Reciprocal products of chromosomal translocations in human
... frequently reported in non-Hodgkin’s lymphoma. BCL-6 is normally expressed in B and CD4+ T cells in germinal centers (GC), and plays an essential role in GC formation [7]. BCL-6 expression is deregulated in non-Hodgkin lymphomas arising from GC B cells, as a result of two distinct mechanisms: (1) ch ...
... frequently reported in non-Hodgkin’s lymphoma. BCL-6 is normally expressed in B and CD4+ T cells in germinal centers (GC), and plays an essential role in GC formation [7]. BCL-6 expression is deregulated in non-Hodgkin lymphomas arising from GC B cells, as a result of two distinct mechanisms: (1) ch ...
one
... One of Mendel’s conclusions from his work on inheritance in pea plants was the law of independent assortment, which stated that genes assort independently of each other during meiosis. However, later experiments suggested that some genes were linked together and did not assort independently. Eventua ...
... One of Mendel’s conclusions from his work on inheritance in pea plants was the law of independent assortment, which stated that genes assort independently of each other during meiosis. However, later experiments suggested that some genes were linked together and did not assort independently. Eventua ...
Molecular ecology and selection in the drought-
... previously surveyed in these populations. This suggests that strong purifying selection has been acting on this gene. In contrast, Asr2 exhibited higher levels of nucleotide diversity, which is indicative of adaptive selection. These patterns were more notable in wild beans than in cultivated common ...
... previously surveyed in these populations. This suggests that strong purifying selection has been acting on this gene. In contrast, Asr2 exhibited higher levels of nucleotide diversity, which is indicative of adaptive selection. These patterns were more notable in wild beans than in cultivated common ...
Article The Pseudoautosomal Regions of the U/V Sex
... size (Spearman’s correlation test = 0.113, P = 0.598) whereas gene density and GC percentage increase with ...
... size (Spearman’s correlation test = 0.113, P = 0.598) whereas gene density and GC percentage increase with ...
View Poster - Technology Networks
... We found 68 candidate miRNA precursors Four miRNA candidates out of 8 tested by northern blot showed differential expression in gametes and vegetative cells Potential targets for four out of 18 tested candidate miRNAs could be verified by 5’ RACE analysis, showing cleavage in the centre of the predi ...
... We found 68 candidate miRNA precursors Four miRNA candidates out of 8 tested by northern blot showed differential expression in gametes and vegetative cells Potential targets for four out of 18 tested candidate miRNAs could be verified by 5’ RACE analysis, showing cleavage in the centre of the predi ...
Poster: Litter size in Norwegian White Sheep
... Data for the ram circle members with Norwegian White Sheep (NWS) was retrieved from the Norwegian Sheep Recording System. Lambing data from ewes older than six years was discarded. The mean litter size in 2015 was 2.33. One year old ewes had the lowest mean (1.88), increasing the second year (to 2.2 ...
... Data for the ram circle members with Norwegian White Sheep (NWS) was retrieved from the Norwegian Sheep Recording System. Lambing data from ewes older than six years was discarded. The mean litter size in 2015 was 2.33. One year old ewes had the lowest mean (1.88), increasing the second year (to 2.2 ...
Chapter 1 - Bioinformatics Research Center
... sequence tags, simple repeats, or restriction enzyme polymorphisms), but may include phenotypes associated with Mendelian loci. In diploid organisms, genetic maps are typically assembled from data on the co-segregation of genetic markers either in pedigrees or in the progeny of controlled crosses. T ...
... sequence tags, simple repeats, or restriction enzyme polymorphisms), but may include phenotypes associated with Mendelian loci. In diploid organisms, genetic maps are typically assembled from data on the co-segregation of genetic markers either in pedigrees or in the progeny of controlled crosses. T ...
Genetics Unit-- Make a Face Lab
... Red Hair: Red hair is another gene for hair color present on a different chromosome.It blends its effect with other hair colors. Redness of the hair seems to be caused by a single gene pair with two alleles, red (G) or no red (g), and displays incomplete dominance. Thus, if a person has two genes f ...
... Red Hair: Red hair is another gene for hair color present on a different chromosome.It blends its effect with other hair colors. Redness of the hair seems to be caused by a single gene pair with two alleles, red (G) or no red (g), and displays incomplete dominance. Thus, if a person has two genes f ...
You`re one in a googol: optimizing genes for protein expression
... Several different prokaryotic and eukaryotic systems are now available for heterologous expression, offering flexibility for a variety of protein types and applications. For improved results, these systems can be further manipulated by changing environmental conditions such as temperature or media co ...
... Several different prokaryotic and eukaryotic systems are now available for heterologous expression, offering flexibility for a variety of protein types and applications. For improved results, these systems can be further manipulated by changing environmental conditions such as temperature or media co ...
Letter Gene Survival and Death on the Human Y
... whether, among X-linked genes, those with functional Y homologs show different expression patterns than those without functional Y homologs. Using RNAseq expression data (Brawand et al. 2011), we observed that X-linked genes with functional Y homologs are expressed at higher levels (at least 2-fold ...
... whether, among X-linked genes, those with functional Y homologs show different expression patterns than those without functional Y homologs. Using RNAseq expression data (Brawand et al. 2011), we observed that X-linked genes with functional Y homologs are expressed at higher levels (at least 2-fold ...
Leukaemia Section 11q23 rearrangements in leukaemia Atlas of Genetics and Cytogenetics
... - t(X;11)(q13;q23): rare; ANLL; the gene involved in Xq13 is AFX1, a transcription regulator. - t(1;11)(p32;q23): rare; ALL and ANLL; the gene involved in 1p32 is AF1P. - t(1;11)(q21;q23): rare; mostly M4 ANLL; the gene involved in 1q21 is AF1q. - t(2;11)(p21;q23): rare; ANLL and MDS; may be found a ...
... - t(X;11)(q13;q23): rare; ANLL; the gene involved in Xq13 is AFX1, a transcription regulator. - t(1;11)(p32;q23): rare; ALL and ANLL; the gene involved in 1p32 is AF1P. - t(1;11)(q21;q23): rare; mostly M4 ANLL; the gene involved in 1q21 is AF1q. - t(2;11)(p21;q23): rare; ANLL and MDS; may be found a ...
GIN Transposons: Genetic Elements Linking Retrotransposons and
... retrotransposons of the Mdg1 clade (Lloréns and Marı́n 2001). Therefore, all the animal sequences that were potentially interesting were selected and phylogenetic trees were built including them and also sequences from Mdg1 retrotransposons, which were to be used as outgroups. The results are shown ...
... retrotransposons of the Mdg1 clade (Lloréns and Marı́n 2001). Therefore, all the animal sequences that were potentially interesting were selected and phylogenetic trees were built including them and also sequences from Mdg1 retrotransposons, which were to be used as outgroups. The results are shown ...
Article Why There Are No Essential Genes on
... chromosomal genes (Werren 2011). At the very least, the different evolutionary trajectories and interests of plasmids and chromosomes mean that the average genetic composition of each is likely to differ. ...
... chromosomal genes (Werren 2011). At the very least, the different evolutionary trajectories and interests of plasmids and chromosomes mean that the average genetic composition of each is likely to differ. ...
FEBS Letters
... from the A. variabilis D N A composition, as shown in the table below. In addition to hoxH, the 5.0 kb segment contained upstream of hoxH the hydrogenase genes h o x Y (coding for the smaller subunit o f the hydrogenase dimer, sequence identity to the A. variabilis gene product 61% on an amino acid ...
... from the A. variabilis D N A composition, as shown in the table below. In addition to hoxH, the 5.0 kb segment contained upstream of hoxH the hydrogenase genes h o x Y (coding for the smaller subunit o f the hydrogenase dimer, sequence identity to the A. variabilis gene product 61% on an amino acid ...
Causes, consequences and solutions of
... Phylogenetic analysis is used to recover the evolutionary history of species, genes or proteins. Understanding phylogenetic relationships between organisms is a prerequisite of almost any evolutionary study, as contemporary species all share a common history through their ancestry. Moreover, it is i ...
... Phylogenetic analysis is used to recover the evolutionary history of species, genes or proteins. Understanding phylogenetic relationships between organisms is a prerequisite of almost any evolutionary study, as contemporary species all share a common history through their ancestry. Moreover, it is i ...
Lampetra fluviatilis Neurotrophin Homolog, Descendant of a
... gene family that dates back more than 460 million years to the early vertebrate ancestors. The results show that the neurotrophin gene family was originally formed by two subsequent duplications. The duplication that formed nerve growth factor, neurotrophin-3, brain-derived neurotrophic factor, and ...
... gene family that dates back more than 460 million years to the early vertebrate ancestors. The results show that the neurotrophin gene family was originally formed by two subsequent duplications. The duplication that formed nerve growth factor, neurotrophin-3, brain-derived neurotrophic factor, and ...
Strong dominance of functional alleles over gene deletions in
... 2010). The heterozygous fitness effects of the engineered deletions were soon found to be very similar regardless of whether the homozygous deletions were lethal or mild (Steinmetz et al., 2002). This was true for all major categories of genes that were analysed, not just for genes encoding enzymes ...
... 2010). The heterozygous fitness effects of the engineered deletions were soon found to be very similar regardless of whether the homozygous deletions were lethal or mild (Steinmetz et al., 2002). This was true for all major categories of genes that were analysed, not just for genes encoding enzymes ...
chapter 15
... Sturtevant used the testcross design to map the relative position of three fruit fly genes, body color (b), wing size (vg), and eye color (cn). The recombination frequency between cn and b is 9%. The recombination frequency between cn and vg is 9.5%. The recombination frequency between b and ...
... Sturtevant used the testcross design to map the relative position of three fruit fly genes, body color (b), wing size (vg), and eye color (cn). The recombination frequency between cn and b is 9%. The recombination frequency between cn and vg is 9.5%. The recombination frequency between b and ...
Prediction and Validation of Gene-Disease Associations
... of heterogeneous data sets and uses support vector machines (SVMs) to identify potential gene-disease associations. In the past decades, the growth of gene-phenotype associations in model species has been explosive, which suggests an alternative way to find candidate genes for human diseases. McGary ...
... of heterogeneous data sets and uses support vector machines (SVMs) to identify potential gene-disease associations. In the past decades, the growth of gene-phenotype associations in model species has been explosive, which suggests an alternative way to find candidate genes for human diseases. McGary ...
DNA Chips: Genes to Disease
... could use microarray analysis. As the first step in this process, a gene chip would be created. DNA chip, microarray, gene chip, and genome chip are all terms that describe a solid matrix, such as a glass slide, that is imprinted with a precisely arranged pattern of spots, each made up of many copie ...
... could use microarray analysis. As the first step in this process, a gene chip would be created. DNA chip, microarray, gene chip, and genome chip are all terms that describe a solid matrix, such as a glass slide, that is imprinted with a precisely arranged pattern of spots, each made up of many copie ...
Powerpoint
... If you allow access to a single or a group of your chips () to a colleague, the colleague would be able to perform comparisons with any of his own chips. ...
... If you allow access to a single or a group of your chips () to a colleague, the colleague would be able to perform comparisons with any of his own chips. ...
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... During the past several years, searching susceptibility loci for various human diseases has been revolutionized by genome-wide association studies (GWAS). Although a significant number of single-nucleotide polymorphism (SNP) have been reported to be associated with various human complex traits [1], ...
... During the past several years, searching susceptibility loci for various human diseases has been revolutionized by genome-wide association studies (GWAS). Although a significant number of single-nucleotide polymorphism (SNP) have been reported to be associated with various human complex traits [1], ...
Functional tests of enhancer conservation between
... can rescue an unc-30 mutant in C. elegans (Westmoreland et al., 2001). unc-30 controls the differentiation of GABAergic neurons in nematodes, activating the expression of several target genes, including unc-25 (glutamic acid decarboxylase) and unc-47 (GABA transporter) genes (Eastman et al., 1999), ...
... can rescue an unc-30 mutant in C. elegans (Westmoreland et al., 2001). unc-30 controls the differentiation of GABAergic neurons in nematodes, activating the expression of several target genes, including unc-25 (glutamic acid decarboxylase) and unc-47 (GABA transporter) genes (Eastman et al., 1999), ...
Lecture 16 Notes CH.15
... • 15.3 Linked genes tend to be inherited together because they are located near each other on the same chromosome • 15.4 Alterations of chromosome number or structure cause some genetic disorders • 15.5 Some normal inheritance patterns are exceptions to the standard Mendelian inheritance ...
... • 15.3 Linked genes tend to be inherited together because they are located near each other on the same chromosome • 15.4 Alterations of chromosome number or structure cause some genetic disorders • 15.5 Some normal inheritance patterns are exceptions to the standard Mendelian inheritance ...