• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Pathophysiology of Lymphomas - Ipswich-Year2-Med-PBL-Gp-2
Pathophysiology of Lymphomas - Ipswich-Year2-Med-PBL-Gp-2

...  Aetiology: Germinal centre B cells, t(14:18) [BCL2]  Pathophysiolology: BCL2 antagonises apoptosis and promotes survival. Calls in reactive cells. Marrow, spleen and liver involvement common. Goes where B cells go (white pulp) ...
Human and Mouse Naïve/Memory T-Cell Panels
Human and Mouse Naïve/Memory T-Cell Panels

Slide 1
Slide 1

... -get an accumulation of immune cells that cannot function or replicate normally, but are more resistant to apoptosis • AIDS is much more severe immune senescence than what is seen in normal aging ...
PDF - The Scripps Research Institute
PDF - The Scripps Research Institute

Study Guide 12 - Adaptive Immunity Chpt. 16
Study Guide 12 - Adaptive Immunity Chpt. 16

... i. exogenous proteins (i.e. those that have been taken up by the cell) are presented  ii. found on antigen presenting cells (macrophages, B cells and dendritic cells)  c. Multiple types – TH1, TH2, and others (don’t need to know these)   d. B cell activation (B cell as the Antigen Presenting Cell (A ...
Laudatio for Adrian Liston
Laudatio for Adrian Liston

... randomly combined during lymphocyte development. This recombination creates a molecular complexity exceeding the number of genes in the genome by several orders of magnitude. Thus, many million of lymphocytes are generated, each of which having a specific receptor and thus being specific for a diffe ...
Defense Against Disease What causes disease? Mechanisms of
Defense Against Disease What causes disease? Mechanisms of

... – He inoculated an 8 year old boy with bacteria possessing the cowpox virus. – Months later, he inoculated the boy with the smallpox virus and he survived the infection. – Soon people all over Europe were being vaccinated against smallpox using the cowpox virus. ...
Logic of the Immune System - Cancer Immunology Research
Logic of the Immune System - Cancer Immunology Research

... immediate response to the invader. Receptors responsible for making these necessary early decisions recognize rather broad macromolecular patterns that distinguish a pathogen from its host. These receptors may function at the cell surface, or may work inside the cell. Stressed or even cancerous cell ...
T cells
T cells

... – over-reaction to environmental antigens • allergens = proteins on pollen, dust mites, in animal saliva • stimulates release of histamine ...
THE IMMUNE SYSTEM
THE IMMUNE SYSTEM

Poster
Poster

... destruction, leading to clotting disorder. Interestingly, mother responders are characterized by the expression of class II HLA DRB3*0101 (also known as DRw52a with other nomenclature) on the surface of Antigen Presenting Cells. Class II HLA molecules play an important role in the initiation of the ...
Types of Immunity
Types of Immunity

... T-Lymphocytes: The T lymphocytes develop from the bone marrow stem cell, travel to the thymus, and mature, (are processed), (T = Thymus), and subsequently reside in the lymphoid nodules that they share with B-lymphocyte precursors. They produce lymphokines. These T cells develop a memory for a singl ...
Memory B Cells and Antibody Function
Memory B Cells and Antibody Function

... Some become plasma cells (immunoglobulin and specific antibodies), and others become memory B cells that recognize the same foreign substances that started the reaction to begin with. These memory B cells have been the subject of intense research in recent years. Clinical Implications of Memory B Ce ...
L1.1.MysteryDisease
L1.1.MysteryDisease

... Medical Interventions Lesson 1.1 The Mystery Infection – Key Terms – Page 1 ...
The Human Immune System
The Human Immune System

... What specific steps would you take to determine the exact cause of the disease? ...
Biol260exam2summer2012
Biol260exam2summer2012

... 18. Infection caused by the gram-negative bacteria Yersinia pestis is a. highly infectious and can be passed from person to person via direct or droplet contact b. maintained in an exanthropic cycle in the United States, where it is endemic in prairie dog populations c. potentially transmitted by f ...
To study humoral and cellular immune response
To study humoral and cellular immune response

...  Adoptive transfer of JEV-immune T cells protected mice from subsequent virus challenge (Mathur et al., 1983; Murali-Krishna et al., 1996). Tcell influencing Antibody  CD4+T helper cell ,played an essential part in the maintenance of an effective antibody response necessary to combat the infection ...
SEPARATED BLOOD Plasma Platelets and white blood cells Red
SEPARATED BLOOD Plasma Platelets and white blood cells Red

... irritation of the plantar fascia - a band of tissue that extends from the heel bone (calcaneus) to the ball of the foot - with an injection of the patient’s own blood platelets. The concentrated platelets promote natural healing and reduction of inflammation. Collecting the Platelets The PRP process ...
File - Pomp
File - Pomp

... isotonic environment between RBC and blood fluids. If concentration is too high, crenation would result, if concentration is too low, cell lysis would result. ...
Document
Document

... a. Main function is the generation of T and B cells b. Bone marrow: hematopoiesis occurs in bone marrow as well as where B cell maturation occurs. Committing to the B cell pathway occurs by rearranging the genes that encode the heavy and light chains of Ag receptor. c. Thymus: precursors to T cell m ...
Anatomy and Physiology TEST 2 – Spring 2015 1. Diagram and
Anatomy and Physiology TEST 2 – Spring 2015 1. Diagram and

... Diagram and label the flow of blood into, through, and out of the heart on the back of the LAST page. Include in your diagram: the right and left atria, the right and left ventricles, the aorta, the aortic semilunar valve, the pulmonary veins, pulmonary arteries, pulmonary trunk, pulmonary semilunar ...
Microsoft Word Version
Microsoft Word Version

... Antibodies help to defend us against infection. Bacteria, viruses and other germs have proteins on their surface, called antigens. The immune system recognizes antigens to be foreign. So, when we have certain infections, B lymphocytes make lots of antibodies which attach to the infecting germs. This ...
immune response lecture3
immune response lecture3

... infection with Plasmodia. Duffy antigen Absence of Duffy antigen: Duffy antigen present on RBCs acts as a receptor for Plasmodium vivax. Its absence limits infection with this parasite. Haemoglobin S: its presence in RBCs provides immunity against Plasmodium falciparum because the parasite cannot fe ...
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034

... FIFTH SEMESTER – APRIL 2012 PB 5406 - IMMUNOLOGY AND IMMUNOTECHNOLOGY Date : 30-04-2012 Time : 1:00 - 4:00 ...
Tumor Escape from Immune Surveillance
Tumor Escape from Immune Surveillance

< 1 ... 400 401 402 403 404 405 406 407 408 ... 553 >

Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report