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Gen660_Lecture9B_GeneExpressionEvo_2014
Gen660_Lecture9B_GeneExpressionEvo_2014

... These cases can be distinguished by measuring the: Mutational variance (Vm) = how much expression of a given gene varies in response to mutation but in the ABSENCE of selection? Genetic variance (Vg) = how much expression of a given gene varies in natural populations (i.e. influenced by mutation + s ...
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Document

... 5) cDNA is made from mRNA by the enzyme______________________ 6a) Double stranded cDNA for a protein coding gene usually has what three identifiable regions: ___________ ___________ _____________ 6b) Must these three regions equate to three exons? (yes, no –circle one) 7) The triplet code for transl ...
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Ch 18.2-18.5 PPT

...  Tightly bound DNA less accessible for transcription  DNA methylation: methyl groups added to DNA; tightly packed;  transcription  Histone acetylation: acetyl groups added to histones; loosened;  transcription ...
Homework 1 (9/16/15)
Homework 1 (9/16/15)

... • Imputation of time series medical data using Gaussian process regression • Exploratory data analysis of tumor images and gene expression data jointly using canonical correlation analysis • Inferring latent structure in genotype data using biclustering • Quantifying cell type heterogeneity in devel ...
KURSA CEĻVEDIS
KURSA CEĻVEDIS

... 1. Regulation of eukaryotic genes Reminder of DNA replication, recombination, and repair mechanisms. Gene expression and the various effects of mutations (exercises). General transcription factors, gene regulatory proteins. Promoters, enhancers, silencers, insulators, and locus control regions. Gene ...
Schol Biol: Genetics
Schol Biol: Genetics

... Genes within DNA are a code for proteins (proteins do the actual work in our bodies) In cells, genes are copied into a message form (messenger RNA/mRNA) to then be used by the protein making factories (ribosomes) The copying for any particular gene is switched on and off as required Specific target ...
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Transcription and Translation

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... • Identifying (annotating) human genes, i.e. finding what they are and what they do, is a difficult problem. It is considerably harder than the early success story for ßglobin might suggest (see Lesk’s “Introduction to bioinf”). • The human factor VIII gene (whose mutations cause hemophilia A) is sp ...
Supplemental Methods
Supplemental Methods

... that were significantly perturbed in the differentially expressed gene (DEG) dataset. The DEGs were mapped to genetic networks in the database and ranked by score. The significance of the molecular and cellular functions over-represented in the gene set, as well as the signaling pathways and biologi ...
Cracking the code of life
Cracking the code of life

... 10. Would you be willing to take a test to tell you if your children would be at risk for certain disorders and diseases? Why or why not? ...
Chapter 18 - Regulation of Gene Expression - Bio-Guru
Chapter 18 - Regulation of Gene Expression - Bio-Guru

... factors and other proteins are localized in specific cytoplasmic regions of the unfertilized egg or zygote • These molecules affect cell fate decisions by segregating into different embryonic cells and controlling distinct gene activities in these cells (specialized transcription factors will only t ...
APBio-StudyGuide-Ch18
APBio-StudyGuide-Ch18

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Central Dogma.pptx

... Store and maintain the integrity of the information from cell to cell or parent to offspring. Takes place pre-mitosis and meiosis. Uses original (parent strand) as a template to create to new daughter strands (semi-conservative replication). ...
OCR Biology B - Centre of the Cell
OCR Biology B - Centre of the Cell

... 3.1.2 The developing individual: meiosis, growth and development 5.1.1 Patterns of inheritance 5.1.2 Population genetics and epigenetics 2.1.4 Nucleic acids (a) the structure of a nucleotide as the monomer from which nucleic acids are made (c) (i) the structure of the DNA molecule, including a revie ...
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Slide 1

... referring to the subcellular structures that stained by some dyes. ...
DNA Know your Molecules
DNA Know your Molecules

... binds to “turn off” ...
DNA Technology
DNA Technology

... So what does all this mean? • We can already economically sequence a human genome. • These technologies present a huge variety of opportunities and dangers. • Your generation must be aware of these technologies as you will make the ultimate decisions about how these technologies are used. ...
Biology Vocabulary 8, test on Thursday, 1/19/17
Biology Vocabulary 8, test on Thursday, 1/19/17

... selective breeding of closely related organisms to produce desired traits and eliminate undesired traits, resulting in pure lines; however, harmful recessive traits can also be passed on complex inheritance pattern in which the heterozygous phenotype is intermediate between those of the two homozygo ...
L3.2ReducingYourRisk - jj-sct
L3.2ReducingYourRisk - jj-sct

... age, and may indicate the presence of a gene mutation that increases the risk of cancer. They may also be a sign of shared environmental or lifestyle factors. Genetic Marker Alteration in DNA that may indicate an increased risk of developing a specific disease or disorder Hereditary Cancer An inheri ...
2-3 DNA to Proteins - Lighthouse Christian Academy
2-3 DNA to Proteins - Lighthouse Christian Academy

... is similar to DNA except it is only one strand. o RNA to Ribosome – The RNA then leaves the nucleus and attaches to a ribosome which “reads” the code on the RNA. o Ribosome builds the Protein – As the RNA reads the code it attaches the amino acids in the order listed. This builds the protein. o ...
Test: Gene Regulation Free Response Questions It is known that
Test: Gene Regulation Free Response Questions It is known that

... The p53 protein can activate genes that halt the cell cycle by binding to CDKs The proteins could signal pathways that inhibit or halt the cell cycle by binding to miRNAs v. The proteins can activate suicide genes – leading the cell to apoptosis 4. Bacteria often respond to environmental change by r ...
Video Homework Assignment “Cell Biology & Cancer”
Video Homework Assignment “Cell Biology & Cancer”

... function (unable to produce what they are supposed to produce) • All they do is make more cancer cells • Will induce blood vessels to grow (angiogenesis) • Has the ability to spread (metastasize) • Cells will divide and grow into tumors – Benign (non-cancerous) vs. -Malignant (cancerous) ...
How are protein made in our cells?
How are protein made in our cells?

... • What are 3 differences between DNA and RNA? What are 3 types of RNA? • What is transcription? What are the steps in this process? • What is translation? What are the steps in this process? • Protein is made up of smaller building blocks called ______ ______. • What is the mRNA sequence for the fol ...
Fine Structure and Analysis of Eukaryotic Genes
Fine Structure and Analysis of Eukaryotic Genes

... • The mRNA-coding portion of a gene can be split by DNA sequences that do not encode mature mRNA • Exons code for mRNA, introns are segments of genes that do not encode mRNA. • Introns are found in most genes in ...
Document
Document

... the nucleus -tRNA contains an anticodon that is antiparallel to the codons ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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