genetics genetics - Cystic Fibrosis Association of New Zealand
... help clear the mucus from the lungs, antibiotics to fight infection, and enzyme supplements with food to help digestion. Although new treatments are being developed, which will undoubtedly improve the quality and length of life for people with CF, the condition remains serious. There is no cure at p ...
... help clear the mucus from the lungs, antibiotics to fight infection, and enzyme supplements with food to help digestion. Although new treatments are being developed, which will undoubtedly improve the quality and length of life for people with CF, the condition remains serious. There is no cure at p ...
X chromosome inactivation- Review
... region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always inactivated in females ...
... region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always inactivated in females ...
Repair of Site-Specific DNA Double-Strand Breaks in
... 2005). Therefore, we presume I-SceI nuclease activity in all somatic cells and cleavage of nearly all recognition sites. The breaks in reads with the original I-SceI site would have been repaired, restoring the site, by either immediate ligation or by precise SCE. Distinguishing between these two ty ...
... 2005). Therefore, we presume I-SceI nuclease activity in all somatic cells and cleavage of nearly all recognition sites. The breaks in reads with the original I-SceI site would have been repaired, restoring the site, by either immediate ligation or by precise SCE. Distinguishing between these two ty ...
Chapter 4 Extension Activity
... When solving genetic problems that involve sex-linkage, the symbols X and Y are used, but these differ from other genetic problems because X and Y are not symbols for genes, they represent whole chromosomes. These sex chromosomes do not only carry genes that control sexual development, they have oth ...
... When solving genetic problems that involve sex-linkage, the symbols X and Y are used, but these differ from other genetic problems because X and Y are not symbols for genes, they represent whole chromosomes. These sex chromosomes do not only carry genes that control sexual development, they have oth ...
Obesity — a genetic disease of adipose tissue?
... gene–environment interactions is given in Fig. 1. One of these genes may be a major one and the others could be minor obesity genes. The particular major and minor obesity genes may differ between families or ethnic groups. In the rest of this paper I discuss the relative importance of genes with a ...
... gene–environment interactions is given in Fig. 1. One of these genes may be a major one and the others could be minor obesity genes. The particular major and minor obesity genes may differ between families or ethnic groups. In the rest of this paper I discuss the relative importance of genes with a ...
Full-Text PDF
... ε-ionone rings in the crucial bifurcation step of carotenoid biosynthesis. Among all carotenoid constituents, β-carotene (β,β-carotene) is found in all photosynthetic organisms, except for purple bacteria and heliobacteria, suggesting a ubiquitous distribution of lycopene β-cyclase activity in these ...
... ε-ionone rings in the crucial bifurcation step of carotenoid biosynthesis. Among all carotenoid constituents, β-carotene (β,β-carotene) is found in all photosynthetic organisms, except for purple bacteria and heliobacteria, suggesting a ubiquitous distribution of lycopene β-cyclase activity in these ...
Genetic Testing and Molecular Diagnostics
... Genetic testing is testing performed to detect changes or mutations in DNA, RNA, chromosomes, proteins, or certain metabolites. Genetic testing may be performed for several different purposes, including, but not limited to, diagnosing or predicting susceptibility for inherited conditions, screening ...
... Genetic testing is testing performed to detect changes or mutations in DNA, RNA, chromosomes, proteins, or certain metabolites. Genetic testing may be performed for several different purposes, including, but not limited to, diagnosing or predicting susceptibility for inherited conditions, screening ...
![Spectrum of [beta] thalassemia mutations and HbF levels in the](http://s1.studyres.com/store/data/014164939_1-79827c78cbc8128eaad3fd6fece2f656-300x300.png)
First genomic insights into members of a candidate bacterial
... UniRef90 (Suzek et al., 2007), IMG (Integrated Microbial Genomes, finished genomes, release 4.0) (Markowitz et al., 2014), COGs (Clusters of Orthologous Groups) (Tatusov et al., 2000), PFAM (Punta et al., 2012), and KEGG (Kyoto Encyclopedia of Genes and Genomes) (Aoki-Kinoshita & Kanehisa, 2007) dat ...
... UniRef90 (Suzek et al., 2007), IMG (Integrated Microbial Genomes, finished genomes, release 4.0) (Markowitz et al., 2014), COGs (Clusters of Orthologous Groups) (Tatusov et al., 2000), PFAM (Punta et al., 2012), and KEGG (Kyoto Encyclopedia of Genes and Genomes) (Aoki-Kinoshita & Kanehisa, 2007) dat ...
Control of GL2 expression in Arabidopsis leaves and trichomes
... GL2 protein appears to show celltype specific subcellular localization in developing leaves, and is localized in the nucleus in developing trichomes Both GL1 and TTG may directly bind to the GL2 promoter, either alone or as part of a larger complex, but the interaction between GL1 and R somehow elim ...
... GL2 protein appears to show celltype specific subcellular localization in developing leaves, and is localized in the nucleus in developing trichomes Both GL1 and TTG may directly bind to the GL2 promoter, either alone or as part of a larger complex, but the interaction between GL1 and R somehow elim ...
Lactobacilli carry cryptic genes encoding peptidase
... Two genes, pepQ and orf2, encoding a prolidase and a prolidase-like protein, respectively, were cloned and characterized from Lactobacillus delbrueckii subsp. bulgaricus. The identity of the pepQ and orfZ genes with the Lactobacillus delbrueckii subsp. lactis prolidase gene (pepQ) was shown to be 98 ...
... Two genes, pepQ and orf2, encoding a prolidase and a prolidase-like protein, respectively, were cloned and characterized from Lactobacillus delbrueckii subsp. bulgaricus. The identity of the pepQ and orfZ genes with the Lactobacillus delbrueckii subsp. lactis prolidase gene (pepQ) was shown to be 98 ...
- Philsci-Archive
... under which the explanandum-outcome would have been different, that is, information about changes that (“in principle, and assuming we were able to perform them) might be used to manipulate or control the outcome. More generally, successful causal explanation consists in the exhibition of patterns o ...
... under which the explanandum-outcome would have been different, that is, information about changes that (“in principle, and assuming we were able to perform them) might be used to manipulate or control the outcome. More generally, successful causal explanation consists in the exhibition of patterns o ...
Anterior boundaries of Hox gene expression in mesoderm
... 11 days of gestation, Hox 1.1 is still more posterior than Hox 1.2. Hox 1.1 expression in mesodermderived tissues is limited to the metanephros, as described previously [37]. Interestingly, Hox 3.1 expression at 12 days of gestation is even more posterior, beginning at the sixth thoracic prevertebra ...
... 11 days of gestation, Hox 1.1 is still more posterior than Hox 1.2. Hox 1.1 expression in mesodermderived tissues is limited to the metanephros, as described previously [37]. Interestingly, Hox 3.1 expression at 12 days of gestation is even more posterior, beginning at the sixth thoracic prevertebra ...
1 Sequential elimination of major-effect contributors
... loci, many of these strategies have had poor success rates, potentially due to the confounding effects of major loci and epistasis. Therefore, to avoid confounding effects of major loci, epistasis and sample size, we used a targeted backcross mapping strategy that genetically eliminated the effect o ...
... loci, many of these strategies have had poor success rates, potentially due to the confounding effects of major loci and epistasis. Therefore, to avoid confounding effects of major loci, epistasis and sample size, we used a targeted backcross mapping strategy that genetically eliminated the effect o ...
PDF
... Background: Several studies have investigated the relationships between selective constraints in introns and their length, GC content and location within genes. To date, however, no such investigation has been done in plants. Studies of selective constraints in noncoding DNA have generally involved ...
... Background: Several studies have investigated the relationships between selective constraints in introns and their length, GC content and location within genes. To date, however, no such investigation has been done in plants. Studies of selective constraints in noncoding DNA have generally involved ...
Bacteroides mobilizable and conjugative genetic elements
... decrease in protein production. TetQ is a ribosome protection type of tetracycline resistance protein, which is most closely related to an elongation factor. TetQ modifies ribosomes so that tetracycline no longer binds as efficiently. The fact that a higher intracellular concentration of TetQ increa ...
... decrease in protein production. TetQ is a ribosome protection type of tetracycline resistance protein, which is most closely related to an elongation factor. TetQ modifies ribosomes so that tetracycline no longer binds as efficiently. The fact that a higher intracellular concentration of TetQ increa ...
Leukaemia Section del(17p) in myeloïd malignancies Atlas of Genetics and Cytogenetics
... Phenotype/cell stem origin Mainly refractory anemia with excess of blasts RAEB/RAEB-t in MDS, often M2 or M6 in ANLL / ...
... Phenotype/cell stem origin Mainly refractory anemia with excess of blasts RAEB/RAEB-t in MDS, often M2 or M6 in ANLL / ...
Some Calpain History- Part 2: GENETICS and EVOLUTION
... The information for calpain genetics is organized by genes for component subunits of calpain-1 (Capn1 and Capns1), calpain-2 (Capn2 and Capns1) and calpastatin (Cast) Capn3 – a genetic link to human disease- Limb-Girdle Muscular Dystrophy type IIA Capn10- a genetic link to human disease- type ...
... The information for calpain genetics is organized by genes for component subunits of calpain-1 (Capn1 and Capns1), calpain-2 (Capn2 and Capns1) and calpastatin (Cast) Capn3 – a genetic link to human disease- Limb-Girdle Muscular Dystrophy type IIA Capn10- a genetic link to human disease- type ...
Identification and Analysis of Arabidopsis Expressed Sequence
... of this family. This transcript was first identified as one of the most unstable transcripts in tobacco (Nicotiana tabacum) cell cultures (Taylor and Green, 1995). The fact that transcripts of this family are hormonally regulated and have unstable transcripts suggest that they may play a role in reg ...
... of this family. This transcript was first identified as one of the most unstable transcripts in tobacco (Nicotiana tabacum) cell cultures (Taylor and Green, 1995). The fact that transcripts of this family are hormonally regulated and have unstable transcripts suggest that they may play a role in reg ...
Package ‘GenomicFeatures’ October 14, 2014
... functions for making your own custom TxDb object from various annotation resources. • The BSgenome, TwoBitFile, and FaFile classes, defined and documented in the BSgenome, rtracklayer, and Rsamtools packages, respectively. • The TxDb class. • The genes function for extracting gene ranges from a TxDb ...
... functions for making your own custom TxDb object from various annotation resources. • The BSgenome, TwoBitFile, and FaFile classes, defined and documented in the BSgenome, rtracklayer, and Rsamtools packages, respectively. • The TxDb class. • The genes function for extracting gene ranges from a TxDb ...
RNA interference pathways display high rates of adaptive protein
... population-genetic model to estimate the number of adaptive nonsynonymous substitutions per site (DFEalpha) (Eyre-Walker & Keightley, 2009). This approach has the advantage that it provides direct estimates of the parameters of interest, and explicitly models changes in population size and the distr ...
... population-genetic model to estimate the number of adaptive nonsynonymous substitutions per site (DFEalpha) (Eyre-Walker & Keightley, 2009). This approach has the advantage that it provides direct estimates of the parameters of interest, and explicitly models changes in population size and the distr ...
Can transgenic mosquitoes afford the fitness cost? - MiVEGEC
... of carrying the transgene will be considerably lower. Furthermore, in an epidemiological context, any fitness advantage conferred by the transgene decreases progressively when its frequency rises because increased resistance reduces the rate of disease transmission and thus the probability that a mo ...
... of carrying the transgene will be considerably lower. Furthermore, in an epidemiological context, any fitness advantage conferred by the transgene decreases progressively when its frequency rises because increased resistance reduces the rate of disease transmission and thus the probability that a mo ...