use of genomic tools to discover the cause of
... Three sire families were identified as segregating for this trait. Genome wide linkage analysis using 104 microsatellite DNA markers was used to map the gene to ECA14 (LOD > 11.0). Four genes, namely SPARC, SLC36A1, SLC36A2 and SLC36A3, were selected from the region implicated by linkage and their e ...
... Three sire families were identified as segregating for this trait. Genome wide linkage analysis using 104 microsatellite DNA markers was used to map the gene to ECA14 (LOD > 11.0). Four genes, namely SPARC, SLC36A1, SLC36A2 and SLC36A3, were selected from the region implicated by linkage and their e ...
Text S1.
... molecular evolution studies of the S-locus in Brassicaceae (e.g. [23]). Hence, these two pairs of sequences are certainly corresponding to four distinct S-alleles present in the common ancestor of both A. halleri and A. lyrata. ...
... molecular evolution studies of the S-locus in Brassicaceae (e.g. [23]). Hence, these two pairs of sequences are certainly corresponding to four distinct S-alleles present in the common ancestor of both A. halleri and A. lyrata. ...
Molecular Genetics of Alcohol-Related Brain Damage
... Several mechanisms have been implicated in the pathogenesis of thiamine deficiency such as oxidative stress, glutamatemediated excitotoxicity and focal lactic acidosis. Hazell and colleagues extensively studied the role of glutamate neurotoxicity triggered by thiamine deficiency. Their findings show ...
... Several mechanisms have been implicated in the pathogenesis of thiamine deficiency such as oxidative stress, glutamatemediated excitotoxicity and focal lactic acidosis. Hazell and colleagues extensively studied the role of glutamate neurotoxicity triggered by thiamine deficiency. Their findings show ...
Recombination and clonal groupings within Helicobacter pylori from
... bacteria from different continents or that particular alleles are selected for in certain populations. However, a different segment of the vacA gene was found to have recombined freely in bacteria isolated from Canada and South Africa (Suerbaum et al ., 1998). The virulence-associated cagA gene enco ...
... bacteria from different continents or that particular alleles are selected for in certain populations. However, a different segment of the vacA gene was found to have recombined freely in bacteria isolated from Canada and South Africa (Suerbaum et al ., 1998). The virulence-associated cagA gene enco ...
REVIEW Mouse models of human disease. Part I: Techniques and
... been developed primarily for the study of cancer (Fijneman et al. 1995; Lipoldova et al. 1995; Moen et al. 1996), they can also be used to study numerous other diseases as well. It is important to note, however, that genetic analysis in RC strains still suffers many of the same limitations as analys ...
... been developed primarily for the study of cancer (Fijneman et al. 1995; Lipoldova et al. 1995; Moen et al. 1996), they can also be used to study numerous other diseases as well. It is important to note, however, that genetic analysis in RC strains still suffers many of the same limitations as analys ...
CHAPTER 5 General discussion - UvA-DARE
... suggestingg that genetically diverse regions were present. 2) We observed that fusion productss initially contained both hph and ble genes, but eventually lost the phleomycin markerr (Chapter 4, Fig. 3A). The loss of the ble marker might be the result of nondisjunctionall haploidization. Sincee hapl ...
... suggestingg that genetically diverse regions were present. 2) We observed that fusion productss initially contained both hph and ble genes, but eventually lost the phleomycin markerr (Chapter 4, Fig. 3A). The loss of the ble marker might be the result of nondisjunctionall haploidization. Sincee hapl ...
- Genetics
... 2013), we mapped several genes to the S. latifolia PAR. The 25-cM genetic map length of the S. latifolia PAR suggests that it probably carries many genes that could potentially undergo SA mutations, and so this species is well suited for testing the SA hypothesis, unlike species whose PARs include ...
... 2013), we mapped several genes to the S. latifolia PAR. The 25-cM genetic map length of the S. latifolia PAR suggests that it probably carries many genes that could potentially undergo SA mutations, and so this species is well suited for testing the SA hypothesis, unlike species whose PARs include ...
Friesland Foods Normal
... literature (57, 76, 77). Both HMMs were used to scan the selected genomes (cut-off e-value 1 (37)) and the locations of putative boxes were identified. The amino acid specificity of the detected T-boxes was established on basis of the specifier codon as described by Wels et al. (77) and exemplified ...
... literature (57, 76, 77). Both HMMs were used to scan the selected genomes (cut-off e-value 1 (37)) and the locations of putative boxes were identified. The amino acid specificity of the detected T-boxes was established on basis of the specifier codon as described by Wels et al. (77) and exemplified ...
Part 4 Student Handout - URMC
... Testing for the HD Gene Narrator: Jenny, Jeremy, and their father have decided to undergo genetic testing for Huntington’s disease. Today, our lab groups will act as gene testing laboratory technicians. We will use the gel electrophoresis laboratory procedure to analyze the results of the simulated ...
... Testing for the HD Gene Narrator: Jenny, Jeremy, and their father have decided to undergo genetic testing for Huntington’s disease. Today, our lab groups will act as gene testing laboratory technicians. We will use the gel electrophoresis laboratory procedure to analyze the results of the simulated ...
Genes for Two Mitochondrial Ribosomal Proteins in
... clade of mitochondrially located rps13 genes. Together, these results clearly indicate that the numit rps13 genes of angiosperms are derived via duplication and substitution from the nucp rps13 rather than from a recent transfer of mitochondrial rps13 to the nucleus. The predicted targeting sequence ...
... clade of mitochondrially located rps13 genes. Together, these results clearly indicate that the numit rps13 genes of angiosperms are derived via duplication and substitution from the nucp rps13 rather than from a recent transfer of mitochondrial rps13 to the nucleus. The predicted targeting sequence ...
Click
... databases are interlinked, and it is possible to readily move between databases to mine all types of data from NCBI. Once you have found the gene that you are interested from either from an ENTREZ search or an OMIM search, you should now be able to navigate to: 1) find the RefSeq for the gene and al ...
... databases are interlinked, and it is possible to readily move between databases to mine all types of data from NCBI. Once you have found the gene that you are interested from either from an ENTREZ search or an OMIM search, you should now be able to navigate to: 1) find the RefSeq for the gene and al ...
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
... some seems to be typical of the large yeast chromosomes, and shows large duplications with other yeast chromosomes. Chromosome XVI contains 487 potential protein-encoding genes, 17 tRNA genes and two small nuclear RNA genes; 27% of the genes have significant similarities to human gene products, and ...
... some seems to be typical of the large yeast chromosomes, and shows large duplications with other yeast chromosomes. Chromosome XVI contains 487 potential protein-encoding genes, 17 tRNA genes and two small nuclear RNA genes; 27% of the genes have significant similarities to human gene products, and ...
Rye SCAR markers for male fertility restoration in the P cytoplasm
... The combined linkage map comprising F2 and BC1 segregation data (Figure 1) contains 3 SCAR markers located in the interval between RAPD markers pr23/500 bp and pr743/750 bp, flanking the Rfc1 gene according to a previous study (Stoja³owski et al. 2004b). A strong linkage of the SCAR markers with the ...
... The combined linkage map comprising F2 and BC1 segregation data (Figure 1) contains 3 SCAR markers located in the interval between RAPD markers pr23/500 bp and pr743/750 bp, flanking the Rfc1 gene according to a previous study (Stoja³owski et al. 2004b). A strong linkage of the SCAR markers with the ...
Application of rpoB sequence similarity analysis, REP‐PCR and
... and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement with Zeigler (2005) who confirmed 16S rRNA gene sequences similarity of Geobacillus type strains, higher than 98Æ5%. Despite the general use of the 16S rRNA gene as framework for modern bacteria ...
... and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement with Zeigler (2005) who confirmed 16S rRNA gene sequences similarity of Geobacillus type strains, higher than 98Æ5%. Despite the general use of the 16S rRNA gene as framework for modern bacteria ...
Using Mice to Dissect Genetic Factors in Atherosclerosis
... the distribution of a trait (eg, atherosclerosis) in the strains from 1 RI set of animals with the distribution of the polymorphic genetic markers already typed for those strains, chromosomal loci that segregate with the trait of interest can be identified. In general, RI mapping has had low power a ...
... the distribution of a trait (eg, atherosclerosis) in the strains from 1 RI set of animals with the distribution of the polymorphic genetic markers already typed for those strains, chromosomal loci that segregate with the trait of interest can be identified. In general, RI mapping has had low power a ...
Reliable classification of two-class cancer data using evolutionary
... In the area of bioinformatics, the identification of gene subsets responsible for classifying available disease samples to two or more of its variants is an important task. Such problems have been solved in the past by means of unsupervised learning methods (hierarchical clustering, self-organizing ...
... In the area of bioinformatics, the identification of gene subsets responsible for classifying available disease samples to two or more of its variants is an important task. Such problems have been solved in the past by means of unsupervised learning methods (hierarchical clustering, self-organizing ...
Genetics Exercise - Holy Trinity Academy
... 2. In humans, normal pigmentation dominates no pigmentation (albino). Black hair dominates blonde hair. An albino person will have white hair color even though they may also have the genes for black or blonde hair colour. An albino male who is homozygous for black hair marries a woman who is heteroz ...
... 2. In humans, normal pigmentation dominates no pigmentation (albino). Black hair dominates blonde hair. An albino person will have white hair color even though they may also have the genes for black or blonde hair colour. An albino male who is homozygous for black hair marries a woman who is heteroz ...
Genetica per Scienze Naturali aa 04
... 1. Hemoglobinopathies Hemoglobinopathies occupy a special place in human genetics for many reasons: ...
... 1. Hemoglobinopathies Hemoglobinopathies occupy a special place in human genetics for many reasons: ...
The dual nature of homologous recombination in plants
... processes of life. It has a dual function through its activities both in meiosis and in somatic cells. It creates new linkages in the genetic material in meiosis and in many organisms it is even required for fertility. Indeed, HR substantially contributes to evolution. HR is also important for repai ...
... processes of life. It has a dual function through its activities both in meiosis and in somatic cells. It creates new linkages in the genetic material in meiosis and in many organisms it is even required for fertility. Indeed, HR substantially contributes to evolution. HR is also important for repai ...
The human Y chromosome: a sole survivor Noordam, MJ - UvA-DARE
... recombination between palindromes. We screened 1,237 men that originated from a previous study (Repping et al., 2003) or from a consecutive cohort of men that attended the Center for Reproductive Medicine of the Academic Medical Center as part of an infertile couple. We identified eight unrelated me ...
... recombination between palindromes. We screened 1,237 men that originated from a previous study (Repping et al., 2003) or from a consecutive cohort of men that attended the Center for Reproductive Medicine of the Academic Medical Center as part of an infertile couple. We identified eight unrelated me ...
Functional significance of the discordance between
... LV remodeling following mechanical circulatory support. Persistence of the HF gene program was associated with an exaggerated hypertrophic response and increased mortality in tTA-TRAF2dox4W mice following transaortic constriction (TAC). These effects were no longer observed following TAC in tTA-TRAF ...
... LV remodeling following mechanical circulatory support. Persistence of the HF gene program was associated with an exaggerated hypertrophic response and increased mortality in tTA-TRAF2dox4W mice following transaortic constriction (TAC). These effects were no longer observed following TAC in tTA-TRAF ...
Evolution of RH Genes in Hominoids: Characterization of a Gorilla
... and RhcE polypeptides were 29 and 25, respectively ( Table 2). Differences between gorilla RHCE-like polypeptide and two other gorilla Rh-like polypeptides were almost identical (24 and 25, respectively) ( Table 2). The topology of the phylogenetic tree obtained from the alignment shown in Figure 4 ...
... and RhcE polypeptides were 29 and 25, respectively ( Table 2). Differences between gorilla RHCE-like polypeptide and two other gorilla Rh-like polypeptides were almost identical (24 and 25, respectively) ( Table 2). The topology of the phylogenetic tree obtained from the alignment shown in Figure 4 ...
HTR1A a Novel Type 1 Diabetes Susceptibility
... from the cohort. In the current study we have included 2300 T1D patients from the BDD cohort. Multiple Sclerosis (MS) controls. We have included 527 healthy controls between the ages of 18–70 years from an ongoing population based case control study of multiple sclerosis (MS) called EIMS (Epidemiolo ...
... from the cohort. In the current study we have included 2300 T1D patients from the BDD cohort. Multiple Sclerosis (MS) controls. We have included 527 healthy controls between the ages of 18–70 years from an ongoing population based case control study of multiple sclerosis (MS) called EIMS (Epidemiolo ...
Thesis-1962R-S215s
... human inheritance by studying family pedigrees. From this information they can prediet how a certs.in· :trai t or characteristic is inherited.. This study is an accumulation of mater.ial that will help to introduce to capable high school students some or the work in human heredity tha.t has been don ...
... human inheritance by studying family pedigrees. From this information they can prediet how a certs.in· :trai t or characteristic is inherited.. This study is an accumulation of mater.ial that will help to introduce to capable high school students some or the work in human heredity tha.t has been don ...
Rebuttal - MIT Technology Review
... No: gene expression changes either are compensatory responses to other, non-genetic changes – and thus will typically revert when the latter are reversed as SENS proposes5 – or are caused by epimutations (random, stochastic changes in DNA methylation or histone modification), whose incidence is kept ...
... No: gene expression changes either are compensatory responses to other, non-genetic changes – and thus will typically revert when the latter are reversed as SENS proposes5 – or are caused by epimutations (random, stochastic changes in DNA methylation or histone modification), whose incidence is kept ...