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Weighted gene co-expression network analysis (WGCNA) and
Weighted gene co-expression network analysis (WGCNA) and

... reporting a list of individual parts • Focus on gene clusters: “modules” rather than individual genes ...
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AP Biology Summer Assignment Chapter 3 Quiz 2016-17
AP Biology Summer Assignment Chapter 3 Quiz 2016-17

... the only remaining stable aspect of the protein’s structure is its primary structure. b. If the van der Waals forces in a protein are disturbed, only the quaternary structure will be affected. c. Tertiary and quaternary structures of a protein are stabilized by different types of interactions. d. A ...
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Selected Topics in Rehabilitation and Radiology

... Rehabilitation and Radiology OBJECTIVES Demystify/explain fancy new neuroimaging techniques at a basic level  Get a few more board questions right  Choose well from available options, and know when to consult your radiologist  Recognize and respect contraindications  Recognize limitations and a ...
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... They include thousands of different substances which can be classified into five basic types: structural, regulatory, immunological, transport and catalytic. In this activity, you will focus on the action or catalytic proteins; these proteins, called enzymes, act as catalysts to facilitate chemical ...
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... naturally, the process is unaided. • Example: –Decomposition of dead matter = spontaneous endothermic reactions. (absorbs heat energy) –Forest fire = spontaneous exothermic reactions. (releases heat energy) ...
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... High throughput technologies inevitably produce vast quantities of data. This presents challenges in terms of developing effective analysis methods, particularly where the analysis involves combining data derived from different experimental technologies. In this investigation, we applied a systemati ...
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Metabolism: the Degradation and Synthesis of Living Cells

... become part of our body and allow growth to occur (what is the fate of the sugar, fat, protein and nucleic acids that enter our body along with the food ?) • Why do we become fat by only eating sugar? • What is the molecular nature of the large number of genetic diseases? How can we find ways to pre ...
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... Recently, there’s been a special medical (pill) formula discovered for PKU patients called Kuvan. It’s possible to have a wide range of PKU, from mild to severe, but it’s suggested to stick to a diet regiment for life. ...
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ALLELE Alternative form of a gene. CHROMOSOMES DOMINANT
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Metabolic network modelling



Metabolic network reconstruction and simulation allows for an in-depth insight into the molecular mechanisms of a particular organism. In particular, these models correlate the genome with molecular physiology. A reconstruction breaks down metabolic pathways (such as glycolysis and the Citric acid cycle) into their respective reactions and enzymes, and analyzes them within the perspective of the entire network. In simplified terms, a reconstruction collects all of the relevant metabolic information of an organism and compiles it in a mathematical model. Validation and analysis of reconstructions can allow identification of key features of metabolism such as growth yield, resource distribution, network robustness, and gene essentiality. This knowledge can then be applied to create novel biotechnology.In general, the process to build a reconstruction is as follows: Draft a reconstruction Refine the model Convert model into a mathematical/computational representation Evaluate and debug model through experimentation↑
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