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FIBROMYALGIA
FIBROMYALGIA

... A large body of data suggests that FM, chronic fatigue syndrome, regional chronic pain syndromes, and certain emotional disorders that frequently coexist with FM all involve central dysregulation of the stress response system. Here, various forms of stress function as initiators or perpetuators of f ...
Stress, serotonin, and hippocampal neurogenesis
Stress, serotonin, and hippocampal neurogenesis

... development of the nervous system (Kendler et al., 2002, 2006; Kendler et al., 2004). The effect of stress, on the other hand, can be modulated by many other factors such as personality, intrapsychic conflict, and presence (or absence) of social support, which could affect how stressful events are pe ...
Strategies and Implications for Prime
Strategies and Implications for Prime

... (Fig. 7.1b–e). An understanding of the complexity of memory CD8 T cell populations is potentially critical when designing vaccinations against specific diseases. One important distinguishing characteristic that separates memory CD8 T cells from naïve cells is the overall change in anatomical distrib ...
Quantifying Adaptive Evolution in the Drosophila Immune System
Quantifying Adaptive Evolution in the Drosophila Immune System

... than the genome average. Based on the divergence between D. simulans and D. melanogaster and polymorphism in Kenyan populations of both species, we estimated that 65% of amino acid substitutions in immunity genes have been fixed by selection (95% bounds bootstrapping across genes within categories: ...
Effect of sodium fluoride on the grey matter of spinal cord in the
Effect of sodium fluoride on the grey matter of spinal cord in the

Saccade-induced activity of dorsal lateral geniculate nucleus X
Saccade-induced activity of dorsal lateral geniculate nucleus X

... The following tests were used to classify cells as X- or Y-cells (Cleland et al., 1971; Hoffmann et al., 1972). First, orthodromic latencies to electrical pulse stimulation of the optic chiasm was measured. Second, the random-square pattern was switched on and off for 1 s each to record transient an ...
English  - SciELO Costa Rica
English - SciELO Costa Rica

... In 1914, H. Plotz reported the identification of a grampositive bacillus in the blood of patients with typhus as well as their lice.11 H. da Rocha-Lima confirmed these findings in 1916;12 he named the organism Rickettsia prowazekii in honor of Ricketts and Stanislaus von Prowazek, both of whom died ...
Combined Haemophilus influenzae respiratory infection and allergic
Combined Haemophilus influenzae respiratory infection and allergic

... suppresses eosinophilic inflammation We have recently shown that infection during or after sensitisation to OVA suppresses eosinophilic allergic airways disease.17 To investigate if similar effects were induced by chronic H influenzae infection, mice were infected, allergic airways disease induced (fi ...
Thrombocytopenia in neonates
Thrombocytopenia in neonates

Oxidative stress, innate immunity, and age
Oxidative stress, innate immunity, and age

... retinal pigment epithelium (RPE) and overlying photoreceptors (also called advanced “dry” AMD), and (ii) choroidal neovascularization (CNV, also called “wet” AMD). Dry (GA) AMD is characterized by confluent areas of photoreceptor and RPE cell death, and is responsible for 10% of the legal blindness ...
Signal transducer and activator of transcription 2
Signal transducer and activator of transcription 2

against Viruses in Innate Immune Cells B Kinase in IFN Responses
against Viruses in Innate Immune Cells B Kinase in IFN Responses

... (15). However, cDCs lacking both TBK1 and IKK-i did not produce any detectable amounts of IFN-␤ or IFN-␣ in response to all viruses tested. Production of IFN-␤ in response to the viruses was similarly regulated by TBK1 and IKK-i (Fig. 3B). Moreover, macrophages induced from fetal liver in the presen ...
Forelimb use after focal cerebral ischemia in rats treated with an a2
Forelimb use after focal cerebral ischemia in rats treated with an a2

... probe (Harvard Homeothermic Blanket Control Unit, 507061). After 120 min of MCA occlusion, the filament was removed and the external carotid artery was permanently closed by electrocoagulation. In the present study, blood pressure or blood gases were not measured, because cannulation of a femoral ar ...
Molecular mechanism of alveolar macrophage polarization and cell
Molecular mechanism of alveolar macrophage polarization and cell

... 3.4.1. Polarization capability of alveolar macrophages........................................................... - 69 3.4.2. Expression and activity of immunoproteasomes in polarized alveolar macrophages .. - 71 3.4.3. Immunoproteasome function alters macrophage polarization ...................... ...
Endometritis in old mares - Pferdeheilkunde Equine Medicine
Endometritis in old mares - Pferdeheilkunde Equine Medicine

Tài liệu PDF
Tài liệu PDF

... protist species live in a variety of other aquatic and terrestrial environments, and occupy many different niches. Not all protists are microscopic and single-celled; there exist some very large multicellular species, such as the kelps. During the past two decades, the field of molecular genetics ha ...
Flavobacterium psychrophilum
Flavobacterium psychrophilum

Cyclooxygenase-2 (COX-2) in Inflammatory and Degenerative Brain
Cyclooxygenase-2 (COX-2) in Inflammatory and Degenerative Brain

in MUC1-Transgenic Mice Cells CD8 T Cells by Dendritic/Tumor
in MUC1-Transgenic Mice Cells CD8 T Cells by Dendritic/Tumor

... class I-restricted pathway to CTL (2). In contrast, exogenous proteins from the extracellular environment are processed and displayed in association with class II molecules and recognized by CD4⫹ T cells (3). Certain exogenous Ags can also be presented to CTL through cross-presentation (4 –12). Upta ...
35-2 The Nervous System
35-2 The Nervous System

... Slide 10 of 38 Copyright Pearson Prentice Hall ...
Leishmania species: models of intracellular parasitism
Leishmania species: models of intracellular parasitism

... capacity they can orchestrate the developing immune response. Thus, to initiate a successful infection parasites must gain entry into macrophages, and also withstand or circumvent their killing and degradative functions. However, to sustain a chronic infection, parasites must also ...
NOD2 Variants and Antibody Response to Microbial Antigens in
NOD2 Variants and Antibody Response to Microbial Antigens in

... evidence have implicated enteric bacteria in the pathogenesis of CD in humans. The use of antibiotics has been associated with an inconsistent treatment response in CD.10 –14 Fecal diversion has been shown to decrease the recurrence of CD in the neoterminal ileum after resection, with subsequent ins ...
The Pathogenesis of Rheumatoid Arthritis
The Pathogenesis of Rheumatoid Arthritis

... women than among men has long been recognized. The onset of rheumatoid arthritis is also associated with adverse life events. Molecular explanations for such phenomena are emerging from animal models of inflammation, which show a link between the hypothalamic–pituitary–adrenal axis and cytokine prod ...
RES-ML2-COPD_FINAL
RES-ML2-COPD_FINAL

... • Basic mechanism: innate and adaptive inflammatory immune response.1 • Airway limitation in COPD patients can occur through: • Infiltration of inflammatory cells and occlusion of airway by inflammatory exudates. • Thickening of airway walls due to repair and remodeling process—hyperactivity of epit ...
New Vistas on Amygdala Networks in Conditioned Fear
New Vistas on Amygdala Networks in Conditioned Fear

... studies have been confirmed in humans with functional magnetic resonance imaging (fMRI) techniques (Buchel et al. 1998; LaBar et al. 1998; Whalen et al. 1998), increasing the relevance of the animal model. Third, it is becoming increasingly apparent that the mechanisms underlying Pavlovian fear cond ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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