• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
First, Second Line Immunity
First, Second Line Immunity

... Mucous Membranes – Secreted by cells in respiratory system – trap bacteria and swept by cilia – swallowed, ...
Pathophysiology of Cancer Name
Pathophysiology of Cancer Name

Zánět
Zánět

... reactivity together with enzymes, complement activation and acute phase proteins. When phagocytic cells are activated, the synthesis of different cytokines is triggered. These cytokines are not only important in regulation of the innate reaction, but also for induction of the adaptive immune system. ...
Immune Surveillance - Columbia University
Immune Surveillance - Columbia University

... Peptides of tumor antigens; (early 10-30% partial response rate in advanced prostate CA and melanoma) practical problems:lack of knowledge of 1) tumor antigens 2) HLArestricted (available only for the most common HLA-types, 3) antigenic modulation most likely results in evasion for a small # of epit ...
Rheumatoid arthritis and myasthenia gravis as examples of
Rheumatoid arthritis and myasthenia gravis as examples of

... This Thesis is brought to you for free and open access by the Thesis/Dissertation Collections at RIT Scholar Works. It has been accepted for inclusion in Theses by an authorized administrator of RIT Scholar Works. For more information, please contact [email protected]. ...
CBS_Nov_22_05
CBS_Nov_22_05

... •Measure number of white blood cells that in vitro produce interferon-g in response to a peptide •A positive result means that the immune system have earlier reacted to the peptide (during a response ot a vaccine/natural infection) ...
File
File

... 11. Subunit (recombinant) – vaccines with few side effects; uses fragments of microorganisms to create an immune response; created using genetic engineering techniques to insert the genes of an antigen into another organism; includes hepatitis B 12. Conjugated – fairly new vaccines; designed for chi ...
Slide 1 - HIV Research Catalyst Forum
Slide 1 - HIV Research Catalyst Forum

... machine process that gives each T-cell one out of 25 million or so possible TCRs. • A newly made T-cell leaves the thymus to patrol around the body looking for an epitope that fits its TCR. At this stage the T-cell is called “naïve.” HIV Research Catalyst Forum April 21, 2010 ...
Considerations to overcome downstream resistance to melanoma
Considerations to overcome downstream resistance to melanoma

... Recognition of class I MHC-restricted tumor antigen peptides by CD8+ CTL Antigen discovery: • Quickly led to vaccine clinical trials • Based on notion that fundamental defect in patients is failed T cell priming • Results: Vaccines often increase specific CD8+ T cells in blood • Nonetheless, tumor ...
Immunity - sjebiol
Immunity - sjebiol

...  Role is unknown IgE (single molecule)  Present in allergic reactions IgG (single molecule)  Able to cross placenta and present in milk  Active against viruses and some bacteria IgM (five molecules)  Active against some bacteria and viruses ...
Stem Cell Notes
Stem Cell Notes

... • They are flatworms that have all 3 germ layers • Acoelomate-no true coelom, but have a digestive tract w a single opening • May reproduce asexually by spontaneous fissionconstrict in middle, breaking in half or sexually • Sexual reproduction both sexes are in same organism; both sperm and eggs are ...
Dynamic Nature of Noncoding RNA Regulation of Adaptive Immune
Dynamic Nature of Noncoding RNA Regulation of Adaptive Immune

... higher in CD4+ cells [20]. miR-150 upregulation in this context could be important to downregulate genes associated with an immature phenotype, such as NOTCH 3, which has been identified as a target of miR-150 [20]. The observation that downregulation of miR-150 confers a growth advantage to transfo ...
Host Defences, Microbial Evasion & Virulence Factors
Host Defences, Microbial Evasion & Virulence Factors

... Network of polymers (polysaccharide or protein) covering bacterial surface - S.pyogenes capsule: hyaluronic acid - S.pneumonia capsule: polysaccharide Prevent C3 convertase formation by failing to bind serum protein B (no complement activation) Antibody formation to capsule can be protective (vaccin ...
transports lymph
transports lymph

... Nucleus round, kidney-shaped, or horseshoe-shaped; contains more cytoplasm than does lymphocyte; 12–20 μm in diameter ...
Word File - University of Georgia College of Veterinary Medicine
Word File - University of Georgia College of Veterinary Medicine

... The types and level of fats in the neonatal diet are also important in immune development. In attempts to provide altered fat profiles in pork have lead to changes in the amount and type of unsaturated fats in the diets of neonatal swine (14). The type and level of specific fats in the diet have a s ...
Immunity and Health - PubContent test page
Immunity and Health - PubContent test page

... the body encounters a slightly different form with each new flu season, and therefore a different set of antigens. ...
Molecular Cloning, High Level Expression and Activity
Molecular Cloning, High Level Expression and Activity

... cause allergic diseases and attenuate the detrimental inflammation associated with debilitating human pathologies, such as IBD, diabetes and multiple sclerosis (MS). The dual role of IL–25 seems to be linked its ability to control the function of various immune and non-immune cells with the downstre ...
TUMOR IMMUNOLOGY
TUMOR IMMUNOLOGY

... malignancies, particularly colo-rectal cancers. They may also rise in some non-malignant conditions (such as chronic cirrhosis, pulmonary emphysema and heavy smoking). Levels that are 4-5 times normal have been used to predict recurrence of colo-rectal tumors. ...
Autoimmunity and Autoimmune Diseases
Autoimmunity and Autoimmune Diseases

... immunology ...
Document
Document

... Describe the different functions performed by the two subpopulations of NK cells in the blood and how they are distinguished. B. How does this compare with NK-cell subpopulations in other tissues? 3–38 The function of uterine NK cells (uNK) is to _____. a. kill virus-infected cells b. secrete growth ...
Mechanisms of neutrophil accumulation in obstructive airways disease
Mechanisms of neutrophil accumulation in obstructive airways disease

... innate immune response in these participants. We propose that alterations in the innate immune system potentiate an exaggerated neutrophil effector response which is observed in COPD and neutrophilic asthma. This project will significantly extend our understanding of obstructive airway disease. In p ...
Reasons why there is a high incidence of septic shock
Reasons why there is a high incidence of septic shock

... Therapy of type I Antihistamines have been the most useful drugs for symptoms of allergic rhinitis  They bind to the histamine receptor and block the binding of histamine  The H1 receptors are blocked by the classical antihistamines, whereas the H2 receptors are blocked by a newer class of antihi ...
emboj2009118-sup
emboj2009118-sup

... with sortilin and FLAG-NRH2 (293-SN) were treated with N-glycanase or not (37°C, 6 hours) following the manufacturer’s instruction (ProZyme, San Leandro, CA), and subjected to Western blot analysis. Arrowheads indicate that NRH2 is heavily N-glycosylated, but the extent of Nglycosylation slightly va ...
File
File

... four bouts of diarrhea which persisted for 3–5 days each time. • Joe also was not gaining weight as rapidly as was expected during this time and was diagnosed with “failure to thrive.” •At four months old, he developed another ear infection. Cultures revealed Pseudomonas aeroginosa, an opportunistic ...
Answers / Solutions
Answers / Solutions

... 7. What is hepatitis? Mention its types. It is the inflammation of liver where the hepatocytes are either damaged or destroyed. It is due to the viral infections by the strains of Hepatitis A, B, C, D and E virus, known as Viral hepatitis. Toxic effects of drugs like aspirin, paracetamol, mushroom p ...
< 1 ... 336 337 338 339 340 341 342 343 344 ... 553 >

Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report