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Intravital Imaging of the Immune System
Intravital Imaging of the Immune System

Full Text  - Avicenna Journal of Dental Research
Full Text - Avicenna Journal of Dental Research

... pathologic outcomes. Several immune effectors function to minimize microbial interactions with host tissues (bacterial-epithelial contact). There is growing evidence from animal models indicating that certain bacteria can trigger immunopathology (18). The association between infection and autoimmune ...
Infection as a comorbidity of COPD PERSPECTIVE
Infection as a comorbidity of COPD PERSPECTIVE

... A causal relationship between bacteria and exacerbation was largely discredited when longitudinal studies showed similar rates of isolation of Streptococcus pneumoniae and Haemophilus influenzae from sputum during both acute exacerbations and stable disease [4–8]. A significant limitation of these s ...
Glutathione-Your body`s most powerful protector - Nutri-west
Glutathione-Your body`s most powerful protector - Nutri-west

... Sleep: The thalamus and hypothalamus are areas of the brain that are vulnerable to sleep-deprivation, and Tokyo Medical Center researchers showed that high levels of GSH not only promote sleep, but affect other hypothalamic controls as well. Glutathione may even detoxify neuronal tissues more active ...
CC Chemokine Receptor 4 Contributes to Innate NK and Chronic
CC Chemokine Receptor 4 Contributes to Innate NK and Chronic

Everitt et al. (2000) in The Amygdala - Rudolf Cardinal
Everitt et al. (2000) in The Amygdala - Rudolf Cardinal

... There is perhaps a tendency to assume that the amygdala alone is involved in associations between environmental stimuli and reinforcing events, especially in studies of aversive conditioning. However, not only is it clear that some forms of fear-motivated learning, such as aversive eye-blink conditi ...
Vaginal microbiota and its role in HIV transmission and infection
Vaginal microbiota and its role in HIV transmission and infection

... HIV X4 strains but not R5 strains via secretion of CXCL12 (Mselle et al., 2009). The number of leukocytes in the FRT approximately accounts for between 6% and 20% of the total number of immune cells with higher numbers in the upper FRT (Givan et al., 1997; Hickey et al., 2011), while the number of l ...
Pathogenesis of pneumonic pasteurellosis: Host
Pathogenesis of pneumonic pasteurellosis: Host

... how LKT, CPS, endotoxin and others interact with isolated cell populations such as leukocytes and endothelium. Virulence factors may cause target cell death by apoptosis or cell lysis. In addition, virulence factors often cause macrophages and other cells to produce cytokines, to release nitric oxid ...
Our focus is on vaccines
Our focus is on vaccines

in Primate STT Cells Differentially Modulate Brief
in Primate STT Cells Differentially Modulate Brief

... 1996; Miller 1998; Neugebauer et al. 1997, 2000; Schoepp et al. 1999; Schoppa and Westbrook 1997; Schrader and Tasker 1997). An emerging field of research implicates mGluRs in nociception and hyperalgesia. Whereas the first reports on the involvement of mGluRs in spinal nociceptive processing relied ...
Cerebrospinal fluid neopterin: an informative biomarker of central
Cerebrospinal fluid neopterin: an informative biomarker of central

... especially Th1-type cytokine interferon-γ (IFN-γ) (Figure 1) [3]. Other cells and cytokines have only limited potential to induce neopterin formation in vitro, but importantly tumor necrosis factor-α (TNF-α) can accelerate neopterin synthesis when initiated by IFN-γ [20]. By contrast, immunosupressa ...
Laugh your way to health
Laugh your way to health

... • Strengthen the integrity of the immune system • Inducing the release of neuropeptides from the pituitary gland, and throughout the body • Endorphins, interleukins, interferons ...
Impact of Anti-Oxidized Low- Density Lipoprotein
Impact of Anti-Oxidized Low- Density Lipoprotein

... or malondialdehyde (MDA, a final product of lipid peroxidation) is considered as being crucial in the process of atherogenesis [4,7]. Oxidatively modified LDL particles are distinguished by another receptor type, which was discovered on the surface of macrophages and termed “the scavenger receptor [ ...
Immunoprophylaxis
Immunoprophylaxis

...  antibacterial immune serum  antiviral immune serum  anti-lymphocyte gamma-globulin, ALG ...
CD40-CD154 Costimulation Transplant Arteriosclerosis in the
CD40-CD154 Costimulation Transplant Arteriosclerosis in the

... mechanisms responsible for the development of transplant arteriosclerosis in the absence of CD40-CD154 costimulation. To address this question, CD40-knockout (CD40⫺/⫺) mice were used as transplant recipients to investigate whether the development of transplant arteriosclerosis in the absence of CD40 ...
Lymphatic System
Lymphatic System

... half of head, neck, thorax and right upper limb, right lung, right side of heart, right surface of liver ...
Characterisation of interleukin-10 expression on different vascular
Characterisation of interleukin-10 expression on different vascular

... endothelial structures vessels separately. Firstly, the sinusoids are specialized structures that may expand and contract thanks to smooth muscle actin (SMA) positive (myo) fibroblasts that line these structures. Their capacitance volume is under neural regulation and may also be influenced by humor ...
Immuno-Isolation of Pancreatic Islet Allografts Using Pegylated
Immuno-Isolation of Pancreatic Islet Allografts Using Pegylated

Cross-Clade Protective Immune Responses to Influenza Viruses
Cross-Clade Protective Immune Responses to Influenza Viruses

... influenza virus-like particle (VLP) as a new generation of non-egg or non-mammalian cell culture-based candidate vaccine. Methodology/Principal Findings. We generated from a baculovirus expression system using insect cells, a non-infectious recombinant VLP vaccine from both influenza A H5N1 clade 1 ...
Hepatitis AE - Jacobi Medical Center
Hepatitis AE - Jacobi Medical Center

... enough to detect lower (protective) levels of vaccine-induced antibody  Provides protection even when administered following exposure to the virus – now preferred approach in between 1 – 40 years of age ...
Adenosine Receptors as Targets for Therapeutic Intervention
Adenosine Receptors as Targets for Therapeutic Intervention

... By lowering heart rate, and, especially, slowing AV nodal conduction, adenosine causes `pharmacological cardio version’, of particular use in AV nodal re-entrant tachycardia, but with other anti-arrhythmic uses too. In the basal forebrain accumulation of adenosine (seen with prolonged wakefulness) i ...
The Location and Function of NMDA Receptors in Cat
The Location and Function of NMDA Receptors in Cat

Fc lessons from murine mercury-induced autoimmunity. -receptors in systemic autoimmune conditions -
Fc lessons from murine mercury-induced autoimmunity. -receptors in systemic autoimmune conditions -

... hyporesponsiveness (anergy) in lymphocytes, which encounter antigen in the absence of the co-stimulatory signals that accompany inflammation [1]. ...
Intestinal Dendritic Cells Specialize to Activate Transforming Growth
Intestinal Dendritic Cells Specialize to Activate Transforming Growth

Pontine Gustatory Activity Is Altered by Electrical Stimulation in the
Pontine Gustatory Activity Is Altered by Electrical Stimulation in the

... analog signal is digitized at 20,000 Hz and templates formed during an initial sampling period (60 s). Subsequently, the matching algorithm is engaged only if the digitized voltage levels reach a prespecified value. Spikes are then included in a template only if more than a user-defined percentage o ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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