Multiple Domains Exist within the Upstream Activator
... and sugar derivatives called opines. The inciting strain of Agrobacterium can utilize these opines as a carbon and sometimes a nitrogen source. Agrobacterium strains can be classified based upon their ability to catabolize particular opines. (For recent reviews of the crown gall tumorigenesis proces ...
... and sugar derivatives called opines. The inciting strain of Agrobacterium can utilize these opines as a carbon and sometimes a nitrogen source. Agrobacterium strains can be classified based upon their ability to catabolize particular opines. (For recent reviews of the crown gall tumorigenesis proces ...
Progress and promise in understanding the genetic
... its journal editors) have insisted on two criteria for declaring an association to be genuine. First, the association must meet stringent levels of statistical significance (e.g. p , 5 1028). This has often been justified on the basis of multiple hypothesis testing [6], although others (including ...
... its journal editors) have insisted on two criteria for declaring an association to be genuine. First, the association must meet stringent levels of statistical significance (e.g. p , 5 1028). This has often been justified on the basis of multiple hypothesis testing [6], although others (including ...
- Wiley Online Library
... They comprise endo-1,4-b-D-xylanases (EC 3.2.1.8), which generate xylo-oligosaccharides (Table S4). The degradation of xylooligosaccharides is mediated by b-D-xylosidases, whereas elimination of the side groups is catalysed by a-L-arabinofuranosidases, a-D-glucuronidases, acetylxylanesterases, ferul ...
... They comprise endo-1,4-b-D-xylanases (EC 3.2.1.8), which generate xylo-oligosaccharides (Table S4). The degradation of xylooligosaccharides is mediated by b-D-xylosidases, whereas elimination of the side groups is catalysed by a-L-arabinofuranosidases, a-D-glucuronidases, acetylxylanesterases, ferul ...
- Wiley Online Library
... effective condensing agent among polyphosphates, particularly because it can serve as a phosphorylating reagent in aqueous and strongly alkaline solution (pH 12) (Etaix & Orgel, 1978; Yamagata et al., 1995; Ozawa et al., 2004). The prebiotic synthesis proceeds by the thermolysis of phosphate to yiel ...
... effective condensing agent among polyphosphates, particularly because it can serve as a phosphorylating reagent in aqueous and strongly alkaline solution (pH 12) (Etaix & Orgel, 1978; Yamagata et al., 1995; Ozawa et al., 2004). The prebiotic synthesis proceeds by the thermolysis of phosphate to yiel ...
Recent advances in the molecular genetics of congenital
... Fig. 1 Demonstration of a 13 base-pair deletion (964del13) at nucleotide 964 in the autoimmune regulator gene (AIRE-1) in two UK families with autoimmune polyendocrinopathy type 1 (APS1). (a) shows the wild-type (WT) and the mutant (M) (964del13) DNA sequences. This deletion abolishes the recognitio ...
... Fig. 1 Demonstration of a 13 base-pair deletion (964del13) at nucleotide 964 in the autoimmune regulator gene (AIRE-1) in two UK families with autoimmune polyendocrinopathy type 1 (APS1). (a) shows the wild-type (WT) and the mutant (M) (964del13) DNA sequences. This deletion abolishes the recognitio ...
Multi-petal cyclamen flowers produced by
... In cyclamen, transcripts of CpAG1 were mainly detected in the stamen, and CpAG2 expression was mainly detected in the carpel, although the transcripts of each gene were also detected in stamen, carpel and receptacle6. Chimeric repressor gene-silencing technology (CRES-T) provides a powerful tool for ...
... In cyclamen, transcripts of CpAG1 were mainly detected in the stamen, and CpAG2 expression was mainly detected in the carpel, although the transcripts of each gene were also detected in stamen, carpel and receptacle6. Chimeric repressor gene-silencing technology (CRES-T) provides a powerful tool for ...
More about the. tabby mouse and about the Lyon hypothesis
... Autosomal genes are present in duplicate in the body cells of both sexes. Genes carried in the X-chromosome are present in double dose in the mammalian female, but only in single dose in the mammalian male. Despite this disparity in gene dosage, the phenotypic effects of such genes are generally the ...
... Autosomal genes are present in duplicate in the body cells of both sexes. Genes carried in the X-chromosome are present in double dose in the mammalian female, but only in single dose in the mammalian male. Despite this disparity in gene dosage, the phenotypic effects of such genes are generally the ...
Descriptions of Banbury Conference
... xenopus model for fragile X, and the insights which this may offer in understanding the transport functions of FMRP. The next session focused on the metabotropic glutamate receptors (mGluRs). Ever since the original discovery by Bill Greenough’s group that mGluR activation triggers local synthesis o ...
... xenopus model for fragile X, and the insights which this may offer in understanding the transport functions of FMRP. The next session focused on the metabotropic glutamate receptors (mGluRs). Ever since the original discovery by Bill Greenough’s group that mGluR activation triggers local synthesis o ...
The TP53 Gene, Tobacco Exposure, and Lung Cancer
... quality and reliability of the published work. In addition, some investigators may have published the same data in several publications, and the duplications may not have been clearly identified. These limitations also result in wrongful interpretations. However, if these limitations are understood, ...
... quality and reliability of the published work. In addition, some investigators may have published the same data in several publications, and the duplications may not have been clearly identified. These limitations also result in wrongful interpretations. However, if these limitations are understood, ...
Mendelian Genetics
... – crossed plants with one trait to plants with the alternate trait (P = “parental” generation) – self-pollinated offspring of P (F1 = first filial ...
... – crossed plants with one trait to plants with the alternate trait (P = “parental” generation) – self-pollinated offspring of P (F1 = first filial ...
Technical Targets
... CO. This case study provides evidence that hyp1 and hyp2 genes are complementary—that either copy is able to mature the CBS O2-tolerant hydrogenase. Yet based on the qRTPCR evidence, initial work will focus on co-expressing only hyp1 genes with the CBS hydrogenase in Synechocystis for photolytic H2 ...
... CO. This case study provides evidence that hyp1 and hyp2 genes are complementary—that either copy is able to mature the CBS O2-tolerant hydrogenase. Yet based on the qRTPCR evidence, initial work will focus on co-expressing only hyp1 genes with the CBS hydrogenase in Synechocystis for photolytic H2 ...
Cutting Edge: DNA Polymerases and Are Dispensable for Ig Gene
... excluded its participation in the mutation process (5). Over the past 4 years, nine additional DNA polymerases (if one includes Rev1, a deoxycytidyl transferase) have been identified (reviewed in Ref. 2). Although many of these enzymes have bacterial or yeast homologs with known repair function, the ...
... excluded its participation in the mutation process (5). Over the past 4 years, nine additional DNA polymerases (if one includes Rev1, a deoxycytidyl transferase) have been identified (reviewed in Ref. 2). Although many of these enzymes have bacterial or yeast homologs with known repair function, the ...
No correlation between phenotype and genotype in boys with a
... therefore explain the lack of genotype-phenotype correlation discussed here. Polymorphisms have been shown to modulate the phenotypic expression of disease mutations in other genes, for example, CFTR,22 23 and very little is known about variation in the introns in MECP2 or the importance of the alte ...
... therefore explain the lack of genotype-phenotype correlation discussed here. Polymorphisms have been shown to modulate the phenotypic expression of disease mutations in other genes, for example, CFTR,22 23 and very little is known about variation in the introns in MECP2 or the importance of the alte ...
Journal of Bacteriology
... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...
... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...
MOLECULAR STUDY OF IDIOPATHIC NEPHROTIC SYNDROME
... sí!!!Ah!yporresolvermelasmilesdedudassobreelinglés!Al’Elena,pertotal’ajudaatotselsnivells, perpreocuparͲtesemprepercomestic,pelsbonsconsells,ipersertanoptimistaipositiva,etsunsol.A laBea,perhaverͲmeajudattantesvegadesenmiltemes:científics,devestua ...
... sí!!!Ah!yporresolvermelasmilesdedudassobreelinglés!Al’Elena,pertotal’ajudaatotselsnivells, perpreocuparͲtesemprepercomestic,pelsbonsconsells,ipersertanoptimistaipositiva,etsunsol.A laBea,perhaverͲmeajudattantesvegadesenmiltemes:científics,devestua ...
Shoot Branching and Leaf Dissection in Tomato Are
... of both plant species. Most eudicots originated from an ancient hexaploid progenitor (Van de Peer et al., 2009). During subsequent evolution, the Brassicaceae underwent two rounds of WGD (Simillion et al., 2002), tomato had one WGD (Fawcett et al., 2009) and some species (e. g., grape) had no additi ...
... of both plant species. Most eudicots originated from an ancient hexaploid progenitor (Van de Peer et al., 2009). During subsequent evolution, the Brassicaceae underwent two rounds of WGD (Simillion et al., 2002), tomato had one WGD (Fawcett et al., 2009) and some species (e. g., grape) had no additi ...
Lactic acid bacteria as a cell factory: rerouting of carbon metabolism
... an important role regulation of sugar utilization, both at the level of transcription of genes involved in use of a specific sugar and at the level of sugar transport. This phosphocarrier protein contains two residues that are target for phosphorylation. A histidine residue in the N-terminal part of ...
... an important role regulation of sugar utilization, both at the level of transcription of genes involved in use of a specific sugar and at the level of sugar transport. This phosphocarrier protein contains two residues that are target for phosphorylation. A histidine residue in the N-terminal part of ...
Chapter 4: Individual gene function
... important caveat to using gene products (RNAs or proteins) as evidence that an allele is a null is that a gene could have activity at a low level of product that cannot be easily detected. It is possible that even when we cannot detect a gene product, there may be enough gene product present in the ...
... important caveat to using gene products (RNAs or proteins) as evidence that an allele is a null is that a gene could have activity at a low level of product that cannot be easily detected. It is possible that even when we cannot detect a gene product, there may be enough gene product present in the ...
DNA SEQUENCING (using a Li
... position. The DNA sequencer that we will use (Li-cor model 4200L) requires 4 reactions per DNA sequence, since each reaction is labeled using the same dye. In this case the dye emits in the infrared range (2 dyes are available, one emitting a t 700 nm, and one a t 800 nm). The advantages to this Sys ...
... position. The DNA sequencer that we will use (Li-cor model 4200L) requires 4 reactions per DNA sequence, since each reaction is labeled using the same dye. In this case the dye emits in the infrared range (2 dyes are available, one emitting a t 700 nm, and one a t 800 nm). The advantages to this Sys ...
Case Report Section
... reported t(4;12) AML cases; seven were characterized as AML-M0 and four AML-M1. Previous reports suggest that less than 50% of cases achieve remission with intensive induction chemotherapy. Of the patients who do not achieve morphologic remission, none survived beyond six months (Hamaguchi et al., 1 ...
... reported t(4;12) AML cases; seven were characterized as AML-M0 and four AML-M1. Previous reports suggest that less than 50% of cases achieve remission with intensive induction chemotherapy. Of the patients who do not achieve morphologic remission, none survived beyond six months (Hamaguchi et al., 1 ...
HD13 - Columbia University
... • Etiology poorly understood because of variable expression and incomplete penetrance ...
... • Etiology poorly understood because of variable expression and incomplete penetrance ...
Genome Projector: zoomable genome map with multiple views
... biological context for the visualisation and interpretation of data, and serve as a gateway to information stored in a database [2]. For example, the popular two-dimensional genome map viewer, Gbrowse, provides an entry point for browsing the model organism genome database, GMOD [3], and biochemical ...
... biological context for the visualisation and interpretation of data, and serve as a gateway to information stored in a database [2]. For example, the popular two-dimensional genome map viewer, Gbrowse, provides an entry point for browsing the model organism genome database, GMOD [3], and biochemical ...
Fish-on-a-chip: a sensitive detection microfluidic system for
... Recently, Ivan and colleagues reported that human brain diseases such as AD, which are present in the human brain and are associated with chromosomal disorders [40-42]. In this research, chromosome 21 aneuploidy in lymphocytes and fibroblasts cells of AD patients was observed using FISH techniques [ ...
... Recently, Ivan and colleagues reported that human brain diseases such as AD, which are present in the human brain and are associated with chromosomal disorders [40-42]. In this research, chromosome 21 aneuploidy in lymphocytes and fibroblasts cells of AD patients was observed using FISH techniques [ ...
Comparison of Target-Capture and Restriction
... explored. Here, we utilize RAD-seq and UCE data to infer a phylogeny of the bird genus Piranga. The group has a range of divergence dates (0.5–6 myr), contains 11 recognized species, and lacks a resolved phylogeny. We compared two species tree methods for the RAD-seq data and six species tree method ...
... explored. Here, we utilize RAD-seq and UCE data to infer a phylogeny of the bird genus Piranga. The group has a range of divergence dates (0.5–6 myr), contains 11 recognized species, and lacks a resolved phylogeny. We compared two species tree methods for the RAD-seq data and six species tree method ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.