Autoimmune Destruction of Pancreatic b Cells
... Diabetes Center, Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064. E-mail: [email protected] 1075-2765 ! 2005 Lippincott Williams & Wilkins ...
... Diabetes Center, Chicago Medical School, 3333 Green Bay Road, North Chicago, IL 60064. E-mail: [email protected] 1075-2765 ! 2005 Lippincott Williams & Wilkins ...
Biological Differences Between the Sexes and
... Animal models, which are largely free of confounders related to exposure and diagnosis, have been used to address the contribution of physiological factors to sex bias in tuberculosis. Historical data are somewhat conflicting. In the 1940s, Izzo and Circado found that castration of both male and fema ...
... Animal models, which are largely free of confounders related to exposure and diagnosis, have been used to address the contribution of physiological factors to sex bias in tuberculosis. Historical data are somewhat conflicting. In the 1940s, Izzo and Circado found that castration of both male and fema ...
the vagus nerve - European Medical Journal
... the DMV, which project vagal efferents to the spleen. In this way, the vagus nerve is able to modulate the splenic immune response.104-106 The immune system does not only communicate with the brain via the circulation. In the case of more localised peripheral inflammation, in which the amount of pr ...
... the DMV, which project vagal efferents to the spleen. In this way, the vagus nerve is able to modulate the splenic immune response.104-106 The immune system does not only communicate with the brain via the circulation. In the case of more localised peripheral inflammation, in which the amount of pr ...
introduction to medical parasitology
... Medical Parasitology is the branch of medical sciences dealing with organisms (parasites) which live temporarily or permanently, on or within the human body (host). There are different types of parasites and hosts. The competition for supremacy that takes place between the host and the parasite is r ...
... Medical Parasitology is the branch of medical sciences dealing with organisms (parasites) which live temporarily or permanently, on or within the human body (host). There are different types of parasites and hosts. The competition for supremacy that takes place between the host and the parasite is r ...
Marginal zone B-cells, a gatekeeper of innate
... Keywords: Staphylococcus aureus, Peptostreptococcus magnus, HIV-1, Simian immunodeficiency virus, cynomolgus macaque, superantigen, protein A ...
... Keywords: Staphylococcus aureus, Peptostreptococcus magnus, HIV-1, Simian immunodeficiency virus, cynomolgus macaque, superantigen, protein A ...
Performance-enhancing effects of dietary nucleotides
... of a nitrogen-containing base, ribose or deoxyribose, and one or more phosphate groups. They build the structure of nucleic acids (such as DNA and RNA) and energy-rich molecules (e.g. adenosine triphosphate, ATP), and act as signaling molecules and/or metabolic co-factors in human metabolism. Utiliz ...
... of a nitrogen-containing base, ribose or deoxyribose, and one or more phosphate groups. They build the structure of nucleic acids (such as DNA and RNA) and energy-rich molecules (e.g. adenosine triphosphate, ATP), and act as signaling molecules and/or metabolic co-factors in human metabolism. Utiliz ...
Document
... antibodies directed against surface antigens (usually antihuman leukocyte antigen [HLA]) on the T lymphocytes of the donor. If antidonor cytotoxic antibodies are present, the donor is unacceptable because the recipient's antibodies will immediately attack the new kidney and rapidly destroy it (hyper ...
... antibodies directed against surface antigens (usually antihuman leukocyte antigen [HLA]) on the T lymphocytes of the donor. If antidonor cytotoxic antibodies are present, the donor is unacceptable because the recipient's antibodies will immediately attack the new kidney and rapidly destroy it (hyper ...
Acute effects of tobacco smoke on human
... following chronic tobacco smoke exposure. Human studies with chronic cigarette smokers have confirmed these findings [13–15]. The highest numbers of mDCs with a Langerhans’ cell phenotype are found in the airways of smokers with COPD [6] or PLCH [16]. The present study is the first to demonstrate th ...
... following chronic tobacco smoke exposure. Human studies with chronic cigarette smokers have confirmed these findings [13–15]. The highest numbers of mDCs with a Langerhans’ cell phenotype are found in the airways of smokers with COPD [6] or PLCH [16]. The present study is the first to demonstrate th ...
Exosomes: secreted vesicles and intercellular
... determined as that of exosomes, and they can be anywhere between 50–1,000 nm in diameter. Various terms have been used for these vesicles, such as “ectosomes” [18], “shed vesicles”, or “microvesicles”, but this latter term has also been used more widely for any type of vesicle, whether intra- or ext ...
... determined as that of exosomes, and they can be anywhere between 50–1,000 nm in diameter. Various terms have been used for these vesicles, such as “ectosomes” [18], “shed vesicles”, or “microvesicles”, but this latter term has also been used more widely for any type of vesicle, whether intra- or ext ...
Herpes - From Simplex to Zoster
... • Neuronal damage might be caused by ongoing viral replication ...
... • Neuronal damage might be caused by ongoing viral replication ...
Atlantic salmon type I interferons: Protection against virus infection in
... this virus usually develop circulatory disorder and large inflammatory changes at heart. The CMS disease mainly occurs to a large fish before harvesting, thus resulting in a substantial economic impact (4). Heart and skeletal muscle inflammation (HSMI) caused by PRV which belong to Reoviridae family ...
... this virus usually develop circulatory disorder and large inflammatory changes at heart. The CMS disease mainly occurs to a large fish before harvesting, thus resulting in a substantial economic impact (4). Heart and skeletal muscle inflammation (HSMI) caused by PRV which belong to Reoviridae family ...
Shen-Diabetes 2014 - Stanford Medicine
... 3Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, Ontario, Canada ...
... 3Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Research Institute (TGRI), University Health Network, Toronto, Ontario, Canada ...
CTLA-4-mediated regulatory phenotype of T-cells in tolerant lung recipients , S. Boniface*,
... with earlier studies, bronchiolitis obliterans syndrome (BOS) remains by far the most significant long-term complication and the first cause of late post-operative death, accounting for 25–30% of all deaths occurring beyond the third year after surgery [1]. In addition, BOS also causes significant l ...
... with earlier studies, bronchiolitis obliterans syndrome (BOS) remains by far the most significant long-term complication and the first cause of late post-operative death, accounting for 25–30% of all deaths occurring beyond the third year after surgery [1]. In addition, BOS also causes significant l ...
Motion sensitive cells in the macaque superior
... corollary discharge/kinaesthetic feedback may be the physiological mechanism which accounts for some effects of 'expectation'. The experiments that will be described in the present paper were aimed to clarify two issues raised by the previous experiments. First, is it possible to observe response di ...
... corollary discharge/kinaesthetic feedback may be the physiological mechanism which accounts for some effects of 'expectation'. The experiments that will be described in the present paper were aimed to clarify two issues raised by the previous experiments. First, is it possible to observe response di ...
against Oviduct Disease to Induce Immune Pathology and Protect
... through day 42 (Fig. 2A). No difference in the rate of resolution was seen among the groups. The intensity of infection with CM972 was 10-fold lower than that of CM3.1 and Nigg between days 2 and 10, but indistinguishable thereafter (Fig. 2A). Thus, mice infected with CM972, which manifests an attac ...
... through day 42 (Fig. 2A). No difference in the rate of resolution was seen among the groups. The intensity of infection with CM972 was 10-fold lower than that of CM3.1 and Nigg between days 2 and 10, but indistinguishable thereafter (Fig. 2A). Thus, mice infected with CM972, which manifests an attac ...
Local immune regulation in human pregnancy Charlotte Gustafsson
... rejected, as is often the case with organs in allogeneic transplantations. Systemic changes in maternal blood occur during pregnancy but, perhaps of greater importance, are changes in tissues locally in the uterus. The pregnant uterine endometrium, the decidua, is infiltrated by large numbers of leu ...
... rejected, as is often the case with organs in allogeneic transplantations. Systemic changes in maternal blood occur during pregnancy but, perhaps of greater importance, are changes in tissues locally in the uterus. The pregnant uterine endometrium, the decidua, is infiltrated by large numbers of leu ...
Receptors in lateral hypothalamic area involved in - AJP
... acid-receptor antagonist kynurenate effectively blocked the increase in renal sympathetic nerve response to stimulation of the IC. The most effective injection sites were in the most ventral portions of the tuberal and posterior ipsilateral LHA, lateral to the fornix. This is consistent with an ante ...
... acid-receptor antagonist kynurenate effectively blocked the increase in renal sympathetic nerve response to stimulation of the IC. The most effective injection sites were in the most ventral portions of the tuberal and posterior ipsilateral LHA, lateral to the fornix. This is consistent with an ante ...
Juno Therapeutics Adds Adenosine Receptor Antagonist Through
... tumor-protecting barrier created by the tumor-generated extracellular adenosine, Redox compiled critical intellectual property to interrogate this biology. Reversing the inhibition caused by hypoxia and adenosine has the potential to unlock T cells in even the most difficult to treat tumors. The abi ...
... tumor-protecting barrier created by the tumor-generated extracellular adenosine, Redox compiled critical intellectual property to interrogate this biology. Reversing the inhibition caused by hypoxia and adenosine has the potential to unlock T cells in even the most difficult to treat tumors. The abi ...
this publication
... 30 percent of patients survive two years after diagnosis, and less than 10 percent survive beyond five years after diagnosis. GBM is generally treated by first surgically removing the tumor then treati ...
... 30 percent of patients survive two years after diagnosis, and less than 10 percent survive beyond five years after diagnosis. GBM is generally treated by first surgically removing the tumor then treati ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.