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B cells
B cells

... within tissue, have a role in innate and adaptive immunity • They engulf pathogens and debris via phagocytosis, and move around via amoeboid movement ...
B-LYMPHOCYTES
B-LYMPHOCYTES

... The body must be able to recognize the difference between “self” and “nonself.” (Any lymphocytes with antibodies that recognize one’s own body tissue as an antigen ar ekilled during fetal life.) ...
Quiz 2 Practice with Answers
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... a. alpha (α) and beta (β); CD4+ b. alpha (α) and beta2-microglobulin; CD4+ c. alpha (α) and beta (β); CD8+ d. alpha (α) and beta2-microglobulin ; CD8+ e. alpha (α) and beta2-microglobulin; gamma-delta 7. What is the timing of transcription factor gene activation after TcR-mediated T cell activation? ...
Immune Responses to Extracellular Bacteria Infection by
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...  A significant proportion of gd T cells has been observed in the initial phase. These gd T cells apparently play an important role in the organization of a tight and wellstructured granulomatous lesion.  Granulomas are at the forefront of protection by restricting bacterial replication at, as well ...
Lecture 4: Host Response to Infection
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Lymphoid System I: Peripheral System, Lymph Node
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Supplementary Materials and Methods
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... 3. Grafts between identical twins are called _______________. 4. The process whereby leukocytes pass through the wall of a capillary is called ___________. 5. Lymphocytes that develop immunocompetence in the _________ are T cells. 6. The inflammatory response is considered the body’s ___________ lin ...
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Specific Resistance = Immunity
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McDermott
McDermott

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The specific immune response B and T cells

... 5. clonal expansion / clonal proliferation / T cells divide by mitosis; 6. R ‘T cells clone’ unqualified / ‘reproduction’ / ‘replication’ 7. T helper cells release, cytokines / lymphokines; 8. stimulate B cells to, divide / clone / differentiate (into plasma cells); 9. stimulate macrophages to carry ...
Physiology for Pharmacy Students Tortora 13th Ebaa M Alzayadneh
Physiology for Pharmacy Students Tortora 13th Ebaa M Alzayadneh

... – Leukocytosis is a normal protective response to invaders, strenuous exercise, anesthesia and surgery – Leukopenia is never beneficial – General function to combat invaders by phagocytosis or immune responses University of Jordan ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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