Circulating Organ-Specific MicroRNAs Serve as Biomarkers
... with some limitation of diagnostic accuracy [3,4]. Biochemical and immunological assays are either of low sensitivity or low specificity [5,6]. For example, biochemical biomarkers of serum creatinine and urine albumin are classical indicators of kidney injury following renal allo (xeno)-transplantat ...
... with some limitation of diagnostic accuracy [3,4]. Biochemical and immunological assays are either of low sensitivity or low specificity [5,6]. For example, biochemical biomarkers of serum creatinine and urine albumin are classical indicators of kidney injury following renal allo (xeno)-transplantat ...
The Role of Nitric Oxide in Host Defence Against Mycobacterium
... Considering aggravating factors, such as HIV co-infection and emerging drug resistance, new therapeutic interventions are urgently needed. Following exposure to M. tuberculosis, surprisingly few individuals will actually develop active disease, indicating effective defence mechanisms. One such candi ...
... Considering aggravating factors, such as HIV co-infection and emerging drug resistance, new therapeutic interventions are urgently needed. Following exposure to M. tuberculosis, surprisingly few individuals will actually develop active disease, indicating effective defence mechanisms. One such candi ...
Outlines
... A remarkable feature of the host defense apparatus is its ability to produce highly reactive oxidizing reagents, including oxidizing radicals and singlet oxygen. The importance of this so called “respiratory burst (RB)” became obvious when the syndrome chronic granulomatous disease (CGD), characteri ...
... A remarkable feature of the host defense apparatus is its ability to produce highly reactive oxidizing reagents, including oxidizing radicals and singlet oxygen. The importance of this so called “respiratory burst (RB)” became obvious when the syndrome chronic granulomatous disease (CGD), characteri ...
Biological Inventions
... extent that can be expected from a person skilled in the art who is supposed to have ordinary skill, the detailed description of the invention is not described in such a manner that enables a person skilled in the art to carry out the invention. (1) Invention of a Product For an invention of a produ ...
... extent that can be expected from a person skilled in the art who is supposed to have ordinary skill, the detailed description of the invention is not described in such a manner that enables a person skilled in the art to carry out the invention. (1) Invention of a Product For an invention of a produ ...
Biological Inventions
... (vi) Deposit of microorganisms, etc. (For information on the deposit and furnishing of microorganisms, see "5.1 Deposit and Furnishing of Microorganisms") (a) For an invention of a gene, a vector, a recombinant vector, a transformant, a fused cell, a recombinant protein, a monoclonal antibody, etc. ...
... (vi) Deposit of microorganisms, etc. (For information on the deposit and furnishing of microorganisms, see "5.1 Deposit and Furnishing of Microorganisms") (a) For an invention of a gene, a vector, a recombinant vector, a transformant, a fused cell, a recombinant protein, a monoclonal antibody, etc. ...
The Characteristics of the Cell-Mediated Immune Response Identify
... Mediterranean area and recent studies tend to exclude that HBV genetic mutations are responsible for the strong suppression of viral replication typical of occult HBV infection.8 Several other mechanisms could be involved, such as viral interference by other viruses, including hepatitis C virus (HCV ...
... Mediterranean area and recent studies tend to exclude that HBV genetic mutations are responsible for the strong suppression of viral replication typical of occult HBV infection.8 Several other mechanisms could be involved, such as viral interference by other viruses, including hepatitis C virus (HCV ...
maitake mushroom
... with deleterious side effects, in tumor-bearing mice. They demonstrated that by enhancing the T helper (Th)1-dominant response, D-fraction decreases the amount of MMC required to manage cancer. Although further studies are required to clarify whether combined therapy using D-fraction is effective, t ...
... with deleterious side effects, in tumor-bearing mice. They demonstrated that by enhancing the T helper (Th)1-dominant response, D-fraction decreases the amount of MMC required to manage cancer. Although further studies are required to clarify whether combined therapy using D-fraction is effective, t ...
Kokatla_Wiley_2014
... Recognizing limitations inherent in docking methods,[17] and cognizant of the crystallographically determined observation of large structural excursions (15 Å) of the top lateral face of TLR8 upon ligand binding,[16] we sought to directly verify and validate our docking results. We were delighted to ...
... Recognizing limitations inherent in docking methods,[17] and cognizant of the crystallographically determined observation of large structural excursions (15 Å) of the top lateral face of TLR8 upon ligand binding,[16] we sought to directly verify and validate our docking results. We were delighted to ...
Materials and methods
... et al., 2006). While ABA is largely responsible for abiotic stress induced stomatal closure, oxylipin ...
... et al., 2006). While ABA is largely responsible for abiotic stress induced stomatal closure, oxylipin ...
EndoS and SpeB from Streptococcus pyogenes
... to analyze each sample. After the wells were washed with PBS, all of the wells were blocked for 2 h at room temperature with Veronal-buffered saline containing Ca2⫹ (0.15 mmol/liter), Mg2⫹ (0.5 mmol/liter), and 0.1% gelatin. Purified complement proteins were added to the MBL-deficient serum from whi ...
... to analyze each sample. After the wells were washed with PBS, all of the wells were blocked for 2 h at room temperature with Veronal-buffered saline containing Ca2⫹ (0.15 mmol/liter), Mg2⫹ (0.5 mmol/liter), and 0.1% gelatin. Purified complement proteins were added to the MBL-deficient serum from whi ...
Mechanisms underlying stress-induced hyperglycemia in critically ill
... that intensive insulin therapy reduces the rate of bacteremia and wound infection in burn patients [14,15]. Control of blood glucose decreased the rate of deep sternal wound infection in diabetic patients following open heart surgery [16]. The rate of worse outcome in nondiabetic patients with acute ...
... that intensive insulin therapy reduces the rate of bacteremia and wound infection in burn patients [14,15]. Control of blood glucose decreased the rate of deep sternal wound infection in diabetic patients following open heart surgery [16]. The rate of worse outcome in nondiabetic patients with acute ...
Update on allergy immunotherapy - Journal of Allergy and Clinical
... Various terms have been used to describe immunotherapy for treating allergy. Examples are allergen-specific immunotherapy, specific immunotherapy, allergen immunotherapy, and allergy immunotherapy (AIT). Because there is a need for uniformity in naming, and because immunotherapy can include both all ...
... Various terms have been used to describe immunotherapy for treating allergy. Examples are allergen-specific immunotherapy, specific immunotherapy, allergen immunotherapy, and allergy immunotherapy (AIT). Because there is a need for uniformity in naming, and because immunotherapy can include both all ...
13 20 s si
... Dendritic cells (DC) are the most potent antigen-presenting cells in the immune system, linking innate and adaptive immune responses. However, it has been suggested a dual role of DC in Human Immunodeficiency Virus type 1 (HIV-1) infection by increasing the spread of HIV-1 while trying to trigger an ...
... Dendritic cells (DC) are the most potent antigen-presenting cells in the immune system, linking innate and adaptive immune responses. However, it has been suggested a dual role of DC in Human Immunodeficiency Virus type 1 (HIV-1) infection by increasing the spread of HIV-1 while trying to trigger an ...
Anaphylaxis_01 (Pathophysiology)
... The binding of histamine to H1 receptors initiates phospholipase C-dependent calcium mobilization, converting L-arginine to NO through activity of NOS. Various isoforms of NOS have been identified, depending on tissue in which they were first isolated. Constitutively expressed isoforms, ie, eNOS and ...
... The binding of histamine to H1 receptors initiates phospholipase C-dependent calcium mobilization, converting L-arginine to NO through activity of NOS. Various isoforms of NOS have been identified, depending on tissue in which they were first isolated. Constitutively expressed isoforms, ie, eNOS and ...
The physiology of blood platelets and changes of their biological
... Boilard et al. 2015, Varon et al. 2015), and are potential mediators of blood coagulation by serving as circulating sources of tissue factor (TF) that is a transmembrane protein involved in thrombin generation. On the surface of MPs some quantity of phospatidylserine – a negatively charged aminophos ...
... Boilard et al. 2015, Varon et al. 2015), and are potential mediators of blood coagulation by serving as circulating sources of tissue factor (TF) that is a transmembrane protein involved in thrombin generation. On the surface of MPs some quantity of phospatidylserine – a negatively charged aminophos ...
Exhibit N. a general information booklet on vaccine safety for parents titled VACCINE SAFETY AND YOUR CHILD, Separating Fact from Fiction , an excerpt from the book Vaccines and Your Child. (PDF: 2.20MB/34 pages)
... example, the influenza and hepatitis B vaccines given to children contain lower quantities of vaccine than those given to adults. Sometimes the opposite is true. For example, the amount of diphtheria and pertussis vaccine contained in the DTaP vaccine given to children is actually more than is in th ...
... example, the influenza and hepatitis B vaccines given to children contain lower quantities of vaccine than those given to adults. Sometimes the opposite is true. For example, the amount of diphtheria and pertussis vaccine contained in the DTaP vaccine given to children is actually more than is in th ...
Linköping University Post Print Induction of apoptosis in human neutrophils by
... majority of the ROS was extracellular (data not shown). As shown in Fig. 6B, the respiratory burst induced by Mtb was weaker (<15%) than that elicited by an E. coli strain (FimH+, expressing type 1 fimbriae), previously reported to cause strictly ROS-dependent apoptosis [12]. On the other hand, the ...
... majority of the ROS was extracellular (data not shown). As shown in Fig. 6B, the respiratory burst induced by Mtb was weaker (<15%) than that elicited by an E. coli strain (FimH+, expressing type 1 fimbriae), previously reported to cause strictly ROS-dependent apoptosis [12]. On the other hand, the ...
Elevated HMGB1-related interleukin
... Notably, extracellular HMGB1 also functions as an immune adjuvant to trigger a robust response of T cells, dendritic cells, and endothelial cells [3, 14-18]. It is well established that HMGB1 as a pro-inflammatory cytokine in many inflammatory diseases [3]. Extracellular or blood HMGB1 levels were f ...
... Notably, extracellular HMGB1 also functions as an immune adjuvant to trigger a robust response of T cells, dendritic cells, and endothelial cells [3, 14-18]. It is well established that HMGB1 as a pro-inflammatory cytokine in many inflammatory diseases [3]. Extracellular or blood HMGB1 levels were f ...
Interleukin-17A Increases Neurite Outgrowth from Adult
... arthritis have demonstrated similar effects on the SNS (Lorton et al., 2009; Straub et al., 2011). Anatomical remodeling of the SNS often leads to important functional alterations in the system involved. In models of myocardial infarction, the sympathetic outflow to the heart is increased as a resul ...
... arthritis have demonstrated similar effects on the SNS (Lorton et al., 2009; Straub et al., 2011). Anatomical remodeling of the SNS often leads to important functional alterations in the system involved. In models of myocardial infarction, the sympathetic outflow to the heart is increased as a resul ...
Autoantibodies against Muscarinic Acetylcholine Receptor on
... lacrimal glands M3mAChR, which trigger parasympathetic-receptormediated biological effects [25,39,49,50]. We have demonstrated that they are able to recognize a synthetic peptide corresponding in amino acid sequence to the second extracellular loop of the human M3mAChR. The distribution of the amino ...
... lacrimal glands M3mAChR, which trigger parasympathetic-receptormediated biological effects [25,39,49,50]. We have demonstrated that they are able to recognize a synthetic peptide corresponding in amino acid sequence to the second extracellular loop of the human M3mAChR. The distribution of the amino ...
Wang Concepts of Organizational Immunity
... organization has a potential to deal with all types of non-selves, and to maintain their health through learning. Therefore, the function of acquired immunity to" recognize defense - remember" has the features of pertinence, diversity, optimization and of from passive to active. The acquired immunit ...
... organization has a potential to deal with all types of non-selves, and to maintain their health through learning. Therefore, the function of acquired immunity to" recognize defense - remember" has the features of pertinence, diversity, optimization and of from passive to active. The acquired immunit ...
HLA-G - DTU CBS
... abortion compared to induced abortion – Decreased CD4+CD25+ Tregs in spontaneous abortion might induce maternal lymphocyte activation to the semi-allogenic fetus (Sasaki et al 2004) ...
... abortion compared to induced abortion – Decreased CD4+CD25+ Tregs in spontaneous abortion might induce maternal lymphocyte activation to the semi-allogenic fetus (Sasaki et al 2004) ...
Twelfth International Symposium July 2006 program [PDF 748.15KB]
... Welcome to Boston/Cambridge and the 12th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases! After enjoying the splendors of Australia and the warm hospitality in the heart of Bavaria, we are proud to host the EBV Association in the hub of ...
... Welcome to Boston/Cambridge and the 12th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Diseases! After enjoying the splendors of Australia and the warm hospitality in the heart of Bavaria, we are proud to host the EBV Association in the hub of ...