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neurons
neurons

... brain. Theses networks are complex and modify with growth and experience. ...
- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... then activate surrounding cells to produce chemokines or adhesion molecules, thereby recruiting various inflammatory cells into the infection sites. Recruited macrophages or neutrophils are activated and ingest invading pathogens through internalizing PRRs. Subsequently, those cells kill them by pro ...
structure-function-of
structure-function-of

... – Myelin sheath • State the function of the above structures • State what is what meant by myelination • State the difference in impulse conduction between 2 year olds and adolescents and adults • Describe the effects of destroyed myelin sheaths ...
Basic Pathological Sciences Syllabus
Basic Pathological Sciences Syllabus

Regulation of the immune response by programmed cell death
Regulation of the immune response by programmed cell death

... was awarded "for their discoveries concerning the 'genetic regulation of organ development and programmed cell death'". Brenner established the nematode Caenorhabditis elegans as a model organism and studied organ and neuronal development. The first genes and gene products that control apoptosis wer ...
Physiology (Immunity) Lec.(5) Dr.Rafah Sami
Physiology (Immunity) Lec.(5) Dr.Rafah Sami

... activate both T lymphocytes and B lymphocytes at the same time. Some of the T cells that are formed, called helper cells, secrete specific substances (collectively called lymphokines) that activate the specific B lymphocytes. Indeed, without the aid of these helper T cells, the quantity of antibodie ...
The role of apoptosis in systemic lupus erythematosus
The role of apoptosis in systemic lupus erythematosus

... ‘blebs’ from fragmented apoptotic cells [46 ]. The LE cell, which has only recently been removed from the ACR criteria for SLE (because no one tests for it anymore, not because it was not specific), is itself a neutrophil that has phagocytosed apoptotic material of this sort. Apoptotic blebs can be ...
Antibodies
Antibodies

... • To eliminate the need for humanisation of the antibody, transgenic mice can be used (genetic engineering). Dangers to Humans: • There have been some deaths associated with the use of monoclonal antibodies for the treatment of multiple sclerosis. • Testing for the safety of new drugs presents dange ...
Nervous System - Buck Mountain Central School
Nervous System - Buck Mountain Central School

Histology Lymphoid system General Concepts Functions Provides
Histology Lymphoid system General Concepts Functions Provides

... b. T lymphocytes originate in bone marrow, mature in the thymus, and subsequently seed secondary lymphoid tissue. T cells differentiate into helper, memory, and cytotoxic cells. T lymphocytes provide cell-mediated immunity and assist B lymphocytes in their humoral response. c. Plasma cells different ...
The Immune System - Thornapple Kellogg High School
The Immune System - Thornapple Kellogg High School

... As B and T cells are maturing in the bone and thymus › Their antigen receptors are tested for possible ...
Kinetics of tumor-specific T-cell response development after active
Kinetics of tumor-specific T-cell response development after active

... A more detailed understanding of T cell activation and antigen processing has lead to a wealth of novel vaccination strategies that may significantly potentiate tumorspecific immunity. Thus, the identification of factors associated with the development of T cell responsiveness after vaccination rema ...
Immune Response 101
Immune Response 101

... mucous membranes. Other antibody types are also found in blood and tissue fluids. c. The primary response takes about 10-14 days to make “a substantial amount” of antibody to be effective. The secondary response is quicker because there are many T helper and B memory cells around to make more specif ...
Role of IL-12 in HIV infection and vaccine
Role of IL-12 in HIV infection and vaccine

... ABSTRACT. Among cytokines that dictate the fate of developing immune responses, IL-12 represents an important nexus for the development of type I cell-mediated immune responses (CMI). This factor is primarily produced by monocytic cell lineages in response to stimuli such as pathogen-associated mole ...
Course Objectives / Outline MLAB 1235 Immunology/Serology 1
Course Objectives / Outline MLAB 1235 Immunology/Serology 1

... State the genus and species of tick which is the vector involved in this disease as well as animals which are natural reservoirs of the ...
Can the Hair Follicle Become a Model for Studying Selected
Can the Hair Follicle Become a Model for Studying Selected

... field of IP. Consequently, ocular IP has become a subject of major recent interest, and its fundamental importance in inflammatory eye diseases is now widely accepted.3–15 However, as every investigative ophthalmologist painfully experiences sooner or later, as a tissue on which to perform in vitro ...
Host-pathogen interactions: An Overview Course instructor: Sumana
Host-pathogen interactions: An Overview Course instructor: Sumana

... Co-evolution and adaption between viruses and humans are often portrayed as a zero-sum biological arms race. Viruses enter host cells equipped with an array of mechanisms to evade the host defense responses and replicate. The rapid rate of mutation of viruses permits evolution of various methodologi ...
Neurodevelopment and degeneration
Neurodevelopment and degeneration

DRAFT PROGRAM- November 14, 2006 The 11th Biannual Meeting
DRAFT PROGRAM- November 14, 2006 The 11th Biannual Meeting

... toxicants. Disordered MT homeostasis has been associated with neurological disorders such as Parkinson’s disease (PD) Alzheimer disease (AD), amyotrophic lateral sclerosis (ALS) and stroke. Recently exogenous MT has been shown to ameliorate symptoms in a number of disease and injury models. Many una ...
Nervous System Part I Flashcards
Nervous System Part I Flashcards

... impulse travel WITHIN a neuron ...
Varsha Singh Indian Institute of Science, Bangalore, India
Varsha Singh Indian Institute of Science, Bangalore, India

... Recognition of microbial products in multicellular organisms: Role of nervous system Multi cellular organisms recognize microbe associated molecular patterns via the use of pattern recognition receptors or PRRs. They can also recognize damage associated molecular patterns or DAMPs released as a resu ...
File - CYPA Psychology
File - CYPA Psychology

Autonomic Nervous System
Autonomic Nervous System

... synaptic-like contacts of NA neurons of the sympathetic ANS - immune system activation  fever - HT neurons stimulate or inhibit heat production: heat sensitive neurons in the medial preoptic area act to reduce core body temperature by inhibiting other neurons in the HT and caudal brainstem to induc ...
Infectious disease - Journal of Biomedical Research
Infectious disease - Journal of Biomedical Research

... Abstract: Over the last decade, there has been a flurry of research on adjuvants for vaccines, and several novel adjuvants are now licensed products or in late stage clinical development. The success of adjuvants in enhancing the immune response to antigens has led many researchers to re-focus their ...
DNA Array-Based Gene Profiling in Tumor Immunology
DNA Array-Based Gene Profiling in Tumor Immunology

... amplification procedures, not much systematic assessment of their limits and biases has been documented. We devised a procedure that optimizes amplification of low-abundance RNA samples by combining RNA amplification with a templateswitching effect (41). The fidelity of RNA amplified from 1:10,000 t ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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