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Haptoglobin, inflammation and disease
Haptoglobin, inflammation and disease

... exhibiting strong inhibition of TH 2 cytokine release and weak inhibition of TH 1 cytokine release (Arredouani et al., 2003). This immunomodulatory role has been found to be phenotype dependent. In a recent publication it was shown that macrophages, activated by phagocytosis of Hp2-2-Hb complex thro ...
Antigenic determinant
Antigenic determinant

... small molecules in the environment and a huge array of bactierial and viral surface proteins might all act as antigens. Many times, you will see the terms antigen and microbe used interchangeably, since most antigens are derived from larger pieces of a microbe. Lymphocytes are cells found in the blo ...
BIOL242Ch20,21Lymph1OCT2012
BIOL242Ch20,21Lymph1OCT2012

... Removal of abnormal blood cells and other blood components by phagocytosis Storage of iron and other RBC products for later use or elimination Initiation of immune responses by B cells and T cells in response to antigens in circulating blood Site of lymphocyte proliferation Stores blood platelets ...
Rosacea: skin innate immunity gone awry? - PIEL
Rosacea: skin innate immunity gone awry? - PIEL

Immunity and how vaccines work
Immunity and how vaccines work

The Biology of Mind Chapter 2 PowerPoint
The Biology of Mind Chapter 2 PowerPoint

... 5. Which of the following enables voluntary control of our skeletal muscles? ANSWER A. B. C. D. ...
Introduction to Blood Cells
Introduction to Blood Cells

... the host against a specific antigen or organism. T-lymphocytes can be divided into different subtypes including T-helper (CD4+) and T-cytotoxic (CD8+) cells. T-helper lymphocytes assist in activation of other cells of the adaptive immune system through the secretion of multiple different cytokines, ...
- Medical Journal of Australia
- Medical Journal of Australia

... TNF-α has been shown to increase blood–brain barrier permeability, resulting in increased CSF leukocytosis and CNS inflammation.7 Attenuation of the inflammatory response with routine administration of corticosteroids in patients with neurotuberculosis has been shown to reduce mortality.6 However, i ...
B cell targeted therapy in autoimmunity
B cell targeted therapy in autoimmunity

Biological Response Modifiers - International Journal of ChemTech
Biological Response Modifiers - International Journal of ChemTech

... modify the host's response to pathogens with resultant beneficial prophylactic or therapeutic effects. The use of biological response modifiers or biologicals has rapidly expanded since the introduction of the first diagnostic antibodies; they are now widely employed in oncology, autoimmune disorder ...
Enteric glia: A new player in inflammatory bowel
Enteric glia: A new player in inflammatory bowel

... factor-alpha (TNFα) antibodies (Infliximab and Adalimumab) in the therapy of IBD has radically changed their management, since these drugs are effective both in controlling moderate-to-severe forms of UC and CD and providing an efficient prevention of their relapses.8 However, the longterm safety co ...
Full Text
Full Text

Another Efferent (outgoing) System Autonomic Nervous System (ANS)
Another Efferent (outgoing) System Autonomic Nervous System (ANS)

... not all interconnected. ...
chapter29_Sections 6
chapter29_Sections 6

... Alzheimer’s Disease • Alzheimer’s disease is the leading cause of dementia (loss of ability to think) • An affected person becomes increasingly confused, cannot communicate, and eventually is incapable of living independently • Affected people have a lower than normal level of ACh in the brain ...
ANS VS PNS
ANS VS PNS

... Helps the body when it is in need of energy, under stress, and in emergency situation Does this by: increases blood pressure o decrease digestion o Increase heart beat o ...
The role of polyunsaturated fatty acids in immune function
The role of polyunsaturated fatty acids in immune function

... Efforts are underway to determine if changes in the amount of dietary polyunsaturated fatty acids (PUFA) effect the immune response and progression of mycobacteriosis in striped bass. The current study, conducted at the NOAA Cooperative Oxford Laboratory, seeks to elucidate the underlying mechanisms ...
Synaptic receptors, neurotransmitters and brain modulators
Synaptic receptors, neurotransmitters and brain modulators

... through the vagus and sympaticus. Vomiting center is also affected by the emotions controlled by the limbic system. Certain chemical agents may stimulate the vomiting center through the area postrema of the medulla. ...
Introduction - SA Health | Protecting Services
Introduction - SA Health | Protecting Services

... body, accounting for approximately 80% of all immunoglobulin-producing cells in the body. B-Imune stimulates the GALT to produce immunoglobulin (IgA) resulting in an enhanced immune response. Intestinal health is important and a factor when talking about the immune system. The first point is that tw ...
Multicenter phase II study of matured dendritic cells pulsed with
Multicenter phase II study of matured dendritic cells pulsed with

... allogeneic melanoma cell lines [3, 4]. These cell lines were selected because they express proteins that have been identified as common melanoma antigens and they are known to trigger CD8 cytotoxic responses in vivo[5, 6]. An initial phase I/II study was performed pulsing IDD-3 with just one melanom ...
Chapter 22
Chapter 22

... Others: Histamine and kinins by vasodilation; interferon production, etc. Complement: A group of about 20 proteins in plasma activated in the form of cascade and provide protection by attacking the bacterial membrane to cause lysis. (Fig. 22-12) Interferons: Interferon is an example of cytokine (cel ...
Mature T cells
Mature T cells

... Naive T cells recognize MHC-associated peptida antigens displayed on APCs + other signal (not shown). The T cells respond by producing cytokines, such as IL-2, and expresing receptors for these cytokines, leading to an autocrine pathway of cell proliferation. The result is clonal expansion of the T ...
PATH_417_Case_1_Summary_SunnyChen
PATH_417_Case_1_Summary_SunnyChen

... membranes of platelets and monocytes Superantigens • responsible for much more severe systemic consequences. • e.g. enterotoxins and Toxic Shock Syndrome toxins ...
Test - Scioly.org
Test - Scioly.org

... 67. After puberty, the thymus a. gradually diminishes in size and becomes increasingly fibrous b. gradually increases in size and becomes decreasingly fibrous c. gradually diminishes in size and becomes decreasingly fibrous d. gradually increases in size and becomes increasingly fibrous e. stays the ...
Tumor Immunology and Immunotherapy
Tumor Immunology and Immunotherapy

... • Several lines of evidence support this idea. ...
Janeway's Immunology
Janeway's Immunology

... The alternative pathway is activated spontaneous depostion of C3 on cell surface. Failure to down-regulate C3 activation leads to opsonization of microbes. ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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