Doctoral thesis from the Department of Immunology,
... determined the toxicity of an alkaloid extract of Evanta (AEE) on eukaryotic cells in vitro and afterwards analyzed the effect of AEE on parasite growth. At 10 µg/ml we observed inhibition of Leishmania braziliensis promastigote growth while viability of eukaryotic cells was practically not affected ...
... determined the toxicity of an alkaloid extract of Evanta (AEE) on eukaryotic cells in vitro and afterwards analyzed the effect of AEE on parasite growth. At 10 µg/ml we observed inhibition of Leishmania braziliensis promastigote growth while viability of eukaryotic cells was practically not affected ...
Posttranslational Modifications of Proteins in Type 1 Diabetes: The
... autoantigens, thousands of splice variants may exist and be specific for b-cells, but proving that these proteins exist and have modified functions is an important step forward to understanding how alternative splicing may impact disease pathogenesis. Eizirik and colleagues are using next generation R ...
... autoantigens, thousands of splice variants may exist and be specific for b-cells, but proving that these proteins exist and have modified functions is an important step forward to understanding how alternative splicing may impact disease pathogenesis. Eizirik and colleagues are using next generation R ...
Effect of Maitake (Grifola frondosa) D-Fraction on - J
... mainly by the lymphocytes that introduce tumor-specific immunity, and not by non-specific immune reactions. We examined the change in the relative proportion of activated T cells to B cells in the spleen and in the inguinal lymph node. T cell activation by D-Fraction was observed in the inguinal reg ...
... mainly by the lymphocytes that introduce tumor-specific immunity, and not by non-specific immune reactions. We examined the change in the relative proportion of activated T cells to B cells in the spleen and in the inguinal lymph node. T cell activation by D-Fraction was observed in the inguinal reg ...
ma - FixHepC
... More downloadable slidesets on the mechanisms of action, efficacy, safety, and clinical integration of checkpoint inhibitors for HCC On-demand Webcast from the live symposium ...
... More downloadable slidesets on the mechanisms of action, efficacy, safety, and clinical integration of checkpoint inhibitors for HCC On-demand Webcast from the live symposium ...
Eliminating latent tuberculosis - Institute of Infectious Disease and
... association with HIV infection, resulting in dramatic increases in TB rates in sub-Saharan Africa [5]. In addition to efforts to enhance protective immunity by vaccination before infection, the size and elevated risk of the latent TB population indicate a crucial role for interventions that would re ...
... association with HIV infection, resulting in dramatic increases in TB rates in sub-Saharan Africa [5]. In addition to efforts to enhance protective immunity by vaccination before infection, the size and elevated risk of the latent TB population indicate a crucial role for interventions that would re ...
August 2011
... for the diagnosis, monitoring and treatment of AMR. (1) A separate breakout session for the pathologists was held and from that discussion a preliminary pathological grading scheme was produced. The technical and interpretative issues were discussed in greater detail in a subsequent editorial in the ...
... for the diagnosis, monitoring and treatment of AMR. (1) A separate breakout session for the pathologists was held and from that discussion a preliminary pathological grading scheme was produced. The technical and interpretative issues were discussed in greater detail in a subsequent editorial in the ...
ch21b_wcr
... and responses in immune system • Include interferons and interleukins • Interleukin 1 (IL-1) released by macrophages co-stimulates bound T cells to – Release interleukin 2 (IL-2) – Synthesize more IL-2 receptors © 2013 Pearson Education, Inc. ...
... and responses in immune system • Include interferons and interleukins • Interleukin 1 (IL-1) released by macrophages co-stimulates bound T cells to – Release interleukin 2 (IL-2) – Synthesize more IL-2 receptors © 2013 Pearson Education, Inc. ...
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... Hemolytic anemias – result from shortened RBC survival due to increased rate of destruction Pathogenesis – anemia occurs when rate of destruction exceeds ability of marrow to replace RBCs o Bone marrow – can increase rate of production 6-8 times baseline rate o Absence of anemia – doesn’t rule o ...
... Hemolytic anemias – result from shortened RBC survival due to increased rate of destruction Pathogenesis – anemia occurs when rate of destruction exceeds ability of marrow to replace RBCs o Bone marrow – can increase rate of production 6-8 times baseline rate o Absence of anemia – doesn’t rule o ...
Harvard-MIT Division of Health Sciences and Technology HST.071
... Proto-oncogenes tumor suppressor genes (p53) hormone receptors enzymes involved in steroid synthesis hypothalamic releasing hormones (ACTH related peptides) alpha interferon, other cytokines PLACENTAL METABOLISM Steroids synthesized by ovary also proteins in high concentration in human semen ovarian ...
... Proto-oncogenes tumor suppressor genes (p53) hormone receptors enzymes involved in steroid synthesis hypothalamic releasing hormones (ACTH related peptides) alpha interferon, other cytokines PLACENTAL METABOLISM Steroids synthesized by ovary also proteins in high concentration in human semen ovarian ...
Peripheral nervous system
... influence) between the sensory and motor neurons. – Slightly longer response (due to extra synaptic events) than a monosynaptic reflex arc. – Results can be much more complex; involving other spinal nerve segments, inhibition and excitation of muscles… ...
... influence) between the sensory and motor neurons. – Slightly longer response (due to extra synaptic events) than a monosynaptic reflex arc. – Results can be much more complex; involving other spinal nerve segments, inhibition and excitation of muscles… ...
Principle of the approach Vaccine Preparation
... complexes (HspCs) promoting peptide uptake into the antigen processing / presentation pathways, including the production of killer T-cells and antibodies against that pathogen (Colaco 1998). ImmBio's technology utilizes the immune system’s own antigen capture and activation mechanisms to elicit the ...
... complexes (HspCs) promoting peptide uptake into the antigen processing / presentation pathways, including the production of killer T-cells and antibodies against that pathogen (Colaco 1998). ImmBio's technology utilizes the immune system’s own antigen capture and activation mechanisms to elicit the ...
File - wilson science WEBSITE
... Inflammatory Responses • Following an injury, mast cells release histamine, which promotes changes in blood vessels; this is part of the inflammatory response • These changes increase local blood supply and allow more phagocytes and antimicrobial proteins to enter tissues • Pus, a fluid rich in whi ...
... Inflammatory Responses • Following an injury, mast cells release histamine, which promotes changes in blood vessels; this is part of the inflammatory response • These changes increase local blood supply and allow more phagocytes and antimicrobial proteins to enter tissues • Pus, a fluid rich in whi ...
Host Response and Dysfunction in the CNS during Chronic Simian
... basis for CNS dysfunction. In the chronic stable stage, nearly 2 years after infection, all animals had verified CNS functional abnormalities. Both virus and infiltrating lymphocytes (CD8⫹ T-cells) were found in the brain. Molecular analysis revealed that the expression of several immune response ge ...
... basis for CNS dysfunction. In the chronic stable stage, nearly 2 years after infection, all animals had verified CNS functional abnormalities. Both virus and infiltrating lymphocytes (CD8⫹ T-cells) were found in the brain. Molecular analysis revealed that the expression of several immune response ge ...
HDAC4 is expressed on multiple T cell lineages but dispensable for
... cells are under the stringent control of both transcriptional and post-translational modifications. Research in the transcriptional gene regulation of thymic T cell development has resulted in the identification of several lineage-specific transcription factors, such as ThPOK [11], Runx3 [12] and PL ...
... cells are under the stringent control of both transcriptional and post-translational modifications. Research in the transcriptional gene regulation of thymic T cell development has resulted in the identification of several lineage-specific transcription factors, such as ThPOK [11], Runx3 [12] and PL ...
WK11-RevApopt.
... -life cycle pause between EB and RB stages -stable association with host cell ...
... -life cycle pause between EB and RB stages -stable association with host cell ...
MUCOSAL IMMUNITY IN THE RESPIRATORY TRACT: INTRACELLULAR PATHOGENS
... immunization, unlike the i.p. route, elicited strong IgA responses in the lungs accompanied by a major influx of CD4+ T cells and a significant local production of IFN-γ. IgA, being the predominant Ig isotype at mucosal tissues, is considered a major effector molecule involved in defense mechanisms ...
... immunization, unlike the i.p. route, elicited strong IgA responses in the lungs accompanied by a major influx of CD4+ T cells and a significant local production of IFN-γ. IgA, being the predominant Ig isotype at mucosal tissues, is considered a major effector molecule involved in defense mechanisms ...
Inflammation in the Bovine Female Reproductive Tract
... Tritrichomonas foetus-are well adapted to the female genital tract and can persist for months after infection at coitus (51, 52). Both agents are noninvasive, (i.e., they are uterine lumen dwellers existing in the extracelluar compartment). Both can cause mild to moderate inflammation of the mucosae ...
... Tritrichomonas foetus-are well adapted to the female genital tract and can persist for months after infection at coitus (51, 52). Both agents are noninvasive, (i.e., they are uterine lumen dwellers existing in the extracelluar compartment). Both can cause mild to moderate inflammation of the mucosae ...
Thioaptamer decoy targeting of AP-1 proteins influences cytokine
... and enhance the induction of cytokines IL-6, IL-8 and TNF-a, while reducing the binding to AP-1 promoter elements. Administration of XBY-S2 to Pichinde virus-infected guinea pigs resulted in a significant reduction in Pichinde virus-induced mortality and enhanced the expression of cytokines from pri ...
... and enhance the induction of cytokines IL-6, IL-8 and TNF-a, while reducing the binding to AP-1 promoter elements. Administration of XBY-S2 to Pichinde virus-infected guinea pigs resulted in a significant reduction in Pichinde virus-induced mortality and enhanced the expression of cytokines from pri ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.