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... The TLR4 ligand LPS has been experimentally shown to be a potent adjuvant, although its extreme toxicity prevents its use in humans. The adjuvant effect of LPS is solely dependent on TLR4-mediated, MyD88dependent signaling. Efforts to eliminate the toxicity of lipid A led to the development of monop ...
Adaptive Immune System
Adaptive Immune System

... Buckley RH. Molecular defects in human severe combined immunodeficiency and approaches to immune reconstitution. Ann Rev Immunol. 2004; 22:625-55. Dranoff G. Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer. 2004; 4:11-22. Delves PJ. 2016. Merck & the Merck Manuals. Acquired Immun ...
Cortisol (Hydrocortisone)
Cortisol (Hydrocortisone)

... Cortisol is thus classified as a glucocorticoid ...
basic immunology - School of Physical Sciences
basic immunology - School of Physical Sciences

... learn about it in a stepwise manner. We will start by defining the two main functional divisions that comprise the immune system. Thereafter, we will learn about the components of these two subdivisions. The functioning of the immune system, right from the time the immune response is activated or tr ...
Exam4StudyQuestions
Exam4StudyQuestions

...  How (in detail) does a synapse transfer an action potential from one neuron to the next?  Be familiar with some examples of how various drugs influence neurotransmitters.  Some neurotransmitters are generally excitatory and others are generally inhibitory. What causes that difference in reponse ...
VCE BIOLOGY 2011 LARA SECONDARY COLLEGE COURSE
VCE BIOLOGY 2011 LARA SECONDARY COLLEGE COURSE

... This unit examines the molecules and biochemical processes that are essential for life. DNA and gene expression, protein structure / function and associated technologies are explored. Cellular communication, including the immune systems response to pathogens is investigated, as well as the impact bi ...
MCB50 Immunity and Disease 1 Bacteria Lecture Outline March 2
MCB50 Immunity and Disease 1 Bacteria Lecture Outline March 2

... adults such as military training facilities. The disease is spread from person to person via droplets of saliva or nasal secretions. The symptoms include sore throat with malaise, fever and headache. Diagnosis is made clinically and on isolation of the bacteria from a throat swab. 2. Scarlet fever T ...
Home Meeting - Unique Body Detox
Home Meeting - Unique Body Detox

... 1. It is the major endogenous antioxidant produced by the cells participating directly in the neutralization of free radicals, and well as maintaining exogenous antioxidants such as vitamin C and E in their active forms. 2. Through direct conjugation it detoxifies many foreign compounds and carcinog ...
Document
Document

... • The nature of the disease is determined by the type of dominant immune response – Th1 response: inflammation, autoantibody production; autoimmune diseases – Th2 response: IgE+eosinophil-mediated inflammation; allergic reactions – Th17 response: acute (and chronic?) inflammation; increasingly recog ...
Immune system
Immune system

... with the surface membrane and release their contents) Activation of arachidonic acid metabolism (leukotriene C4, prostaglandin D2) ...
2.4 notes
2.4 notes

... factors on the body’s disease-fighting system – Stress reducing benefits of laughter • Laughing significantly increases the level of healthprotecting beta-endorphins • Looking forward to a positive laughing experience can decrease levels of hormones such as cortisol ...
Unit 9 – Self-Care and Reducing Test Anxiety
Unit 9 – Self-Care and Reducing Test Anxiety

... reducing test anxiety Written by Kathleen McCullough-Zander, MA, RN, CTN ...
Non-specific Immunity
Non-specific Immunity

16 Nonspecific Immune Response
16 Nonspecific Immune Response

... Cytokines • Immune cells secrete more than 100 protein messengers that regulate host cell division • Involved in non-specific and specific immune defenses • Most of their actions act locally – Paracrine/autocrine agents – Some will circulate in blood and act as hormones on distant organs ...
Immune/Lympathic
Immune/Lympathic

... antigens and makes antibodies to fight them off. • The first Rh+ fetus usually has no trouble, but any of the following fetuses (if Rh+) will cause a massive secondary reaction in the mother and the antibodies will kill off the fetuses blood. • To prevent this, Rh- mothers are given Rh antibodies du ...
Immunity Talk selected slides
Immunity Talk selected slides

... ANTIGEN A substance (usually protein) recognised as 'foreign' that stimulate antibody formation ...
Omega-3 Fatty Acid-Derived Mediators of Resolution in Health and
Omega-3 Fatty Acid-Derived Mediators of Resolution in Health and

Leaky Gut Syndrome - Back In Action Chiropratic
Leaky Gut Syndrome - Back In Action Chiropratic

... occurs in the cells lining the digestive tract. This is important because, in the case of proteins and carbohydrates, only amino acids and small sugar molecules should enter the blood stream. If proteins or large sugar molecules do make their way past the intestinal barrier, your immune system says, ...
Review for Human Body Test #3 Endocrine, Excretory, Immune
Review for Human Body Test #3 Endocrine, Excretory, Immune

... 6. ____________________ Immune system (this gland helps to make antibodies when you are young) 7. ____________________ Insulin (this gland regulates blood sugar and produces digestive enzymes) 8. ____________________ Male hormones (these glands make testosterone in males) 9. ____________________ Met ...
PEER Module Test Template - Partnerships for Environmental
PEER Module Test Template - Partnerships for Environmental

... components must be prepared. Use the provided patterns to make approximately 5 bacteria cells, 2 white blood cells (macrophages), 4 red blood cells, 1 T-helper cell, 3 Bcells, 10 antibodies, and 1 messenger. The numbers can be modified to include as many or as few students as desired.  Designate th ...
The Immune System and Immunisation
The Immune System and Immunisation

... • Pathogens: disease causing agents- such asbacteria, virus, and fungi ...
Human Defence System
Human Defence System

... Comment briefly on the difficulty in classifying viruses as living organisms. Name two diseases of humans caused by viruses. Name two types of lymphocyte and state a role of each when viruses or other micro-organisms enter the blood. “Immunity that results from vaccination is effectively the same as ...
Immunological Memory And Role Of T Lymphocytes During Viral
Immunological Memory And Role Of T Lymphocytes During Viral

Immunology Notes
Immunology Notes

... to synthesize and secrete immunoglobulin (proteins with known antibody activity)  Suppressor cells reduce the humoral immunity B. Humoral immunity: also called immunoglobulin-mediated immunity Associated with circulating antibodies B cells are responsible for humoral immunity  B lymphocytes enlarg ...
Unit 4: Infectious disease
Unit 4: Infectious disease

... from infectious disease • However, natural selection (survival of the fittest) has occurred and now many bacteria that exist today are resistant to several antibiotics ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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