Prolonged suckling period in organic piglet production – Effects on
... we vaccinated piglets at different times with a “known” (by vaccination of dam) and an “unknown” antigen and analysed the plasma for immunoglobulin G (IgG) concentration and the antigen-specific IgG antibodies by ELISA. Two farrowing cycles of 36 sows were recorded. Time of vaccination did not influ ...
... we vaccinated piglets at different times with a “known” (by vaccination of dam) and an “unknown” antigen and analysed the plasma for immunoglobulin G (IgG) concentration and the antigen-specific IgG antibodies by ELISA. Two farrowing cycles of 36 sows were recorded. Time of vaccination did not influ ...
Bats are reservoir hosts of several high
... human diseases, including Nipah virus, Marburg virus and rabies virus. They also harbor many other viruses that are thought to have caused disease in humans after spillover into intermediate hosts, including SARS and MERS coronaviruses. As is usual with reservoir hosts, these viruses apparently caus ...
... human diseases, including Nipah virus, Marburg virus and rabies virus. They also harbor many other viruses that are thought to have caused disease in humans after spillover into intermediate hosts, including SARS and MERS coronaviruses. As is usual with reservoir hosts, these viruses apparently caus ...
Sequence analysis of T-cell repertoires in health and disease
... Box 1 T-cell repertoire biology In the genome, there are no loci that have greater complexity or extend a deeper and broader reach into human biology than those encoding the antigen receptors of T cells and B cells. The choreographed programs of stochastic recombination that unfold at these loci dur ...
... Box 1 T-cell repertoire biology In the genome, there are no loci that have greater complexity or extend a deeper and broader reach into human biology than those encoding the antigen receptors of T cells and B cells. The choreographed programs of stochastic recombination that unfold at these loci dur ...
28-29_Per_tolerance_Regulatory T-cells_LA
... Prediction: What will be the consequence of eliminating IL-2 or the IL-2 receptor? Surprising conclusion from IL-2 knock out mice: the non-redundant function of IL-2 is in controlling immune responses (generalized autoimmune disease). In humans, CD25 deficiency causes a syndrome described as IPEX-li ...
... Prediction: What will be the consequence of eliminating IL-2 or the IL-2 receptor? Surprising conclusion from IL-2 knock out mice: the non-redundant function of IL-2 is in controlling immune responses (generalized autoimmune disease). In humans, CD25 deficiency causes a syndrome described as IPEX-li ...
Interferons as Therapeutic Agents in Infectious Diseases
... being explored, but could be promising. Introduction Interferons (IFNs) are attractive biological response modifiers for use as therapeutic agents in infectious diseases because they have both antiviral and immunomodulatory activity. Their name even comes from the fact that they can “interfere” with ...
... being explored, but could be promising. Introduction Interferons (IFNs) are attractive biological response modifiers for use as therapeutic agents in infectious diseases because they have both antiviral and immunomodulatory activity. Their name even comes from the fact that they can “interfere” with ...
Active Infection and RIG-I Signaling Influenza A Virus Infection Is
... activation, the mast cell response can be separated into two distinct phases: immediate degranulation and secretion of stored mediators and delayed secretion of de novo–synthesized mediators. The immediate response is characterized by release of histamine, serotonin, tryptases, chymases, and TNF-a, ...
... activation, the mast cell response can be separated into two distinct phases: immediate degranulation and secretion of stored mediators and delayed secretion of de novo–synthesized mediators. The immediate response is characterized by release of histamine, serotonin, tryptases, chymases, and TNF-a, ...
Slides 12.1
... Self Tolerance Breakdown ________________ lymphocyte programming Appearance of self-proteins in the circulation that have not been exposed to the immune system Eggs Sperm Eye lens Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
... Self Tolerance Breakdown ________________ lymphocyte programming Appearance of self-proteins in the circulation that have not been exposed to the immune system Eggs Sperm Eye lens Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
Human Invariant Natural Killer T cells possess
... very shortly after antigenic stimulation.6,7 iNKT cells produce a variety of cytokines, among them the Th1 cytokines interferon (IFN)-γ and tumor necrosis factor (TNF)-α as well as Th2-type cytokines like interleukin (IL)-4, IL-5, IL10, and IL-13, chemokines and growth factors.8,9 This cytokine secr ...
... very shortly after antigenic stimulation.6,7 iNKT cells produce a variety of cytokines, among them the Th1 cytokines interferon (IFN)-γ and tumor necrosis factor (TNF)-α as well as Th2-type cytokines like interleukin (IL)-4, IL-5, IL10, and IL-13, chemokines and growth factors.8,9 This cytokine secr ...
Are Expanded at Tumor Sites Regulatory T Cells That + Foxp3 high
... Human natural regulatory CD4+ T cells comprise 5–10% of peripheral CD4+T cells. They constitutively express the IL-2Ra2 chain (CD25) and the nuclear transcription Foxp3. These cells are heterogeneous and contain discrete subsets with distinct phenotypes and functions. Studies in mice report that LAG ...
... Human natural regulatory CD4+ T cells comprise 5–10% of peripheral CD4+T cells. They constitutively express the IL-2Ra2 chain (CD25) and the nuclear transcription Foxp3. These cells are heterogeneous and contain discrete subsets with distinct phenotypes and functions. Studies in mice report that LAG ...
Effects of yoga on the autonomic nervous system
... methods of measurement. For the purpose of this paper the term ‘yoga’ is used to encompass ancient and modern mind–body techniques, including all forms of yoga and other traditions that incorporate postures, meditation, chanting or breathing techniques. Anatomy of the autonomic nervous system The AN ...
... methods of measurement. For the purpose of this paper the term ‘yoga’ is used to encompass ancient and modern mind–body techniques, including all forms of yoga and other traditions that incorporate postures, meditation, chanting or breathing techniques. Anatomy of the autonomic nervous system The AN ...
Immune Senescence A Role for Immature Myeloid Cells in
... that the bone marrow, blood, and secondary lymphoid organs of healthy aged mice possess increased numbers of immature myeloid cells that are phenotypically similar to myeloid-derived suppressor cells found in lymphoid organs of mice with progressive tumors and other pathologic conditions associated ...
... that the bone marrow, blood, and secondary lymphoid organs of healthy aged mice possess increased numbers of immature myeloid cells that are phenotypically similar to myeloid-derived suppressor cells found in lymphoid organs of mice with progressive tumors and other pathologic conditions associated ...
CD8+ T cells in Autoimmunity
... priming of adoptively transferred IGRP206-214-reactive CD8+ T cells(64). Multiple factors affect the efficiency of cross-presentation and activation of autoreactive CD8+ T cells, such as, for example, the antigen dose, the presence of immune-complex forming antibodies, or the frequency of effector c ...
... priming of adoptively transferred IGRP206-214-reactive CD8+ T cells(64). Multiple factors affect the efficiency of cross-presentation and activation of autoreactive CD8+ T cells, such as, for example, the antigen dose, the presence of immune-complex forming antibodies, or the frequency of effector c ...
innovative development strategies and applications for bispecific
... complexity involved in proliferation and survival of tumor cells, with multiple mutations and multiple and/ or redundant pathways involved, including cross-talk between pathways. Bispecific antibodies are uniquely ...
... complexity involved in proliferation and survival of tumor cells, with multiple mutations and multiple and/ or redundant pathways involved, including cross-talk between pathways. Bispecific antibodies are uniquely ...
The Tuning Innate Immune Activation by Surface
... in NLRP3 into its active form, which then associates with its adaptor protein apoptosis-associated speck-like protein (ASC) (30) through Pyrin domain interactions. This complex leads to the recruitment of pro–caspase-1 (CASP1) through caspase activation and recruitment domain (also known as CARD) in ...
... in NLRP3 into its active form, which then associates with its adaptor protein apoptosis-associated speck-like protein (ASC) (30) through Pyrin domain interactions. This complex leads to the recruitment of pro–caspase-1 (CASP1) through caspase activation and recruitment domain (also known as CARD) in ...
Novel immunodeficient Pde6b rd1 mouse model of retinitis
... showed fewer cells expressing rod and cone markers in inner nuclear layer (INL) and ganglion cell layer (GCL) of retina. Müller cells, which act as retinal progenitors during degeneration can be the reason behind the little expression of these photoreceptor markers in degenerated retina inNOD.SCID-r ...
... showed fewer cells expressing rod and cone markers in inner nuclear layer (INL) and ganglion cell layer (GCL) of retina. Müller cells, which act as retinal progenitors during degeneration can be the reason behind the little expression of these photoreceptor markers in degenerated retina inNOD.SCID-r ...
IFN-γ + CD4 T Cells
... Incorporating the Pam2Cys into peptide structures effectively triggers the TLR2 and secretion of IL-12 by DCs. TLR2 is copiously present on DCs, monocytes, and lung ...
... Incorporating the Pam2Cys into peptide structures effectively triggers the TLR2 and secretion of IL-12 by DCs. TLR2 is copiously present on DCs, monocytes, and lung ...
R.Giacomilli
... bone fail to reproduce the SC osteoblasts effects, suggesting that the factor(s) involved in this process is (are) not produced or produced in an ...
... bone fail to reproduce the SC osteoblasts effects, suggesting that the factor(s) involved in this process is (are) not produced or produced in an ...
A direct quantitative relationship between the functional properties of
... most anterior of the extrastriate areas were in bilaterally homolo30 mm posterior and slightly superior to area V5 (Table 1). Two gous positions consistent with human V5 complex8,9,18. Posterior to loci were bilaterally symmetric located immediately posterior and the V5 complex, bilateral foci of ac ...
... most anterior of the extrastriate areas were in bilaterally homolo30 mm posterior and slightly superior to area V5 (Table 1). Two gous positions consistent with human V5 complex8,9,18. Posterior to loci were bilaterally symmetric located immediately posterior and the V5 complex, bilateral foci of ac ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.