this result has not yet been attempted. Overall, the identification of several linkage peaks and candidate genes for RD is consistent with a multifactorial etiology for the disorder, which likely involves several genes that increase susceptibility to ...
060506-Meeting
... • Conjugative plasmids are very large, from 60k – 100k basepairs long •The TraJ protein is a regulatory protein responsible for initiating the DNA transfer cascade •DNA transfer during conjugation always begins at a specific sequence on the plasmid, OriT, the Origin of Transfer. ...
... • Conjugative plasmids are very large, from 60k – 100k basepairs long •The TraJ protein is a regulatory protein responsible for initiating the DNA transfer cascade •DNA transfer during conjugation always begins at a specific sequence on the plasmid, OriT, the Origin of Transfer. ...
draft - University of Michigan
... measures of gene expression (Marbach et al. 2012). Using the edges in this network, we compared the proportion of X-linked target genes for X-linked and autosomal TFs (Figure 5A). For the 213 TFs included in our set of 4851 genes, 46 of which are X-linked (21.6%), we found that TFs encoded by genes ...
... measures of gene expression (Marbach et al. 2012). Using the edges in this network, we compared the proportion of X-linked target genes for X-linked and autosomal TFs (Figure 5A). For the 213 TFs included in our set of 4851 genes, 46 of which are X-linked (21.6%), we found that TFs encoded by genes ...
Coding Regions of MSX1 do not Contribute to Non
... with NS-CL/P and in this family, intronic CA repeats may be the causing factor for the onset of the anomaly [21]. It is hard to identify the candidate gene functions in multi-factorial inheritance patterns. As a result of this status, a large and different population analysis including case- control ...
... with NS-CL/P and in this family, intronic CA repeats may be the causing factor for the onset of the anomaly [21]. It is hard to identify the candidate gene functions in multi-factorial inheritance patterns. As a result of this status, a large and different population analysis including case- control ...
Gene Section SIL (SCL/TAL1 interrupting locus) Atlas of Genetics and Cytogenetics
... (NSCLC). In addition, high expression levels in lung adenocarcinoma, lung squamous carcinoma and lung small cell carcinoma. ...
... (NSCLC). In addition, high expression levels in lung adenocarcinoma, lung squamous carcinoma and lung small cell carcinoma. ...
Deciphering the developmental program in the ascidian
... Four mechanisms that can establish spatial patterns of gene expression Spatial patterns of gene expression might be established in a number of different ways during early development. It is possible to envisage that the expression patterns of some genes are determined via a two-step (rough and fine) ...
... Four mechanisms that can establish spatial patterns of gene expression Spatial patterns of gene expression might be established in a number of different ways during early development. It is possible to envisage that the expression patterns of some genes are determined via a two-step (rough and fine) ...
Coexpression of Linked Genes in Mammalian
... coexpressed genes in several yeasts supports the adaptive model (Hurst et al. 2002), considering the recent discovery of long-range coregulation (;100 kb, covering ;30 genes) of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be hi ...
... coexpressed genes in several yeasts supports the adaptive model (Hurst et al. 2002), considering the recent discovery of long-range coregulation (;100 kb, covering ;30 genes) of linked yeast genes (Lercher and Hurst 2006), the adaptive model implies that the gene order in the yeast genome must be hi ...
Why do we care about genetic variations?
... Affect gene transcription quantitatively or qualitatively. Affect gene translation quantitatively or qualitatively. Change protein structure and functions. Change gene regulation at different steps. ...
... Affect gene transcription quantitatively or qualitatively. Affect gene translation quantitatively or qualitatively. Change protein structure and functions. Change gene regulation at different steps. ...
Dominant and Recessive Genes
... Through this discussion you should lead students to the Red Angus breed. For the purpose of this lesson B is the dominant gene in cattle that codes for a black coat; b is the recessive form of this allele that codes for a red coat. Using just this information can you think of a breeding program wher ...
... Through this discussion you should lead students to the Red Angus breed. For the purpose of this lesson B is the dominant gene in cattle that codes for a black coat; b is the recessive form of this allele that codes for a red coat. Using just this information can you think of a breeding program wher ...
Differential Gene Expression in the Siphonophore
... data to quantify expression. Some of these studies lack biological replication, which makes it difficult to assess the significance of the results. The wide variation in methods across these studies provide interesting glimpses into the benefits and drawbacks of different approaches for measuring ex ...
... data to quantify expression. Some of these studies lack biological replication, which makes it difficult to assess the significance of the results. The wide variation in methods across these studies provide interesting glimpses into the benefits and drawbacks of different approaches for measuring ex ...
The Euglena gracilis chloroplast rpoB gene
... We are interested in the relationship between chloroplast genes for RNA polymerase subunits and the known chloroplast polymerase activities. Antibodies against fusion proteins that contained fragments of the chloroplast genes rpoA from spinach, rpoB from tobacco, and rpoC2 from Euglena, were able to ...
... We are interested in the relationship between chloroplast genes for RNA polymerase subunits and the known chloroplast polymerase activities. Antibodies against fusion proteins that contained fragments of the chloroplast genes rpoA from spinach, rpoB from tobacco, and rpoC2 from Euglena, were able to ...
Single nucleotide polymorphism in coronary
... complications, including drawback due to ISR. 1 Single nucleotide polymorphism (SNP) is a genetic variation leading to change in one specific location causing significant change in coded protein. It leads to over 90% of genetic variation in human species and may vary among different population group ...
... complications, including drawback due to ISR. 1 Single nucleotide polymorphism (SNP) is a genetic variation leading to change in one specific location causing significant change in coded protein. It leads to over 90% of genetic variation in human species and may vary among different population group ...
Supplementary Text - Austin Publishing Group
... Thus, there are 229 genes (excluding HTT) co-expressed with wild type HTT. For example, Adducin 1 (alpha) gene (ADD1) was co-expressed with HTT having MR= 86.1 and 8.1 in two independent human samples. Similarly, exportin 6 (XPO6) and mediator complex subunit 15 (MED15) genes were co-expressed with ...
... Thus, there are 229 genes (excluding HTT) co-expressed with wild type HTT. For example, Adducin 1 (alpha) gene (ADD1) was co-expressed with HTT having MR= 86.1 and 8.1 in two independent human samples. Similarly, exportin 6 (XPO6) and mediator complex subunit 15 (MED15) genes were co-expressed with ...
Correlated selection responses in animal domestication: chickens
... the involved characteristics were influenced by common a genetic mechanism. Such a common mechanism could be for example pleiotropy, which is the case when one gene affects several traits (e.g. by the gene product being involved in more than one biochemical pathway). The correlation between traits c ...
... the involved characteristics were influenced by common a genetic mechanism. Such a common mechanism could be for example pleiotropy, which is the case when one gene affects several traits (e.g. by the gene product being involved in more than one biochemical pathway). The correlation between traits c ...
genomic flux: genome evolution by gene loss and
... this way, one may sort bacterial genes into broad classes that reflect their average importance to the cell (Table 1). Mutations in genes making essential or very important contributions to the cell will be strongly counterselected in bacterial populations, since these mutants cannot compete effecti ...
... this way, one may sort bacterial genes into broad classes that reflect their average importance to the cell (Table 1). Mutations in genes making essential or very important contributions to the cell will be strongly counterselected in bacterial populations, since these mutants cannot compete effecti ...