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The Lymphatic System 2011
The Lymphatic System 2011

... Antibody – protein that B cells produce in response to the presence of a non-self antigen. When an antibody combines with an antigen, it renders the antigen-bearing cell/particle inactive and leads to the destruction of the cell. Causes agglutination or massing of cells together so they can be destr ...
2 cells
2 cells

... are constitutively present in tissues and recognize rapidly microbes that enter these tissues. Initiate the immune response. •They have phagocytic capabilities migrate to lymph nodes, and display microbial antigens to T lymphocytes,professional antigen presentimg cells (APC) Neutrophil granulocytes ...
SBI 3CW - TeacherWeb
SBI 3CW - TeacherWeb

... 2. Viruses do not contain DNA or RNA. 3. Viruses do not contain a cell membrane, nucleus, or cytoplasm. 4. Viruses are destroyed by antibiotics. 5. The genetic material from viruses can direct the host cell to produce new viruses. Multiple Choice 6. Injecting a person with plasma antibodies from a p ...
Immune System
Immune System

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... Many blood group antibodies that are capable of agglutinating antigen positive RBCs suspended in saline in tests performed at 22 C are IgM causing visible agglutination, ie, ABO antibodies. ...
The Immune System
The Immune System

... filtered out. The spleen also helps store white blood cells that are used for destroying harmful bacteria in the body. The spleen can be removed and have the body continue to function. However, one’s ability to fight infections will be slightly reduced if the spleen is not present. ...
adaptive response
adaptive response

B. Structure
B. Structure

PPT 2003
PPT 2003

... killer T cells on infected cells, not on viruses and other pathogens that are outside our cells in blood and tissues • It would be extremely dangerous to have unpresented antigen signal T cell killing. • Most proteins made in a pathogen-infected cell remain inside the cell, and never make their way ...
antigen presentation clonal selection induction of antibody synthesis
antigen presentation clonal selection induction of antibody synthesis

... interleukin 2 which stimulates the B cell to divide and differentiate into antibody-secreting plasma cells. Many undifferentiated B cells remain in the lymphoid tissue as Memory Cells. This process is termed CLONAL SELECTION and results in IMMUNOLOGICAL MEMORY. Upon a subsequent exposure, antigen pr ...
Myeloid cells in ocular health and disease
Myeloid cells in ocular health and disease

... Presentation Description: Immune suppressive cells of myeloid origin accumulate in individuals with a variety of conditions. These conditions typically involve inflammation, and range from an inflammatory tumor microenvironment to infection, stress, and aging. The predominant cell types are myeloid- ...
The Immune Response - hrsbstaff.ednet.ns.ca
The Immune Response - hrsbstaff.ednet.ns.ca

... The Third Line of Defense (cont’d)  All cells have special markers located on their cell membranes, which are known as antigens (antibody generator). ...
The Immune Response - hrsbstaff.ednet.ns.ca
The Immune Response - hrsbstaff.ednet.ns.ca

... The Third Line of Defense (cont’d)  All cells have special markers located on their cell membranes, which are known as antigens (antibody generator). ...
Cytokines
Cytokines

plant tissues: vascular system
plant tissues: vascular system

... The Vascular System: For plants to survive, they must…  take in nutrients & water from environment  transport water up to the leaves, and glucose back down for storage The plant’s vascular system is their “circulatory system” designed to transport materials with the plant! ...
Editorial: Bacterial Exotoxins: How Bacteria Fight the Immune System
Editorial: Bacterial Exotoxins: How Bacteria Fight the Immune System

... pathways, resulting in adjustment of the host immune response to infection and modification of inflammatory responses both locally and systemically (1, 2). Exotoxins can be single polypeptides or heteromeric protein complexes that act on different parts of the cells. At the cell surface, they may in ...
Igs and the Immune System
Igs and the Immune System

... T-cells are involved in what are known as ‘cell mediated responses’. They respond to cells which have foreign bodies displayed on their surface and can eliminate virus-infected and cancerous cells. T-cells can also respond to chemical signals to activate and search for invading bacteria. The B-cells ...
activate B cells
activate B cells

... 2) Role of Th cells in humoral immune response to TD-Ag  For a protein Ag to stimulate Ab response, B cells and Th cells specific for that Ag must come together in lymphoid organs and interact in a way that stimulates B cell proliferation and differentiation. ...
432W9EX1
432W9EX1

... a) secreted form is a pentamer of the basic H2L2 unit b) binds to Fc receptors on mast cells c) multimeric forms have J chain d) present on the surface of mature, unprimed B cells e) the most abundant isotype in serum f) major antibody in secretions such as saliva, tears, and breast milk g) present ...
The Generation of Diversity (GOD): How to Ensure
The Generation of Diversity (GOD): How to Ensure

... self tolerance and induction of an immune response against components of the self. • Activation of the immune system often leads to tissue damage; disease results. • Disease may be organ specific or generalized. • Evidence for genetic predisposition. ...
Microbial Infection
Microbial Infection

Practice human body test
Practice human body test

... A marathon runner frequently experiences muscle cramps while running. If he stops running and rests, the cramps eventually go away. The cramping in the muscles most likely results from 1.  lack of adequate oxygen supply to the muscle 2.  the runner running too slowly 3.  the runner warming up before ...
59 immunology structure and function of immune system
59 immunology structure and function of immune system

... T and B cells use antigen-specific receptors to recognize and destroy antigens. To recognize antigen, part of the antigen must be presented to T-cells by an antigen presenting cell (APC), such as macrophages and dendritic cells. After engulfing and processing the antigen, the APC displays specific p ...
The Immune System - The JAMA Network
The Immune System - The JAMA Network

... • The adaptive immune response is slower than the innate response but is better able to target specific pathogens. There are 2 main cell types involved in this response: T cells and B cells. Some T cells kill pathogens and infected cells. Other T cells help control the adaptive immune response. The ...
DISEASE - IMMUNE SYSTEM
DISEASE - IMMUNE SYSTEM

... to distinguish between its own substances (itself) and foreign substances (non-self). • Any foreign substance that triggers a specific defense response is called an antigen. ...
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Phagocyte



Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.
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