Chapter 7
... • Both leave circulation and move into tissue • Cells that are important in the inflammatory response ...
... • Both leave circulation and move into tissue • Cells that are important in the inflammatory response ...
Inflammation
... capillaries into the surrounding Tissues. In the earliest stages of inflammation, neutrophils are particularly prevalent, but later monocytes and lymphocytes also migrate towards the site of infection. Neutrophils line up within the capillary wall. Monocytes will clear up the debris. ...
... capillaries into the surrounding Tissues. In the earliest stages of inflammation, neutrophils are particularly prevalent, but later monocytes and lymphocytes also migrate towards the site of infection. Neutrophils line up within the capillary wall. Monocytes will clear up the debris. ...
T cell
... • Passive cell death mediated by the shortage in survival factors (cytokines) • Activation induced FasL expression sensitizes activated T cells for Fas• mediated apoptosis (AICD) • Activation induced cell death (AICD) is induced by repeated antigenic stimulation 4. Inhibition T lymphocyte activation ...
... • Passive cell death mediated by the shortage in survival factors (cytokines) • Activation induced FasL expression sensitizes activated T cells for Fas• mediated apoptosis (AICD) • Activation induced cell death (AICD) is induced by repeated antigenic stimulation 4. Inhibition T lymphocyte activation ...
List of accepted posters - Be There Or Die? The Role Of The
... Characterisation of Age Related Changes Repertoire and Phenotype within B-cell Subpopulations ...
... Characterisation of Age Related Changes Repertoire and Phenotype within B-cell Subpopulations ...
THE IMMUNE SYSTEM
... it by secreting a chemical (perforin) that makes holes in the cell membrane of the target cell. With enough holes, the cell will die, because water rushing inside the cell will induce osmotic swelling, and an influx of calcium may trigger apoptosis. ...
... it by secreting a chemical (perforin) that makes holes in the cell membrane of the target cell. With enough holes, the cell will die, because water rushing inside the cell will induce osmotic swelling, and an influx of calcium may trigger apoptosis. ...
Organs and Tissues of the Immune System
... Main site for response to blood-borne antigens and Tindependent antigens. Composed of red pulp (RBCs and macrophages) and white pulp (lymphocytes) It lodges 25% of the total lymphocytes of the body. T Cells: Periarteriolar lymphoid sheaths (PALS). B cells: Primary (resting) and secondary (activated) ...
... Main site for response to blood-borne antigens and Tindependent antigens. Composed of red pulp (RBCs and macrophages) and white pulp (lymphocytes) It lodges 25% of the total lymphocytes of the body. T Cells: Periarteriolar lymphoid sheaths (PALS). B cells: Primary (resting) and secondary (activated) ...
(white blood cells).
... • The name comes from the fact that these are basophilic • Basophils contain large cytoplasmic granules which obscure the cell nucleus under the microscope • They usually have 2 lobes in nucleus • The mast cell, a cell in tissues, has many similar characteristics. For example, both cell types store ...
... • The name comes from the fact that these are basophilic • Basophils contain large cytoplasmic granules which obscure the cell nucleus under the microscope • They usually have 2 lobes in nucleus • The mast cell, a cell in tissues, has many similar characteristics. For example, both cell types store ...
Immunology (B)
... Definition: The complement system is an important component of innate immunity. It can be activated by the classical and alternative pathways, both pathways will eventually lead to the lytic pathway which featured by the formation of MAC. Function of complement: anaphylaxis (C3a,C5a), chemotaxis (C5 ...
... Definition: The complement system is an important component of innate immunity. It can be activated by the classical and alternative pathways, both pathways will eventually lead to the lytic pathway which featured by the formation of MAC. Function of complement: anaphylaxis (C3a,C5a), chemotaxis (C5 ...
Blood
... • Hypersplenism (splenomegaly) – in a number of conditions the spleen may become enlarged. • Leukopenia: decreased in WBCs. • Thrombocytopenia: decreased in platelets. • Pancytopenia: when all three cells types are decreased. ...
... • Hypersplenism (splenomegaly) – in a number of conditions the spleen may become enlarged. • Leukopenia: decreased in WBCs. • Thrombocytopenia: decreased in platelets. • Pancytopenia: when all three cells types are decreased. ...
Airgas template
... The life span of white blood cells is relatively long, so constant renewal is not necessary to maintain normal blood levels. In neutropenia, all of the cell lines are affected, resulting in anemia, thrombocytopenia, and agranulocytosis. Infectious mononucleosis is a self-limiting disorder caused by ...
... The life span of white blood cells is relatively long, so constant renewal is not necessary to maintain normal blood levels. In neutropenia, all of the cell lines are affected, resulting in anemia, thrombocytopenia, and agranulocytosis. Infectious mononucleosis is a self-limiting disorder caused by ...
31.1 Pathogens and Human Illness
... 31.1 Pathogens and Human Illness Many body systems work to produce nonspecific responses. • Nonspecific responses are the same for every pathogen. • In inflammation, blood vessels become leaky. – white blood cells move extracellular capillary wall toward infection and space damaged tissue – charact ...
... 31.1 Pathogens and Human Illness Many body systems work to produce nonspecific responses. • Nonspecific responses are the same for every pathogen. • In inflammation, blood vessels become leaky. – white blood cells move extracellular capillary wall toward infection and space damaged tissue – charact ...
Adaptive Immune Response Traveled by: The Role of Innate
... how do infectious agents activate naive T cells,” Kim asked? To which I blithely answered: “They do so via their effects on the innate immune system.” Once I had this idea in my head, it was impossible to let go of it, and I quickly assembled my thoughts and tried them out on many colleagues. By the ...
... how do infectious agents activate naive T cells,” Kim asked? To which I blithely answered: “They do so via their effects on the innate immune system.” Once I had this idea in my head, it was impossible to let go of it, and I quickly assembled my thoughts and tried them out on many colleagues. By the ...
Quiz 2 Practice with Answers
... d. Transcription factors are kept in a granule that CTLs will release to the extracellular environment during effector function e. None of the above are true. 8. What is an important mode of action that Cytotoxic T cells (CTLs) use to kill their targets a. They secrete perforins that create pores in ...
... d. Transcription factors are kept in a granule that CTLs will release to the extracellular environment during effector function e. None of the above are true. 8. What is an important mode of action that Cytotoxic T cells (CTLs) use to kill their targets a. They secrete perforins that create pores in ...
Non-specific host defenses
... • A signal (induced by virus-cell interaction) is sent to the nucleus to synthesize (transcription and translation) interferon • Interferon is secreted from cell • Interferon binds to other host cells and induces production antiviral proteins (leads to inhibition of viral multiplication; I.e., by in ...
... • A signal (induced by virus-cell interaction) is sent to the nucleus to synthesize (transcription and translation) interferon • Interferon is secreted from cell • Interferon binds to other host cells and induces production antiviral proteins (leads to inhibition of viral multiplication; I.e., by in ...
CHAPTER 24
... Natural Killer Cells: attack cancer cells & virus infected cells by releasing chemicals that promote apoptosis (AKA-programmed cell death) [Not phagocytic] ...
... Natural Killer Cells: attack cancer cells & virus infected cells by releasing chemicals that promote apoptosis (AKA-programmed cell death) [Not phagocytic] ...
The body`s response to infection File
... which activates T-helper cells and produce memory cells T-helper cells bind with B-cells specific for the antigen, release cytokines which stimulate B-cell division to produce plasma cells which will produce antibodies specific to antigen – labelling them for easier destruction by macrophages. T-hel ...
... which activates T-helper cells and produce memory cells T-helper cells bind with B-cells specific for the antigen, release cytokines which stimulate B-cell division to produce plasma cells which will produce antibodies specific to antigen – labelling them for easier destruction by macrophages. T-hel ...
File
... and natural killer cells. As well as this, the inflammatory process helps to deal with pathogens where they are found. ...
... and natural killer cells. As well as this, the inflammatory process helps to deal with pathogens where they are found. ...
4.-autoimmunity-and
... surface proteins of the body’s own cells and surface proteins on foreign cells and therefore attacks body cells. • The immune response against our own self cells is called autoimmunity. – Rheumatoid arthritis – Type 1 diabetes – Multiple sclerosis. ...
... surface proteins of the body’s own cells and surface proteins on foreign cells and therefore attacks body cells. • The immune response against our own self cells is called autoimmunity. – Rheumatoid arthritis – Type 1 diabetes – Multiple sclerosis. ...
Innate immune system
The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑