The trp Operon - aandersonbiology
... Modeling Gene Regulation Cells in the skin on your fingers have the same genetic information as the cells in your pancreas, yet your finger cells do not produce insulin. How do pancreatic cells “know” to produce insulin? The basic answer to this question lies in the fact that genetic information is ...
... Modeling Gene Regulation Cells in the skin on your fingers have the same genetic information as the cells in your pancreas, yet your finger cells do not produce insulin. How do pancreatic cells “know” to produce insulin? The basic answer to this question lies in the fact that genetic information is ...
Determining presence/absence threshold for your dataset
... In PanCGHweb there are two ways to determine the presence/absence calling threshold. One is based on Receiver Operating Curves (ROC) generated for microarray data of reference strains and the other is based on plotting histograms of presence of scores for ortholog groups of reference strains. Note: ...
... In PanCGHweb there are two ways to determine the presence/absence calling threshold. One is based on Receiver Operating Curves (ROC) generated for microarray data of reference strains and the other is based on plotting histograms of presence of scores for ortholog groups of reference strains. Note: ...
ABSTRACT Using a bioinformatics approach to identify genes that
... categorizations. While public users can enter a gene set into GeneWeaver, most gene sets are derived directly from experimentation (GWAS, Microarray, etc.) or publications. For example, PubMed, a database for scientific literature, can be used to find articles that describe gene sets, and these gene ...
... categorizations. While public users can enter a gene set into GeneWeaver, most gene sets are derived directly from experimentation (GWAS, Microarray, etc.) or publications. For example, PubMed, a database for scientific literature, can be used to find articles that describe gene sets, and these gene ...
Exploring Tomato Gene Functions Based on Coexpression Modules
... crops (Ogata et al., 2010; Tohge and Fernie, 2010). These data make it possible to use gene coexpression analyses to predict unknown gene functions (Aoki et al., 2007; Usadel et al., 2009). Using pair-wise measures, e.g. Pearson’s correlation coefficient, it is possible to generate a coexpression ne ...
... crops (Ogata et al., 2010; Tohge and Fernie, 2010). These data make it possible to use gene coexpression analyses to predict unknown gene functions (Aoki et al., 2007; Usadel et al., 2009). Using pair-wise measures, e.g. Pearson’s correlation coefficient, it is possible to generate a coexpression ne ...
Boundary elements and nuclear organization
... recruitment of specific activities to a limited locus, or targeting to a subnuclear compartment associated with either silencing or activation. All of these mechanisms may involve the action of specialized regulatory elements, which phenotypically would behave as chromatin domain boundaries. Such el ...
... recruitment of specific activities to a limited locus, or targeting to a subnuclear compartment associated with either silencing or activation. All of these mechanisms may involve the action of specialized regulatory elements, which phenotypically would behave as chromatin domain boundaries. Such el ...
Genome-Wide Identification of Allelic Expression in Hypertensive
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
... Genomic SSLP data were available for 2 SHR lines (SHR/OlaHsd and SHRSP/Riv) and 1 WKY line (WKY/OlaHsd). These lines are closely related to, and may be identical to, the SHR/NCrl, SHR-A3, and WKY/NCrl lines, respectively, used in our studies. We used this data to assess the degree of allelic identit ...
Identification of chromosome intervals from 129 and C57BL/6 mouse
... has been inactivated in 129 embryonic stem cells, also developed an autoimmune phenotype. The humoral autoimmunity in this congenic strain was indistinguishable to that observed in a mouse carrying a deletion of the Apcs gene, located within the lupus-linked genomic region on distal chromosome 1 and ...
... has been inactivated in 129 embryonic stem cells, also developed an autoimmune phenotype. The humoral autoimmunity in this congenic strain was indistinguishable to that observed in a mouse carrying a deletion of the Apcs gene, located within the lupus-linked genomic region on distal chromosome 1 and ...
Y chromosome azoospermia factor region microdeletions and
... demonstrated to be is testis-specific, so it is reasonable to hypothesize that RPS4Y2 may potentially play a role in posttranscriptional regulation of the spermatogenic program [33]. The CYORF15A and CYORF15B sequences belong to the taxilin family and are involved in transcriptional regulation in os ...
... demonstrated to be is testis-specific, so it is reasonable to hypothesize that RPS4Y2 may potentially play a role in posttranscriptional regulation of the spermatogenic program [33]. The CYORF15A and CYORF15B sequences belong to the taxilin family and are involved in transcriptional regulation in os ...
document
... Fig.3 bm3 zygosity determination with end-point TaqMan assay using KLIMs. A graph with RFU (relative fluorescence unit) of FAM as x-axis and VIC as y-axis was generated. Zygosity calls were made based on the cluster separation in a cluster view. ...
... Fig.3 bm3 zygosity determination with end-point TaqMan assay using KLIMs. A graph with RFU (relative fluorescence unit) of FAM as x-axis and VIC as y-axis was generated. Zygosity calls were made based on the cluster separation in a cluster view. ...
The SELF-PRUNING gene of tomato regulates
... because the ‘determinate’ growth habit facilitates mechanical harvest. A principal assumption of our work is that Arabidopsis, Antirrhinum and tomato employ similar genes to regulate their ...
... because the ‘determinate’ growth habit facilitates mechanical harvest. A principal assumption of our work is that Arabidopsis, Antirrhinum and tomato employ similar genes to regulate their ...
NIH Public Access
... which is the model acetogenic bacterium that has been widely used for elucidating the WoodLjungdahl pathway of CO and CO2 fixation. This pathway, which is also known as the reductive acetyl-CoA pathway, allows acetogenic (often called homoacetogenic) bacteria to convert glucose stoichiometrically in ...
... which is the model acetogenic bacterium that has been widely used for elucidating the WoodLjungdahl pathway of CO and CO2 fixation. This pathway, which is also known as the reductive acetyl-CoA pathway, allows acetogenic (often called homoacetogenic) bacteria to convert glucose stoichiometrically in ...
Mechanisms and constraints shaping the evolution of body plan
... outcomes and how these differ in frequency of occurrence and hence in likelihood of evolving. By subsequently varying for example developmental and gene expression noise, or fitness criterium we can also determine how these outcomes differ in robustness or future evolutionary potential. Finally, we can ...
... outcomes and how these differ in frequency of occurrence and hence in likelihood of evolving. By subsequently varying for example developmental and gene expression noise, or fitness criterium we can also determine how these outcomes differ in robustness or future evolutionary potential. Finally, we can ...
Comparative Genomics
... Tells us what is common and what is unique between different species at the genome level The function of human genes and other regions may be revealed by studying their counterparts in lower organisms Helps identify both coding and non-coding genes and regulatory elements ...
... Tells us what is common and what is unique between different species at the genome level The function of human genes and other regions may be revealed by studying their counterparts in lower organisms Helps identify both coding and non-coding genes and regulatory elements ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008, p-ISSN:2319-7676.
... The Progins Progesterone Receptor Gene Polymorphism and Polymorphism of the Estrogen … variants may influence cell proliferation, viability, and apoptosis in endometrial cell metabolism. Wieser et al., [14] Lattuada et al., [17] and Carvalho et al.[18] demonstrated a significant correlation between ...
... The Progins Progesterone Receptor Gene Polymorphism and Polymorphism of the Estrogen … variants may influence cell proliferation, viability, and apoptosis in endometrial cell metabolism. Wieser et al., [14] Lattuada et al., [17] and Carvalho et al.[18] demonstrated a significant correlation between ...
Title
... A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural doma ...
... A protein domain is a part of protein sequence and structure that can evolve, function, and exist independently of the rest of the protein chain. Each domain forms a compact three-dimensional structure and often can be independently stable and folded. Many proteins consist of several structural doma ...
The Interplay of Temperature and Genotype on Patterns
... While the selective advantage of both the presence or absence of phenotypic plasticity is conceptually appealing, their relative importance is not yet clear. Traditionally, plasticity has been studied using high-order phenotypes, such as morphology and life history traits, which integrate the effect ...
... While the selective advantage of both the presence or absence of phenotypic plasticity is conceptually appealing, their relative importance is not yet clear. Traditionally, plasticity has been studied using high-order phenotypes, such as morphology and life history traits, which integrate the effect ...
Transgenic approaches for optogenetics Tim Murphy UBC.
... (tetO) that expresses the transgene of interest. But what if you don’t have a tTA or rtTA transgenic mouse that targets your cell type, but you do have a Cre mouse with the right specificity? Mating Cre to B6.129P2(Cg)Gt(ROSA)26Sortm1(tTA)Roos/J (011008) or B6.Cg-Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J (0 ...
... (tetO) that expresses the transgene of interest. But what if you don’t have a tTA or rtTA transgenic mouse that targets your cell type, but you do have a Cre mouse with the right specificity? Mating Cre to B6.129P2(Cg)Gt(ROSA)26Sortm1(tTA)Roos/J (011008) or B6.Cg-Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/J (0 ...
mtr function Background Luis M. Corrochano
... spreading 0.2 ml of conidial suspension on the surface of the selective agar or by use of spreading agar with the appropriate supplements. The handling and plating of conidia should be performed in darkness or dim light to prevent photorepair. The plates should be incubated in the dark, at least for ...
... spreading 0.2 ml of conidial suspension on the surface of the selective agar or by use of spreading agar with the appropriate supplements. The handling and plating of conidia should be performed in darkness or dim light to prevent photorepair. The plates should be incubated in the dark, at least for ...
Network properties of human disease genes with pleiotropic effects
... of a node in a molecular network is often correlated to its centrality [14]. There are different measures that capture the centrality of a node in a network. We constructed a human protein interaction network using a modified version of CRG interactome [15] and investigated for differences in four d ...
... of a node in a molecular network is often correlated to its centrality [14]. There are different measures that capture the centrality of a node in a network. We constructed a human protein interaction network using a modified version of CRG interactome [15] and investigated for differences in four d ...
Molecular genetics of the extracellular lipase of
... The structural gene (&A) coding for the extracellularlipase of Pseudomonus aeruginusa PAOl has been cloned on plasmid pSW118. Nucleotide sequence analysis revealed a gene of 936 bp. 1ipA codes for a proenzyme of 311 amino acids including a leader sequence of 26 amino acids. The mature protein was pr ...
... The structural gene (&A) coding for the extracellularlipase of Pseudomonus aeruginusa PAOl has been cloned on plasmid pSW118. Nucleotide sequence analysis revealed a gene of 936 bp. 1ipA codes for a proenzyme of 311 amino acids including a leader sequence of 26 amino acids. The mature protein was pr ...
multicopy gene family evolution on primate y chromosomes
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
Expansion of the Pseudo-autosomal Region and Ongoing
... progress towards a complete genome sequence (International Human Genome Sequencing Consortium 2001). Eutherian PARs now include only a few genes (e.g., Van Laere et al. 2008), making it unlikely that SA polymorphisms will be found among them, so mammal PARs are no longer likely to be informative abo ...
... progress towards a complete genome sequence (International Human Genome Sequencing Consortium 2001). Eutherian PARs now include only a few genes (e.g., Van Laere et al. 2008), making it unlikely that SA polymorphisms will be found among them, so mammal PARs are no longer likely to be informative abo ...