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Slide 1
Slide 1

... biological functions. Non-coding regions typically lack such annotation. GREAT assigns biological meaning to a set of non-coding genomic regions by analyzing the annotations of the nearby genes. Thus, it is particularly useful in studying functions of sets of non-coding genomic regions. ...
Gene–Nutrition Interaction in Human Performance and Exercise
Gene–Nutrition Interaction in Human Performance and Exercise

... to some extent may be rooted in our genes. Heritability (the amount of variation in a trait that can be accounted for by variation in genes) estimates for physical activity measured by self-report or by observation range from 0.29 to 0.62, with the wide span in estimates likely due to differences in ...
Analysis of Biological Networks: Genetic Interaction Networks
Analysis of Biological Networks: Genetic Interaction Networks

... arrows synthetic sick interactions of bud6 are marked. Synthetic sick interaction exhibit slow growth and small culture size. after first screen. Assuming that gene pairs not yet tested by the SGA analysis, behave similarly to those analyzed in [4], the yeast synthetic genetic network contains an or ...
A familial inverted duplication/deletion of 2p25.1–25.3
A familial inverted duplication/deletion of 2p25.1–25.3

WGCNA: an R package for weighted correlation network analysis
WGCNA: an R package for weighted correlation network analysis

... for calculating module membership measures. Correlation networks facilitate network based gene screening methods that can be used to identify candidate biomarkers or therapeutic targets. These methods have been successfully applied in various biological contexts, e.g. cancer, mouse genetics, yeast g ...
Detailed Algorithm of the DBRF
Detailed Algorithm of the DBRF

... For each pair of gene i and gene j in the expression profiles, the existence of gene regulation between those genes is determined as described in Kyoda et al. (2000). A positive (negative) edge directing from gene i to gene j, denoted by eij, is deduced when the expression level of gene j in the del ...
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights
—1— User Guide © Copyright 2009 Robert C. Edgar, all rights

... The core components simulate inter- and intra-chromosome evolution, respectively. The inter-chromosome module (inter) simulates events involving two chromosomes, including chromosome fission, fusion and segmental moves and copies in which the target chromosome is different from the source chromosome ...
pathways_tutorial
pathways_tutorial

... •Data is under development and subject to change. If you do see any errors in the dataset please feel free to contact us through the feedback provided at the top of Gramene webpages. ...
A strategy for extracting and analyzing large
A strategy for extracting and analyzing large

... were removed from the data, as these scores would tend to be negative whether or not a synthetic genetic interaction exists between the two genes (Figure 1c). Additionally, large standard deviation measurements were used to identify unusually noisy test and query strains, which likely resulted from ...
Crossing Over…Markov Meets Mendel
Crossing Over…Markov Meets Mendel

aabb
aabb

... 3. The dominant factor prevents the recessive factor from being expressed. 4. Recessive factors are only expressed when both factors in the pair are recessive. 5. When pea plants reproduce, a factor pair is segregated (split) and each factor ends up in a separate gamete. Mendel’s law of segregation. ...
The Genetics of Microcephaly
The Genetics of Microcephaly

... why males are more liable to be affected by certain diseases or traits such as colour blindness that are caused by faults within genes located on their solitary X chromosome. Different Types of Genetic Microcephaly Aside from microcephaly caused by major chromosome abnormalities such as Down's syndr ...
Playing by pair-rules?
Playing by pair-rules?

... insects),(reviewed in Ref. 4) crustaceans,(5–8) myriapods (millipedes and centipedes)(9) and chelicerates (spiders, mites, scorpions and horseshoe crabs)(10–12) (Fig. 1). In all cases, wg stripes lie adjacent and anterior to stripes of en and these observations, together with functional studies in t ...
Selection of Suitable Endogenous Reference Genes for Relative
Selection of Suitable Endogenous Reference Genes for Relative

... numbers when relevant restriction sites are lacking [13]. These techniques are even harder in the sugarcane hybrid due to the complicated genome of 10 to 12 Gb [14] and 3.05–8.91 pg/2C [15]. In addition, sugarcane transgenic breeding needs a transformation population for selection of plants with the ...
The sequence of a gene encoding convicilin from pea
The sequence of a gene encoding convicilin from pea

... sequence in soya-bean (Glycine max) conglycinin (a homologous vicilin-type protein) suggests that the two insertions were independent events. The 5' flanking sequence of the gene contains several putative regulatory elements, besides a consensus promoter sequence. INTRODUCTION Convicilin has been te ...
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)
IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS)

... which can be differentiate from other Aeromonas sp. as it can produce gas from glucose but does not hydrolyze esculin [12], whereas, other Aeromonas sp. produce gas from glucose and hydrolyze esculin. Similar identification protocols for identification of Aeromonas sp. were also followed by other re ...
A Rapid Chromosome Mapping Method for Cloned Fragments of Yeast DNA.
A Rapid Chromosome Mapping Method for Cloned Fragments of Yeast DNA.

... behind the 2p mapping method is similar in some ways to other mitotic mapping methods: loss of information from particular chromosomes is detected by the appearance of recessive phenotypes in heterozygous diploids. However, the method differs from other mitotic methods in the way in which chromosome ...
Threading-based Protein Structure Prediction
Threading-based Protein Structure Prediction

... as many known coding regions as possible, and at the same time excludes as many known non-coding regions as possible Copyright © 2004, 2005 by Limsoon Wong ...
Genome-Wide Analysis of Core Cell Cycle Genes in
Genome-Wide Analysis of Core Cell Cycle Genes in

... Thr kinases, known as cyclin-dependent kinases (CDKs). CDK activity is regulated in a complex manner, including phosphorylation/dephosphorylation by specific kinases/phosphatases and association with regulatory proteins. Although many cell cycle genes of plants have been identified in the last decad ...
Comparative Metagenomic Analysis Reveals Mechanisms for Stress
Comparative Metagenomic Analysis Reveals Mechanisms for Stress

... Understanding microbial adaptation to environmental stressors is crucial for interpreting broader ecological patterns. In the most extreme hot and cold deserts, cryptic niche communities are thought to play key roles in ecosystem processes and represent excellent model systems for investigating micr ...
Models of Selection, Isolation, and Gene Flow in Speciation
Models of Selection, Isolation, and Gene Flow in Speciation

... Among several coalescent population-genetic methods that have been developed to model the evolution of genetic diversity and disparity associated with new species formation, two are especially informative and broadly useful. Both methods use gene trees of diverging lineages to extract useful insight ...
Journal of Biotechnology
Journal of Biotechnology

... The circular chromosome consists of 3,918,589 bps with predicted 3695 protein-coding sequences (Chen et al., 2007). Software package Mauve (Darling et al., 2004) was used to compare the genomes of B. amyloliquefaciens FZB42, B. subtilis 168, B. licheniformis and B. pumilus. The four species belong t ...
Identifying Signatures of Natural Selection in Tibetan Data
Identifying Signatures of Natural Selection in Tibetan Data

... unique suite of physiological changes to the decreased oxygen available at altitude. However, we are just beginning to understand the genetic changes responsible for the observed physiology. The aim of the current study was to identify gene regions that may be involved in adaptation to high altitude ...
network - bioinf leipzig
network - bioinf leipzig

... The model based on experimental evidence in yeast organizes TFs in a stratified nature of three distinct layers: the top, core, and bottom layers. TFs within a layer are highly interconnected and share similar properties. TFs of the different layers regulate distinct sets of targets genes. The three ...
The role of regulatory variation in complex traits and
The role of regulatory variation in complex traits and

... Distant eQTLs. Distant eQTLs are defined as loci that are located further away from the genes they influence. The precise distance required for an eQTL to be distant is arbitrary and can be defined in physical or genetic distance; consequently, it differs between studies. For example, such a distanc ...
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Gene desert

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