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Smchd1 regulates a subset of autosomal genes subject to
Smchd1 regulates a subset of autosomal genes subject to

... total) were distributed between those with increased transcript levels (157 genes) and those with decreased levels (133 genes) in Smchd1MommeD1/MommeD1 compared with Smchd1+/+ embryos. The cell cycle related genes Ccng1 and Cdkn1a were high in the ranked list of significantly upregulated transcripts ...
An Upstream Enhancer Region Located at -1810/
An Upstream Enhancer Region Located at -1810/

... significant increase in luciferase values for both lines with increased ovulation rates, Meishan and Index, over that of Control. Reduction of the proximal promoter from 5118 to 1900 bp relative to the translational start site maintained a 2-4 fold increase in luciferase activity (Index and Meishan, ...
Protocol S1.
Protocol S1.

... the variables (s, x), since these correspond to the observed data that can be gathered easily (recall that x is the frequency of sinistrals amongst offspring of sinistral snails; Eq. 1). When there is complete assortment ( = 1), two equilibria become possible (A, B in Eq. 5). In the first (A), the ...
Figure 5 - GEP Community Server
Figure 5 - GEP Community Server

... looking at the genome. You saw an example of this previously in Module 1. Sometimes we can infer the correct reading frame given the pattern of start and stop codons within the region of the exon, identified by RNA-Seq data. But that sort of information does not always give a definitive answer – the ...
module 5: translation - GEP Community Server
module 5: translation - GEP Community Server

... looking at the genome. You saw an example of this previously in Module 1. Sometimes we can infer the correct reading frame given the pattern of start and stop codons within the region of the exon, identified by RNA-Seq data. But that sort of information does not always give a definitive answer – the ...
UvA-DARE (Digital Academic Repository)
UvA-DARE (Digital Academic Repository)

... presymptomatic family members at risk for fatal events. We uncovered several genealogically linked families affected by numerous sudden cardiac deaths over the past centuries, attributed to familial idiopathic ventricular fibrillation. Notably, ventricular fibrillation in these families was provoked ...
20060710_GOannotCamp_Stanford
20060710_GOannotCamp_Stanford

... o How are terms used related to each other? Parent/child? o Are the terms an exact match? o Are the terms on the same or different branch? o If different, how far apart are these branches? o Note: Changes in the GO tree are not taken into account as the study was done over a relatively short amount ...
Module 5: Alternative Open Reading Frame
Module 5: Alternative Open Reading Frame

... over the first nucleotide of the highlighted in the start codon and a popup box will show up that has the nucleotide number indicated. Make a note of the number. Scroll down the page until you come to the highlighted stop codon in the same reading frame. Hover your cursor over the LAST nucleotide in ...
Ch. 7: Presentation Slides
Ch. 7: Presentation Slides

... to mispairing and unequal crossing-over • Unequal crossing-over between these genes during meiotic recombination can also result in gene deletion and colorblindness • Results in chimeric (composite) gene ...
Retrovirus Integration Database (RID): a public database for
Retrovirus Integration Database (RID): a public database for

... select the “Submit Query” button to display the query result. Users can limit their query by choosing an option in the “Query option” section. For example, a nucleotide position range on a specific chromosome can be chosen to search for integration sites within a specific region of the host genome o ...
Genetic Epidemiology of Obesity
Genetic Epidemiology of Obesity

... etiology makes management and prevention of obesity especially challenging. While a genetic basis for obesity exists, defining the genetic contribution has proven to be a formidable task. Genetic epidemiologic methods for the gene discovery of complex traits, such as obesity, can be divided into two ...
Tissue-specific codon usage and the expression of
Tissue-specific codon usage and the expression of

... length within each tissue is well within one standard deviation of the means of all other tissues.) We have compared codon usage between pairs of the six tissues. When comparing testis to uterus, for example, we calculate the distance between the codon usage of every pair of genes (including pairs f ...
A genome-wide association study identifies an osteoarthritis
A genome-wide association study identifies an osteoarthritis

... few good options for treatment of symptoms. OA is a complex disease in which both environmental and genetic factors play an important role. Primary OA has an estimated heritability of 40% for the knee, 60% for the hip, and 65% for the hand (1). Identifying the genes underlying the genetic background ...
Getting Started
Getting Started

... public databases (eg. NCBI, UniProtKB) genome browsers (eg. Ensembl) array vendors (eg. Affymetrix) ...
Fluorescence in Situ Hybridization Evaluation of c-erbB
Fluorescence in Situ Hybridization Evaluation of c-erbB

Mutations in the MicroRNA Complementarity Site
Mutations in the MicroRNA Complementarity Site

... carpels. Our results suggest that the ICU4 gene has an adaxializing function and that it is down-regulated by microRNAs that require the HASTY protein for their biogenesis. ...


... by Cm-PL-3 and Cm-PL-10 was detected 48 h post inoculation, for Cg-14 and L-2.5 only after 120 h (Fig. 4B). Inoculation of watermelon seedlings with Cm-PL-10 and Cm-PL-3 caused damping off and leaf necrosis, whereas no symptoms developed with the two wild-type isolates Cg-14 and L-2.5, 6 days post i ...
The gene responsible for Clouston hidrotic
The gene responsible for Clouston hidrotic

... inductive ectoderm–mesoderm reciprocal interactions (31) and because hearing loss has been reported in a few cases of HED (9), it is possible that these three diseases are caused by different mutations in the same gene or in related genes found in a cluster. The candidate region for the HED gene con ...
PDF - American Society of Mammalogists
PDF - American Society of Mammalogists

... phenotype (Fig. 2A). The gene Igf 2 was the 1st gene reported to be imprinted (DeChiara et al. 1990), because of the unexpected inheritance pattern of the mutant phenotype. Almost simultaneously, a report came that the Igf2 receptor (Igf2r) was expressed only from the maternal allele (Barlow et al. ...
Estrogen receptor β gene polymorphisms and susceptibility to
Estrogen receptor β gene polymorphisms and susceptibility to

... leiomyomas when compared with autologous myometrial tissue [7–11]. In 1996, the second estrogen receptor, ERb, was identified which is coded by the ESR2 gene. Like ERa, ERb also was reported to be expressed at higher levels in leiomyomas when compared with matched myometrium [12]. There are studies ...
Involvement of respiratory chain in biofilm formation in - HAL
Involvement of respiratory chain in biofilm formation in - HAL

... bioilm with P. gingivalis and S. gordonii did not show any difference between mutant strains and wild-type strain: bioilms were completely formed after 3 hours. Analysis of static mono-bacterial bioilm showed that mutant strains induced the formation of a bioilm after 5 hours whereas wild-type strai ...
User`s guide to GO
User`s guide to GO

... Using the GO Decide on GO analysis tool  How much GO is available for your species?  Getting GO for you data set  Adding GO for your data ...
Ap Biology Discussion Notes
Ap Biology Discussion Notes

... - When cone cells with the MWS opsin protein are stimulated AND cone cells with the SWS opsin are stimulated, violet color is perceived by the brain. - When cone cells with the SWS opsin protein are stimulated AND cone cells with the LWS opsin are stimulated, cyan color is perceived by the brain. - ...
Correlation of length of VNTR alleles at the X
Correlation of length of VNTR alleles at the X

... many males had problems with impulsive, aggressive and hypersexual behaviors due to a hemizygous chain termination mutation in the MAOA gene. This was consistent with the numerous other studies suggesting a correlation between low MAO levels and impulsive, risk-taking, externalizing behaviors. Becau ...
Biomart/ GENOME ALIGNMENT III
Biomart/ GENOME ALIGNMENT III

... The comparison of the mouse and human genomes has demonstrated the power of comparative genomics in inferring the evolutionary history of species and in identifying functional regions in genomes. The possibilities for identifying regions under selection are enhanced with the addition of more sequenc ...
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