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Autonomic Nervous System
Autonomic Nervous System

... State the components of the CNS. State the organization of the PNS. Name the effector organs innervated by the ANS. Describe the location of cell bodies of preganglionic neurons in the sympathetic nervous system. State the course of the sympathetic preganglionic fiber from the spinal cord to the sym ...
The autoimmunity of primary biliary cirrhosis and the clonal
The autoimmunity of primary biliary cirrhosis and the clonal

... The mitochondrial antigens recognized by both B- and T-cell autoimmune responses in PBC are ubiquitously expressed in all nucleated cells, and are highly conserved in phylogenesis.38 Mitochondrial 2-OADC antigens are not ‘cryptic’ to the immune system, and normally there is tolerance to these, even ...
Strep Throat
Strep Throat

... exoenzyme DNase that is a catalyst in DNA processes. Other bacteria that produce the same catalyst are Staphylococcus aureus and Serratia marcescens (Photographic Guide to Microbiology Lab). History With a disease such as strep throat, it is difficult to locate its historical origin because scientif ...
Activation of a Nonclassical NKT Cell Subset in a Transgenic
Activation of a Nonclassical NKT Cell Subset in a Transgenic

... with a role for NKT cells, depletion of NK1.1⫹ cells ablates the early acute hepatitis, while enrichment for these cells augments tissue damage (Figure 4A). Specifically, the mice that received 1 ⫻ 108 splenocytes depleted of NK1.1⫹ cells had only a trivial increase in their baseline ALT (21%) 2 day ...
The Scientific Foundations of Applied Kinesiology
The Scientific Foundations of Applied Kinesiology

... level of the spine treated. This finding supports the increased tone in muscles found through AKMMT after SMT to the level of spinal nerve supply to the tested muscle. 29 Other studies have shown both facilitation and inhibition from the same SMT event suggesting a somato-somatic and neuro-modulatin ...
Complement-mediated “bystander” damage initiates host NLRP3
Complement-mediated “bystander” damage initiates host NLRP3

... following their interaction with zymosan or other complement activators (data not shown) in the presence but not the absence of complement (Figure 1E). Two other complement activators were similarly analyzed. We previously reported that the protozoan parasite Leishmania major was an efficient activa ...
Visual Responses of Pulvinar and Collicular Neurons During Eye
Visual Responses of Pulvinar and Collicular Neurons During Eye

... and compared responses to stimulus movement during periods of fixation with those to motion caused by saccadic or pursuit eye movements. Neurons in the inferior pulvinar (PI), lateral pulvinar (PL), and superior colliculus were tested. 2. Cells in PI and PL respond to stimulus movement over a wide r ...
Exposure of leopard frogs to a pesticide mixture affects life history
Exposure of leopard frogs to a pesticide mixture affects life history

... emerging virulent pathogens or to existing forms recently introduced into habitats where they were not previously found and against which amphibian populations have not evolved an effective immune defense (Daszak et al. 1999). Long-term exposure to multiple anthropogenic stressors, such as pollutant ...
the benefits of lactic acid bacteria in yogurt
the benefits of lactic acid bacteria in yogurt

Neuroscience: the Science of the Brain
Neuroscience: the Science of the Brain

Introduction to the Skin
Introduction to the Skin

... The skin is intimately linked to other organ systems of the body, therefore systemic disease may also affect the skin (e.g. jaundice). Skin disease can also be local. There are >2000 recognised skin diseases; everyone will develop at least 1 at some point in their life (can affect neonate  elderly) ...
Expanding Allergy Treatment in Primary Care
Expanding Allergy Treatment in Primary Care

... Most studies of SLIT have been with single allergens and translation of these studies to treatment with multiple allergens needs to be further studied. Currently no FDA approved formulations in the US (studies to obtain such approval are underway) ...
tapering - دکتر حمید آقا علی نژاد
tapering - دکتر حمید آقا علی نژاد

... Decreased functional activity of the neutrophil respiratory burst Decreased natural killer cytotoxicity Decreased response to mitogen-induced T-lymphocyte proliferation Decreased concentration of mucosal immune parameters, such as secretory immunoglobulin A Impaired delayed-type hypersensitivity res ...
Immunity against Mucosal Pathogens?
Immunity against Mucosal Pathogens?

... that can recognize peptide/MHC only at high Ag density are termed low avidity CTLs, whereas those that can recognize their cognate Ag at low densities are termed high avidity CTLs (93). High avidity CTLs are essential for the effective clearance of viral infections and for the elimination of tumors. ...
The Suprachiasmatic Nucleus Gets Split: Why Does Cortisol
The Suprachiasmatic Nucleus Gets Split: Why Does Cortisol

... neurons (10) because these neurons have been implicated in controlling glucocorticoid rhythms in rats. Release of vasopressin by SCN neurons in the PVN is an important element of the hypothalamic circuit controlling corticosteroid secretion (21, 22). However, it remains unclear whether vasopressin o ...
AbD Serotec - bioNova científica sl
AbD Serotec - bioNova científica sl

... The complement system is an ancient part of the innate immune system that acts as the first line of defence in the fight against infection. It is composed of at least 30 proteins, mostly synthesised in the liver, which typically circulate as inactive precursors. Then inactive state of the protease e ...
B Cells
B Cells

... Amplifying Lymphocytes by Clonal Selection • In the body there are few lymphocytes with antigen receptors for any particular epitope ...
Nature Neuroscience - Weizmann Institute of Science
Nature Neuroscience - Weizmann Institute of Science

NIAID Biodefense Research Agenda for Category B and C Priority
NIAID Biodefense Research Agenda for Category B and C Priority

... and birds, is found in soil and surface water in countries near the equator, particularly in Asia. Human infection results from entry of organisms through broken skin, ingestion, or inhalation of contaminated water or dust. Several forms of the disease exist with incubation periods ranging from a fe ...
interactions between macroparasites and
interactions between macroparasites and

... involves T helper 1 (Th1) cells, while defenses against extracellular parasites are primarily mediated by T helper 2 (Th2) cells. The two pathways are crossregulated; cytokines (messenger molecules) produced by Th1 cells suppress Th2 immune function and vice versa (Abbas et al. 1996, Yazdanbakhsh et ...
The Role of Dopamine and Its Dysfunction as a Consequence of
The Role of Dopamine and Its Dysfunction as a Consequence of

... has been considered as an adjunctive therapy in neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease (PD) [10]. However, MAO inhibitors are used to increase DA levels and not to decrease hydrogen peroxide production. Actually, neurons have different antioxidant systems, for exampl ...
Central mechanisms regulating coordinated cardiovascular and
Central mechanisms regulating coordinated cardiovascular and

... the cutaneous vasoconstriction that is initially evoked is associated with cerebral vasodilation, such that cerebral blood flow is increased at a time when the salience of the stimulus needs to be assessed. Regardless of the physiological significance of the initial orienting reflex, however, it has ...
MINIREVIEW Mounting Evidence for Vitamin D - Direct-MS
MINIREVIEW Mounting Evidence for Vitamin D - Direct-MS

... receptor b) was increased by 1,25(OH)2D3 treatment of CD4þ T cells (52). The function of CD25þ T cells is thought to involve IL-2 signaling, which requires both the a and b chain of the IL-2 receptor (53). Inhibition of IBD symptoms by 1,25(OH)2D3 was ineffective in the IL-2 KO mouse, and IL-2 KO mi ...
Lecture 09
Lecture 09

... • Infectious diseases are still a serious global health problem – Example of bacterial pathogen of public health relevance - Example of viral pathogen of public health relevance ...
Antibody-Selected Mimics of Hepatitis C Virus Hypervariable Region
Antibody-Selected Mimics of Hepatitis C Virus Hypervariable Region

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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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