Solving the University Timetabling Problem with
... general the timetabling problem consists of assigning each lecture from a set of lectures to a suitable room and a time slot subject to a number of hard and soft constraints, such as no teacher can teach more lectures at the same time, at no room can be taught more than one lecture at the same time, ...
... general the timetabling problem consists of assigning each lecture from a set of lectures to a suitable room and a time slot subject to a number of hard and soft constraints, such as no teacher can teach more lectures at the same time, at no room can be taught more than one lecture at the same time, ...
Plumage Genes and Little Else Distinguish the Genomes of
... be required before there can be any association with feather pigmentation or patterning in this or other systems. Correlations of variation at particular feather tracts and specific genetic variants imply even stronger associations between genotype and phenotype. For example, the black throat of gol ...
... be required before there can be any association with feather pigmentation or patterning in this or other systems. Correlations of variation at particular feather tracts and specific genetic variants imply even stronger associations between genotype and phenotype. For example, the black throat of gol ...
Triple-hit lymphoma
... lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymphoma has different prognostic and therapeutic implications than other ...
... lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymphoma has different prognostic and therapeutic implications than other ...
Genes@ Work: an efficient algorithm for pattern discovery and
... demonstrated with a specific example to discover genes in two independently collected sets of lymphoma data. We finish the paper with some concluding remarks. ...
... demonstrated with a specific example to discover genes in two independently collected sets of lymphoma data. We finish the paper with some concluding remarks. ...
Nucleotide Polymorphisms in the 2 Gene Define
... In the present study, we have continued our analysis of the a2 gene to determine if additional sequence polymorphisms exist that are associated with the 807 and 873 polymorphisms and with expression levels of a2b1. Analysis of a larger group of individuals has now led to the identification of an add ...
... In the present study, we have continued our analysis of the a2 gene to determine if additional sequence polymorphisms exist that are associated with the 807 and 873 polymorphisms and with expression levels of a2b1. Analysis of a larger group of individuals has now led to the identification of an add ...
Seed-Specific Gene Activation Mediated by the Cre//ox Site
... altering Cre expression. Efficient Cre expression ultimately directed gene activation throughout the model tissue, whereas inefficient Cre expression resulted in mosaic tissue. limited gene activation provides a system for cell lineage and developmental analyses. ...
... altering Cre expression. Efficient Cre expression ultimately directed gene activation throughout the model tissue, whereas inefficient Cre expression resulted in mosaic tissue. limited gene activation provides a system for cell lineage and developmental analyses. ...
Interactions of Mitochondrial and Nuclear Genes
... chloroplast DNA and mtDNA and to obtain recombinant mitochondrial genomes (reviewed by Hanson, 1984). Analysis of somatic hybrids between CMS and fertile protoplast parents has shown that fertility does not segregate with the chloroplast DNA. In Petunia and Brassica, lines that contain recombinant m ...
... chloroplast DNA and mtDNA and to obtain recombinant mitochondrial genomes (reviewed by Hanson, 1984). Analysis of somatic hybrids between CMS and fertile protoplast parents has shown that fertility does not segregate with the chloroplast DNA. In Petunia and Brassica, lines that contain recombinant m ...
SNP - Asia University, Taiwan
... another. As migration is a potent (有效的) source of diversity, isolation affects the rate at which variation is lost (i.e. no variation) due to drift. • Nucleotide Diversity - the average fraction of nucleotides that differ between a pair of alleles chosen at random from a population • Hs – lower nucl ...
... another. As migration is a potent (有效的) source of diversity, isolation affects the rate at which variation is lost (i.e. no variation) due to drift. • Nucleotide Diversity - the average fraction of nucleotides that differ between a pair of alleles chosen at random from a population • Hs – lower nucl ...
Genetic enhancers
... 4. Enhancement of mutations in homologous genes Null or near-null mutations were identified in three genes that encode different kinetic classes of acetylcholinesterase (Culotti et al., 1981; Johnson et al., 1981; Johnson et al., 1988). Single mutants and ace-1 ace-3 and ace-2 ace-3 double mutants e ...
... 4. Enhancement of mutations in homologous genes Null or near-null mutations were identified in three genes that encode different kinetic classes of acetylcholinesterase (Culotti et al., 1981; Johnson et al., 1981; Johnson et al., 1988). Single mutants and ace-1 ace-3 and ace-2 ace-3 double mutants e ...
Reconstruction of a Functional Human Gene Network, with an
... Most common genetic disorders have a complex inheritance and may result from variants in many genes, each contributing only weak effects to the disease. Pinpointing these disease genes within the myriad of susceptibility loci identified in linkage studies is difficult because these loci may contain ...
... Most common genetic disorders have a complex inheritance and may result from variants in many genes, each contributing only weak effects to the disease. Pinpointing these disease genes within the myriad of susceptibility loci identified in linkage studies is difficult because these loci may contain ...
Lecture 7: Gene Finding by Computational Analysis Gene
... • Relative freq of a dicodon in coding vs non-coding – Freq of dicodon X (e.g, AAA AAA) in coding region = total number of occurrences of X divided by total number of dicodon occurrences – Freq of dicodon X (e.g, AAA AAA) in noncoding region = total number of occurrences of X divided by total number ...
... • Relative freq of a dicodon in coding vs non-coding – Freq of dicodon X (e.g, AAA AAA) in coding region = total number of occurrences of X divided by total number of dicodon occurrences – Freq of dicodon X (e.g, AAA AAA) in noncoding region = total number of occurrences of X divided by total number ...
A Predictive Based Regression Algorithm for Gene Network
... According to our understanding of the problem (i.e. single model based on likelihood methods): YES! However: Focusing on a single model suggests a level of confidence in our final result that is not justified by the data as other models generally exist with similar good fit (Whittingham et al., 2006 ...
... According to our understanding of the problem (i.e. single model based on likelihood methods): YES! However: Focusing on a single model suggests a level of confidence in our final result that is not justified by the data as other models generally exist with similar good fit (Whittingham et al., 2006 ...
Sex Chromosome Dosage Effects On Gene Expression In
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
New Construct Approaches for Efficient Gene Silencing in Plants
... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...
... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...
PDF
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
... reverse transcription polymerase chain reaction (qPCR) measures of expression for genes of interest identified in our core sample (Table S1, Material and Methods). To first verify our study design as a tool for probing SCD effects on gene expression, and to identify core SCD-sensitive genes, we scre ...
How does chromosome behavior account for Mendel`s Principles ?
... A geneticist wants to map the position of three dominant/recessive allele pairs (A/a, B/b, and F/f) relative to each other in D. melanogaster (fruit flies). For simplicity let’s say all the dominant alleles are on the same chromosome. Where should she begin? 1. Do AaBb x aabb and look for recombinan ...
... A geneticist wants to map the position of three dominant/recessive allele pairs (A/a, B/b, and F/f) relative to each other in D. melanogaster (fruit flies). For simplicity let’s say all the dominant alleles are on the same chromosome. Where should she begin? 1. Do AaBb x aabb and look for recombinan ...
Online supplement: references - Evidence
... Of 33 studies that have examined this relationship since then, 17 have examined whether this relationship is indeed greater than multiplicative. Of these, only 2 find a pattern of interaction consistent with that in the originally study (2, 3) (1 of these in a sub-group only (2)), 8 find evidence of ...
... Of 33 studies that have examined this relationship since then, 17 have examined whether this relationship is indeed greater than multiplicative. Of these, only 2 find a pattern of interaction consistent with that in the originally study (2, 3) (1 of these in a sub-group only (2)), 8 find evidence of ...
The codon adaptation index-a measure of directional synonymous
... for locating genes in sequenced DNA, for predicting the relative level of their expression, and for detecting sequencing errors. However, the statistic is not normalized and therefore the values for two genes encoding proteins with different araino acid compositions can be quite different even if bo ...
... for locating genes in sequenced DNA, for predicting the relative level of their expression, and for detecting sequencing errors. However, the statistic is not normalized and therefore the values for two genes encoding proteins with different araino acid compositions can be quite different even if bo ...
BMC Evolutionary Biology D- and L-lactate dehydrogenases during invertebrate evolution
... enzyme. This hypothesis emerged from phylogenetic reconstructions and from the observation that the single LDH isozyme of the primitive agnathan, the sea lamprey, is immunologically more similar to LDH-C in teleost fish than to LDH-A or LDH-B [14-16]. Our phylogenetic analyses of L-LDH isozymes are ...
... enzyme. This hypothesis emerged from phylogenetic reconstructions and from the observation that the single LDH isozyme of the primitive agnathan, the sea lamprey, is immunologically more similar to LDH-C in teleost fish than to LDH-A or LDH-B [14-16]. Our phylogenetic analyses of L-LDH isozymes are ...
Mutations in SIN4 and RGR1 Cause Constitutive Expression of MAL
... the maltose-binding sensor. Alternatively, other positive or negative regulators may be involved but may not have been identified as yet because they are encoded by repeated or essential genes. To identify possible additional players involved in regulating MAL gene expression, we designed a sensitiv ...
... the maltose-binding sensor. Alternatively, other positive or negative regulators may be involved but may not have been identified as yet because they are encoded by repeated or essential genes. To identify possible additional players involved in regulating MAL gene expression, we designed a sensitiv ...
- Philsci
... functions, developmental pathways, mechanisms, or structures which are required by a variety of species which present the same homological genes, proteins or gene sequences. Those sequences which are conserved between species are more likely to have functions than those genetic sequences which have ...
... functions, developmental pathways, mechanisms, or structures which are required by a variety of species which present the same homological genes, proteins or gene sequences. Those sequences which are conserved between species are more likely to have functions than those genetic sequences which have ...
The dystrophin / utrophin homologues in Drosophila and in sea urchin
... further downstream in the huge DMD gene regulate the expression of smaller products. Dp71, a 70.8 kDa protein, consists of only the cysteine-rich and C-terminal domains of dystrophin (Bar et al., 1990; Lederfein et al., 1992). It is the most abundant non-muscle product of the DMD gene. The highest l ...
... further downstream in the huge DMD gene regulate the expression of smaller products. Dp71, a 70.8 kDa protein, consists of only the cysteine-rich and C-terminal domains of dystrophin (Bar et al., 1990; Lederfein et al., 1992). It is the most abundant non-muscle product of the DMD gene. The highest l ...
Self-Subunit Swapping Occurs in Another Gene Type of Cobalt
... enzyme properties, gene organizations, etc.) shared among these cobalt-containing enzymes [30]. NHase in Pseudomonas putida NRRL-18668 and acetonitrile hydratase (ANHase, an NHase that catalyzes the hydration of small aliphatic nitriles) from Rhodococcus jostii RHA1 are also CoNHases in which P14K a ...
... enzyme properties, gene organizations, etc.) shared among these cobalt-containing enzymes [30]. NHase in Pseudomonas putida NRRL-18668 and acetonitrile hydratase (ANHase, an NHase that catalyzes the hydration of small aliphatic nitriles) from Rhodococcus jostii RHA1 are also CoNHases in which P14K a ...
Tumour necrosis factor α -308G/A gene polymorphism
... have been too small to be detected in the present study sample, and a larger sample size may be required. Alternatively, a possible association may have been weakened by disease heterogeneity, environmental factors or gene-environment interactions. In fact, linkage disequilibrium is strong in this a ...
... have been too small to be detected in the present study sample, and a larger sample size may be required. Alternatively, a possible association may have been weakened by disease heterogeneity, environmental factors or gene-environment interactions. In fact, linkage disequilibrium is strong in this a ...
Text S1.
... molecular evolution studies of the S-locus in Brassicaceae (e.g. [23]). Hence, these two pairs of sequences are certainly corresponding to four distinct S-alleles present in the common ancestor of both A. halleri and A. lyrata. ...
... molecular evolution studies of the S-locus in Brassicaceae (e.g. [23]). Hence, these two pairs of sequences are certainly corresponding to four distinct S-alleles present in the common ancestor of both A. halleri and A. lyrata. ...